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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Obesity and Malignancies in Women: Searching for New Molecular Links
edited by
submission deadline 29 May 2024 | Viewed by 224
Keywords: obesity; female malignancies; adipokines; tumor microenvironment
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Fate of Pancreatic Islets in Type 2 Diabetes—2nd Edition submission deadline 29 May 2024 | Viewed by 218
Keywords: pancreatic β -cell; dedifferentiation; apoptosis; proliferation; neogenesis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Current Advances in Antivirals and Vaccines
edited by
submission deadline 29 May 2024 | Viewed by 196
Keywords: disease prevention; pandemic control; treatment of existing infections; antiviral resistance; global health equity; herd immunity; preparedness for emerging threats
(This special issue belongs to the Section Molecular Microbiology)
Antimicrobial Biomaterials: Recent Progress
edited by
submission deadline 30 May 2024 | 15 articles | Viewed by 32764 | Submission Open
Keywords: antimicrobial agents; chemical modification; polymer engineering; polymer synthesis; surface functionalization; antimicrobial agents immobilization; new drug delivery systems; microbiocidal; infection control
(This special issue belongs to the Section Materials Science)
Oxidative Stress in Metabolic and Endocrine Diseases: Basic and Translational Aspects 3.0 submission deadline 30 May 2024 | 4 articles | Viewed by 17827 | Submission Open
Keywords: antioxidants; radical species; nutraceutics; metabolic syndrome; endocrine glands; hormone metabolism; inflammation in endocrine disorders
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Medicinal Plants and Natural Compounds in Health and Disease: Progresses, Challenges, Opportunities submission deadline 30 May 2024 | 12 articles | Viewed by 16988 | Submission Open
Keywords: medicinal plants; phytochemicals; vitamins; oxidative stress; gene expression; protein expression; cellular signaling; ethnopharmacology
(This special issue belongs to the Section Molecular Pharmacology)
Sepsis and Septic Shock: From Molecular Mechanisms to Novel Therapies
edited by and Michael Adamzik
submission deadline 30 May 2024 | 12 articles | Viewed by 16873 | Submission Open
Keywords: sepsis; septic shock; mechanistic insight; epigenetics; immunometabolism; biomarkers; therapy approach; stratification; precision diagnostics
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Role of Biostimulants in Stimulating Plant Productivity submission deadline 30 May 2024 | 4 articles | Viewed by 15168 | Submission Open
Keywords: biostimulants; bioactivity; crop nutrition; abiotic stress; humic substances; beneficial microorganisms; beneficial elements
(This special issue belongs to the Section Molecular Plant Sciences)
Materials for Photobiology 2.0 submission deadline 30 May 2024 | 10 articles | Viewed by 14329 | Submission Open
Keywords: light-responsive materials; phototherapeutics; photodiagnosis; bioimaging; living bioluminescent materials; light-induced therapy; UV-radiation effect; photo-antinfective materials; photosensory biology; molecular optogenetics
(This special issue belongs to the Section Materials Science)
Health Benefits of Curcumin submission deadline 30 May 2024 | 5 articles | Viewed by 13572 | Submission Open
Keywords: curcumin; molecular mechanism; anti-tumor; health; therapies; polyphenol
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Technological and Molecular Advances in Systemic Lupus Erythematosus
edited by
submission deadline 30 May 2024 | 6 articles | Viewed by 13450 | Submission Open
Keywords: Systemic Lupus Erythematosus; SLE; autoreactive lymphocytes; antoantibodies; lupus nephritis; immunological heterogeneous; genomics; proteomics; metabolomics; biomarkers; cellular and molecular therapies; stem cell transplantation; CAR-T cell therapies; biologic therapy; imaging diagnosis; treatment strategies
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
New Trends in Diabetes, Hypertension and Cardiovascular Diseases 2.0 submission deadline 30 May 2024 | 6 articles | Viewed by 12012 | Submission Open
Keywords: cardiovascular disease; myocardial infarction; stroke; transient ischaemic attack; hypertension; diabetes mellitus; atherosclerosis; inflammation
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Studies of Dermatitis: From Mechanism to Therapy
