Int. J. Mol. Sci. 2014, 15(6), 9878-9893; doi:10.3390/ijms15069878
Review

SPECT and PET Serve as Molecular Imaging Techniques and in Vivo Biomarkers for Brain Metastases

1,* email, 1email, 2email, 2email, 3,4email, 5email and 6email
Received: 30 March 2014; in revised form: 13 May 2014 / Accepted: 14 May 2014 / Published: 3 June 2014
(This article belongs to the Special Issue Brain Metastasis 2014)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Nuclear medicine techniques (single photon emission computerized tomography, SPECT, and positron emission tomography, PET) represent molecular imaging tools, able to provide in vivo biomarkers of different diseases. To investigate brain tumours and metastases many different radiopharmaceuticals imaged by SPECT and PET can be used. In this review the main and most promising radiopharmaceuticals available to detect brain metastases are reported. Furthermore the diagnostic contribution of the combination of SPECT and PET data with radiological findings (magnetic resonance imaging, MRI) is discussed.
Keywords: brain metastases; molecular imaging; PET; SPECT; MRI; fusion imaging
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MDPI and ACS Style

Palumbo, B.; Buresta, T.; Nuvoli, S.; Spanu, A.; Schillaci, O.; Fravolini, M.L.; Palumbo, I. SPECT and PET Serve as Molecular Imaging Techniques and in Vivo Biomarkers for Brain Metastases. Int. J. Mol. Sci. 2014, 15, 9878-9893.

AMA Style

Palumbo B, Buresta T, Nuvoli S, Spanu A, Schillaci O, Fravolini ML, Palumbo I. SPECT and PET Serve as Molecular Imaging Techniques and in Vivo Biomarkers for Brain Metastases. International Journal of Molecular Sciences. 2014; 15(6):9878-9893.

Chicago/Turabian Style

Palumbo, Barbara; Buresta, Tommaso; Nuvoli, Susanna; Spanu, Angela; Schillaci, Orazio; Fravolini, Mario L.; Palumbo, Isabella. 2014. "SPECT and PET Serve as Molecular Imaging Techniques and in Vivo Biomarkers for Brain Metastases." Int. J. Mol. Sci. 15, no. 6: 9878-9893.

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