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8,508 Results Found

  • Review
  • Open Access
13 Citations
11,571 Views
18 Pages

27 April 2015

Total internal reflection fluorescence (TIRF) microscopy has been widely used as a single molecule imaging technique to study various fundamental aspects of cell biology, owing to its ability to selectively excite a very thin fluorescent volume immed...

  • Article
  • Open Access
7 Citations
3,232 Views
10 Pages

Surface Plasmon Resonance Microscopy Based on Total Internal Reflection

  • Teliang Zhang,
  • Xueliang Wang,
  • Youjun Zeng,
  • Songfeng Huang,
  • Xiaoqi Dai,
  • Weifu Kong,
  • Qian Liu,
  • Jiajie Chen,
  • Junle Qu and
  • Yonghong Shao

12 February 2023

Surface plasmon resonance microscopy (SPRM) has been widely employed in biological fields because of its high spatial resolution and label-free detection modality. In this study, SPRM based on total internal reflection (TIR) is studied via a home-bui...

  • Article
  • Open Access
38 Citations
6,058 Views
37 Pages

13 December 2020

The qualitative analysis of nanodiamonds by FTIR spectrometry as photoacoustic (FTIR–PAS), diffuse-reflectance (DRIFT), and attenuated total reflection (ATR) modalities was evaluated for rapid and nondestructive analysis and comparison of nanod...

  • Article
  • Open Access
5 Citations
2,053 Views
7 Pages

17 December 2022

Total internal reflection occurs at the interface between two media with different refractive indices during propagation of light rays from a medium with a higher refractive index to a medium with a lower refractive index. If the thickness of the sec...

  • Article
  • Open Access
30 Citations
4,194 Views
11 Pages

Quantitative Evaluation of Subsurface Damage by Improved Total Internal Reflection Microscopy

  • Kaizao Ni,
  • Xin Cheng,
  • Baoming Huang,
  • Shijie Liu,
  • Jianda Shao,
  • Zhouling Wu,
  • Jian Chen and
  • Ming Huang

1 May 2019

Subsurface damage (SSD), having a great impact on the laser-induced damage threshold (LIDT) of ultra-smooth optics applied in high-power laser systems, should be tightly controlled. An improved total internal reflection microscopy (TIRM), combined wi...

  • Article
  • Open Access
4 Citations
2,096 Views
16 Pages

16 February 2024

A spatial-frequency thin-film filter with inclusions of nanoparticles operating in the visible range of the spectrum is investigated. The effect of nanoparticles embedded in the central and lateral layers of the frustrated total internal reflection f...

  • Article
  • Open Access
11 Citations
3,614 Views
13 Pages

A Novel Fiber-Optic Ice Sensor to Identify Ice Types Based on Total Reflection

  • Chi Zhang,
  • Chunhua Xiao,
  • Shaorong Li,
  • Xiaowei Guo,
  • Qi Wang,
  • Yizhou He,
  • Huiyan Lv,
  • Hongkai Yan and
  • Dongan Liu

14 April 2023

To address the issues of not accurately identifying ice types and thickness in current fiber-optic ice sensors, in this paper, we design a novel fiber-optic ice sensor based on the reflected light intensity modulation method and total reflection prin...

  • Review
  • Open Access
25 Citations
6,594 Views
18 Pages

8 July 2020

Terahertz (THz) technique has become one of the most promising analytical methods and has been applied in many fields. Attenuated total reflection (ATR) technique applied in THz spectroscopy and imaging has been proven to be superior in functionaliti...

  • Article
  • Open Access
1 Citations
909 Views
18 Pages

Total Internal Reflection End-Pumped Solar Laser with the Solar-to-Laser Conversion Efficiency of 6.09%

  • Lin Wang,
  • Haiyang Zhang,
  • Dário Garcia,
  • Weichen Xu,
  • Changming Zhao and
  • Anran Guo

29 July 2025

A novel total internal reflection solar end-pumped laser system has been introduced for the first time, aimed at enhancing the solar-to-laser conversion efficiency. Utilizing a conical solid or cavity reflector, this system refocuses sunlight from a...

