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Onco, Volume 4, Issue 2

2024 June - 5 articles

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Articles (5)

  • Review
  • Open Access
6 Citations
3,683 Views
15 Pages
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The Prognostic Role of Prognostic Nutritional Index and Controlling Nutritional Status in Predicting Survival in Older Adults with Oncological Disease: A Systematic Review

  • Ana Filipa Ferreira,
  • Tatiana Fernandes,
  • Maria do Carmo Carvalho and
  • Helena Soares Loureiro
Onco2024, 4(2), 101-115;https://doi.org/10.3390/onco4020009

2 June 2024

The increase in new cancer diagnoses in the elderly calls for new, accessible, and easy-to-use prognostic tools that contribute to lowering the burden of the disease. Recognising the importance of inflammation and nutritional status in the progressio...

Full Article
  • Review
  • Open Access
4 Citations
3,155 Views
14 Pages
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Can Tumour Antigens Act as Biomarkers for the Early Detection of Non-Small Cell Lung Cancer?

  • Eithar Mohamed,
  • Daniel Fletcher,
  • Simon Hart and
  • Barbara-ann Guinn
Onco2024, 4(2), 87-100;https://doi.org/10.3390/onco4020008

31 May 2024

Lung cancer (LC) is one of the leading causes of cancer-related deaths. Pulmonary nodules are one of the risk factors, and their discovery rate has been increasing due to enhanced performance of chest CT scans, but more than 90% are non-malignant, ca...

Full Article
  • Article
  • Open Access
2 Citations
2,415 Views
10 Pages
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Inhibitory Effects of Metformin for Pancreatic Neuroendocrine Neoplasms: Experimental Study on Mitochondrial Function

  • Shogo Maruzen,
  • Seiichi Munesue,
  • Mitsuyoshi Okazaki,
  • Satoshi Takada,
  • Shinichi Nakanuma,
  • Isamu Makino,
  • Linxiang Gong,
  • Susumu Kohno,
  • Chiaki Takahashi and
  • Shintaro Yagi
  • + 2 authors
Onco2024, 4(2), 77-86;https://doi.org/10.3390/onco4020007

27 April 2024

Although pancreatic neuroendocrine neoplasms (panNENs) are much less common and have a better prognosis than exocrine pancreatic cancers, their recurrence rate is not low, even in Grade 1 (World Health Organization classification) panNEN. Recently, t...

Full Article
  • Commentary
  • Open Access
2 Citations
2,245 Views
9 Pages
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How Reliable Are Predictions of CD8+ T Cell Epitope Recognition? Lessons for Cancer

  • Alexander A. Lehmann,
  • Paul V. Lehmann and
  • Stephen Todryk
Onco2024, 4(2), 68-76;https://doi.org/10.3390/onco4020006

17 April 2024

Synthetic peptides derived from antigen sequences are essential reagents for the detection of CD8+ cytotoxic T lymphocytes (CTLs), in assays such as ELISPOT/ImmunoSpot®. Indeed, the combination of peptides and ImmunoSpot® has been widely used...

Full Article
  • Article
  • Open Access
4 Citations
2,585 Views
12 Pages
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Deficiency in DNA Damage Repair Proteins Promotes Prostate Cancer Cell Migration through Oxidative Stress

  • Philippa Lantwin,
  • Adam Kaczorowski,
  • Cathleen Nientiedt,
  • Constantin Schwab,
  • Martina Kirchner,
  • Viktoria Schütz,
  • Magdalena Görtz,
  • Markus Hohenfellner,
  • Anette Duensing and
  • Stefan Duensing
  • + 1 author
Onco2024, 4(2), 56-67;https://doi.org/10.3390/onco4020005

28 March 2024

Introduction: DNA damage repair gene deficiency defines a subgroup of prostate cancer patients with early metastatic progression and unfavorable disease outcome. Whether deficiency in DNA damage repair genes directly promotes metastatic dissemination...

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