Special Issues

Biomolecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Cancer Therapy Resistance
edited by
submission deadline 30 Jun 2024 | 1 articles | Viewed by 2534 | Submission Open
Keywords: cancer therapy resistance; genetic mutations in drug resistance; tumor microenvironment and therapy resistance; epigenetic mediators in drug resistance; cell signaling pathways in therapy failure; combination therapies
(This special issue belongs to the Section Molecular Medicine)
Neuroimmune Interactions in Neuropsychiatric Diseases
edited by
submission deadline 30 Jun 2024 | 1 articles | Viewed by 2272 | Submission Open
Keywords: neurology; psychiatry; immunity; glia
(This special issue belongs to the Section Molecular Biology)
The Structure and Function of Proteins, Lipids and Nucleic Acids
edited by
submission deadline 30 Jun 2024 | 1 articles | Viewed by 2237 | Submission Open
(This special issue belongs to the Section Molecular Structure and Dynamics)
Amyloid-Beta (Aβ) Production/Clearance Balance and Aβ Neurotoxicity in Alzheimer’s Disease: From Mechanisms to Therapy submission deadline 30 Jun 2024 | 2 articles | Viewed by 2077 | Submission Open
Keywords: Alzheimer's disease; amyloid-beta (Aβ ); neurotoxicity of Aβ ; Aβ phagocytosis; Aβ clearance; autophagy-lysosome system; anti-Aβ monoclonal antibodies; catalytides
(This special issue belongs to the Section Cellular Biochemistry)
Vascular Disease and Thrombosis
edited by
submission deadline 30 Jun 2024 | 1 articles | Viewed by 1792 | Submission Open
Keywords: venous thromboembolism; superficial vein thrombosis; deep vein thrombosis; pulmonary embolism; post-thrombotic syndrome; ischemic heart disease; acute myocardial infarction; ischemic stroke; acute limb ischemia; intestinal infarction; biomarkers; hematologic disorders; thrombophilias
(This special issue belongs to the Section Molecular Medicine)
The Evolution and Function of Repetitive DNA
edited by Raquel Chaves and Sandra Louzada
submission deadline 30 Jun 2024 | 1 articles | Viewed by 1668 | Submission Open
Keywords: repetitive DNA; satellite DNA; transposable elements; non-coding RNA transcripts; evolution of repetitive DNA; genome instability; genome evolution
(This special issue belongs to the Section Molecular Biology)
The Role of Vascular Dysfunction in Neuronal Degeneration and Cognitive Impairment 2.0
edited by
submission deadline 30 Jun 2024 | 1 articles | Viewed by 1324 | Submission Open
Keywords: blood cells; plasma components; vascular wall components; neurovascular unit; neuroinflammation; cognitive decline
(This special issue belongs to the Section Molecular Biology)
The Role of Amyloid in Neurological Disorders
edited by and Tamara Berno
submission deadline 30 Jun 2024 | 1 articles | Viewed by 1265 | Submission Open
Keywords: amyloid-beta; neurodegenerative disorders; aducanumab; oligomers; cross-amyloid intraction
(This special issue belongs to the Section Biomacromolecules: Proteins)
Honorary Special Issue Dedicated to Prof. Giovanni Targher–the Metabolic Fatty Liver Syndromes: MASLD/MAFLD/NAFLD submission deadline 30 Jun 2024 | 1 articles | Viewed by 1166 | Submission Open
Keywords: nonalcoholic fatty liver disease (NAFLD); metabolic associated fatty liver disease (MAFLD); nonalcoholic steatohepatitis (NASH); metabolic dysfunction-associated steatotic liver disease (MASLD); fatty liver
(This special issue belongs to the Section Biomacromolecules: Lipids)
Biomolecules and Their Impact on Biology and Translational Applications: Celebrating the Pioneering Work of Prof. Ho Jeong Kwon
edited by and Hye Jin Kang
submission deadline 30 Jun 2024 | 1 articles | Viewed by 1133 | Submission Open
Keywords: biomolecules; cancer; angiogenesis; autophagy; GPCRs; translational applications; target identification; proximity-labeling; molecular docking; molecular probe; molecular pharmacology
(This special issue belongs to the Section Cellular Biochemistry)
New Insights into Cardiometabolic Diseases submission deadline 30 Jun 2024 | Viewed by 773 | Submission Open
Keywords: metabolic diseases; hypertension; obesity; type-2 diabetes; vascular diseases; acute vascular events
(This special issue belongs to the Section Molecular Medicine)
Role of TRAF1 in Regulating Inflammation and Cell Survival
