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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Mechanisms of Neuropsychiatric Diseases
edited by Dmitrii A. Pavlov
submission deadline 20 May 2024 | 1 articles | Viewed by 1610
Keywords: neurotransmitters; synaptic plasticity; epigenetics; genetic mutations; inflammation; oxidative stress; mitochondrial dysfunction; apoptosis; neuroinflammation; excitotoxicity; glutamate
(This special issue belongs to the Section Molecular Neurobiology)
Immunotherapy in Tumors: Treatments, Complications and Diagnostic Evaluation of Response
edited by
submission deadline 20 May 2024 | 1 articles | Viewed by 1526
Keywords: cancer immunotherapy; immune checkpoint inhibitor; complications; potential side-effects; immune response
(This special issue belongs to the Section Molecular Oncology)
Ubiquitin Receptors and Associated Mechanisms Involved in Targeting Proteins Modified with Diverged Ubiquitin Signals to Distinct Cellular Processes
edited by
submission deadline 20 May 2024 | 1 articles | Viewed by 1468
Keywords: ubiquitin; ubiquitin signals; ubiquitin binding; ubiquitin receptor; 26S proteasome; endocytosis; autophagy; epigenetic regulation; DNA repair
(This special issue belongs to the Section Molecular Plant Sciences)
Pathophysiology and Novel Therapeutic Strategies of Neurological Diseases
edited by
submission deadline 20 May 2024 | 1 articles | Viewed by 1465
Keywords: neurological disorders; neurogenetic diseases; pathophysiological mechanisms; mitochondrial diseases; spinal muscular atrophy; neurodegenerative diseases; treatment; therapeutics
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Role of MicroRNAs in Cancer Development and Treatment 2.0
edited by
submission deadline 20 May 2024 | 1 articles | Viewed by 1392
Keywords: microRNAs (miRNAs); transcriptomics; functional studies; cancer pathobiology; solid tumors; hematological malignancies; molecular biomarkers; therapeutic targets; apoptosis; anticancer drugs radiotherapy; chemotharapy failure
(This special issue belongs to the Section Molecular Oncology)
Multiplicity of Cerebrospinal Fluid Functions in Health and Disease
edited by
submission deadline 20 May 2024 | 1 articles | Viewed by 1338
Keywords: cerebrospinal fluid; choroid plexus; glymphatics; arachnoid; physiology; function; disease
(This special issue belongs to the Section Molecular Neurobiology)
The Role of Vitamin C in Human Health and Diseases submission deadline 20 May 2024 | 1 articles | Viewed by 1333
Keywords: vitamin C; vitamin C deficiency; vitamin C supplementation; recommended dose; immune system; health; disease; inflammation; cell metabolism; oxidative stress; pharmacokinetics; immunity
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Proteomics and Nanotechnology for Medical and Pharmacological Applications
edited by
submission deadline 20 May 2024 | 1 articles | Viewed by 1299
Keywords: biomolecules; peptides; proteomics; transcriptomics; nanotechnology; venomics
(This special issue belongs to the Section Molecular Pharmacology)
Natural Products and Neuroprotection 4.0 submission deadline 20 May 2024 | 1 articles | Viewed by 1253
Keywords: oxidative stress; inflammation; protein misfolding; natural compounds; nutraceuticals; phytochemicals neurodegeneration; Alzheimer’ s disease; Parkinson’ s disease; amyotrophic lateral sclerosis; multiple sclerosis; Huntington’ s disease
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Regulation of Ubiquitin Family Signaling in Disease 2.0
edited by
submission deadline 20 May 2024 | 1 articles | Viewed by 1211
Keywords: ubiquitin; SUMO; NEDD8; ISG15; FAT10; ubiquitin-like proteins; autophagy; proteasome
(This special issue belongs to the Section Molecular Biology)
Properties, Biosynthesis and Application of Antimicrobial Compounds submission deadline 20 May 2024 | 1 articles | Viewed by 1197
Keywords: antimicrobial compounds of microorganisms; whole genome sequencing; secondary metabolites; antimicrobial activity; biosynthesis; application
(This special issue belongs to the Section Molecular Microbiology)
Advances in Biofuels and Green Catalysts submission deadline 20 May 2024 | 1 articles | Viewed by 1188
Keywords: biofuels; green catalysts; enzymatic catalysis; renewable energy; catalytic mecanism; green chemistry; integrated biorefinery
