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Int. J. Mol. Sci. 2017, 18(9), 1629; doi:10.3390/ijms18091629

Overview of β-Glucans from Laminaria spp.: Immunomodulation Properties and Applications on Biologic Models

1
Graduate Program in Health Sciences, Department of Clinical Analysis and Biomedicine, State University of Maringa, Paraná 87020-900, Brazil
2
Graduate Program in Biosciences and Pathophysiology, Department of Clinical Analysis and Biomedicine, State University of Maringa, Paraná 87020-900, Brazil
3
Department of Clinical Analysis and Biomedicine, State University of Maringa, Paraná 87020-900, Brazil
*
Author to whom correspondence should be addressed.
Received: 18 June 2017 / Revised: 9 July 2017 / Accepted: 11 July 2017 / Published: 6 September 2017
(This article belongs to the Special Issue Glucan: New Perspectives on Biochemistry and Application)
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Abstract

Glucans are a group of glucose polymers that are found in bacteria, algae, fungi, and plants. While their properties are well known, their biochemical and solubility characteristics vary considerably, and glucans obtained from different sources can have different applications. Research has described the bioactivity of β-glucans extracted from the algae of the Laminaria genus, including in vivo and in vitro studies assessing pro- and anti-inflammatory cytokines, vaccine production, inhibition of cell proliferation, and anti- and pro-oxidant activity. Thus, the objective of this article was to review the potential application of β-glucans from Laminaria spp. in terms of their immunomodulatory properties, microorganism host interaction, anti-cancer activity and vaccine development. View Full-Text
Keywords: Laminaria; β-glucan; glucans; immunomodulatory properties; defense Laminaria; β-glucan; glucans; immunomodulatory properties; defense
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Bonfim-Mendonça, P.S.; Capoci, I.R.G.; Tobaldini-Valerio, F.K.; Negri, M.; Svidzinski, T.I.E. Overview of β-Glucans from Laminaria spp.: Immunomodulation Properties and Applications on Biologic Models. Int. J. Mol. Sci. 2017, 18, 1629.

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