edited by Ali Abdul-Sater
submission deadline 30 Jun 2024 | 1 articles | Viewed by 681 | Submission Open
Keywords: TRAF1; inflammation; inflammasome; TNFRs; apoptosis; cellular survival
(This special issue belongs to the Section Biological Factors)
Research into Bioactive Natural Compounds: New Molecules, Bioinspired Syntheses, Biotechnological Methods and Bioassays—Celebrating the Pioneering Work of Prof. Alejandro Fernandez Barrero submission deadline 30 Jun 2024 | Viewed by 339 | Submission Open
Keywords: natural products; bioactivity; organic synthesis; biotecnnology; structural elucidation
(This special issue belongs to the Section Natural and Bio-inspired Molecules)
Advances in CRISPR/Cas Systems for Genome Editing Applications in Biomedical Research
edited by
submission deadline 30 Jun 2024 | Viewed by 233 | Submission Open
Keywords: genome editing; CRISPR/Cas; gene therapy; cancer immunotherapy; diagnosis
(This special issue belongs to the Section Molecular Biology)
Nutritional Deficiencies as a Driver of Inflammation: Molecular Mechanisms of Immune Defense submission deadline 30 Jun 2024 | Viewed by 233 | Submission Open
Keywords: nutritional deficiencies; nutrients; minerals; cross feeding; microbes; inflammation; immune resilience; immune tolerance
(This special issue belongs to the Section Biological Factors)
Molecular Basis of Stress- and Trauma-Related Disorders
edited by Vanessa Nieratschker
submission deadline 30 Jun 2024 | Viewed by 204 | Submission Open
Keywords: stress; trauma; epigenetics; genetics; molecular mechanisms; transgenerational transmission; neuronal adaptations; transcriptomics; proteomics; metabolomics
(This special issue belongs to the Section Molecular Medicine)
Homocysteine and H2S in Health and Disease submission deadline 30 Jun 2024 | Viewed by 203 | Submission Open
Keywords: homocysteine (Hcy); hydrogen sulfide (H2S); oxidative stress; inflammation
(This special issue belongs to the Section Chemical Biology)
The Role of Extracellular Matrix, Cell Membrane and Nuclear Involvement in Cellular Driven Mechanotransduction submission deadline 30 Jun 2024 | Viewed by 194 | Submission Open
Keywords: cell membrane; cytosol; nuclear membrane; integrin; mechanotransduction; map kinase pathway; ERKs; JNKs; p38/SAPKs; YAP/TAZ; Hippo pathway
(This special issue belongs to the Section Cellular Biochemistry)
The Role of Telomeres and Telomerase in Aging
edited by
submission deadline 30 Jun 2024 | Viewed by 184 | Submission Open
(This special issue belongs to the Section Cellular Biochemistry)
Epigenetics of Pulmonary Diseases submission deadline 30 Jun 2024 | Viewed by 180 | Submission Open
Keywords: asthma; mucus; chronic obstructive pulmonary disease; interstitial lung diseases; pulmonary arterial hypertension; acute lung injury; lung tuberculosis; pulmonary embolism; covalent modification; oxidative stress; DNA methylation; histone modification; noncoding RNAs; epigenetic regulation
(This special issue belongs to the Section Molecular Medicine)
Therapeutic Strategies via Skeletal and Mesenchymal Stem Cells in the Cranial and Dental Fields submission deadline 30 Jun 2024 | Viewed by 176 | Submission Open
Keywords: mesenchymal stem cells; tissue engineering; regenerative therapy
(This special issue belongs to the Section Molecular Medicine)
Human Reproductive Biology: Uncertainties and Controversies
edited by , and Paola Bianchi
submission deadline 30 Jun 2024 | Viewed by 165 | Submission Open
Keywords: molecular reproduction; endometriosis; endometrium; implantation; decidualization; placenta; cellular senescence; prostaglandin; inflammation; pregnancy; reproduction; implantation; decidualization; endometriosis; assisted reproductive technology; molecular reproductive biology; reproductive biology; reproductive immunology; reproductive medicine; reproductive endocrinology; molecular regulation of reproductive processes; embryo development; reproductive biology; gametogenesis and fertilization
(This special issue belongs to the Section Molecular Reproduction)
Molecular Diagnosis and Regulation of Mitochondrial Dysfunction
edited by
submission deadline 30 Jun 2024 | Viewed by 150 | Submission Open
Keywords: metabolic conditions; neurological conditions; genetic diseases; mitochondrial dysfunction; mitochondrial disorders; diagnostics; therapies