  • Letter
  • Open Access
5 Citations
4,309 Views
14 Pages

Critical Factors for In Vivo Measurements of Human Skin by Terahertz Attenuated Total Reflection Spectroscopy

  • Lixia Wang,
  • Sayon Guilavogui,
  • Henghui Yin,
  • Yiping Wu,
  • Xiaofei Zang,
  • Jingya Xie,
  • Li Ding and
  • Lin Chen

30 July 2020

Attenuated total reflection (ATR) geometry is a suitable choice for in vivo measurements of human skin due to the deep penetration of the field into the sample and since it makes it easy to measure the reference spectrum. On the other hand, there are...

  • Communication
  • Open Access
3 Citations
5,722 Views
9 Pages

Refractive index measurements have been an important task for a long time because that index plays an essential role in describing the optical properties of a material. Many methods have been developed to perform that task. Some of them use interfero...

  • Article
  • Open Access
4 Citations
4,784 Views
24 Pages

28 June 2024

To address the technical challenge of identifying tiny defects, especially dust and point defects, on mobile phone flat glass, an automatic optical inspection system is established. The system investigates algorithms including imaging principles, tar...

  • Article
  • Open Access
6 Citations
3,903 Views
8 Pages

22 March 2022

In this study, we demonstrate that drugs in plastic packaging can be identified without being opened using attenuated total reflection terahertz time domain spectroscopy. In this system, the terahertz wave undergoes total internal reflection at the i...

  • Review
  • Open Access
15 Citations
7,553 Views
21 Pages

A review with more than 100 references on the principles and recent developments in the solid-phase extraction (SPE) prior and for in situ near and attenuated total reflection (ATR) infrared spectroscopic analysis is presented. New materials, chromat...

  • Feature Paper
  • Article
  • Open Access
1 Citations
3,466 Views
11 Pages

Coherent Perfect Absorption in a Transparent Polymer Film on a Transparent Substrate Utilizing Total Internal Reflection by Grazing Incidence

  • Mayu Hasegawa,
  • Junpei Oi,
  • Kyohei Yamashita,
  • Keisuke Seto,
  • Takayoshi Kobayashi and
  • Eiji Tokunaga

3 April 2022

A simple scheme for single-channel coherent perfect absorption (CPA) of transparent materials is proposed and experimentally realized using total internal reflection by grazing incidence, with a single dielectric layer sandwiched by semi-infinite die...

  • Article
  • Open Access
91 Citations
12,154 Views
30 Pages

19 September 2021

This study aims to compare photoacoustic (FTIR–PAS), diffuse reflectance (DRIFT), and attenuated total reflection (ATR) FTIR modalities in the wide wavenumber range from NIR (7500 cm−1) to FIR (150 cm−1) for the same silicate soil samples under the s...

  • Article
  • Open Access
1 Citations
2,388 Views
15 Pages

4 November 2024

This study presents a significant advancement in LED interior lighting through the development and application of Asymmetric Lens–Total Internal Reflection (AL–TIR) optics, with a focus on enhancing lighting uniformity and indoor comfort...

  • Article
  • Open Access
9 Citations
3,820 Views
15 Pages

10 February 2023

We investigate the combined effects of surface diffraction and total internal reflection (TIR) in the design of 3-dimensional materials exhibiting distinct structural colour on various facets. We employ mechanical wrinkling to introduce surface diffr...

  • Article
  • Open Access
1,014 Views
10 Pages

Total internal reflection fluorescence–structured illumination microscopy (TIRF-SIM) can enhance the lateral resolution of fluorescence microscopy to twice the diffraction limit, enabling subtler observations of activity in subcellular life. Ho...

  • Article
  • Open Access
1 Citations
2,258 Views
19 Pages

24 October 2023

Many phenomena observed in synthetic and biological colloidal suspensions are dominated by the static interaction energies and the hydrodynamic interactions that act both between individual particles and also between colloids and macroscopic interfac...

  • Proceeding Paper
  • Open Access
953 Views
5 Pages

7 October 2023

The possibility of using mid-infrared (IR) spectroscopy in combination with the method of attenuated total reflection (ATR) to analyze the quality of dairy products is shown. The application of chemometrics, in particular the multivariate curve resol...

  • Article
  • Open Access
17 Citations
13,419 Views
13 Pages

14 April 2009

A small-displacement sensor based on total-internal reflection theory and surface plasmon resonance technology is proposed for use in heterodyne interferometry. A small displacement can be obtained simply by measuring the variation in phase differenc...

