Special Issues

AI publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Privacy-Preserving Deep Learning Techniques for Audio Data: Challenges and Advances
edited by , , Francesco Rundo and Angelo Alberto Messina
submission deadline 5 Mar 2026 | Viewed by 812 | Submission Open
Keywords: privacy; audio processing; deep learning; federated learning; differential privacy; speech recognition; speaker identification; secure AI; adversarial privacy; explainable AI
AI Learning for Control of Predictive Vehicle Dynamics
edited by
submission deadline 27 Mar 2026 | Viewed by 504 | Submission Open
Keywords: vehicle dynamics control; deep learning; autonomous and connected vehicle control; model predictive control; physics-informed neural network; safety; energy consumption; learning control; integration of AI and control; human-centric AI for vehicle dynamics control
Safe and Secure Artificial Intelligence (AI) in Chemical Engineering: Current and Future Developments
edited by and Rajeevan Arunthavanathan
submission deadline 31 Mar 2026 | 1 articles | Viewed by 3118 | Submission Open
Keywords: Artificial Intelligence (AI); Machine Learning (ML); Artificial General Intelligence (AGI); chemical engineering; safety; security; process optimization; predictive maintenance; cybersecurity; risk management; regulatory compliance; ethical considerations; interdisciplinary integration; best practices; case studies; emerging trends; future directions; data integrity; system reliability; process control; industrial automation
(This special issue belongs to the Section Chemical Artificial Intelligence)
The Use of Artificial Intelligence in Business: Innovations, Applications and Impacts
edited by , Hossam Ali-Hassan and
submission deadline 31 Mar 2026 | 1 articles | Viewed by 2313 | Submission Open
Keywords: transformation; smart business solutions; predictive innovation; AI-driven strategy; machine learning insights; automated intelligence; generative AI applications; future of work; ethical AI in business; digital decision-making; intelligent enterprise
(This special issue belongs to the Section AI Systems: Theory and Applications)
When Trust Meets Intelligence: The Intersection Between Blockchain, Artificial Intelligence and Internet of Things submission deadline 31 Mar 2026 | 1 articles | Viewed by 1928 | Submission Open
Keywords: blockchain; IoT; AI; soft computing; neural networks; IOTA; distributed ledger; secure infrastructures; ethical AI
(This special issue belongs to the Section AI Systems: Theory and Applications)
AI in the Cloud: Innovative Applications and Practices Across Multiple Fields submission deadline 31 Mar 2026 | Viewed by 508 | Submission Open
Keywords: cloud computing; artificial intelligence; industry applications; communications technology; multi-agent systems; social computing; time-series analysis; optimization; resource management; collaboration; decision-making
AI-Powered Innovations in Blockchain and Cybersecurity: Advances, Challenges, and Future Prospects
edited by , David Zorrilla and
submission deadline 31 Mar 2026 | Viewed by 364 | Submission Open
Keywords: AI in blockchain security; machine learning for cybersecurity; smart contract auditing; decentralized AI networks; AI for threat detection; federated learning in blockchain; quantum-safe cryptography; secure IoT and edge computing; blockchain-based cybersecurity solutions; AI governance in decentralized systems
(This special issue belongs to the Section AI Systems: Theory and Applications)
AI for Sustainable and Resilient Cyber-Physical Systems
edited by Jin Wei-Kocsis
submission deadline 31 Mar 2026 | Viewed by 255 | Submission Open
Keywords: artificial intelligence (AI); cyber-physical System (CPS); sustainability; resilience; security; privacy
(This special issue belongs to the Section AI Systems: Theory and Applications)
Smart Worlds: Merging AI and Extended Reality for a New Era
edited by , Maria Concetta Carruba and
submission deadline 15 Apr 2026 | Viewed by 506 | Submission Open
Keywords: smart worlds; artificial intelligence (AI); extended reality (XR); virtual reality (VR); augmented reality (AR); mixed reality (MR); immersive environments; intelligent systems; real-time interaction; data-driven experiences
(This special issue belongs to the Section AI Systems: Theory and Applications)
Building Fast and Secure Deep Learning-Driven Applications in Healthcare
edited by , Ting Zhang and
submission deadline 15 Apr 2026 | Viewed by 356 | Submission Open