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Recent Progress in Addition Reactions and Organic Synthesis
edited by
submission deadline 20 May 2024 | 1 articles | Viewed by 990
Keywords: addition reactions; organic synthesis; synthesis mechanism
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Drug Delivery Systems: Current Status in the Treatment of Human Diseases submission deadline 20 May 2024 | 1 articles | Viewed by 818
Keywords: human diseases; cancer; cardiovascular disease; biomaterials; drug delivery; targeted therapies; theranostics
(This special issue belongs to the Section Molecular Pharmacology)
Male Genitourinary Tumors: Molecular and Cellular Mechanism
edited by
submission deadline 20 May 2024 | 1 articles | Viewed by 782
Keywords: penile carcinoma; tumor biology; immune modulator; HPV   TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Cancer Suicide Gene Therapy
edited by
submission deadline 20 May 2024 | 1 articles | Viewed by 429
Keywords: directed enzyme prodrug therapy (DEPT); suicide gene therapy (SGT); gene-/virus-directed enzyme prodrug therapy (G-/V-DEPT); nitroreductase (NTR); hypoxia; transgene tracking
(This special issue belongs to the Section Molecular Oncology)
Cardiac Calcium Channels in Cardiovascular Function and Disease submission deadline 20 May 2024 | Viewed by 375
(This special issue belongs to the Section Biochemistry)
Recent Advances in Cystic Fibrosis: Pathophysiology, Molecular Mechanisms and Novel Therapies
edited by Virginia De Rose
submission deadline 20 May 2024 | Viewed by 374
Keywords: cystic fibrosis; pathophysiology; molecular pathways and mechanisms; novel therapies; CFTR modulators
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Advances and Perspectives in Multiple Sclerosis
edited by Joao Jose Cerqueira and
submission deadline 20 May 2024 | Viewed by 353
Keywords: astrocytes; axonal transection; demyelination; EBV; immunometabolism; insulin signaling; iron; lymphotoxin; microglia; mitochondria; neurodegeneration; oligodendrocytes; remyelination; brain barriers
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Recent Advances in Anti-microbial Biomaterials submission deadline 20 May 2024 | Viewed by 346
Keywords: SARS-CoV-2; microbial infections; biomaterials; antibacterial; antiviral; antifungal; microbial resisistance
(This special issue belongs to the Section Materials Science)
Nuclear Receptors in Health and Diseases 2.0
edited by
submission deadline 20 May 2024 | Viewed by 262
Keywords: nuclear receptors; hormone receptors; orphan receptors; retinoid receptors; PPARs; PXR; CAR; LXRs; FXR; RORs; RXRs; ERs; HNF4s; health; cancers; metabolic diseases; drug metabolism; agonists and antagonists; coactivators and corepressors
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Novel Molecular Research Targeting the Application of FFPE Tissue: Development and Updates
edited by William Mathieson
submission deadline 20 May 2024 | Viewed by 253
Keywords: FFPE tissue; genomic medicine; diagnosis; immunohistochemistry
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Mechanisms and Therapeutic Potential of Ion Channels in Human Diseases submission deadline 20 May 2024 | Viewed by 242
Keywords: ion channels; cancer; channelopathies; electrophysiology; patch clamp
(This special issue belongs to the Section Molecular Biology)
Cell Biology and Biochemistry Regulation Mediated by Natural Compounds
edited by
submission deadline 20 May 2024 | Viewed by 220
Keywords: cellular targets; natural compounds; nutraceuticals; health-promoting effects; enzymatic activity; cell-based assays; in vivo; nanoencapsulation; delivery of natural compounds
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Cancer: Molecular Research and Novel Inflammatory Targets submission deadline 20 May 2024 | Viewed by 159
Keywords: cancer; tumor microenvironment; molecular biology; biomarkers; novel and alternative therapies; inflammation; pharmacological inhibitors
(This special issue belongs to the Section Molecular Oncology)
Epigenetic Controls for Gene Panels in Oncology submission deadline 20 May 2024 | Viewed by 134
(This special issue belongs to the Section Molecular Genetics and Genomics)
The Role of Cytokines in Diseases submission deadline 22 May 2024 | 4 articles | Viewed by 2715 | Submission Open
