High Mobility Group A1 Regulates Transcription Levels of Oligodendrocyte Marker Genes in Cultured Oligodendrocyte Precursor Cells
Abstract
:1. Introduction
2. Materials and Methods
3. Results
4. Discussion
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
- Domingues, H.S.; Cruz, A.; Chan, J.R.; Relvas, J.B.; Rubinstein, B.; Pinto, I.M. Mechanical plasticity during oligodendrocyte differentiation and myelination. Glia 2017, 66, 5–14. [Google Scholar] [CrossRef] [PubMed]
- Zhang, R.; Zhang, Z.; Chopp, M. Function of neural stem cells in ischemic brain repair processes. J. Cereb. Blood Flow Metab. 2016, 36, 2034–2043. [Google Scholar] [CrossRef] [PubMed]
- Takebayashi, H.; Ikenaka, K. Oligodendrocyte generation during mouse development. Glia 2015, 63, 1350–1356. [Google Scholar] [CrossRef] [PubMed]
- Shen, S.; Li, J.; Casaccia-Bonnefil, P. Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain. J. Cell Biol. 2005, 169, 577–589. [Google Scholar] [CrossRef]
- Shen, S.; Sandoval, J.; Swiss, V.A.; Li, J.; Dupree, J.; Franklin, R.J.M.; Casaccia-Bonnefil, P. Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency. Nat. Neurosci. 2008, 11, 1024–1034. [Google Scholar] [CrossRef] [Green Version]
- Dugas, J.C.; Tai, Y.C.; Speed, T.P.; Ngai, J.; Barres, B.A. Functional Genomic Analysis of Oligodendrocyte Differentiation. J. Neurosci. 2006, 26, 10967–10983. [Google Scholar] [CrossRef]
- Liu, A.; Han, Y.R.; Li, J.; Sun, D.; Ouyang, M.; Plummer, M.R.; Casaccia-Bonnefil, P. The Glial or Neuronal Fate Choice of Oligodendrocyte Progenitors Is Modulated by Their Ability to Acquire an Epigenetic Memory. J. Neurosci. 2007, 27, 7339–7343. [Google Scholar] [CrossRef] [Green Version]
- Kassis, H.; Chopp, M.; Liu, X.S.; Shehadah, A.; Roberts, C.; Zhang, Z.G. Histone deacetylase expression in white matter oligodendrocytes after stroke. Neurochem. Int. 2014, 77, 17–23. [Google Scholar] [CrossRef] [Green Version]
- Lyssiotis, C.; Walker, J.; Wu, C.; Kondo, T.; Schultz, P.G.; Wu, X. Inhibition of histone deacetylase activity induces developmental plasticity in oligodendrocyte precursor cells. Proc. Natl. Acad. Sci. USA 2007, 104, 14982–14987. [Google Scholar] [CrossRef] [Green Version]
- Ye, F.; Chen, Y.; Hoang, T.; Montgomery, R.L.; Zhao, X.H.; Bu, H.; Lu, Q.R.; Hu, T.; Olson, E.N.; Clevers, H.; et al. HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction. Nat. Neurosci. 2009, 12, 829–838. [Google Scholar] [CrossRef] [Green Version]
- Jagielska, A.; Lowe, A.L.; Makhija, E.; Wroblewska, L.; Guck, J.; Franklin, R.; Shivashankar, G.V.; Van Vliet, K.J. Mechanical Strain Promotes Oligodendrocyte Differentiation by Global Changes of Gene Expression. Front. Cell. Neurosci. 2017, 11, 93. [Google Scholar] [CrossRef] [Green Version]
- Moyon, S.; Huynh, J.L.; Dutta, D.; Zhang, F.; Ma, D.; Yoo, S.; Lawrence, R.; Wegner, M.; John, G.R.; Emery, B.; et al. Functional Characterization of DNA Methylation in the Oligodendrocyte Lineage. Cell Rep. 2016, 15, 748–760. [Google Scholar] [CrossRef] [Green Version]
- Egawa, N.; Shindo, A.; Hikawa, R.; Kinoshita, H.; Liang, A.C.; Itoh, K.; Lok, J.; Maki, T.; Takahashi, R.; Lo, E.H.; et al. Differential roles of epigenetic regulators in the survival and differentiation of oligodendrocyte precursor cells. Glia 2018, 67, 718–728. [Google Scholar] [CrossRef]
- Yao, B.; Christian, K.M.; He, C.; Jin, B.Y.P.; Ming, G.-L.; Song, H. Epigenetic mechanisms in neurogenesis. Nat. Rev. Neurosci. 2016, 17, 537–549. [Google Scholar] [CrossRef]
- Ozturk, N.; Singh, I.; Mehta, A.; Braun, T.; Barreto, G. HMGA proteins as modulators of chromatin structure during transcriptional activation. Front Cell Dev. Biol. 2014, 2, 5. [Google Scholar] [CrossRef] [Green Version]
- Parisi, S.; Piscitelli, S.; Passaro, F.; Russo, T. HMGA Proteins in Stemness and Differentiation of Embryonic and Adult Stem Cells. Int. J. Mol. Sci. 2020, 21, 362. [Google Scholar] [CrossRef] [Green Version]
- Vignali, R.; Marracci, S. HMGA Genes and Proteins in Development and Evolution. Int. J. Mol. Sci. 2020, 21, 654. [Google Scholar] [CrossRef] [Green Version]
- Itoh, K.; Maki, T.; Shindo, A.; Egawa, N.; Liang, A.C.; Itoh, N.; Lo, E.H.; Lok, J.; Arai, K. Magnesium sulfate protects oligodendrocyte lineage cells in a rat cell-culture model of hypoxic–ischemic injury. Neurosci. Res. 2016, 106, 66–69. [Google Scholar] [CrossRef] [Green Version]
