Next Article in Journal
Triazoloquinazolines as Human A3 Adenosine Receptor Antagonists: A QSAR Study
Previous Article in Journal
Internal Test Sets Studies in a Group of Antimalarials
Int. J. Mol. Sci. 2006, 7(11), 469-484; doi:10.3390/i7110469
Article

Full Analytic Progress Curves of Enzymic Reactions in Vitro

1,* , 2
 and 2
1 Laboratory of Computational and Structural Physical Chemistry, Chemistry Department, West University of Timisoara, Pestalozzi Street No.16, Timisoara, RO-300115, Romania 2 Laboratory of Biochemistry, Chemistry Department, West University of Timisoara, Pestalozzi Street No.16, Timisoara, RO-300115, Romania
* Author to whom correspondence should be addressed.
Received: 30 August 2006 / Accepted: 18 October 2005 / Published: 2 November 2006
Download PDF [169 KB, uploaded 19 June 2014]

Abstract

Assuming the in vitro conditions for the enzyme-catalyzed reactions, the basic Michaelis-Menten description is modified in a logistic (mathematical) manner such that the inherent limitations that appear in the previous method are removed. Beside its generality, the reliability of the present approach is proved through applications on the competitive multi- and bi- substrate enzyme catalyses.
Keywords: Michaelis-Menten mechanism; W-Lambert function; Logistic function; multi- substrate kinetics; and fully competitive inhibition. Michaelis-Menten mechanism; W-Lambert function; Logistic function; multi- substrate kinetics; and fully competitive inhibition.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Share & Cite This Article

Export to BibTeX |
EndNote


MDPI and ACS Style

Putz, M.V.; Lacrama, A.-M.; Ostafe, V. Full Analytic Progress Curves of Enzymic Reactions in Vitro. Int. J. Mol. Sci. 2006, 7, 469-484.

View more citation formats

Related Articles

Article Metrics

Comments

Citing Articles

[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert