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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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DNA Damage, Oxidative Stress and Related Metabolic By-Products in Cancer and Environmental Studies 3.0
edited by
submission deadline 20 Jun 2024 | 1 articles | Viewed by 2572 | Submission Open
Keywords: DNA Damage; Oxidative Stress; By-Products
(This special issue belongs to the Section Molecular Toxicology)
Acute Radiation Syndrome and Therapies after Combined Radiation Injury
edited by
submission deadline 20 Jun 2024 | 1 articles | Viewed by 1873 | Submission Open
Keywords: radiation; wound; burn; hemorrhage; blast; fracture; chemical; infection; bone marrow; GI; spleen; brain; endothelium; skin
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Current Molecular Progress on Cell and Gene Therapies submission deadline 20 Jun 2024 | 1 articles | Viewed by 1753 | Submission Open
Keywords: gene therapy; cell therapy; gene delivery; gene editing; stem cells; regenerative medicine; CRISPR-Cas; viral vectors; non-viral vectors; immunotherapies
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Biological Biomarkers of Mild Traumatic Brain Injury
edited by and Damien Bouvier
submission deadline 20 Jun 2024 | 2 articles | Viewed by 1752 | Submission Open
Keywords: mild traumatic brain injury; blood biomarker; salivary biomarkers; micro-RNA; concussion; diagnosis; prognosis
(This special issue belongs to the Section Molecular Neurobiology)
Recent Perspectives on Oxidative Stress, Metabolic and Inflammatory Diseases submission deadline 20 Jun 2024 | 1 articles | Viewed by 1710 | Submission Open
Keywords: inflammation; oxidative stress; cytokines; mitochondria metabolic diseases
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Cancer-Related Biochemical Pathways: From Tumor Outgrowth, Metastasis to Novel Targeted Therapy
edited by
submission deadline 20 Jun 2024 | 1 articles | Viewed by 1637 | Submission Open
Keywords: oncogenesis; novel targeted therapy; molecular mechanisms; drug resistance; cancer cell death; amino acid metabolism
(This special issue belongs to the Section Molecular Oncology)
Advances in Research for Solanaceae Breeding and Genetics
edited by
submission deadline 20 Jun 2024 | 1 articles | Viewed by 1606 | Submission Open
Keywords: Solanaceae species; genomic approaches; mapping; new breeding techniques; genome editing
(This special issue belongs to the Section Molecular Plant Sciences)
Pulmonary Hypertension: Pre-clinical Research on New Molecular Targets and Therapeutic Strategies
edited by Pedro Mendes-Ferreira
submission deadline 20 Jun 2024 | 1 articles | Viewed by 1476 | Submission Open
Keywords: pulmonary hypertension; right ventricle; animal models; heart failure; pulmonary arterial hypertension
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Nanotechnology in Bone and Cartilage Repair and Regeneration
edited by
submission deadline 20 Jun 2024 | 1 articles | Viewed by 1455 | Submission Open
(This special issue belongs to the Section Molecular Nanoscience)
Molecular Researches on Ischemic Stroke 2.0
edited by
submission deadline 20 Jun 2024 | 1 articles | Viewed by 1442 | Submission Open
Keywords: ischemic stroke; molecular pathway; brain damage and neuronal death; excitotoxicity and apoptosis; inflammation; autophagy
(This special issue belongs to the Section Molecular Neurobiology)
Hydrogen Sulfide and H2S Donors in Cardiovascular, Metabolic, and Inflammatory Diseases submission deadline 20 Jun 2024 | 1 articles | Viewed by 1433 | Submission Open
Keywords: hydrogen sulfide; H2S-donors; cardiovascular diseases; metabolic diseases; inflammatory diseases; cancer; neurodegenerative diseases
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Role of Natural and Synthetic Sulfur Compounds in Human Health and Diseases
edited by
submission deadline 20 Jun 2024 | 1 articles | Viewed by 1425 | Submission Open
Keywords: sulfur compounds; sulfur metabolism; hydrogen sulfide; H2S-donors; human health; human disease; nutraceuticals
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Applicability of Graphene-Based Materials in the Pharmaceutical, Biological and Biomedical Sectors
edited by and Pogacean Florina
submission deadline 20 Jun 2024 | 2 articles | Viewed by 1308 | Submission Open
Keywords: graphene; graphene-based composites; graphene-based sensors; biomedical applications; tissue engineering; drug delivery