edited by
submission deadline 30 May 2024 | 7 articles | Viewed by 11975 | Submission Open
Keywords: dermatitis; the innate immune system; cytokine
(This special issue belongs to the Section Molecular Immunology)
The Role of Carotenoids in Health and Disease
edited by and Lowell D. Kispert
submission deadline 30 May 2024 | 6 articles | Viewed by 11315 | Submission Open
Keywords: carotenoids; antioxidant activity; free radicals; supramolecular complexes; health benefit; eye and other diseases  
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Antioxidants and Anti-inflammatory, Antiproliferative Activities of Natural Products
edited by Bruno Eto
submission deadline 30 May 2024 | 10 articles | Viewed by 10727 | Submission Open
Keywords: bioactive products; anti-infectives; antioxidants; anti-inflammatory; antiproliferative; clinical phytopharmacology; phytopharmacology; polyphytotherapy
(This special issue belongs to the Section Bioactives and Nutraceuticals)
mTOR Signaling: Recent Progress submission deadline 30 May 2024 | 7 articles | Viewed by 10722 | Submission Open
Keywords: mTOR signaling in cancer; mTOR inhibitors; mTOR signaling in metabolism; Alzheimer’ s disease and mTOR signaling; mTOR and autophagy; mTOR and gut microbiota; mTOR and viral pathogenesis; mTOR and autoimmune diseases
(This special issue belongs to the Section Molecular Biology)
Challenges and Innovation in Neurodegenerative Diseases
edited by
submission deadline 30 May 2024 | 7 articles | Viewed by 9524 | Submission Open
Keywords: neurodegenerative diseases; pathogenesis; biomarkers; disease model; natural product; new drug discovery; therapy; machine learning; stem cell therapy
(This special issue belongs to the Section Molecular Neurobiology)
Transglutaminase 2 and Cellular Functions submission deadline 30 May 2024 | 7 articles | Viewed by 9386 | Submission Open
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Insights in Reproductive Immunology and Placental Pathology
edited by
submission deadline 30 May 2024 | 8 articles | Viewed by 9300 | Submission Open
Keywords: gamete immunology; in vitro fertilization; infertility; immunocontraception; implantation; placentation; immunotolerance; reproductive immunology; inflammation; cytokine network; placenta-derived stem cells; placental development; placental insufficiency; endometriosis; immunopathology of pregnancy; sex hormones
(This special issue belongs to the Section Molecular Immunology)
Metallodrugs: Mechanisms of Action, Molecular Targets and Biological Activity 2.0 submission deadline 30 May 2024 | 5 articles | Viewed by 9250 | Submission Open
Keywords: metal-based drugs; protein metalation; coordination chemistry; metal binding sites; organometallic compounds
(This special issue belongs to the Section Biochemistry)
Alzheimer’s Disease: From Pathogenesis to Treatment
edited by
submission deadline 30 May 2024 | 7 articles | Viewed by 9147 | Submission Open
Keywords: Alzheimer’ s disease; neurodegeneration; neurotransmitter; Aβ ; Tau; neuroinflammation; behavioral symptoms; symptomatic treatment; DMT
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Mechanisms of mRNA Transcriptional Regulation: 2nd Edition submission deadline 30 May 2024 | 5 articles | Viewed by 8525 | Submission Open
Keywords: transcriptoion factors (TFs); cis-regulatory elements (CREs); long non-coding RNAs (lncRNAs); short non-coding RNAs (sncRNAs); small nuclear RNAs (snRNAs); microRNA (miRNA); circular RNA (circRNA); DNA methylation; chromatin regulators
(This special issue belongs to the Section Biochemistry)
Plant Defense Response to Microbial, Herbivorous, and Environmental Interactions
edited by
submission deadline 30 May 2024 | 4 articles | Viewed by 8513 | Submission Open
Keywords: plant pathogenic infections; insect pest damage; abiotic stress; plant/microbial chemical signaling; innate immunity; systemic acquired resistance (SAR); pathogen-related proteins; plant defense enzymes; plant growth hormones
(This special issue belongs to the Section Molecular Plant Sciences)
Cell Biology in Diabetes and Diabetic Complications submission deadline 30 May 2024 | 4 articles | Viewed by 8484 | Submission Open
Keywords: diabetes; obesity; insulin resistance; hypertension; diabetic nephropathy
(This special issue belongs to the Section Molecular Biology)
Amyotrophic Lateral Sclerosis as a Systemic Disease 2.0
edited by
submission deadline 30 May 2024 | 4 articles | Viewed by 8406 | Submission Open