Keywords: healthcare; robotics; edge device; security
AI in Bio and Healthcare Informatics
edited by , and Nur Alam Md
submission deadline 30 Apr 2026 | 8 articles | Viewed by 18643 | Submission Open
Keywords: artificial intelligence (AI); healthcare informatics; bioinformatics; machine learning; deep neural network; medical image analysis
(This special issue belongs to the Section Medical & Healthcare AI)
AI-Driven Innovations in Medical Computer Engineering and Healthcare
edited by , Ping Lu, Jens Lundström and
submission deadline 30 Apr 2026 | 1 articles | Viewed by 1373 | Submission Open
Keywords: artificial intelligence diagnostics; clinical decision support; telemedicine; remote monitoring; wearables; predictive analytics; biomedical signals; personalized medicine; healthcare automation; explainability
(This special issue belongs to the Section Medical & Healthcare AI)
Development and Design of Autonomous Robot submission deadline 30 Apr 2026 | 1 articles | Viewed by 747 | Submission Open
Keywords: autonomous robots; sensor integration; machine learning; deep learning; real-time decision-making; robotics applications; robot mobility; industrial robotics; robotic perception
(This special issue belongs to the Section AI in Autonomous Systems)
AI for Smart Aging: Predictive, Assistive, and Humanized Technologies in Elder Care
edited by and ChenChang Wu
submission deadline 30 Apr 2026 | Viewed by 655 | Submission Open
Keywords: smart aging; artificial intelligence in elder care; predictive analytics; assistive robotics; emotion-aware systems; AI companions; gerontechnology; aging in place; cognitive decline detection; human-centered AI; ethical AI in healthcare; digital health for older adults
(This special issue belongs to the Section Medical & Healthcare AI)
Theory and Application in Merging AI with Blockchain Technology submission deadline 30 Apr 2026 | Viewed by 535 | Submission Open
Keywords: artificial intelligence; blockchain; AI– blockchain convergence; data sharing; consensus mechanisms; AI security
Deep Learning Technologies and Their Applications in Image Processing, Computer Vision, and Computational Intelligence
edited by and
submission deadline 15 May 2026 | 5 articles | Viewed by 6231 | Submission Open
Keywords: deep learning models and algorithms; machine learning theory and technology; image processing theory and applications; computer graphics and computational photography; computer vision techniques and applications; multimedia technology
Digital Health: AI-Driven Personalized Healthcare and Applications submission deadline 15 May 2026 | 1 articles | Viewed by 1202 | Submission Open
Keywords: artificial intelligence; personalized healthcare; digital health; predictive modelling; precision medicine; wearable devices; explainable AI; health informatics; clinical decision support system; federated learning
(This special issue belongs to the Section Medical & Healthcare AI)
The Future of Image Processing: Leveraging Pattern Recognition and AI
edited by
submission deadline 16 May 2026 | 1 articles | Viewed by 570 | Submission Open
Keywords: image processing; pattern recognition; image segmentation; image classification; medical imaging; interpretable AI; multimodal analysis; domain adaptation; medical imaging; remote sensing
(This special issue belongs to the Section Medical & Healthcare AI)
Applications of Deep Learning and Generative AI in Neuro-Medicine and Brain-Centric Interfaces
edited by
submission deadline 20 May 2026 | Viewed by 372 | Submission Open
Keywords: deep learning; brain– computer interface (BCI); EEG/fNIRS/MRI; cognitive workload; epilepsy detection; stroke rehabilitation; autism spectrum disorder; generative AI; multimodal neuroimaging; explainable AI
(This special issue belongs to the Section Medical & Healthcare AI)
AI for Good
edited by Manolya Kavakli-Thorne
submission deadline 30 May 2026 | Viewed by 803 | Submission Open
Keywords: artificial intelligence; machine learning; mixed reality; disruptive technologies; wellbeing
Controllable and Reliable AI
edited by Li Xiao, Yongping Xiong and Jingjia Zhang
submission deadline 31 May 2026 | 2 articles | Viewed by 6520 | Submission Open
Keywords: computer vision; edge computing; foundation models; integrated sensing and communication; internet of things; ethics and policy
(This special issue belongs to the Section AI Systems: Theory and Applications)
Machine Learning in Action: Practical Applications and Emerging Trends submission deadline 31 May 2026 | 2 articles | Viewed by 2681 | Submission Open