(This special issue belongs to the Section Molecular Nanoscience)
Immune Evasion and Pathological Prognostic Biomarkers in Bladder Cancer
edited by and
submission deadline 20 Jun 2024 | 1 articles | Viewed by 1275 | Submission Open
Keywords: bladder cancer; immune evasion; tumor microenvironment; tumor prognosis; immune checkpoint; immune tolerance
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Inflammatory and Immune Response to Helicobacter pylori Infection
edited by Leonid B. Lazebnik and
submission deadline 20 Jun 2024 | 1 articles | Viewed by 1245 | Submission Open
Keywords: adhesion; antibiotics resistance; bacteriophages; chronic inflammation; dysbiosis; eradication; fucosylated glycan; gastric cancer; gastric microbiota; gut microbiota; Helicobacter pylori; H. pylori-associated gastritis; H. pylori differ stamms; host immune response; inflammasome; inflammatory response; innate immunity; Lewis system antigens; matrix metalloproteinases; microbial interaction; microbial metabolites; microRNA; molecular mimicry; non-coding RNA; oxidative stress; pathogen-associated molecular patterns; pattern recognition receptors; phytochemicals; postbiotics; probiotics; synthetic peptides; vaccine; virulence factors
(This special issue belongs to the Section Molecular Microbiology)
Genetic Heterogeneity and Molecular Mechanism of Neurodevelopmental Disorders
edited by
submission deadline 20 Jun 2024 | 1 articles | Viewed by 1062 | Submission Open
Keywords: neurodevelopmental disorders; autism; intellectual disability; epilepsy; ADHD; behavioral disorder; next-generation sequencing; exome sequencing; genome sequencing; mouse; zebrafish; fruit fly; functional study; molecular diagnosis; genetics; genomics
(This special issue belongs to the Section Molecular Neurobiology)
Theoretical Approaches in Molecular Sciences
edited by
submission deadline 20 Jun 2024 | 1 articles | Viewed by 960 | Submission Open
(This special issue belongs to the Section Molecular Biology)
Molecular Mechanisms and Targeted Therapies of Breast Cancer
edited by , Karolina Jabłońska and
submission deadline 20 Jun 2024 | 3 articles | Viewed by 915 | Submission Open
Keywords: breast cancer; cancer progression; cancer metastasis; tumor microenvironment; molecular mechanisms; molecular markers; epigenetics; genomics; transcriptomics; EMT; targeted therapies; signaling pathways; exosomes; EMT; hormonal regulation; drugs; apoptosis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Luminescent Dyes as Tools for Biological and Medical Applications submission deadline 20 Jun 2024 | 1 articles | Viewed by 847 | Submission Open
Keywords: luminescence; biomedicine; biology; biosensing; bioimaging; nanostructures; small organic molecules; inorganic complexes
(This special issue belongs to the Section Biochemistry)
Advancements in Mast Cell Activation and Respiratory Conditions Updates submission deadline 20 Jun 2024 | 1 articles | Viewed by 826 | Submission Open
Keywords: mast cells; immune protection; inflammation; intestinal microbiota; genetic susceptibility; respiratory exacerbation; biomarkers; anaphylaxis; airway remodeling; biomass-burning smoke
(This special issue belongs to the Section Molecular Immunology)
Advanced Research in Molecular Modeling of Protein Structure and Functions
edited by Maria Khrenova
submission deadline 20 Jun 2024 | 1 articles | Viewed by 762 | Submission Open
Keywords: molecular modeling; QM/MM; molecular dynamics; DFT; enzymatic reactions; photoreceptor proteins; fluorescent proteins; substrate specificity; inhibition
(This special issue belongs to the Section Molecular Informatics)
Redox Enzymes of Bacteria and Parasites as Potential Drug Targets submission deadline 20 Jun 2024 | 1 articles | Viewed by 661 | Submission Open
Keywords: bacteria and parasite electron transport chains; membrane and cell wall component synthesis; dioxygenases; nitroreductases; antibacterial and antiparasitic agents
(This special issue belongs to the Section Biochemistry)
Advances in Cellular Immunotherapy for Hematological Malignancies
edited by Udo F. Hartwig
submission deadline 20 Jun 2024 | 1 articles | Viewed by 609 | Submission Open
Keywords: cellular immunity; T cell and NK cell immunology; oncoimmunology; cellular immunotherapy; cellular therapies to hematological malignancies; T cell and NK cell engineering; CAR T and NK cell therapy; bispecific T and NK cell antibodies
(This special issue belongs to the Section Molecular Immunology)