Keywords: neurogenic muscle atrophy; retrograde signals; crosstalk; multi-system biomarkers; neuroinflammation; neurodegeneration; hypermetabolism
(This special issue belongs to the Section Molecular Neurobiology)
Bioactive Lipids: From the Perspective of Cellular and Molecular Mechanisms submission deadline 30 May 2024 | 6 articles | Viewed by 8144 | Submission Open
Keywords: lipids; polyunsaturated fatty acids; lipid metabolism; lipid mediators; inflammation; neuroprotection
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Advances in Analytical Techniques for Biological and Medical Research
edited by
submission deadline 30 May 2024 | 4 articles | Viewed by 8006 | Submission Open
Keywords: HPLC; GC; electrophoresis; mass spectrometry; plant materials; validation; metabolomics; proteomics; protein– ligand interaction
(This special issue belongs to the Section Molecular Biology)
Biocatalysis and Bioactive Molecules: Future and Development submission deadline 30 May 2024 | 5 articles | Viewed by 7972 | Submission Open
Keywords: enzymatic synthesis; renewable sources; biocatalysis; enzymes; bioactive molecules; green chemistry; bioprocess; green catalysis; biotechnology; agro-industrial waste; immobilization; green solvent
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Pathophysiology to Novel Therapeutic Approaches for Leukemia
edited by
submission deadline 30 May 2024 | 5 articles | Viewed by 7420 | Submission Open
Keywords: acute myeloid leukemia; acute lymphoblastic leukemia; molecular pathophysiology; new therapeutic approaches; immunotherapy; cellular therapy; allogenic bone marrow transplantation
(This special issue belongs to the Section Molecular Oncology)
Biochemical and Molecular Changes in the Brain Caused by Drug Abuse: Implications for Therapeutic Intervention submission deadline 30 May 2024 | 6 articles | Viewed by 7229 | Submission Open
Keywords: substance use disorder; pharmacotherapy; addiction; relapse; vulnerability; drug self-administration; craving
(This special issue belongs to the Section Molecular Pharmacology)
Studies on Lactic Acid Bacteria and Their Products in Health and Diseases 2.0 submission deadline 30 May 2024 | 5 articles | Viewed by 6930 | Submission Open
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Exploring Molecular Mechanisms of Inflammatory Diseases
edited by
submission deadline 30 May 2024 | 3 articles | Viewed by 6923 | Submission Open
Keywords: immunity; inflammation; inflammatory disease
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Stress Signaling and Programmed Cell Death 2.0
edited by
submission deadline 30 May 2024 | 6 articles | Viewed by 6882 | Submission Open
Keywords: apoptosis; non-apoptotic cell death; inflammatory cell death; cancer; neurodegenerative disease.
(This special issue belongs to the Section Biochemistry)
Microbial Omics
edited by
submission deadline 30 May 2024 | 6 articles | Viewed by 6704 | Submission Open
Keywords: omics technologies; omics methodologies; microorganisms; proteomics; genomics; transcriptomics
(This special issue belongs to the Section Molecular Microbiology)
Molecular Advances in New Combination Therapies for Cancer
edited by Valeria Lucarini and
submission deadline 30 May 2024 | 5 articles | Viewed by 6376 | Submission Open
Keywords: immunotherapy; target therapy; chemotherapy; tumor microenvironment; combination therapies; preclinical models
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Mechanisms and New Therapies for Breast Cancer
edited by Mary Lou Cutler and
submission deadline 30 May 2024 | 5 articles | Viewed by 6262 | Submission Open
Keywords: management of metastatic disease; neoadjuvant therapy; chemotherapy and immunotherapy combination; novel biologics; aromatase inhibitors; outcome research; quality of life during and after breast cancer therapy; new targets for TNBC
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Neurometabolic Disorders in the Adults submission deadline 30 May 2024 | 2 articles | Viewed by 6039 | Submission Open
Keywords: Neurometabolic; Metabolic/biochemical pathways; Genetic defects; Pathological phenotypes
(This special issue belongs to the Section Molecular Neurobiology)
Tissue Engineering and Cell Therapy: Recent Progress
edited by
submission deadline 30 May 2024 | 3 articles | Viewed by 5631 | Submission Open
