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Recent Advances in X-ray Sensing and Imaging

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Sensing and Imaging".

Deadline for manuscript submissions: 30 July 2024 | Viewed by 885

Special Issue Editor


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Guest Editor
Center for Diagnostic and Radiological Health, U.S. Food and Drug Administration, Silver Spring, MD 20993, USA
Interests: diagnostic imaging; X-ray spectral imaging; quantitative imaging; statistical assessment; machine learning; clinical study design

Special Issue Information

Dear Colleagues,

The realm of X-ray imaging and sensing is currently undergoing a transformative era marked by remarkable advancements in detector technologies. Photon-counting X-ray detectors (PCDs) and high-spatial-resolution detectors, particularly those utilizing direct conversion methods, are leading this revolution. These technological leaps have significantly enhanced spectral imaging applications, heralding a new era of ultra-high-resolution computed tomography (CT) and pioneering applications in fields like X-ray phase-contrast imaging and X-ray coherent scatter imaging.

The impacts of these advancements are profound. PCDs, for instance, allow for the simultaneous capturing and discernment of spectral information, a feat previously unattainable with traditional detectors. This capability is pivotal in differentiating between materials and tissues based on their energy-dependent attenuation characteristics, opening new avenues in diagnostic imaging and material sciences.

Furthermore, the development of high-spatial-resolution detectors has enabled unprecedented detail in imaging, pushing the boundaries of what can be visualized and diagnosed. Enhanced resolution is particularly beneficial in fields requiring meticulous detail, such as neurology, orthopedics, and oncology.

Major CT manufacturers are actively developing PCD prototypes, demonstrating the significant industry investment and recognition of the potential for these innovative detectors to transform medical diagnostics and industrial applications. This is further evidenced by the early adoption of these detectors in clinical practice.

The purpose of this Special Issue is to showcase the latest developments of X-ray sensing and imaging technologies and explore their future trajectories. We aim to bring together a diverse range of research, covering (but not limited to) the following topics:

  1. Innovations in photon-counting X-ray detectors and their applications.
  2. Advances in high-spatial-resolution detectors using direct conversion methods.
  3. The role of these technologies in enhancing spectral imaging applications.
  4. The integration and impact of these detectors in ultra-high-resolution CT.
  5. Emerging applications in X-ray phase-contrast imaging and X-ray coherent scatter imaging.
  6. Clinical and industrial case studies demonstrating the practical applications of these advanced detectors.
  7. Quantitative data (e.g., improved resolution, reduced radiation dose) illustrating the impact of these advancements.

We invite researchers and practitioners from academia and industry to contribute their latest findings, reviews, and perspectives on these exciting developments.

Dr. Bahaa Ghammraoui
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • X-ray imaging
  • photon-counting detectors
  • spectral imaging
  • high-spatial-resolution detectors
  • direct conversion detectors
  • X-ray phase-contrast imaging
  • X-ray coherent scatter imaging
  • material characterization
  • machine learning in imaging
  • industrial X-ray applications

Published Papers (1 paper)

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Research

16 pages, 9035 KiB  
Article
Nanoscale Three-Dimensional Imaging of Integrated Circuits Using a Scanning Electron Microscope and Transition-Edge Sensor Spectrometer
by Nathan Nakamura, Paul Szypryt, Amber L. Dagel, Bradley K. Alpert, Douglas A. Bennett, William Bertrand Doriese, Malcolm Durkin, Joseph W. Fowler, Dylan T. Fox, Johnathon D. Gard, Ryan N. Goodner, James Zachariah Harris, Gene C. Hilton, Edward S. Jimenez, Burke L. Kernen, Kurt W. Larson, Zachary H. Levine, Daniel McArthur, Kelsey M. Morgan, Galen C. O’Neil, Nathan J. Ortiz, Christine G. Pappas, Carl D. Reintsema, Daniel R. Schmidt, Peter A. Schultz, Kyle R. Thompson, Joel N. Ullom, Leila Vale, Courtenay T. Vaughan, Christopher Walker, Joel C. Weber, Jason W. Wheeler and Daniel S. Swetzadd Show full author list remove Hide full author list
Sensors 2024, 24(9), 2890; https://doi.org/10.3390/s24092890 - 30 Apr 2024
Viewed by 521
Abstract
X-ray nanotomography is a powerful tool for the characterization of nanoscale materials and structures, but it is difficult to implement due to the competing requirements of X-ray flux and spot size. Due to this constraint, state-of-the-art nanotomography is predominantly performed at large synchrotron [...] Read more.
X-ray nanotomography is a powerful tool for the characterization of nanoscale materials and structures, but it is difficult to implement due to the competing requirements of X-ray flux and spot size. Due to this constraint, state-of-the-art nanotomography is predominantly performed at large synchrotron facilities. We present a laboratory-scale nanotomography instrument that achieves nanoscale spatial resolution while addressing the limitations of conventional tomography tools. The instrument combines the electron beam of a scanning electron microscope (SEM) with the precise, broadband X-ray detection of a superconducting transition-edge sensor (TES) microcalorimeter. The electron beam generates a highly focused X-ray spot on a metal target held micrometers away from the sample of interest, while the TES spectrometer isolates target photons with a high signal-to-noise ratio. This combination of a focused X-ray spot, energy-resolved X-ray detection, and unique system geometry enables nanoscale, element-specific X-ray imaging in a compact footprint. The proof of concept for this approach to X-ray nanotomography is demonstrated by imaging 160 nm features in three dimensions in six layers of a Cu-SiO2 integrated circuit, and a path toward finer resolution and enhanced imaging capabilities is discussed. Full article
(This article belongs to the Special Issue Recent Advances in X-ray Sensing and Imaging)
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