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Antioxidants 2014, 3(2), 278-287; doi:10.3390/antiox3020278

Antioxidant and Free Radical Scavenging Capacity of Seed and Shell Essential Oils Extracted from Abrus precatorius (L)

1
Department of Chemistry, University of Lagos, Yaba, Lagos 101017, Nigeria
2
Department of CFET, Federal Institute of Industrial Research, Lagos 100261, Nigeria
3
Department of Botany, University of Fort Hare, Alice 5700, South Africa
*
Author to whom correspondence should be addressed.
Received: 10 January 2014 / Revised: 28 February 2014 / Accepted: 21 March 2014 / Published: 15 April 2014
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Abstract

Essential oils from plants have been proven safe as natural antioxidants, and few are already marketed as digestive enhancers as well as in prevention of several degenerative diseases. This study evaluated the antioxidant capacity of seed and shell essential oils of Abrus precatorius (L), a herb used for ethno-medicinal practices in Nigeria. The essential oils were obtained by hydro-distillation. The ability of the oils to act as hydrogen/electrons donor or scavenger of radicals were determined by in-vitro antioxidant assays using 2,2-diphenyl-2-picryl-hydrazyl free radical (DPPH.) scavenging; 2,2′-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical scavenging; lipid peroxide and nitric oxide radicals scavenging assays. The IC50 of the seed and shell oils (2.10 mg/mL and 1.20 mg/mL respectively) showed that antioxidant activity is higher than that for the standard drugs (3.20 mg/mL and 3.40 mg/mL) for the nitric oxide scavenging assay. The lipid peroxidation radical activity of the oils were similar to vitamin C, weak DPPH and ABTS radical scavenging activities were discovered in comparison to vitamin C and rutin. Generally, in the four antioxidant assays, a significant correlation existed between concentrations of the oils and percentage inhibition of free radicals and lipid peroxidation. The composition of A. precatorius essential oils reported earlier may account for their antioxidant capacity. View Full-Text
Keywords: Abrus precatorius; essential oils; DPPH; ABTS; lipid peroxidation; nitric oxide Abrus precatorius; essential oils; DPPH; ABTS; lipid peroxidation; nitric oxide
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Okoh, S.O.; Asekun, O.T.; Familoni, O.B.; Afolayan, A.J. Antioxidant and Free Radical Scavenging Capacity of Seed and Shell Essential Oils Extracted from Abrus precatorius (L). Antioxidants 2014, 3, 278-287.

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