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Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Linking Genomic Mutations to Antimicrobial Resistance and Virulence

edited by

Eduardo Alvarez Duarte

submission deadline 30 Mar 2026 | Viewed by 212 | Submission Open

Keywords: antifungal resistance; antifungal drugs; antibiotics; resistance; antimicrobial resistance; genetic mutations; SNP

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Optimizing Antibiotic Use and Consumption: Integrating Surveillance, Policy and Practice

edited by

Paola Lichtenberger

submission deadline 30 Mar 2026 | Viewed by 204 | Submission Open

Keywords: infectious disease; antimicrobial stewardship; antibiotic use; antimicrobial consumption; point prevalence survey

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antimicrobials Use: Clinical Safety to Environmental Risk—Learning from One Health Approach

edited by

Anabela Almeida

Leonor M. Meisel

and

Ana Fortuna

submission deadline 31 Mar 2026 | 8 articles | Viewed by 43568 | Submission Open

Keywords: antimicrobials; antifungals; antiviral; environment; antimicrobial resistance; pharmacokinetics; risk-assessment; prioritisation; One-Health

Antibiotics as Major Disruptors of Gut Microbiota

edited by

Gábor Ternák

submission deadline 31 Mar 2026 | 6 articles | Viewed by 39367 | Submission Open

Keywords: microbiome; gut flora; development of gut flora; dysbiosis; antibiotics; antibiotic classes; antibiotic consumption; gut– brain axis; short-chain fatty acids; metabolom; mediator molecules; composition of gut flora

Membranes to Fight Drug-Resistant Microbes

edited by

Nermina Malanovic

submission deadline 31 Mar 2026 | 6 articles | Viewed by 24100 | Submission Open

Keywords: antimicrobial peptides; membrane-active compounds; mode of action; lipidoids; vaccines

(This special issue belongs to the Section Antimicrobial Peptides)

Managing Appropriate Antibiotic Prescribing and Use in Primary Care

edited by

Ruby Biezen

submission deadline 31 Mar 2026 | 6 articles | Viewed by 16993 | Submission Open

Keywords: primary care; general practice; antimicrobial stewardship; antimicrobial resistance; infectious disease; appropriate prescribing; guidelines concordance

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antibiotic Resistance: From the Bench to Patients, 2nd Edition

edited by

Fernando Albericio

and

Márió Gajdács

submission deadline 31 Mar 2026 | 6 articles | Viewed by 16426 | Submission Open

Keywords: antimicrobial resistance; infectious disease epidemiology; multidrug resistance; clinical bacteriology; antimicrobial stewardship; self-medication; knowledge– attitude– practice (KAP); regulatory perspectives; drug utilization; policy analysis; primary care; pharmacy; novel antimicrobial drugs; laboratory testing

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Companion Animals: Antimicrobial Resistance in Bacterial and Fungal Pathogens Associated with Skin and Ear Infections

edited by

Dominik Łagowski

and

Ewelina Czyzewska-Dors

submission deadline 31 Mar 2026 | 5 articles | Viewed by 13855 | Submission Open

Keywords: dermatophytes; Candida; companion animals; drug susceptibility; Malassezia; mechanisms of resistance; molecular detection; Pseudomonas; Staphylococcus; One Health; MDR; veterinary

(This special issue belongs to the Section Antibiotics in Animal Health)

Strategies to Combat Antibiotic Resistance and Microbial Biofilms

edited by

Isabella Macário Ferro Cavalcanti

submission deadline 31 Mar 2026 | 4 articles | Viewed by 11855 | Submission Open

Keywords: antibiotic resistance; biofilms; nanotechnology; medicinal plants; synthetic

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antibiotics: Fighting Disease and Promoting Health by Embracing the Two Sides of the Same Coin

edited by

Chrysoula Voidarou

Elisavet Stavropoulou

and

Eugenia Bezirtzoglou

submission deadline 31 Mar 2026 | 4 articles | Viewed by 10737 | Submission Open

Keywords: antibiotics; probiotics; antibacterial activity; functional food; natural compounds; natural antimicrobials; microbiome; antimicrobial resistance; resistome

(This special issue belongs to the Section The Global Need for Effective Antibiotics)