Keywords: cytokines; inflammation; immune response; genetics; epigenetics; disease; infection; pathogen-associated molecular patterns; damage-associated molecular patterns; pattern-recognizing receptors; treatment
(This special issue belongs to the Section Biochemistry)
New Insights into Proteomics in Disease
edited by
submission deadline 24 May 2024 | 5 articles | Viewed by 7079 | Submission Open
Keywords: proteomics; disease biomarkers; data integration; bioinformatics; mass spectrometry; biochemical pathway; personalized medicine
(This special issue belongs to the Section Molecular Informatics)
Epilepsy: Molecular Mechanisms and Therapies submission deadline 24 May 2024 | 2 articles | Viewed by 4590 | Submission Open
Keywords: epilepsy; seizures; epileptogenesis; anticonvulsant drugs; ion channels; neurotransmitters; molecular mechanisms; epilepsy/seizure models
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Studies of Hematological Malignancies: Emphasis on Development of Flow-Cytometry and Cell-Sorting-Based Technics for Improving Diagnosis
edited by and Netanel A Horowitz
submission deadline 24 May 2024 | 1 articles | Viewed by 1284 | Submission Open
Keywords: laboratory hematology; hematological malignancies; flow cytometry and cell sorting; soluble biomarkers
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Non-coding RNAs' Functionality-Diagnosis and Therapy in Cancer and Other Indications submission deadline 25 May 2024 | 16 articles | Viewed by 28217 | Submission Open
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Novel Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression
edited by
submission deadline 25 May 2024 | 4 articles | Viewed by 10455 | Submission Open
Keywords: cancer; antineoplastic drugs; target therapy; drug delivery; computational studies; MDR; multitarget drugs
(This special issue belongs to the Section Molecular Pharmacology)
Circulating Cell-Free Nucleic Acids and Cancers 2.0
edited by
submission deadline 25 May 2024 | 6 articles | Viewed by 10439 | Submission Open
Keywords: biological fluids; cancer; cancer biomarkers; cfDI; cfDNA; cfNA; Copy number variation; ctDNA; ddPCR; disease-free survival; epigenetic; epigenetic sequencing; exosome; extracellular vesicle; genotyping; liquid biopsy; miRNA; mRNA; mutation; ncRNA; next-generation sequencing; overall survival; progression-free survival; recurrence-free survival; whole-exome sequencing
(This special issue belongs to the Section Molecular Oncology)
Fertility Preservation and Restoration Options with Female and Male Gonadal Tissue or Cells
edited by
submission deadline 25 May 2024 | 8 articles | Viewed by 9761 | Submission Open
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Molecular Aspects of Hematological Malignancies and Benign Hematological Disorders 2.0 submission deadline 25 May 2024 | 6 articles | Viewed by 9279 | Submission Open
Keywords: myeloproliferative neoplasms; leukemia; lymphoma; multiple myeloma; oxidative stress; inflammation; microbiome; genetics; molecular biology
(This special issue belongs to the Section Molecular Biology)
Biomaterials: From Design, Synthesis and Characterization to Application
edited by and
submission deadline 25 May 2024 | 5 articles | Viewed by 9207 | Submission Open
Keywords: biomaterials; synthesis; characterization; therapeutics; diagnosis
(This special issue belongs to the Section Materials Science)
Biomarkers in Rare Diseases 3.0
edited by
submission deadline 25 May 2024 | 5 articles | Viewed by 8435 | Submission Open
Keywords: orphan diseases; rare diseases; inborn errors of metabolism; mitochondrial disorders; biomarker discovery; biomarker panels; multiomics; endpoint measures
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Pathogenesis and Treatment of Skin Cancer submission deadline 25 May 2024 | 5 articles | Viewed by 7160 | Submission Open
Keywords: melanoma; squamous cell carcinoma; basal cell carcinoma; tumor microenvironment; epithelial– mesenchymal transition (EMT) process; ultraviolet radiation; oxidative stress; bioactive modulators; signal transduction pathways
(This special issue belongs to the Section Molecular Oncology)
Recent Molecular Research of Parkinson's Disease submission deadline 25 May 2024 | 4 articles | Viewed by 6377 | Submission Open
