Precision Medicine in Vascular Disease

Dear Colleagues,

Over the last decades, evidence-based medicine (EBM) has emerged as a milestone for good clinical practice. Most recently, precision medicine (PM), which means the right medicine for the right patient at the right time, is overtaking the classic “one-size-fits-all” approach.

PM has been proposed as a new paradigm that supplements EBM rather than being in contrast with it. PM aims to consider the patient as an individual with specific characteristics within a predictive, preventive, personalized and participatory model. PM addresses each single patient, who often has comorbidities, with tailored indications, and can offer a valid solution. A patient with vascular disease, very often a comorbid condition, may benefit more than others from PM. Furthermore, PM is based on the observation that patients with apparently the same clinical diagnosis or symptoms often exhibit different responses to the same treatment. An increased understanding of the molecular and genetic mechanism of diseases and novel biomarkers can aid in selecting the patient who best benefits from a treatment.

In this Special Issue, we aim to publish a wide range of manuscripts on pathogenesis, diagnosis, genetics, omics and molecular study results, evaluation of biomarkers, predictive factors, potential therapies, indications for medical and surgical treatment in order to apply PM in the management of vascular diseases.

Dr. Gaetano Lanza
Prof. Dr. Carlo Setacci
Guest Editors

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• precision medicine
• vascular diseases
• pathogenetics
• diagnostics
• genetics
• omics
• biomarkers
• predictive factors
• medical therapies
• surgical indications