  • Communication
  • Open Access
6 Citations
3,001 Views
9 Pages

13 April 2021

Field-portable observation and analysis of particulate matter (PM) is required to enhance healthy lives. Various types of the PM measurement methods are in use; however, each of these methods has significant limitations in that real time measurement...

  • Article
  • Open Access
16 Citations
12,332 Views
21 Pages

28 January 2010

Electrostatic interactions between dielectric surfaces and different fluorophores used in ultrasensitive fluorescence microscopy are investigated using objective-based Total Internal Reflection Fluorescence Correlation Spectroscopy (TIR-FCS). The int...

  • Article
  • Open Access
2 Citations
3,298 Views
7 Pages

Label-Free Imaging of Single Nanoparticles Using Total Internal Reflection-Based Leakage Radiation Microscopy

  • Liwen Jiang,
  • Xuqing Sun,
  • Hongyao Liu,
  • Ruxue Wei,
  • Xue Wang,
  • Chang Wang,
  • Xinchao Lu and
  • Chengjun Huang

27 March 2020

Label-free, fast, and single nanoparticle detection is demanded for the in situ monitoring of nano-pollutants in the environment, which have potential toxic effects on human health. We present the label-free imaging of single nanoparticles by using t...

  • Article
  • Open Access
1 Citations
3,376 Views
20 Pages

Insulin-Mimetic Activity of Herbal Extracts Identified with Large-Scale Total Internal Reflection Fluorescence Microscopy

  • Cathrina Neuhauser,
  • Bettina Schwarzinger,
  • Clemens Schwarzinger,
  • Michaela Feichtinger,
  • Verena Stadlbauer,
  • Verena Arnaut,
  • Ivana Drotarova,
  • Bernhard Blank-Landeshammer and
  • Julian Weghuber

9 July 2024

Diabetes mellitus is a spreading global pandemic. Type 2 diabetes mellitus (T2DM) is the predominant form of diabetes, in which a reduction in blood glucose uptake is caused by impaired glucose transporter 4 (GLUT4) translocation to the plasma membra...

  • Article
  • Open Access
1,660 Views
15 Pages

26 June 2025

During the manufacturing of precision optical elements, subsurface defects seriously affect the performance of the elements, leading to the enhancement of light fields, an increase in laser absorption and an decrease in mechanical properties. It has...

  • Article
  • Open Access
8 Citations
3,355 Views
17 Pages

6 July 2019

Traditional compensation methods based on temperature-related parameters are not effective for complex total reflection prism laser gyro (TRPLG) bias variation. Because the high frequency oscillator voltage (UHFO) fundamentally affects the TRPLG bias...

  • Article
  • Open Access
9 Citations
5,320 Views
10 Pages

Fast Focal Point Correction in Prism-Coupled Total Internal Reflection Scanning Imager Using an Electronically Tunable Lens

  • Chenggang Zhu,
  • Bilin Ge,
  • Ru Chen,
  • Xiangdong Zhu,
  • Lan Mi,
  • Jiong Ma,
  • Xu Wang,
  • Fengyun Zheng and
  • Yiyan Fei

9 February 2018

Total internal reflection (TIR) is useful for interrogating physical and chemical processes that occur at the interface between two transparent media. Yet prism-coupled TIR imaging microscopes suffer from limited sensing areas due to the fact that th...

  • Article
  • Open Access
12 Citations
4,125 Views
14 Pages

Fatty Acid Prediction in Bovine Milk by Attenuated Total Reflection Infrared Spectroscopy after Solvent-Free Lipid Separation

  • Christopher Karim Akhgar,
  • Vanessa Nürnberger,
  • Marlene Nadvornik,
  • Margit Velik,
  • Andreas Schwaighofer,
  • Erwin Rosenberg and
  • Bernhard Lendl

11 May 2021

In the present study, a novel approach for mid-infrared (IR)-based prediction of bovine milk fatty acid composition is introduced. A rapid, solvent-free, two-step centrifugation method was applied in order to obtain representative milk fat fractions....

  • Article
  • Open Access
9 Citations
5,526 Views
26 Pages

6 May 2015

Total-reflection X-ray fluorescence (TXRF) has achieved remarkable success with the advantages of simultaneous multi-element analysis capability, decreased background noise, no matrix effects, wide dynamic range, ease of operation, and potential of t...

  • Article
  • Open Access
51 Citations
6,195 Views
13 Pages

13 June 2019

Due to the existence of Lingzhi adulteration, there is a growing demand for species classification of medicinal mushrooms by various techniques. The objective of this study was to explore a rapid and reliable way to distinguish between different Ling...