Genomic Insights and Implications of Emerging Antimicrobial Resistance

edited by

Daniela Bencardino

and

Christian Berens

submission deadline 31 Mar 2026 | 4 articles | Viewed by 8433 | Submission Open

Keywords: antibiotic-resistance; molecular typing; genomic technologies; high-threat pathogens; epidemiological surveillance; emerging and re-emerging infectious diseases; one health approach

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Periodontal Bacteria and Periodontitis: Infections and Therapy

edited by Anna Skurska

submission deadline 31 Mar 2026 | 3 articles | Viewed by 6523 | Submission Open

Keywords: periodontitis; infection; antibiotics; antibacterial activities

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antimicrobial and Antioxidant Efficacy of Essential Oils

edited by

Mijat Božović

submission deadline 31 Mar 2026 | 1 articles | Viewed by 6162 | Submission Open

Keywords: essential oils; chemical analysis; extraction methods; antimicrobial activity; antioxidant potential

(This special issue belongs to the Section Plant-Derived Antibiotics)

Epidemiology and Genomics of Antimicrobial Resistance of Difficult-to-Treat Pathogens

edited by Simone Ambretti

submission deadline 31 Mar 2026 | 5 articles | Viewed by 5427 | Submission Open

Keywords: antimicrobial resistance; difficult-to-treat pathogens; epidemiology; genomics; MRSA; VRE; ESBL; CRE; CRAB; MDR pseudomonas aeruginosa

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Advances in Infective Endocarditis Research: From Bench to Bedside

edited by Joya-Rita Hindy

submission deadline 31 Mar 2026 | 3 articles | Viewed by 5403 | Submission Open

Keywords: infective endocarditis; prosthetic valve endocarditis; cardiac implantable electronic devices; recurrent infective endocarditis; valvular heart disease; cardiac surgery; molecular diagnostics; innovative drug delivery; antimicrobial resistance; suppressive therapy

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antibiotic Resistance and Virulence in Bacterial Isolates: A Genomic Perspective from Human and Animal Sources

edited by

Sónia Ramos

and

Alexandra Nunes

submission deadline 31 Mar 2026 | 3 articles | Viewed by 5190 | Submission Open

Keywords: MDRB; antimicrobial resistance; one health; mobile genetic elements; AMR; antimicrobial resistance gene

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Nanotechnology-Based Antimicrobials and Drug Delivery Systems

edited by

Mihai Valentin Predoi

Simona Liliana Iconaru

and

Carmen Steluta Ciobanu

submission deadline 31 Mar 2026 | 3 articles | Viewed by 4162 | Submission Open

Keywords: antimicrobial agents; nanocarriers; antimicrobial coatings; polymers nanocomposite; drug delivery systems

(This special issue belongs to the Section Novel Antimicrobial Agents)

A Themed Issue in Honor of Prof. Dr. Rob Capon—Outstanding Contributions in the Field of Anti-Infectives

edited by Mark Butler

submission deadline 31 Mar 2026 | 2 articles | Viewed by 4099 | Submission Open

Keywords: natural product; microorganism; bacteria; fungi; marine antibiotic; antibacterial; antheminthic; crop protection

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antimicrobial Activities of Bioactive Components from Honeybee Products

edited by

Otilia Bobis

Adriana Cristina Urcan

and

Claudia Pașca

submission deadline 31 Mar 2026 | 1 articles | Viewed by 4087 | Submission Open

Keywords: bee products; antibiotics; antimicrobial activity; bioactive compounds; honey; propolis; bee pollen/beebread; royal jelly; bee venom; microbial resistance

(This special issue belongs to the Section Novel Antimicrobial Agents)

Combating Antimicrobial Resistance Spread in Food and Drinks Using Bacteriophage Technologies

edited by

Janet Nale

submission deadline 31 Mar 2026 | 2 articles | Viewed by 3957 | Submission Open

Keywords: bacteriophage; phage therapy; antimicrobial resistance; food; drink; water; agriculture; pathogenic bacteria; lytic phages; lysogens; prophages; temperate phage

(This special issue belongs to the Section Bacteriophages)

