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Int. J. Mol. Sci. 2011, 12(11), 7438-7444; doi:10.3390/ijms12117438

Novel Ionic Liquid with Both Lewis and Brønsted Acid Sites for Michael Addition

Zhejiang Medicine Co. Ltd., Xinchang Pharmaceutical Factory, Zhejiang 312500, China
College of Chemistry & Chemical Engineering, Shaoxing University, Shaoxing 312000, China
Author to whom correspondence should be addressed.
Received: 29 September 2011 / Revised: 19 October 2011 / Accepted: 19 October 2011 / Published: 28 October 2011
(This article belongs to the Section Biomaterial Sciences)


Ionic liquid with both Lewis and Brønsted acid sites has been synthesized and its catalytic activities for Michael addition were carefully studied. The novel ionic liquid was stable to water and could be used in aqueous solution. The molar ratio of the Lewis and Brønsted acid sites could be adjusted to match different reactions. The results showed that the novel ionic liquid was very efficient for Michael addition with good to excellent yields within several min. Operational simplicity, high stability to water and air, small amount used, low cost of the catalyst used, high yields, chemoselectivity, applicability to large-scale reactions and reusability are the key features of this methodology, which indicated that this novel ionic liquid also holds great potential for environmentally friendly processes. View Full-Text
Keywords: novel ionic liquid; Michael addition; Lewis and Brønsted acid sites novel ionic liquid; Michael addition; Lewis and Brønsted acid sites

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Jiang, X.; Ye, W.; Song, X.; Ma, W.; Lao, X.; Shen, R. Novel Ionic Liquid with Both Lewis and Brønsted Acid Sites for Michael Addition. Int. J. Mol. Sci. 2011, 12, 7438-7444.

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