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Int. J. Mol. Sci. 2016, 17(12), 2072; doi:10.3390/ijms17122072

Nutrimetabolomics: An Update on Analytical Approaches to Investigate the Role of Plant-Based Foods and Their Bioactive Compounds in Non-Communicable Chronic Diseases

1
Department of Biochemistry and Molecular Biology II, Institute of Nutrition and Food Technology “José Mataix”, Center for Biomedical Research, University of Granada, 18100 Granada, Spain
2
Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición, Ciberobn, 28029 Madrid, Spain
*
Author to whom correspondence should be addressed.
Academic Editors: Vito Verardo and David Arráez-Román
Received: 24 October 2016 / Revised: 28 November 2016 / Accepted: 3 December 2016 / Published: 9 December 2016
(This article belongs to the Special Issue Lipidomics and Glycomics: New Advances in Food Science and Nutrition)
View Full-Text   |   Download PDF [232 KB, uploaded 9 December 2016]

Abstract

Metabolomics is the study of low-weight molecules present in biological samples such as biofluids, tissue/cellular extracts, and culture media. Metabolomics research is increasing, and at the moment, it has several applications in the food science and nutrition fields. In the present review, we provide an update about the most frequently used methodologies and metabolomic platforms in these areas. Also, we discuss different metabolomic strategies regarding the discovery of new bioactive compounds (BACs) in plant-based foods. Furthermore, we review the existing literature related to the use of metabolomics to investigate the potential protective role of BACs in the prevention and treatment of non-communicable chronic diseases, namely cardiovascular disease, diabetes, and cancer. View Full-Text
Keywords: bioactive compounds; metabolomics; non-communicable chronic diseases; nutrimetabolomics; plant-based food bioactive compounds; metabolomics; non-communicable chronic diseases; nutrimetabolomics; plant-based food
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Rangel-Huerta, O.D.; Gil, A. Nutrimetabolomics: An Update on Analytical Approaches to Investigate the Role of Plant-Based Foods and Their Bioactive Compounds in Non-Communicable Chronic Diseases. Int. J. Mol. Sci. 2016, 17, 2072.

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