Single-Cell and Nano-Scale Analyses in Nanobiology: Unveiling the Structural Basis of Viruses, Microbes, and Intracellular Organelles
edited by
submission deadline 20 Jun 2024 | Viewed by 578 | Submission Open
Keywords: microbial systems; single-cell analysis; nano-scale analysis; phase separation; intracellular organization; genome folding; cell cycle; cytoskeleton; molecular imaging; analytical methods
(This special issue belongs to the Section Molecular Nanoscience)
Epigenetic Mediators Inducing Pathophysiological Changes in Cardiac Diseases
edited by
submission deadline 20 Jun 2024 | Viewed by 563 | Submission Open
Keywords: epigenetic mediators; cardiovascular diseases; molecular pathways
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Cell Metabolism: Its Physiology, Dysfunction, and Related Metabolic Complications
edited by
submission deadline 20 Jun 2024 | Viewed by 461 | Submission Open
Keywords: cell metabolism; adipocytes; muscle cells; hepatocytes; insulin resistance; inflammation; obesity; diabetes; hepatic disorders; cardiovascular diseases; cancers
(This special issue belongs to the Section Molecular Biology)
Advances in Proteomics in Cancer
edited by
submission deadline 20 Jun 2024 | Viewed by 459 | Submission Open
Keywords: cancer; proteomics; mass spectrometry; molecular targets; biomarker
(This special issue belongs to the Section Molecular Oncology)
RNA in Biology and Medicine
edited by Roberto Patarca and William A. Haseltine
submission deadline 20 Jun 2024 | 1 articles | Viewed by 457 | Submission Open
Keywords: noncoding RNAs; coding RNAs; RNA-based therapy; RNA vaccine; RNA structure; RNA function
(This special issue belongs to the Section Molecular Biology)
Molecular Advances in Musculoskeletal Disorders
edited by
submission deadline 20 Jun 2024 | Viewed by 400 | Submission Open
Keywords: osteoarthritis; osteoporosis; sarcopenia; tendinopathy; musculoskeletal pain
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
60th Anniversary from Indomethacin Approval: New Insights into the Mechanism of Action
edited by
submission deadline 20 Jun 2024 | Viewed by 368 | Submission Open
Keywords: anti-inflammatory; mechanism of action; NFR2; metabolism; immunity; aging; oxidative stress
(This special issue belongs to the Section Molecular Pharmacology)
Health Benefits of Catechins
edited by
submission deadline 20 Jun 2024 | Viewed by 351 | Submission Open
Keywords: catechins; diseases prevention; antioxidant; molecular mechanism; epicatechin
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Effect of Apolipoproteins on Infectious Diseases and Inflammatory Processes submission deadline 20 Jun 2024 | Viewed by 320 | Submission Open
Keywords: apolipoproteins; lipoproteins; intestinal microbiota; gut-liver axis; inflammation; cholesterol; toll-like receptors
(This special issue belongs to the Section Molecular Immunology)
Recent Research on Novel Lipid-Based Nano Drug Delivery Systems
edited by Eder Lilia Romero
submission deadline 20 Jun 2024 | Viewed by 280 | Submission Open
Keywords: lipids; nanoparticle; nanovesicle; algae; archaea; plant; bacteria; natural product
(This special issue belongs to the Section Molecular Pharmacology)
Epigenetic Modifications in Health and Disease
edited by Ravi Goyal
submission deadline 20 Jun 2024 | Viewed by 273 | Submission Open
Keywords: proximal promoter methylation; CpG islands; Dohad; fetal programming; fetal origins of adult disorders; developmental origins of health and disease
(This special issue belongs to the Section Molecular Genetics and Genomics)
Recent Advances on Bioreceptors and Nanomaterial-Based Biosensors submission deadline 20 Jun 2024 | Viewed by 266 | Submission Open
Keywords: biosensor; nanomaterials; microfluidic devices; mems; detection techniques; aptamers; antibodies
(This special issue belongs to the Section Biochemistry)
Molecular Mechanisms of Retinal Diseases: An Update
edited by
submission deadline 20 Jun 2024 | Viewed by 263 | Submission Open
Keywords: in vivo imaging; CRISPR/Cas9; iPS cells; single-cell RNA seq; age-related macular degeneration; diabetic retinopathy; inherited retinal diseases; glaucoma; myopia; retinal vascular diseases
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Oxidation and Inflammation in Human Health and Disease
edited by
submission deadline 20 Jun 2024 | Viewed by 248 | Submission Open
Keywords: oxidative stress; oxidative balance; biochemical markers; reactive oxygen species
(This special issue belongs to the Section Molecular Immunology)