The Role of MDM2 in Tumor Biology and Cancer Therapy submission deadline 30 Jun 2024 | Viewed by 140 | Submission Open
Keywords: MDM2; p53; targeted therapy; imunotherapy; drug resistance
(This special issue belongs to the Section Molecular Genetics)
Sphingomonas: Metabolism and Use in Biotransformation of Biomolecules submission deadline 30 Jun 2024 | Viewed by 132 | Submission Open
Keywords: Sphingomonas; bioremediation; polycyclic aromatic hydrocarbons; pesticides; organophosphates; polysaccharides; lignin; value-added compounds; microbial cell factories; gene engineering; synthetic biology; gene expression systems; mathematical modelling
Epstein-Barr Virus Disease Mechanisms and Stress Responses II submission deadline 30 Jun 2024 | Viewed by 126 | Submission Open
Keywords: Epstein– Barr virus (EBV); reactivation; immune modulation; stress; aging
(This special issue belongs to the Section Molecular Medicine)
Human Gut Microbiome and Diet in Health and Diseases II
edited by
submission deadline 30 Jun 2024 | Viewed by 111 | Submission Open
Keywords: gut microbiome; microbiota; nutrition; functional foods; mucosal immunity; dysbiosis
The Role of Glia in Alzheimer's Disease
edited by
submission deadline 30 Jun 2024 | Viewed by 111 | Submission Open
Keywords: Alzheimer's disease; neurodegeneration; glial cells
(This special issue belongs to the Section Molecular Medicine)
Prebiotics and Probiotics in Health and Disease: Looking at the Future submission deadline 1 Jul 2024 | Viewed by 235 | Submission Open
Keywords: probiotics; live biotherapeutic product (LBP); next-generation probiotic (NGP); prebiotic; synbiotic/symbiotic; pharmabiotics; post-biotics; paraprobiotic/ghost probiotics/inactivated probiotics; probioceuticals/probiotaceuticals; biogenic; gut balance; gut– brain axis; vaginal homeostasis; vaginal microbiota modification or augmentation; oral microbiota; skin microbiota; new therapeutic approaches using bacteria; psychobiotics
New Advances of Cannabinoid Receptors in Health and Disease submission deadline 15 Jul 2024 | 6 articles | Viewed by 15745 | Submission Open
Keywords: neurodegeneration; alcohol; addiction; signaling; structure– function
(This special issue belongs to the Section Molecular Biology)
Novel Materials for Biomedical Applications II submission deadline 15 Jul 2024 | 6 articles | Viewed by 10282 | Submission Open
Keywords: micro-/nanocarriers; synthesis or conjugation of biomaterials; drug delivery; targeted therapy/immunotherapy for combinatorial treatment; regenerative medicine/tissue engineering
(This special issue belongs to the Section Biological and Bio- Materials)
Learn from Machine Learning: The Identification of Biomarkers and Therapeutic Targets in Neurodegeneration
edited by and
submission deadline 15 Jul 2024 | 2 articles | Viewed by 3402 | Submission Open
Keywords: machine learning; neurodegeneration; biomarkers; therapeutic targets; data mining
(This special issue belongs to the Section Molecular Medicine)
Circular RNAs: Functions, Applications and Prospects II
edited by and Feiya Li
submission deadline 15 Jul 2024 | 2 articles | Viewed by 2542 | Submission Open
Keywords: circular RNAs; circRNA; function; application; disease
(This special issue belongs to the Section Biomacromolecules: Nucleic Acids)
New Insights into Neuroimmunology submission deadline 15 Jul 2024 | 1 articles | Viewed by 1596 | Submission Open
Keywords: neuroimmunology (in health and disease); multiple sclerosis (MS); experimental autoimmune encephalomyelitis (EAE); acute disseminated encephalomyelitis (ADEM); neuromyelitis optica spectrum disorders (NMOSD); transverse myelitis; anti-NMDA receptor encephalitis (NMDAR encephalitis); paraneoplastic autoimmune diseases; neurodegenerative diseases with immunological components; Parkinson’ s disease; Alzheimer’ s disease; neuroinfections
(This special issue belongs to the Section Cellular Biochemistry)
Molecular Mechanisms of Human Skin Aging
edited by
submission deadline 15 Jul 2024 | 1 articles | Viewed by 1411 | Submission Open
Keywords: skin aging; UV; extracellular matrix; fibroblast; prevention
Transglutaminases: Regulation, Imaging, and Applications
edited by Thomas M. Jeitner
