Int. J. Mol. Sci. 2012, 13(4), 5010-5018; doi:10.3390/ijms13045010
Article

Aristolactam-Type Alkaloids from Orophea enterocarpa and Their Cytotoxicities

1email, 2email, 1email, 2email, 3email, 4email and 1,* email
Received: 7 March 2012; in revised form: 27 March 2012 / Accepted: 12 April 2012 / Published: 20 April 2012
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: A new aristolactam, named enterocarpam-III (10-amino-2,3,4,6-tetramethoxy phenanthrene-1-carboxylic acid lactam, 1) together with the known alkaloid stigmalactam (2), were isolated from Orophea enterocarpa. Their structures were elucidated on the basis of interpretation of their spectroscopic data. Compounds 1 and 2 exhibited significant cytotoxicities against human colon adenocarcinoma (HCT15) cell line with IC50 values of 1.68 and 1.32 μM, respectively.
Keywords: Orophea enterocarpa; Anonaceae; aristolactam; human colon adenocarcinoma cells; cytotoxicities
PDF Full-text Download PDF Full-Text [752 KB, uploaded 19 June 2014 04:15 CEST]

Export to BibTeX |
EndNote


MDPI and ACS Style

Nayyatip, S.; Thaichana, P.; Buayairaksa, M.; Tuntiwechapikul, W.; Meepowpan, P.; Nuntasaen, N.; Pompimon, W. Aristolactam-Type Alkaloids from Orophea enterocarpa and Their Cytotoxicities. Int. J. Mol. Sci. 2012, 13, 5010-5018.

AMA Style

Nayyatip S, Thaichana P, Buayairaksa M, Tuntiwechapikul W, Meepowpan P, Nuntasaen N, Pompimon W. Aristolactam-Type Alkaloids from Orophea enterocarpa and Their Cytotoxicities. International Journal of Molecular Sciences. 2012; 13(4):5010-5018.

Chicago/Turabian Style

Nayyatip, Sanchai; Thaichana, Pak; Buayairaksa, Mongkol; Tuntiwechapikul, Wirote; Meepowpan, Puttinan; Nuntasaen, Narong; Pompimon, Wilart. 2012. "Aristolactam-Type Alkaloids from Orophea enterocarpa and Their Cytotoxicities." Int. J. Mol. Sci. 13, no. 4: 5010-5018.

Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert