Clinics and Practice

Special Issue Editor

Dr. Vassilis Martiadis

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Guest Editor

Department of Mental Health, Community Mental Health Center DS 25, ASL Napoli 1 Centro, Naples, Italy
Interests: mental health; psychiatry; psychopharmacology; depression; schizophrenia; bipolar disorder; psychology

Special Issue Information

Dear Colleagues,

Child and adolescent mental health is a topical issue for society and for clinicians in both the psychiatry and psychology fields. Mental health problems, psychological distress, anxiety, depression and eating disorders have risen consistently after the pandemic, while severe mental diseases such as schizophrenia and bipolar disorder are constantly a matter of concern. Increasing and precocious use of substances further complicates the picture. Therefore, there is an increasing need for evidence-based treatments for child and adolescent mental health-related problems and mental diseases. The aim of this Special Issue is to share novel and evidence-based knowledge on pharmacological and psychological treatments for psychiatric disorders in pediatric and adolescent populations, taking into account both established treatments and future therapeutic options. Original Research, Reviews and Meta-analyses aiming to share clinical and practical knowledge on pharmacotherapies and/or psychotherapies for children and adolescents are welcome and will be peer-reviewed in a timely manner.

Dr. Vassilis Martiadis
Guest Editor

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Keywords

psychiatry
adolescent
child
treatment
psychology
mental health
psychopharmacology
psychotherapy

Published Papers (2 papers)

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Research

12 pages, 730 KiB

Open AccessArticle

Anxiety and Depression and Associated Risk Factors among Outpatients with Systemic Lupus Erythematosus: Eastern Province, Saudi Arabia

by Manal Ahmed Hasan, Wasayf Salman Almogaliq, Fatimah Habib Alhanabi, Hebah Abbas Aldrazi, Moath Thamer Alkhouzaie, Raed Albukhari, Safi Alqatari, Abdullah A. Al-Abdulwahab, Hajer Musaab AlZuhair and Mohammed T. Al-Hariri

Clin. Pract. 2024, 14(2), 486-497; https://doi.org/10.3390/clinpract14020037 - 19 Mar 2024

Viewed by 720

Abstract

Background: Although mood disorders are prevalent among systemic lupus erythematosus (SLE) patients, they are usually underrecognized. This study aimed to estimate the prevalence of anxiety and depression among Saudi SLE patients. Methods: This cross-sectional study was conducted among SLE patients from July 2022 to June 2023 in the Eastern Province of Saudi Arabia. A self-reported questionnaire was used to collect the data through validated tools including the Hamilton Anxiety Rating Scale-A and the Beck Depression Inventory score. Results: There were 133 females (91.7%) and 12 males (8.3%) included in this study. Based on the HAM-A score, 45.5% of participants had an anxiety disorder, and according to the BDI score, 46.2% had a depression disorder. Anxiety and depression were significantly associated with a longer duration of SLE, unemployment status, smoking, and the presence of comorbidities. Moreover, the present study found a significant association between depression and male gender. Conclusion: This study found that Saudi SLE patients have a high prevalence of both anxiety and depression. Therefore, SLE patients should be screened for neuropsychiatric disorders during routine follow-ups and managed as early as possible. Full article

(This article belongs to the Special Issue Pediatric and Adolescent Psychiatry and Psychology: Current Treatments and Future Options)

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13 pages, 897 KiB

Open AccessArticle

Serum Markers of Brain Injury in Pediatric Patients with Congenital Heart Defects Undergoing Cardiac Surgery: Diagnostic and Prognostic Role

by Lacramioara Eliza Chiperi, Adina Huţanu, Cristina Tecar and Iolanda Muntean

Clin. Pract. 2023, 13(5), 1253-1265; https://doi.org/10.3390/clinpract13050113 - 23 Oct 2023

Viewed by 1253

Abstract

Introduction: The objectives of this study were to assess the role of neuromarkers like glial fibrillary acidic protein (GFAP), brain-derived neurotrophic factor (BDNF), protein S100 (pS100), and neuron-specific enolase (NSE) as diagnostic markers of acute brain injury and also as prognostic markers for short-term neurodevelopmental impairment. Methods: Pediatric patients with congenital heart defects (CHDs) undergoing elective cardiac surgery were included. Neurodevelopmental functioning was assessed preoperatively and 4–6 months postoperatively using the Denver Developmental Screening Test II. Blood samples were collected preoperatively and postoperatively. During surgery, regional cerebral tissue oxygen saturation was monitored using near-infrared spectroscopy (NIRS). Results: Forty-two patients were enrolled and dichotomized into cyanotic and non-cyanotic groups based on peripheric oxygen saturation. Nineteen patients (65.5%) had abnormal developmental scores in the non-cyanotic group and eleven (84.6%) in the cyanotic group. A good diagnostic model was observed between NIRS values and GFAP in the cyanotic CHD group (AUC = 0.7). A good predicting model was observed with GFAP and developmental scores in the cyanotic CHD group (AUC = 0.667). A correlation was found between NSE and developmental quotient scores (r = 0.09, p = 0.046). Conclusions: From all four neuromarkers studied, only GFAP was demonstrated to be a good diagnostic and prognostic factor in cyanotic CHD patients. NSE had only prognostic value. Full article

(This article belongs to the Special Issue Pediatric and Adolescent Psychiatry and Psychology: Current Treatments and Future Options)

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