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Diabetology, Volume 5, Issue 2

2024 June - 7 articles

Cover Story: In our article, we debate the utility of reassessing the risk of foot complications in people with diabetes in a primary care setting. We found that at the two-year follow-up, less than 4% progress to a higher risk status according to the International Working Group on the Diabetic Foot classification. However, at the same time, there is a 2.6% regression, which may indicate concerns about the reliability of this classification. Our study supports the idea that foot risk reassessments can be every two years instead of yearly in this setting. View this paper
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Articles (7)

  • Article
  • Open Access
1 Citations
3,001 Views
11 Pages

Background: We assessed the pertinence of updating the International Working Group on the Diabetic Foot (IWGDF) risk classification yearly in people with diabetes by quantifying the changes in the risk group and its accuracy in identifying those deve...

  • Article
  • Open Access
2 Citations
3,164 Views
17 Pages

Diabetic foot complications constitute a large and rapidly growing global health problem, causing one million lower-extremity amputations annually. These amputations are typically preceded by preventable diabetic foot ulcers (DFUs). However, 80% of t...

  • Article
  • Open Access
4 Citations
8,017 Views
16 Pages

Prevalence of Peripheral Arterial Disease and Principal Associated Risk Factors in Patients with Type 2 Diabetes Mellitus: The IDON-Peripheral Arterial Disease Study

  • Aliyanet Isamara Porcayo Ascencio,
  • Evangelina Morales Carmona,
  • Jesús Morán Farías,
  • Dulce Stephanie Guzmán Medina,
  • Rebeca Galindo Salas and
  • Leobardo Sauque Reyna

The principal purpose of this study is to determine the prevalence of peripheral arterial disease (PAD), as well as the principal associated risk factors, in patients registered in the IDON-PAD database. PAD is a condition characterized by the narrow...

  • Article
  • Open Access
2,827 Views
12 Pages

Defining the miRnome of Saphenous Vein Smooth Muscle Cells from Patients with Type 2 Diabetes Mellitus

  • Alisah Hussain,
  • Yaw Asare-Amankwah,
  • Shehryar Qureshi,
  • M. Julie Thornton,
  • Timothy M. Palmer,
  • Israel O. Bolanle,
  • Ian C. Wood,
  • Neil A. Turner,
  • Karen E. Porter and
  • Kirsten Riches-Suman
  • + 1 author

Type 2 diabetes mellitus (T2DM) patients suffer premature development of cardiovascular disease and commonly require cardiac revascularization using the autologous saphenous vein (SV). Smooth muscle cells (SMCs) are the principal cell type within the...

  • Article
  • Open Access
2 Citations
2,306 Views
16 Pages

Do T2DM and Hyperglycaemia Affect the Expression Levels of the Regulating Enzymes of Cellular O-GlcNAcylation in Human Saphenous Vein Smooth Muscle Cells?

  • Israel O. Bolanle,
  • Gillian A. Durham,
  • James P. Hobkirk,
  • Mahmoud Loubani,
  • Roger G. Sturmey and
  • Timothy M. Palmer

25 April 2024

Protein O-GlcNAcylation, a dynamic and reversible glucose-dependent post-translational modification of serine and threonine residues on target proteins, has been proposed to promote vascular smooth muscle cell proliferation and migration events impli...

  • Article
  • Open Access
1 Citations
5,283 Views
11 Pages

Epidemiology of Diabetes Mellitus in Adults and Seniors in Rio Branco, Acre, Western Brazilian Amazon

  • Yara de Moura Magalhães Lima,
  • Fernanda Andrade Martins and
  • Alanderson Alves Ramalho

10 April 2024

(1) Background: To analyze the prevalence and factors associated with diabetes mellitus in adults and the elderly in Rio Branco, Acre, Western Brazilian Amazon. (2) Methods: The R software version 4.0.5 was used for estimating the prevalence of diabe...

  • Article
  • Open Access
20 Citations
14,915 Views
10 Pages

Burden of Infected Diabetic Foot Ulcers on Hospital Admissions and Costs in a Third-Level Center

  • Roberto Da Ros,
  • Roberta Assaloni,
  • Andrea Michelli,
  • Barbara Brunato,
  • Enrica Barro,
  • Marco Meloni and
  • Cesare Miranda

Diabetic foot is a common complication of diabetes that affects quality and prognosis of life for patients and often requires hospitalization. Infection, alone or in association with ischemia, is the main cause of hospital admission and impacts progn...

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Diabetology - ISSN 2673-4540