Genetic Characterization of Antimicrobial Resistance under the One Health Approach

edited by

Sandra M. Quinteira

and

Olga Maria Lage

submission deadline 31 Mar 2026 | 2 articles | Viewed by 3287 | Submission Open

Keywords: antimicrobial resistance; multidrug-resistant bacteria; resistance genes; mobile genetic elements; molecular mechanisms of resistance; One Health; epidemiology of AMR; AMR surveillance

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Discovery of Novel Antimicrobial Peptides Using Machine Learning and Molecular Dynamic Simulations

edited by

Lei Zhao

Liang Zhao

and

Fei Pan

submission deadline 31 Mar 2026 | 1 articles | Viewed by 2682 | Submission Open

Keywords: antimicrobial peptide; computational design; machine learning; deep learning; molecular dynamic simulations; de novo generation

(This special issue belongs to the Section Antimicrobial Peptides)

Antibiotics in the Environment: Sources, Fate, and Mitigation Strategies

edited by Khaled Benis

submission deadline 31 Mar 2026 | 1 articles | Viewed by 2574 | Submission Open

Keywords: antibiotic contamination; environmental fate; antibiotic resistance; mitigation strategies; pollution management

Antibiotic Synthesis, 2nd Edition

edited by

Naresh Kumar

and

Tsz Tin Yu

submission deadline 31 Mar 2026 | 2 articles | Viewed by 2326 | Submission Open

Keywords: new antimicrobial compounds; dual-action antimicrobials; new antimicrobial targets; targeted delivery of antibiotics; new scaffolds for antimicrobial discovery; discovery of new antimicrobial mechanisms

(This special issue belongs to the Section Novel Antimicrobial Agents)

Biomaterial-Based Delivery Systems for Natural Antimicrobials to Overcome Microbial Resistance

edited by

Ioana Cristina Marinas

Irina Gheorghe-Barbu

and Ilda Czobor-Barbu

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1931 | Submission Open

Keywords: antimicrobial resistance (AMR); virulence and pathogenicity; phytocompounds; biomaterials; controlled release; nanoparticles; biopolymers; targeted delivery; biofilm prevention; sustainable therapeutics

(This special issue belongs to the Section Antimicrobial Materials and Surfaces)

Surveillance and Detection of Antimicrobial Resistance: Tools and Trends

edited by

Hung-Sheng Shang

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1663 | Submission Open

Keywords: antimicrobial resistance; surveillance systems; pathogen detection; rapid diagnostics; genomic surveillance; artificial intelligence; point-of-care testing; public health strategy; molecular epidemiology; big data analytics

Current Challenges in Antimicrobial Stewardship

edited by

Andreas A. Von Ameln-Mayerhofer

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1615 | Submission Open

Keywords: antimicrobial stewardship; antimicrobial resistance; antibiotics prescribing; intervention; irrational prescriptions; surveillance; therapeutic monitoring; ABS; AMS; antibiotic stewardship; best practice; interprofessional; rational prescribing; DDD/100; RDD/100

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Global Partnerships in Response to Antimicrobial Resistance: From Policy to Practice

edited by

Helena Rosado

submission deadline 31 Mar 2026 | 1 articles | Viewed by 1078 | Submission Open

Keywords: antimicrobial resistance; antimicrobial stewardship; global health partnerships; collaboration; low- and middle-income countries; health systems strengthening; actionable implementation; AMR interventions

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antibiotic Susceptibility Testing and Rapid Diagnostics of Antimicrobial Resistance

edited by Maria Grazia Bocci and Giulia Capecchi

submission deadline 31 Mar 2026 | Viewed by 381 | Submission Open

Keywords: antimicrobial resistance; antibiotic susceptibility testing; rapid diagnostics; molecular detection; point-of-care testing; clinical microbiology

Interdisciplinary Applications of Micro- and Nano-Antimicrobials

edited by Cleonice Gonçalves da Rosa and Michael Ramos Nunes

submission deadline 31 Mar 2026 | Viewed by 335 | Submission Open

Keywords: micro- and nano-antimicrobials; antimicrobial coatings; nanotechnology in medicine; food safety and packaging; agricultural applications; antibiotic resistance; environmental remediation; controlled release systems; pathogen management; antimicrobial materials