Keywords: applied machine learning; real-world deployment; domain-specific machine learning; machine learning systems in production; practical challenges in machine learning; data-driven decision making; case studies in machine learning; evaluation of machine learning applications; translational machine learning; machine learning for domain-centered applications
Artificial Intelligence in the Integration of Information Systems: Current Trends and Future Opportunities submission deadline 5 Jun 2026 | Viewed by 2597 | Submission Open
Keywords: artificial intelligence; system integration; sustainable information systems; smart cities; green AI; circular economy; ESG analytics; data transparency
The Future of Robotics: AI Algorithms, Ethics, and Real-World Applications
edited by , Nikolaos Vasilopoulos and Paraskevas Diamantatos
submission deadline 15 Jun 2026 | 1 articles | Viewed by 1482 | Submission Open
Keywords: artificial intelligence; automation systems; machine learning; intelligent control; autonomous robotics; computer vision; sensor fusion; digital twins; predictive maintenance; human-machine interaction
(This special issue belongs to the Section AI in Autonomous Systems)
Intelligent Defenses: The Role of AI in Strengthening Information Security submission deadline 26 Jun 2026 | 1 articles | Viewed by 1798 | Submission Open
Keywords: artificial intelligence (AI); cybersecurity; intelligent defense systems; machine learning; deep learning; intrusion detection systems (IDS); threat intelligence; anomaly detection; malware detection; behavioral analytics  ; automated incident response; adversarial AI; cyber threat prediction; security automation; data privacy; ethical AI; real-time threat detection; AI-driven cyber defense; security analytics; digital infrastructure protection
(This special issue belongs to the Section AI in Autonomous Systems)
Large Language Models and Retrieval-Augmented Generation in Natural Language Processing, Human–Robot Interaction and Quantum Computing
edited by
submission deadline 30 Jun 2026 | 1 articles | Viewed by 7363 | Submission Open
Keywords: large language models; retrieval-augmented generation; natural language processing; knowledge graphs; knowledge grounding; human– robot interaction; agentic computing; vision– language– action models; quantum computing; quantum-enhanced information retrieval; evaluation methodologies; reliability assessment; explainability; hallucination mitigation; vector search optimization; quantum code generation; multi-modal RAG
(This special issue belongs to the Section AI Systems: Theory and Applications)
Human-Computer Interaction and Human-Centered AI submission deadline 30 Jun 2026 | Viewed by 408 | Submission Open
Keywords: human-centered AI; human– computer interaction; explainable AI; responsible AI; trust in AI; mental models; adaptive systems; user experience; fairness and ethics; human– AI collaboration; interaction design; cognitive models; value-sensitive design; behavioral responses to AI
(This special issue belongs to the Section AI Systems: Theory and Applications)
Measuring What Matters: AI and the Future of Fair Assessment
edited by
submission deadline 1 Jul 2026 | Viewed by 510 | Submission Open
Keywords: artificial intelligence; educational assessment; fairness; equity in education; algorithmic bias; adaptive testing; ethical AI; inclusive assessment
(This special issue belongs to the Section AI Systems: Theory and Applications)
The Digital Immune System: AI-Driven Detection and Mitigation of Online Harms
edited by , and Hisami Suzuki
submission deadline 15 Jul 2026 | 1 articles | Viewed by 3655 | Submission Open
Keywords: disinformation/misinformation/malinformation; hate speech/toxic language/cyberbullying; propaganda analysis; adversarial learning/adversarial defense; causal inference/explainable AI (XAI)/interpretability; content moderation/counter-narrative generation; AI trust and safety
Transforming Biomedical Innovation with Artificial Intelligence submission deadline 15 Jul 2026 | 4 articles | Viewed by 2488 | Submission Open
Keywords: artificial intelligence in biomedicine; machine learning for health and disease; deep learning for biomedical innovation; medical imaging and computational diagnostics; digital health technologies and wearable AI devices; bioinformatics and computational biology; clinical decision support and predictive analytics; explainable; robust; and ethical AI in healthcare; multimodal biomedical data fusion; AI for drug discovery and personalized therapeutics