- Miyamoto, N.; Maki, T.; Shindo, A.; Liang, A.C.; Maeda, M.; Egawa, N.; Itoh, K.; Lo, E.K.; Lok, J.; Ihara, M.; et al. Astrocytes Promote Oligodendrogenesis after White Matter Damage via Brain-Derived Neurotrophic Factor. J. Neurosci. 2015, 35, 14002–14008. [Google Scholar] [CrossRef] [Green Version]
- Bansod, S.; Kageyama, R.; Ohtsuka, T. Hes5 regulates the transition timing of neurogenesis and gliogenesis in mammalian neocortical development. Development 2017, 144, 3156–3167. [Google Scholar] [CrossRef] [Green Version]
- Liu, A.; Li, J.; Marin-Husstege, M.; Kageyama, R.; Fan, Y.; Gelinas, C.; Casaccia-Bonnefil, P. A molecular insight of Hes5-dependent inhibition of myelin gene expression: Old partners and new players. EMBO J. 2006, 25, 4833–4842. [Google Scholar] [CrossRef]
- Levine, J.M.; Reynolds, R.; Fawcett, J.W. The oligodendrocyte precursor cell in health and disease. Trends Neurosci. 2001, 24, 39–47. [Google Scholar] [CrossRef]
- Pringle, N.P.; Mudhar, H.S.; Collarini, E.J.; Richardson, W.D. PDGF receptors in the rat CNS: During late neurogenesis, PDGF alpha-receptor expression appears to be restricted to glial cells of the oligodendrocyte lineage. Development 1992, 115, 535–551. [Google Scholar] [CrossRef]
- Dawson, M.R.; Polito, A.; Levine, J.M.; Reynolds, R. NG2-expressing glial progenitor cells: An abundant and widespread population of cycling cells in the adult rat CNS. Mol. Cell. Neurosci. 2003, 24, 476–488. [Google Scholar] [CrossRef]
- Miyamoto, N.; Tanaka, R.; Shimura, H.; Watanabe, T.; Mori, H.; Onodera, M.; Mochizuki, H.; Hattori, N.; Urabe, T. Phosphodiesterase III Inhibition Promotes Differentiation and Survival of Oligodendrocyte Progenitors and Enhances Regeneration of Ischemic White Matter Lesions in the Adult Mammalian Brain. J. Cereb. Blood Flow Metab. 2010, 30, 299–310. [Google Scholar] [CrossRef] [Green Version]
- Skihar, V.; Silva, C.; Chojnacki, A.; Döring, A.; Stallcup, W.B.; Weiss, S.; Yong, V.W. Promoting oligodendrogenesis and myelin repair using the multiple sclerosis medication glatiramer acetate. Proc. Natl. Acad. Sci. USA 2009, 106, 17992–17997. [Google Scholar] [CrossRef] [Green Version]
- Gensert, J.M.; Goldman, J.E. Endogenous Progenitors Remyelinate Demyelinated Axons in the Adult CNS. Neuron 1997, 19, 197–203. [Google Scholar] [CrossRef] [Green Version]
- Stetler, R.A.; Gao, Y.; Leak, R.K.; Weng, Z.; Shi, Y.; Zhang, L.; Chen, J.; Pu, H.; Hu, H.; Hassan, S.; et al. APE1/ref-1 facilitates recovery of gray and white matter and neurological function after mild stroke injury. Proc. Natl. Acad. Sci. USA 2016, 113, E3558–E3567. [Google Scholar] [CrossRef] [Green Version]
- Ohtomo, R.; Iwata, A.; Arai, K. Molecular Mechanisms of Oligodendrocyte Regeneration in White Matter-Related Diseases. Int. J. Mol. Sci. 2018, 19, 1743. [Google Scholar] [CrossRef] [Green Version]
- Tiane, A.; Schepers, M.; Rombaut, B.; Hupperts, R.; Prickaerts, J.; Hellings, N.; van den Hove, D.; Vanmierlo, T. From OPC to Oligodendrocyte: An Epigenetic Journey. Cells 2019, 8, 1236. [Google Scholar] [CrossRef] [Green Version]
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Egawa, N.; Hamanaka, G.; Chung, K.K.; Ishikawa, H.; Shindo, A.; Maki, T.; Takahashi, R.; Inoue, H.; Lo, E.H.; Arai, K. High Mobility Group A1 Regulates Transcription Levels of Oligodendrocyte Marker Genes in Cultured Oligodendrocyte Precursor Cells. Int. J. Mol. Sci. 2022, 23, 2236. https://doi.org/10.3390/ijms23042236
Egawa N, Hamanaka G, Chung KK, Ishikawa H, Shindo A, Maki T, Takahashi R, Inoue H, Lo EH, Arai K. High Mobility Group A1 Regulates Transcription Levels of Oligodendrocyte Marker Genes in Cultured Oligodendrocyte Precursor Cells. International Journal of Molecular Sciences. 2022; 23(4):2236. https://doi.org/10.3390/ijms23042236
Chicago/Turabian StyleEgawa, Naohiro, Gen Hamanaka, Kelly K. Chung, Hidehiro Ishikawa, Akihiro Shindo, Takakuni Maki, Ryosuke Takahashi, Haruhisa Inoue, Eng H. Lo, and Ken Arai. 2022. "High Mobility Group A1 Regulates Transcription Levels of Oligodendrocyte Marker Genes in Cultured Oligodendrocyte Precursor Cells" International Journal of Molecular Sciences 23, no. 4: 2236. https://doi.org/10.3390/ijms23042236