Next Article in Journal
MetStabOn—Online Platform for Metabolic Stability Predictions
Next Article in Special Issue
A Single Dose of Atorvastatin Applied Acutely after Spinal Cord Injury Suppresses Inflammation, Apoptosis, and Promotes Axon Outgrowth, Which Might Be Essential for Favorable Functional Outcome
Previous Article in Journal
Genome-Wide Analysis of DCL, AGO, and RDR Gene Families in Pepper (Capsicum Annuum L.)
Previous Article in Special Issue
Localized Intrathecal Delivery of Mesenchymal Stromal Cells Conditioned Medium Improves Functional Recovery in a Rat Model of Spinal Cord Injury
Article Menu
Issue 4 (April) cover image

Export Article

Open AccessReview
Int. J. Mol. Sci. 2018, 19(4), 1039; doi:10.3390/ijms19041039

Stem Cells Therapy for Spinal Cord Injury

1
Faculty of Medical Sciences, Department of Genetics, University of Kragujevac, 34000 Kragujevac, Serbia
2
Faculty of Medical Sciences, Department of Microbiology and immunology, Center for Molecular Medicine and Stem Cell Research, University of Kragujevac, 34000 Kragujevac, Serbia
3
Regenerative Processing Plant, LLC, 34176 US Highway 19 N Palm Harbor, Palm Harbor, FL 34684, USA
4
Faculty of Medical Sciences, Department of Histology and embryology, University of Kragujevac, 34000 Kragujevac, Serbia
5
Spebo Medical, 16 Norvezanska, 16000 Leskovac, Serbia
*
Author to whom correspondence should be addressed.
Received: 10 February 2018 / Revised: 26 February 2018 / Accepted: 5 March 2018 / Published: 30 March 2018
(This article belongs to the Special Issue Therapeutic Strategies to Spinal Cord Injury)
View Full-Text   |   Download PDF [947 KB, uploaded 4 April 2018]   |  

Abstract

Spinal cord injury (SCI), a serious public health issue, most likely occurs in previously healthy young adults. Current therapeutic strategies for SCI includes surgical decompression and pharmacotherapy, however, there is still no gold standard for the treatment of this devastating condition. Inefficiency and adverse effects of standard therapy indicate that novel therapeutic strategies are required. Because of their neuroregenerative and neuroprotective properties, stem cells are a promising tool for the treatment of SCI. Herein, we summarize and discuss the promising therapeutic potential of human embryonic stem cells (hESC), induced pluripotent stem cells (iPSC) and ependymal stem/progenitor cells (epSPC) for SCI. View Full-Text
Keywords: spinal cord injury; stem cells; embryonic stem cells; induced pluripotent stem cells; ependymal stem/progenitor cells spinal cord injury; stem cells; embryonic stem cells; induced pluripotent stem cells; ependymal stem/progenitor cells
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Gazdic, M.; Volarevic, V.; Harrell, C.R.; Fellabaum, C.; Jovicic, N.; Arsenijevic, N.; Stojkovic, M. Stem Cells Therapy for Spinal Cord Injury. Int. J. Mol. Sci. 2018, 19, 1039.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top