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antimicrobial Peptides in Agriculture and Food Safety

edited by

Da Teng

submission deadline 31 Mar 2026 | Viewed by 325 | Submission Open

Keywords: AI-based discovery and design; biotechnology; mechanisms of action; novel delivery systems; animal husbandry; aquaculture; plant conservation; food preservation

Beyond Bacteria: Exploring the Biology and Treatment of Understudied Fungal Biofilms

edited by

Whitni Redman

and

Wolf-Rainer Abraham

submission deadline 31 Mar 2026 | Viewed by 287 | Submission Open

Keywords: fungal biofilms; bacterial biofilms; interkingdom biofilms; host-pathogen interactions; biofilms and methodologies; mixed-species infections; therapeutics; fungal– bacterial interactions

(This special issue belongs to the Section Antibiofilm Strategies)

Genomic Characterization of Antimicrobial Resistance and Evolution Mechanism of Bacteria, 2nd Edition

edited by

Daniel Gyamfi Amoako

and

Linda Bester

submission deadline 31 Mar 2026 | Viewed by 156 | Submission Open

Keywords: antimicrobial resistance mechanism; mobile genetic element; horizontal gene transfer; resistome; evolution; molecular phylogenetics; genomics; bioinformatics analysis; next-generation sequencing

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antibiotic Choices for Pediatric Infections

edited by Theodouli Stergiopoulou

submission deadline 1 Apr 2026 | 2 articles | Viewed by 1379 | Submission Open

Keywords: pediatric; neonatal infectious diseases; antimicrobial agents; antibiotic treatment

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antimicrobial Resistance of Staphylococcus spp. in Animals: A One Health Perspective

edited by Gi Yong Lee

submission deadline 5 Apr 2026 | 2 articles | Viewed by 1833 | Submission Open

Keywords: staphylococci; molecular epidemiology; antimicrobial resistance; One Health; multiomics

(This special issue belongs to the Section Antibiotics in Animal Health)

Microbial Resistance Surveillance and Management in Food Systems

edited by

Carlos Adam Conte Júnior

and

Bruno Dutra da Silva

submission deadline 20 Apr 2026 | 6 articles | Viewed by 15373 | Submission Open

Keywords: cross-contamination; microbial resistance; microbial monitoring; public health; alternative antimicrobials; foodborne illnesses; food microbiology

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Novel Preventive and Therapeutic Strategies to Eradicate Biofilm Infections Based on New Antibacterial Compounds

edited by

María Guembe

submission deadline 20 Apr 2026 | Viewed by 299 | Submission Open

Keywords: antibacterial; biofilm; infection; innovation; microbiota

(This special issue belongs to the Section Antibiofilm Strategies)

Antimicrobial Resistance in the Era of Climate Change

edited by

Natalia G. Vallianou

and Eleni Geladari

submission deadline 25 Apr 2026 | 5 articles | Viewed by 12231 | Submission Open

Keywords: climate change; extremes in temperature; antimicrobial resistance (AMR)

Artificial Intelligence and Antimicrobial Resistance: Innovation, Global Challenges and the Future of Healthcare

edited by

Fabio Scarpa

and

Francesco Branda

submission deadline 30 Apr 2026 | 2 articles | Viewed by 16808 | Submission Open

Keywords: antimicrobial resistance; artificial intelligence; digital health; drug discovery; patient-centric care; therapeutic innovations

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antimicrobial Resistance in Biofilm-Associated Infections

edited by

Fazlurrahman Khan

Nazia Tabassum

and

Young-Mog Kim

submission deadline 30 Apr 2026 | 6 articles | Viewed by 14853 | Submission Open

Keywords: biofilms; antimicrobial resistance; chronic infections; biofilm matrix; virulence factors; antibiotic efficacy; pathogen persistence; biofilm formation; medical implants; quorum sensing

(This special issue belongs to the Section Antibiofilm Strategies)

New Paradigms Concerning the Production of Antibiotics: Between Ecological Responsibility and Revalorization of Narrow Spectrums

edited by

Véronique Mondain

submission deadline 30 Apr 2026 | 3 articles | Viewed by 11122 | Submission Open

Keywords: one health; environmental pollution; human health; antimicrobial production; livestock; antimicrobial resistance; antimicrobial stewardship

