Next Article in Journal
Variation in Dehydration Tolerance, ABA Sensitivity and Related Gene Expression Patterns in D-Genome Progenitor and Synthetic Hexaploid Wheat Lines
Next Article in Special Issue
Calculation of the Aqueous Thermodynamic Properties of Citric Acid Cycle Intermediates and Precursors and the Estimation of High Temperature and Pressure Equation of State Parameters
Previous Article in Journal / Special Issue
Precambrian Lunar Volcanic Protolife
Int. J. Mol. Sci. 2009, 10(6), 2722-2732; doi:10.3390/ijms10062722

Amino Acid Synthesis in a Supercritical Carbon Dioxide - Water System

1,* , 3
1, 2
1 International Clinical Research Centre, Research Institute, International Medical Centre of Japan, 1-21-1 Toyama, Shinjuku-ku, Tokyo, Japan 2 Department of Molecular Cell Biology, Institute of DNA Medicine, Jikei University School of Medicine, 3-25-8 Nishi-shimbashi, Minato-ku, Tokyo, Japan 3 Sekisui Chemical Co., Ltd., 2-1 Hyakuyama, Shimamoto-cho, Mishima-gun, Osaka, Japan
* Authors to whom correspondence should be addressed.
Received: 21 May 2009 / Revised: 5 June 2009 / Accepted: 8 June 2009 / Published: 15 June 2009
(This article belongs to the Special Issue Origin of Life)
View Full-Text   |   Download PDF [458 KB, uploaded 19 June 2014]   |  


Mars is a CO2-abundant planet, whereas early Earth is thought to be also CO2-abundant. In addition, water was also discovered on Mars in 2008. From the facts and theory, we assumed that soda fountains were present on both planets, and this affected amino acid synthesis. Here, using a supercritical CO2/liquid H2O (10:1) system which mimicked crust soda fountains, we demonstrate production of amino acids from hydroxylamine (nitrogen source) and keto acids (oxylic acid sources). In this research, several amino acids were detected with an amino acid analyzer. Moreover, alanine polymers were detected with LC-MS. Our research lights up a new pathway in the study of life’s origin.
Keywords: supercritical carbon oxide; amino acid; prebiotic chemistry; soda fountain; Mars supercritical carbon oxide; amino acid; prebiotic chemistry; soda fountain; Mars
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote |
MDPI and ACS Style

Fujioka, K.; Futamura, Y.; Shiohara, T.; Hoshino, A.; Kanaya, F.; Manome, Y.; Yamamoto, K. Amino Acid Synthesis in a Supercritical Carbon Dioxide - Water System. Int. J. Mol. Sci. 2009, 10, 2722-2732.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here


[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert