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Int. J. Mol. Sci. 2016, 17(9), 1436; doi:10.3390/ijms17091436

Antimicrobial and Antioxidant Activity of Chitosan/Hydroxypropyl Methylcellulose Film-Forming Hydrosols Hydrolyzed by Cellulase

Department of Animal Products Technology and Quality Management, Wrocław University of Environmental and Life Sciences, 37 Chelmonskiego St., 51-630 Wrocław, Poland
Author to whom correspondence should be addressed.
Academic Editors: Antonella Piozzi and Iolanda Francolini
Received: 29 July 2016 / Revised: 18 August 2016 / Accepted: 25 August 2016 / Published: 6 September 2016
(This article belongs to the Special Issue Antimicrobial Polymers 2016)
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The aim of this study was to evaluate the impact of cellulase (C) on the biological activity of chitosan/hydroxypropyl methylcellulose (CH/HPMC) film-forming hydrosols. The hydrolytic activity of cellulase in two concentrations (0.05% and 0.1%) was verified by determination of the progress of polysaccharide hydrolysis, based on viscosity measurement and reducing sugar-ends assay. The 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging effect, the ferric reducing antioxidant power (FRAP), and microbial reduction of Pseudomonas fluorescens, Yersinia enterocolitica, Bacillus cereus, and Staphylococcus aureus were studied. During the first 3 h of reaction, relative reducing sugar concentration increased progressively, and viscosity decreased rapidly. With increasing amount of enzyme from 0.05% to 0.1%, the reducing sugar concentration increased, and the viscosity decreased significantly. The scavenging effect of film-forming solutions was improved from 7.6% at time 0 and without enzyme to 52.1% for 0.1% cellulase after 20 h of reaction. A significant effect of cellulase addition and reaction time on antioxidant power of the tested film-forming solutions was also reported. Film-forming hydrosols with cellulase exhibited a bacteriostatic effect on all tested bacteria, causing a total reduction. View Full-Text
Keywords: chitosan; hydroxypropyl methylcellulose; cellulase; antioxidant properties; antimicrobial properties chitosan; hydroxypropyl methylcellulose; cellulase; antioxidant properties; antimicrobial properties

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Zimoch-Korzycka, A.; Bobak, Ł.; Jarmoluk, A. Antimicrobial and Antioxidant Activity of Chitosan/Hydroxypropyl Methylcellulose Film-Forming Hydrosols Hydrolyzed by Cellulase. Int. J. Mol. Sci. 2016, 17, 1436.

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