New Insights into Oxidative Stress and Inflammation in Chronic Diseases
edited by Vlad Pădureanu
submission deadline 20 Jun 2024 | Viewed by 244 | Submission Open
Keywords: chronic diseases; inflammation; oxidative stress; acute pancreatitis; metabolic syndromes; antioxidants; sepsis; rheumatic disease; liver disease
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advanced Research in Biomolecular Design for Medical Applications
edited by
submission deadline 20 Jun 2024 | Viewed by 236 | Submission Open
Keywords: drug discovery; biomolecular design; molecular modeling; bioinformatics; medical applications
(This special issue belongs to the Section Molecular Informatics)
Molecular Research of Glycolysis 2.0 submission deadline 20 Jun 2024 | Viewed by 232 | Submission Open
Keywords: glycolysis; metabolic reprogramming; regulation; signaling transduction; metabolites; biosensors
(This special issue belongs to the Section Biochemistry)
New Advances in Glioma Knowledge: From Genome to Signal Pathways Alterations
edited by and Giuseppina D'Alessandro
submission deadline 20 Jun 2024 | Viewed by 227 | Submission Open
Keywords: gliomas; signalling pathways; genetic alterations; epigenetics; metabolic alterations; drug resistance; glioma stem cells
(This special issue belongs to the Section Molecular Neurobiology)
Stem Cells in Human Health and Diseases
edited by Dana Yehudai-Ofir
submission deadline 20 Jun 2024 | Viewed by 211 | Submission Open
Keywords: stem cells; stem cell biology; stem-cell-based therapy; stem cell regulation; cancer stem cell; tumor-initiating cell  
(This special issue belongs to the Section Molecular Immunology)
Bridging the Gap: Exploring the Link between Metabolic Disorders and Musculoskeletal Diseases
edited by
submission deadline 20 Jun 2024 | Viewed by 183 | Submission Open
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Roles of RNA (Coding and Non-coding) in Human Disease
edited by Lee Lee Wong
submission deadline 20 Jun 2024 | Viewed by 180 | Submission Open
Keywords: coding RNA; non-coding RNA; biomarker; functional role; therapeutic targets  
(This special issue belongs to the Section Macromolecules)
NRF2/KEAP1 Signalling in Cancer
edited by
submission deadline 20 Jun 2024 | Viewed by 159 | Submission Open
Keywords: oxidative stress; cancer; aging; senescence; inflammation; ovarian cancer; prostate cancer; antioxidants
(This special issue belongs to the Section Molecular Biology)
Advanced Research of Plant Secondary Metabolism 2.0 submission deadline 20 Jun 2024 | Viewed by 131 | Submission Open
Keywords: secondary metabolites; pathways; regulation; encapsulation; neofunctionalization; synthetic pathways; flavonoids; terpenoids; alkaloids
(This special issue belongs to the Section Molecular Plant Sciences)
Breast Cancer, Metastatic Breast Cancer, Therapeutic Approaches 2.0
edited by
submission deadline 21 Jun 2024 | 6 articles | Viewed by 6809 | Submission Open
Keywords: breast cancer; metastatic breast cancer; epithelial-to-mesenchymal transition (EMT); epigenetic and post-translational modifications (PTM); tumor microenvironment
(This special issue belongs to the Section Molecular Oncology)
Helicobacter pylori Extracellular Proteins and Cell Surface Structures: Towards Novel Therapeutics
edited by Terry Kwok
submission deadline 23 Jun 2024 | Viewed by 249 | Submission Open
Keywords: Helicobacter pylori; outer membrane protein; lipopolysaccharide; secreted soluble proteins; protease; antigenic diversity; adhesin; phase variation; gastric cancer
(This special issue belongs to the Section Molecular Microbiology)
TRP Channels in Physiology and Pathophysiology 2.0 submission deadline 25 Jun 2024 | 10 articles | Viewed by 10748 | Submission Open
Keywords: transient receptor potential (TRP) channels; retina; lens; lens epithelium; ion transport; homeostasis; ciliary body; ciliary epithelium; aqueous humor
(This special issue belongs to the Section Biochemistry)
Essential Molecules in Life: Regulation, Defense, and Longevity submission deadline 25 Jun 2024 | 5 articles | Viewed by 8535 | Submission Open
Keywords: glucose metabolism and its regulation; enzimology and kinetics; metabolism and evolution; cell growth; protein synthesis and degradation; cell proliferation and apoptosis; cancer; metastasis and angiogenesis; oxidative stress; genomic; proteomic and metab
(This special issue belongs to the Section Molecular Biology)
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