Innovative Artificial Intelligent Solutions for a Sustainable Future
edited by
submission deadline 25 Jul 2026 | Viewed by 380 | Submission Open
Keywords: machine learning; deep learning; natural language processing; computer vision; sustainable cultural education; digital cultural heritage preservation; artistic innovation; social governance; collaborative development
Development of Artificial Intelligence and Computational Thinking: Future Directions, Opportunities, and Challenges submission deadline 31 Jul 2026 | 4 articles | Viewed by 14063 | Submission Open
Keywords: Artificial Intelligence (AI); computational thinking; machine learning; data science; algorithms; educational technology; ethical  AI; automation; problem solving; future trends; digital literacy; algorithmic bias; educational innovation; society and technology; innovation in education
AI Applications in Emergency Response and Fire Safety
edited by Yoon J. Ko and Ankit Agrawal
submission deadline 31 Jul 2026 | 1 articles | Viewed by 1720 | Submission Open
Keywords: predictive analytics; enhanced detection; situational awareness; and hazard scoping; automating data processes; optimizing response/firefighting/evacuation strategies; supporting/improving decision-making; data management and analysis for risk assessment; smart emergency/fire modeling
(This special issue belongs to the Section AI in Autonomous Systems)
AI for Industrial Operation and Maintenance: Recognition Challenges with Limited Data Condition submission deadline 31 Jul 2026 | 1 articles | Viewed by 1119 | Submission Open
Keywords: industrial artificial intelligence; predictive maintenance; few-shot learning; fault diagnosis; data-efficient learning; transfer learning; digital twin; uncertainty quantification
Sensing the Future: IOT-AI Synergy for Climate Action
edited by
submission deadline 31 Jul 2026 | 1 articles | Viewed by 961 | Submission Open
Keywords: IoT for climate action; AI and water resilience; flood forecasting and management; game-theoretic water allocation; water-energy-food nexus; telematics and water informatics; remote sensing and hydrology; deep learning for rainfall prediction; digital twin of water systems
(This special issue belongs to the Section AI Systems: Theory and Applications)
Intelligent Cloud–Edge Networking: Innovations for Next-Gen Applications
edited by
submission deadline 7 Aug 2026 | Viewed by 291 | Submission Open
Keywords: cloud computing; edge computing; cloud– edge systems; network orchestration; distributed machine learning; scalable network architectures; network slicing; network security and privacy; next-generation applications; autonomous systems
(This special issue belongs to the Section AI in Autonomous Systems)
AI-Driven Multimodal Interfaces in XR: Enhancing Human–Computer Interaction submission deadline 14 Aug 2026 | Viewed by 1032 | Submission Open
Keywords: multimodal interfaces; extended reality (XR); artificial intelligence (AI); human– computer interaction (HCI); adaptive systems
(This special issue belongs to the Section AI in Autonomous Systems)
Generative AI Applications for Power Systems submission deadline 25 Aug 2026 | Viewed by 388 | Submission Open
Keywords: AI; generative AI; GANs; VAEs; transformers
(This special issue belongs to the Section AI in Autonomous Systems)
Leveraging Simulation and Deep Learning for Enhanced Health and Safety
edited by and
submission deadline 28 Aug 2026 | 3 articles | Viewed by 4122 | Submission Open
Keywords: deep learning; simulation-based modeling; AI safety; explainable AI (XAI); risk simulation; causal inference; computer vision; digital twins; safety-critical systems; property prediction
(This special issue belongs to the Section AI Systems: Theory and Applications)
The Application of Machine Learning and AI Technology Towards the Sustainable Development Goals
edited by
submission deadline 31 Aug 2026 | 5 articles | Viewed by 20145 | Submission Open
Keywords: artificial intelligence (AI) in sustainability; machine learning (ML) for sustainable development; smart cities and AI technologies; AI for environmental conservation; AI-driven renewable energy management; predictive analytics for SDGs; AI for climate change mitigation; AI in circular economy; AI for green transportation; AI in waste and water management
Application of Artificial Intelligence on Structures Subjected to Natural Hazards
edited by , Juan Bojórquez and
submission deadline 31 Aug 2026 | 1 articles | Viewed by 3304 | Submission Open