(This special issue belongs to the Section The Global Need for Effective Antibiotics)

Metal-Based Complexes as Novel Antimicrobial Strategies

edited by

Alberto Aragón-Muriel

Dorian Polo Cerón

and

David Morales-Morales

submission deadline 30 Apr 2026 | 1 articles | Viewed by 8079 | Submission Open

Keywords: antibiotics; metal-based complexes; antimicrobial resistance; antimicrobial therapy; drug design; bioinorganic; metallodrug; metallopharmaceutical

(This special issue belongs to the Section Novel Antimicrobial Agents)

Microbial Natural Products as a Source of Novel Antimicrobials, 2nd Edition

edited by

Patricia Branco

and

Elisabete Muchagato Mauricio

submission deadline 30 Apr 2026 | 2 articles | Viewed by 7556 | Submission Open

Keywords: antimicrobial peptides; mycocins; bacteriocins; antimicrobial activity; biopreservatives

(This special issue belongs to the Section Novel Antimicrobial Agents)

Antimicrobial Stewardship—from Projects to Standard of Care

edited by Gesche Först and Franky Buyle

submission deadline 30 Apr 2026 | 5 articles | Viewed by 7326 | Submission Open

Keywords: antimicrobial stewardship; antimicrobial use; antibiotics; implementation; efficacy; quality; antimicrobial prescribing

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antibiotic Resistance in a One Health Context: Bridging Environmental, Agricultural, Nutritional, Veterinary, and Clinical Perspectives

edited by

Pedro A. Jiménez Gómez

and

Marina Robas Mora

submission deadline 30 Apr 2026 | 7 articles | Viewed by 7304 | Submission Open

Keywords: antibiotic resistance; One Health; environmental microbiology; zoonotic pathogens; antimicrobial stewardship; resistance mechanisms; horizontal gene transfer; integrated surveillance; microbial ecology; public health

(This special issue belongs to the Section Antibiotics in Animal Health)

Strategies for the Design of Hybrid-Based Antimicrobial Compounds

edited by

Vuyolwethu Khwaza

Sibusiso Alven

and

Blessing Atim Aderibigbe

submission deadline 30 Apr 2026 | 4 articles | Viewed by 5335 | Submission Open

Keywords: hybrid compounds; antimicrobial agents; antibacterial agents; antifungal activity; antiviral activity; in vitro evaluation; structure– activity relationship (SAR); bioactive molecules; nanoformulations; targeted drug delivery; pharmacological screening; clinical studies

(This special issue belongs to the Section Novel Antimicrobial Agents)

Prevalence, Treatment and Antibacterial Resistance of Urinary Tract Infections

edited by Alin Gabriel Mihu and

Tudor Rares Olariu

submission deadline 30 Apr 2026 | 2 articles | Viewed by 4778 | Submission Open

Keywords: urinary tract infections; UTI; antibiotic; antibacterial; resistance; uropathogens; recurrent UTI; Enterobacteriaceae; Escherichia coli

Perspective on the Role of Farm Animals in the Transmission of Antimicrobial Resistance from a One Health Approach

edited by

Romeo Teodor Cristina

and

Degi Janos

submission deadline 30 Apr 2026 | 2 articles | Viewed by 4236 | Submission Open

Keywords: antimicrobials use; farm animals; antimicrobial resistance; one health; antimicrobials; food safety; public health

(This special issue belongs to the Section Antibiotics in Animal Health)

Evidence in Antibiotic Mastitis Therapy

edited by

Volker Krömker

and

Paolo Moroni

submission deadline 30 Apr 2026 | 1 articles | Viewed by 3981 | Submission Open

Keywords: antibiotic mastitis treatment; targeted; selective; pathogens; mastitis history; new infections

(This special issue belongs to the Section Antibiotics in Animal Health)

Antimicrobial Peptides: An Emerging Hope in the Era of New Infections and Resistance, 2nd Edition

edited by

Piyush Baindara

submission deadline 30 Apr 2026 | 1 articles | Viewed by 3499 | Submission Open

Keywords: antimicrobial peptides; antimicrobial resistance; infectious diseases; antibacterial; antifungal; immunomodulatory properties; therapeutics; evolution

(This special issue belongs to the Section Antimicrobial Peptides)

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