Next Article in Journal
Mechanical Behavior of Ultrafine Gradient Grain Structures Produced via Ambient and Cryogenic Surface Mechanical Attrition Treatment in Iron
Next Article in Special Issue
Synergic Role of Self-Interstitials and Vacancies in Indium Melting
Previous Article in Journal
Mechanical and Structural Investigation of Porous Bulk Metallic Glasses
Article Menu

Export Article

Open AccessReview
Metals 2015, 5(2), 934-975; doi:10.3390/met5020934

Nanotoxicology of Metal Oxide Nanoparticles

1,2,†,* and 2,3,4,†
1
Exact and Earth Sciences Department, Universidade Federal de São Paulo, Rua São Nicolau, 210, Diadema, São Paulo 0991330, Brazil
2
Laboratory of Nanomaterials Synthesis and Biological Interactions (NanoBioss), Institute of Chemistry, Universidade Estadual de Campinas, Campinas, São Paulo 13083970, Brazil
3
Institute of Chemistry, Biological Chemistry Laboratory, Universidade Estadual de Campinas, Campinas, São Paulo 13083970, Brazil
4
Brazilian Nanotechnology National Laboratory (LNNano), CNPEM, Campinas, São Paulo 13083-970, Brazil
These authors contributed equally to this work.
*
Author to whom correspondence should be addressed.
Academic Editor: Nikolaos Michailidis
Received: 8 April 2015 / Revised: 18 May 2015 / Accepted: 26 May 2015 / Published: 3 June 2015
View Full-Text   |   Download PDF [1465 KB, uploaded 3 June 2015]   |  

Abstract

This review discusses recent advances in the synthesis, characterization and toxicity of metal oxide nanoparticles obtained mainly through biogenic (green) processes. The in vitro and in vivo toxicities of these oxides are discussed including a consideration of the factors important for safe use of these nanomaterials. The toxicities of different metal oxide nanoparticles are compared. The importance of biogenic synthesized metal oxide nanoparticles has been increasing in recent years; however, more studies aimed at better characterizing the potent toxicity of these nanoparticles are still necessary for nanosafely considerations and environmental perspectives. In this context, this review aims to inspire new research in the design of green approaches to obtain metal oxide nanoparticles for biomedical and technological applications and to highlight the critical need to fully investigate the nanotoxicity of these particles. View Full-Text
Keywords: nanotoxicity; metal oxide nanoparticles; biogenic nanoparticles; cytotoxicity; in vivo toxicity and ecotoxicity nanotoxicity; metal oxide nanoparticles; biogenic nanoparticles; cytotoxicity; in vivo toxicity and ecotoxicity
Figures

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Seabra, A.B.; Durán, N. Nanotoxicology of Metal Oxide Nanoparticles. Metals 2015, 5, 934-975.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Metals EISSN 2075-4701 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top