Keywords: earthquake engineering; seismic hazard; wind hazard; neural networks; metaheuristic techniques
Explainable and Trustworthy AI in Health and Biology: Enabling Transparent and Actionable Decision-Making
edited by Ahmed Salih
submission deadline 31 Aug 2026 | 2 articles | Viewed by 1702 | Submission Open
Keywords: explainable AI; trustworthy AI; model interpretability; responsible AI
(This special issue belongs to the Section Medical & Healthcare AI)
Advances in Artificial Intelligence and Emerging Machine Learning Applications
edited by Naveed Ilyas and Taqi Abrar
submission deadline 31 Aug 2026 | Viewed by 541 | Submission Open
Keywords: artificial intelligence; machine learning; deep learning; transformer networks; generative models; computer vision; medical image analysis; explainable AI; interdisciplinary applications; diffusion models
Smart Educational Technologies: Integrating AI, Robotics, and AR for 21st Century Learning
edited by and
submission deadline 31 Aug 2026 | Viewed by 320 | Submission Open
Keywords: artificial intelligence in education; technology-enhanced learning; computational thinking; educational robotics; learning analytics; personalized learning; augmented reality (AR) in education
Integrating Large Language Models into Robotic Autonomy submission deadline 31 Aug 2026 | Viewed by 268 | Submission Open
Keywords: LLMs in locomotion control; LLMs in navigation and semantic planning; LLMs in physical interaction and manipulation; voice-based control and communication; sensor-grounded perception; learning; real-time decision-making through voice and text commands; robot-to-human/robot-to-robot interaction; structured reasoning through multi-level representations
(This special issue belongs to the Section AI Systems: Theory and Applications)
Multi-Agent Modal Computing: Synergy, Scalability and Satellite-Earth Collaboration
edited by , and
submission deadline 31 Aug 2026 | Viewed by 259 | Submission Open
Keywords: multi-agent systems; multimodal learning; satellite computing; knowledge graph; edge AI; federated learning; remote sensing; distributed inference
Next-Generation Medical Imaging AI: Deep Learning Computer Vision with Multi-Task and Continual Learning
edited by and Tahir Mahmood
submission deadline 31 Aug 2026 | Viewed by 73 | Submission Open
Keywords: medical imaging; computer vision; deep learning; multi-task learning; continual learning; medical image segmentation; medical image classification; attention mechanisms; vision transformers; self-supervised learning; weakly supervised learning; domain adaptation; explainable AI; uncertainty estimation; clinical decision support
(This special issue belongs to the Section Medical & Healthcare AI)
Machine Learning-Augmented Optimization Methods for Energy and Infrastructure Systems
edited by , Chen Yang and Haoran Niu
submission deadline 31 Aug 2026 | Viewed by 48 | Submission Open
Keywords: machine learning-augmented optimization; learning-augmented algorithms; hybrid AI-optimization methods; energy system optimization; reinforcement learning for planning; critical infrastructure planning; robust and stochastic optimization; spatial and network optimization; digital twins for infrastructure systems; explainable AI for decision support
(This special issue belongs to the Section AI Systems: Theory and Applications)
Adaptive Control and Cognitive Architectures: Bridging Cybernetics, Neuroscience, and AI
edited by
submission deadline 18 Sep 2026 | Viewed by 212 | Submission Open
Keywords: adaptive control; cognitive architectures; cybernetics; neuroscience; artificial intelligence
(This special issue belongs to the Section AI Systems: Theory and Applications)
Responsible AI: Alignment, Decentralization, and Optimization in Multi-Agent Systems Across Dynamic Environments
edited by Chansoo Kim
submission deadline 23 Sep 2026 | 2 articles | Viewed by 1831 | Submission Open
Keywords: multi-agent systems; AI alignment and trustworthiness; AI ethical and social implications (ethical and societal dimensions); alignment with human values; decentralized and federated learning; optimization and AI; reinforcement and evolutionary learning; causal reasoning; robustness and adaptivity; dynamic environments; real-world AI applications and various applications such as physical AI (robotics); energy and battery; and finance and economics
(This special issue belongs to the Section AI Systems: Theory and Applications)
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