Keywords: biomaterials and cell sources for tissue engineering and cell therapy; tissue engineering of substitutes in vitro; functional testing of tissues reconstructed in vitro; extracellular matrix; mechanical characteristics; biological and histological characterization; translational research
(This special issue belongs to the Section Biochemistry)
Programmed Cell Death and Oxidative Stress 2.0
edited by
submission deadline 30 May 2024 | 6 articles | Viewed by 5517 | Submission Open
Keywords: oxidative stress; programmed cell death; cellular stresses; senescence; cytotoxicity; cancer; neurodegenerative disease; inflammatory disease; organelle stress
(This special issue belongs to the Section Biochemistry)
New Insights in Natural Bioactive Compounds 3.0 submission deadline 30 May 2024 | 7 articles | Viewed by 5488 | Submission Open
Keywords: inflammation; cytokines; ROS; oxidative stress; natural products; flavonoids; cannabinoids
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Metal-Organic Coordination Compounds: Synthesis, Structure, Spectra, Applications submission deadline 30 May 2024 | 5 articles | Viewed by 5351 | Submission Open
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Human and Animal Monocytes and Macrophages in Homeostasis and Disease 5.0 submission deadline 30 May 2024 | 5 articles | Viewed by 5325 | Submission Open
Keywords: monocytes; macrophages; inflammation; diseases; COVID-19; diabetes mellitus; polarity; phagocytosis; cytokine secretion; chemotaxis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Mechanisms and Therapies of Colorectal Cancer 3.0 submission deadline 30 May 2024 | 8 articles | Viewed by 5058 | Submission Open
Keywords: transforming growth factor beta (TGF-β ) signaling; genetic alterations; molecular targeted therapy precision medicine
(This special issue belongs to the Section Molecular Oncology)
Physiology and Pathology of Neurons 2.0
edited by
submission deadline 30 May 2024 | 3 articles | Viewed by 4686 | Submission Open
(This special issue belongs to the Section Molecular Neurobiology)
Mass Spectrometry in Molecular Biology
edited by
submission deadline 30 May 2024 | 3 articles | Viewed by 4550 | Submission Open
Keywords: mass spectrometry of biomolecules; native/modified peptides; proteins; lipids; and metabolites; sample preparation; extraction; and ionization techniques; ion fragmentation pattern recognition; statistical analysis of identification results
(This special issue belongs to the Section Molecular Informatics)
Current Research on Cancer Biology and Therapeutics 2.0 submission deadline 30 May 2024 | 4 articles | Viewed by 4533 | Submission Open
Keywords: antiangiogenic; anticancer therapy; antimetastatic; apoptosis; antiproliferative; cancer; peptides; signaling molecules; transcription factors; tumor
(This special issue belongs to the Section Molecular Oncology)
Drug Resistance in Cancer: Molecular Mechanisms and Tackling Strategies 2.0
edited by
submission deadline 30 May 2024 | 3 articles | Viewed by 4321 | Submission Open
Keywords: apoptosis; cancer; clinical trials; chemotherapy; drug metabolism; drug resistance; drug delivery; heterogeneity; immunotherapy; microenvironment
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Mechanisms of Angiogenesis and Cancer
edited by
submission deadline 30 May 2024 | 2 articles | Viewed by 3950 | Submission Open
Keywords: angiogenesis; cancer; tumor angiogenesis; VEGF signaling; VEGFR2; HIF1a; transcription factors; anti-angiogenesis; anti-angiogenic therapy; angiogenesis inhibitors; endothelia cells; tumor associated Endothelial cells; metastasis; hypoxia; cancer differentiation; cancer stem cells; endothelial cell differentiation
(This special issue belongs to the Section Molecular Oncology)
Molecular Mechanisms of Plant Biostimulants
edited by and Julietta Moustaka
submission deadline 30 May 2024 | 3 articles | Viewed by 3791 | Submission Open
Keywords: biostimulants; abiotic stresses; biotic stresses; plant growth promoter; stress acclimation; oxidative damage; photosynthetic efficiency; ROS; antioxidant mechanisms; redox regulation
(This special issue belongs to the Section Molecular Plant Sciences)
Muscle Proteins, Functions and Interactions
edited by
submission deadline 30 May 2024 | 3 articles | Viewed by 3735 | Submission Open
Keywords: muscle contraction; muscle regulation; myosin; actin; titin; troponin; tropomyosin; Z-line; M-line; sarcomere
(This special issue belongs to the Section Molecular Biophysics)
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