Molecular Profiling and Identification of Molecular Signatures Associated with Tissue Development, Tumorigenesis, and Anticancer Agents’ Action

Dear Colleagues,

During tissue development or tumorigenesis, changes in the mechanisms of transcriptional regulation induce molecular reprogramming, leading to differential gene expressions. Molecular profiling, such as transcriptomics and proteomics, has expanded the knowledge of the repertoire of the transcribed genes specifically inherent to either developing or transformed model systems, thereby allowing the identification and classification of sets of molecular signatures. The individuation of single or panels of novel expression markers has provided a broader picture of the numerous and complex aspects associated with the development of body structures and the molecular pathogenesis of diverse malignancies, also aiding in the dissection of the mode of action of anticancer agents and thereby yielding potentially clinically relevant diagnostic and prognostic information. We are pleased to invite you to contribute original research articles and reviews focused on the identification of molecular biomarkers associated with the building of tissue structures or the progression of cancer, which might also unveil novel routes of signal transduction and cell metabolism, including the molecular profilings associated with antitumoral agents. We look forward to receiving your contributions.

Prof. Dr. Claudio Luparello
Dr. Rita Ferreira
Topic Editors