Infrared Assisted Production of 3,4-Dihydro-2(1H)-pyridones in Solvent-Free Conditions
Abstract
:1. Introduction
2. Results and Discussion
3. Experimental Section
4-(4’-Fluorophenyl)-5-methoxycarbonyl-6-methyl-3,4-dihydro-2(1H)-pyridone (4c)
5-Ethoxycarbonyl 4-(4’-fluorophenyl)-6-methyl-3,4-dihydro-2(1H)-pyridone (4d)
6-Methyl-4-(2’-methylphenyl)-5-methoxycarbonyl-3,4-dihydro-2(1H)-pyridone (4g)
5-Ethoxycarbonyl-6-methyl-4-(2’-methylphenyl)-3,4-dihydro-2(1H)-pyridone (4h)
Phenylene-1’,4’-di-(4-(6-methyl-5-methoxycarbonyl-3,4-dihydro-2(1H)-pyridone)) (4k)
Phenylene-1’,4’-di-(4-(5-ethoxycarbonyl-6-methyl-3,4-dihydro-2(1H)-pyridone)) (4l)
4. Conclusions
Acknowledgments
References
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Compound | Melting point[b] (°C) | Yield[c]% |
---|---|---|
4a | 197–198(197–198) [12,28] | 75 |
4b | 168–171 | 75 |
4c | 206–208(207–209) [12,28] | 75 |
4d | 184–186(184–186) [29] | 70 |
4e | 200–202(201–201) [29] | 75 |
4f | 130–133 | 60 |
4g | oil | 70 |
4h | oil | 60 |
4i | 180–183 | 55 |
4j | 185–188 | 50 |
4k | oil | 65 |
4l | oil | 59 |
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Noguez, M.O.; Marcelino, V.; Rodríguez, H.; Martín, O.; Martínez, J.O.; Arroyo, G.A.; Pérez, F.J.; Suárez, M.; Miranda, R. Infrared Assisted Production of 3,4-Dihydro-2(1H)-pyridones in Solvent-Free Conditions. Int. J. Mol. Sci. 2011, 12, 2641-2649. https://doi.org/10.3390/ijms12042641
Noguez MO, Marcelino V, Rodríguez H, Martín O, Martínez JO, Arroyo GA, Pérez FJ, Suárez M, Miranda R. Infrared Assisted Production of 3,4-Dihydro-2(1H)-pyridones in Solvent-Free Conditions. International Journal of Molecular Sciences. 2011; 12(4):2641-2649. https://doi.org/10.3390/ijms12042641
Chicago/Turabian StyleNoguez, M. Olivia, Vanessa Marcelino, Hortensia Rodríguez, Osnieski Martín, Joel O. Martínez, Gabriel A. Arroyo, Francisco J. Pérez, Margarita Suárez, and René Miranda. 2011. "Infrared Assisted Production of 3,4-Dihydro-2(1H)-pyridones in Solvent-Free Conditions" International Journal of Molecular Sciences 12, no. 4: 2641-2649. https://doi.org/10.3390/ijms12042641