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Pathophysiology, Volume 29, Issue 2

2022 June - 11 articles

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Articles (11)

  • Article
  • Open Access
20 Citations
7,491 Views
7 Pages

Serum Ferritin in Metabolic Syndrome—Mechanisms and Clinical Applications

  • Shrey Kumar Srivastav,
  • Irfan Ahmad Mir,
  • Naman Bansal,
  • Pankaj Kumar Singh,
  • Rashmi Kumari and
  • Ajoy Deshmukh

Metabolic syndrome (MS) is a cluster of conditions including central obesity, hypertriglyceridemia, low HDL cholesterol, hyperglycaemia, and hypertension with a prevalence rate of 20–25% of the world’s adult population. Metabolic syndrome...

  • Review
  • Open Access
24 Citations
4,650 Views
21 Pages

Tuberculosis and Autoimmunity

  • Irina V. Belyaeva,
  • Anna N. Kosova and
  • Andrei G. Vasiliev

Tuberculosis remains a common and dangerous chronic bacterial infection worldwide. It is long-established that pathogenesis of many autoimmune diseases is mainly promoted by inadequate immune responses to bacterial agents, among them Mycobacterium tu...

  • Article
  • Open Access
5 Citations
3,540 Views
17 Pages

SARS-CoV-2-Induced Pathology—Relevance to COVID-19 Pathophysiology

  • Vsevolod A. Zinserling,
  • Natalia Yu Semenova,
  • Anastasia E. Bikmurzina,
  • Natalia M. Kruglova,
  • Oksana V. Rybalchenko and
  • Alexander G. Markov

In spite of intensive studies of different aspects of a new coronavirus infection, many issues still remain unclear. In a screening analysis of histopathology in l200 lethal cases, authors succeeded in performing a wide spectrum of immune histochemic...

  • Review
  • Open Access
18 Citations
11,074 Views
38 Pages

The Role of Exposomes in the Pathophysiology of Autoimmune Diseases II: Pathogens

  • Aristo Vojdani,
  • Elroy Vojdani,
  • Avi Z. Rosenberg and
  • Yehuda Shoenfeld

In our continuing examination of the role of exposomes in autoimmune disease, we use this review to focus on pathogens. Infections are major contributors to the pathophysiology of autoimmune diseases through various mechanisms, foremost being molecul...

  • Article
  • Open Access
5 Citations
3,023 Views
10 Pages

Platelet Distribution Width and Increased D-Dimer at Admission Predicts Subsequent Development of ARDS in COVID-19 Patients

  • Iviana P. Yovchevska,
  • Alexandar B. Trenovski,
  • Maria H. Atanasova,
  • Martin N. Georgiev,
  • Radka K. Tafradjiiska-Hadjiolova,
  • Simeon D. Lazarov and
  • Plamen H. Yovchevski

In the current pandemic of coronavirus disease (COVID-19), the identification of the patients admitted with severe infection–who are disposed to a high risk of acute respiratory distress syndrome (ARDS) development, is of a major significance f...

  • Article
  • Open Access
3 Citations
8,248 Views
10 Pages

Chronic Cannabis Intoxication and Propofol-Induced Salivation: Causes and Considerations

  • Allison Derise,
  • Carey Ford,
  • Nazar Hafiz,
  • Sudha Pandit,
  • Aditya Vyas,
  • Samuel Igbinedion,
  • James Morris,
  • Paul Jordan,
  • Qiang Cai and
  • Jonathan Steven Alexander

Legalization/decriminalization of cannabis will increase the numbers of patients who have had recent exposure to recreational or medical cannabis. Currently, little has been reported about potential interactions between cannabis use and Propofol anes...

  • Review
  • Open Access
18 Citations
8,276 Views
23 Pages

Metabolomics and EMT Markers of Breast Cancer: A Crosstalk and Future Perspective

  • Ajay Kumar Pal,
  • Prateek Sharma,
  • Alishan Zia,
  • Deepali Siwan,
  • Dipali Nandave,
  • Mukesh Nandave and
  • Rupesh K. Gautam

Cancer cells undergo transient EMT and MET phenomena or vice versa, along with the parallel interplay of various markers, often correlated as the determining factor in decoding metabolic profiling of breast cancers. Moreover, various cancer signaling...

  • Article
  • Open Access
14 Citations
6,349 Views
13 Pages

Chronic Fatigue Exhibits Heterogeneous Autoimmunity Characteristics Which Reflect Etiology

  • Olga V. Danilenko,
  • Natalia Y. Gavrilova and
  • Leonid P. Churilov

Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) is considered to be associated with post-viral complications and mental stress, but the role of autoimmunity also remains promising. A comparison of autoimmune profiles in chronic fatigue of...

  • Article
  • Open Access
4 Citations
3,090 Views
14 Pages

The Expression Level of ABCC6 Transporter in Colon Cancer Cells Correlates with the Activation of Different Intracellular Signaling Pathways

  • Vittorio Abruzzese,
  • Caecilia H. C. Sukowati,
  • Claudio Tiribelli,
  • Ilenia Matera,
  • Angela Ostuni and
  • Faustino Bisaccia

The ATP-binding cassette sub-family C member 6 transporter (ABCC6) is mainly found in the basolateral plasma membrane of hepatic and kidney cells. In hepatocarcinoma HepG2 cells, ABCC6 was involved in cell migration. In the present study, we investig...

  • Article
  • Open Access
1 Citations
3,431 Views
16 Pages

Transthoracic Echocardiography-Based Prediction Model of Adverse Event Risk in Patients with COVID-19

  • Elena Zelikovna Golukhova,
  • Inessa Viktorovna Slivneva,
  • Maxim Leonidovich Mamalyga,
  • Damir Ildarovich Marapov,
  • Mikhail Nikolaevich Alekhin,
  • Mikhail Mikhailovich Rybka and
  • Irina Vasilevna Volkovskaya

Cardiopulmonary disorders cause a significant increase in the risk of adverse events in patients with COVID-19. Therefore, the development of new diagnostic and treatment methods for comorbid disorders in COVID-19 patients is one of the main public h...

  • Article
  • Open Access
14 Citations
4,541 Views
14 Pages

Hsa-Mir-320c, Hsa-Mir-200c-3p, and Hsa-Mir-449c-5p as Potential Specific miRNA Biomarkers of COPD: A Pilot Study

  • Noemi Cerón-Pisa,
  • Amanda Iglesias,
  • Hanaa Shafiek,
  • Aina Martín-Medina,
  • Margalida Esteva-Socias,
  • Josep Muncunill,
  • Aarne Fleischer,
  • Javier Verdú,
  • Borja G. Cosío and
  • Jaume Sauleda

Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease commonly induced by cigarette smoke. The expression of miRNAs can be altered in patients with COPD and could be used as a biomarker. We aimed to identify a panel of miRNAs...

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Pathophysiology - ISSN 1873-149X