Keywords: aging; alpha-synuclein; autophagy; body-first Parkinson’ s disease; brain-first Parkinson’ s disease; clinical neuroscience; familial Parkinson’ s disease (fPD); iron; intestinal microbe; intracellular proteolysis; Lewy bodies; mitochondrial dysfunction; neuromelanin; neuropsychiatry; oxidative stress
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Research of Regulation of Red Blood Cells in Health, Hereditary or Acquired Diseases submission deadline 25 May 2024 | 5 articles | Viewed by 5765 | Submission Open
Keywords: red blood cells; erythropoiesis; oxygen carrier; hemoglobin; thalassemia; sickle cell disease; dyserythropoiesis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Current Insights on Neuroprotection submission deadline 25 May 2024 | 2 articles | Viewed by 5122 | Submission Open
Keywords: neuronal structure; neuronal function; neuroprotection; secondary injuries; oxygen; glucose; oxidative stress; mitochondrial dysfunction; inflammation; excitotoxicity
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Mechanisms and Novel Therapies of Liver Diseases
edited by
submission deadline 25 May 2024 | 2 articles | Viewed by 2378 | Submission Open
Keywords: acute and chronic liver diseases (CLDs); hepatocellular carcinoma (HCC); post-translational modification (PTM); autophagy; potential therapeutic approaches; preclinical mouse models  
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Permeation Enhancers and Other Strategies to Overcome Skin and Mucosal Barriers submission deadline 25 May 2024 | 1 articles | Viewed by 2043 | Submission Open
Keywords: permeation enhancer; physical permeation enhancers; ultrasounds; iontophoresis; electroporation; microneedles; nanoparticles; nanocarriers; liposomes; lipid-based nanostructured systems
(This special issue belongs to the Section Molecular Pharmacology)
Research Advances in Neurodegeneration and Neuropathy
edited by
submission deadline 25 May 2024 | 1 articles | Viewed by 1596 | Submission Open
Keywords: mechanism; neurodegenerative disease; neuropathy
(This special issue belongs to the Section Molecular Neurobiology)
New Avenues in Molecular Docking for Drug Design 2023
edited by
submission deadline 25 May 2024 | 1 articles | Viewed by 1528 | Submission Open
Keywords: structure-based drug design; molecular targets; molecular recognition; ligand binding; virtual screening; drug repositioning; multi-target ligands; scoring function; pose generation and evaluation; big data
(This special issue belongs to the Section Molecular Informatics)
Roles of Inflammasomes in Inflammatory Responses and Human Diseases
edited by
submission deadline 25 May 2024 | 1 articles | Viewed by 1378 | Submission Open
Keywords: inflammasome; inflammatory responses; human diseases; anti-inflammatory therapeutics
(This special issue belongs to the Section Molecular Immunology)
Molecular Mechanisms of Pain and Analgesia
edited by and Hee Young Kim
submission deadline 25 May 2024 | 1 articles | Viewed by 1065 | Submission Open
Keywords: pain; analgesia; sensory transmission and integration; molecular pathways; pain genes; drug targets
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Structure–Function Investigations of Viruses
edited by
submission deadline 25 May 2024 | 1 articles | Viewed by 883 | Submission Open
Keywords: structure; assembly; viruses; crystallography; spectroscopy; computer modeling
(This special issue belongs to the Section Molecular Biophysics)
Animal and Plant Cell–Tissue, Organ Specialization and Function: Investigational, Experimental and Medical Aspects, 4th Edition submission deadline 25 May 2024 | 2 articles | Viewed by 813 | Submission Open
Keywords: plant and animal cell; ultrastructure; cell biology; cell development; cell regeneration; cell signaling; tissue histology; tissue physiology and pathology; environmental effects; toxicology
(This special issue belongs to the Section Biochemistry)
Advances in Research on Fruit Crop Breeding and Genetics 3.0 submission deadline 25 May 2024 | 1 articles | Viewed by 760 | Submission Open
Keywords: fruit breeding; genetic; genomic; transcriptomic; proteomic; epigenetic
(This special issue belongs to the Section Molecular Plant Sciences)
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