submission deadline 15 Jul 2024 | 1 articles | Viewed by 900 | Submission Open
Keywords: imaging; regulation; application; clinical translation
(This special issue belongs to the Section Enzymology)
Conventional and In Silico-Based Approaches for the Optimization of Nanobody Biophysical Characteristics
edited by
submission deadline 15 Jul 2024 | 1 articles | Viewed by 389 | Submission Open
Keywords: nanobodies; modeling; screening strategies; random mutagenesis; rational engineering; expression conditions
Molecular Insights into the Mechanism of Antipsychotic Drugs
edited by Serdar Dursun and
submission deadline 15 Jul 2024 | Viewed by 256 | Submission Open
Keywords: psychotropic medications; antipsychotic drugs; schizophrenia; molecular mechanisms
Skeletal Muscle in Health, Exercise and Aging
edited by Barbara Munz
submission deadline 15 Jul 2024 | Viewed by 182 | Submission Open
Keywords: skeletal muscle; molecular mechanisms of exercise adaptation; aging; cachexia; sarcopenia
(This special issue belongs to the Section Molecular Biology)
Pathogenesis and Therapies of SARS-CoV-2
edited by and Piotr Kopiński
submission deadline 15 Jul 2024 | Viewed by 121 | Submission Open
Keywords: ARDS in COVID-19; COVID-19 therapies; COVID-19 vaccines; immune systems in COVID-19; long-COVID pathogenesis; SARS-Cov-2 genomics; SARS-Cov-2 variants; T-cells in COVID-19
Complex Muscle Models
edited by Sonia Albini
submission deadline 15 Jul 2024 | Viewed by 110 | Submission Open
Keywords: muscular dystrophy; skeletal muscle; cardiac muscle; bioengineering; biomechanics; humanized models; pathophysiological; screening platform
(This special issue belongs to the Section Molecular Biology)
PARPs in Cell Death and PARP Inhibitors in Cancers submission deadline 20 Jul 2024 | 1 articles | Viewed by 2068 | Submission Open
Keywords: PARPs; PARP inhibitors; cancers; cell death; DNA repair
(This special issue belongs to the Section Molecular Medicine)
Advances in tRNA Biology
edited by
submission deadline 20 Jul 2024 | 1 articles | Viewed by 1679 | Submission Open
(This special issue belongs to the Section Biomacromolecules: Nucleic Acids)
Human Epidermal Stem Cells: Molecular Identifiers and Functional Regulators submission deadline 20 Jul 2024 | Viewed by 191 | Submission Open
Keywords: human epidermis; stem cells; intrinsic characters; dialogues; exposome
(This special issue belongs to the Section Molecular Biology)
Genetics and Genomics of Leukaemia
edited by and
submission deadline 23 Jul 2024 | Viewed by 544 | Submission Open
Keywords: leukaemia; blood; genetics; genomics; chromosome
(This special issue belongs to the Section Molecular Genetics)
Unraveling the Complexity of the Human Spliceosome and RNA Splicing
edited by Liliana Florea
submission deadline 30 Jul 2024 | Viewed by 174 | Submission Open
Keywords: spliceosome; splicing regulation; RNA splicing in human physiology and development; computational modelling
(This special issue belongs to the Section Biomacromolecules: Nucleic Acids)
Stress, Aging and Metabolism
edited by
submission deadline 31 Jul 2024 | 3 articles | Viewed by 8938 | Submission Open
Keywords: DNA damage; oxidative stress; aging; lifespan; healthspan; metabolism; stress-induced molecules and their functions; autophagy; exercise; nutritional restriction
(This special issue belongs to the Section Molecular Medicine)
The Role of Tumor Microenvironment in the Pathogenesis and Progression of Hematological Malignancies
edited by
submission deadline 31 Jul 2024 | 3 articles | Viewed by 6365 | Submission Open
Keywords: inflammation; metabolic rewiring; epigenetics; mesenchymal stromal cells; immune cells; immune-escape
(This special issue belongs to the Section Molecular Medicine)
Defects in the Transport Mechanism of Membrane Proteins and Related Diseases submission deadline 31 Jul 2024 | 3 articles | Viewed by 5841 | Submission Open
Keywords: function; structure and folding of membrane transport proteins; pathological mutations; mechanism of transport; neurological and metabolic disease; transport of nanoparticles; organelle membranes; cellular function and signaling; bioenergetics; neuroinflammation; nanoformulations for drug targets
(This special issue belongs to the Section Cellular Biochemistry)
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