  • Article
  • Open Access
7 Citations
4,315 Views
22 Pages

Microfabrication Process Development for a Polymer-Based Lab-on-Chip Concept Applied in Attenuated Total Reflection Fourier Transform Infrared Spectroelectrochemistry

  • Noah Atkinson,
  • Tyler A. Morhart,
  • Garth Wells,
  • Grace T. Flaman,
  • Eric Petro,
  • Stuart Read,
  • Scott M. Rosendahl,
  • Ian J. Burgess and
  • Sven Achenbach

8 July 2023

Micro electro-mechanical systems (MEMS) combining sensing and microfluidics functionalities, as are common in Lab-on-Chip (LoC) devices, are increasingly based on polymers. Benefits of polymers include tunable material properties, the possibility of...

  • Article
  • Open Access
12 Citations
5,994 Views
17 Pages

Determination of Volatile Organic Compounds in Water by Attenuated Total Reflection Infrared Spectroscopy and Diamond-Like Carbon Coated Silicon Wafers

  • Carina Dettenrieder,
  • Dervis Türkmen,
  • Andreas Mattsson,
  • Lars Österlund,
  • Mikael Karlsson and
  • Boris Mizaikoff

Volatile organic compounds (VOCs) are one of the most commonly detected contaminants in water. The occurrence is mainly in gasoline and other petroleum-based products, fumigants, paints and plastics. Releases into the environment and the widespread u...

  • Communication
  • Open Access
8 Citations
2,384 Views
10 Pages

Total Internal Reflection Ellipsometry Approach for Bloch Surface Waves Biosensing Applications

  • Ernesta Bužavaitė-Vertelienė,
  • Vincentas Maciulis,
  • Justina Anulytė,
  • Tomas Tolenis,
  • Algirdas Baskys,
  • Ieva Plikusiene and
  • Zigmas Balevičius

30 July 2022

A one-dimensional photonic crystal with an additional TiO2 layer, supporting Bloch surface waves (BSW), was used for enhanced signal sensitivity for the detection of protein interaction. To compare the optical response of BSW and photonic crystals (P...

  • Article
  • Open Access
1 Citations
2,229 Views
19 Pages

Renal Cell Carcinoma Discrimination through Attenuated Total Reflection Fourier Transform Infrared Spectroscopy of Dried Human Urine and Machine Learning Techniques

  • Bogdan Adrian Buhas,
  • Lucia Ana-Maria Muntean,
  • Guillaume Ploussard,
  • Bogdan Ovidiu Feciche,
  • Iulia Andras,
  • Valentin Toma,
  • Teodor Andrei Maghiar,
  • Nicolae Crișan,
  • Rareș-Ionuț Știufiuc and
  • Constantin Mihai Lucaciu

11 September 2024

Renal cell carcinoma (RCC) is the sixth most common cancer in men and is often asymptomatic, leading to incidental detection in advanced disease stages that are associated with aggressive histology and poorer outcomes. Various cancer biomarkers are f...

  • Article
  • Open Access
5 Citations
4,354 Views
23 Pages

17 October 2023

This paper presents a preliminary scientific investigation of pigments used by Martiros Sarian, a prominent Armenian artist known for his vibrant and evocative paintings. The study focuses on five of Sarian’s paintings from different periods of...

  • Article
  • Open Access
1 Citations
1,042 Views
20 Pages

In this paper, we experimentally investigated the excitation of spoof surface plasmon polaritons (SSPPs) supported by a 1D subwavelength grating with a rectangular profile in the terahertz (THz) frequency range. Using the attenuated total reflection...

  • Concept Paper
  • Open Access
18 Citations
5,206 Views
20 Pages

Attenuated Total Reflection at THz Wavelengths: Prospective Use of Total Internal Reflection and Polariscopy

  • Meguya Ryu,
  • Soon Hock Ng,
  • Vijayakumar Anand,
  • Stefan Lundgaard,
  • Jingwen Hu,
  • Tomas Katkus,
  • Dominique Appadoo,
  • Zoltan Vilagosh,
  • Andrew W. Wood and
  • Junko Morikawa
  • + 1 author

19 August 2021

Capabilities of the attenuated total reflection (ATR) at THz wavelengths for increased sub-surface depth characterisation of (bio-)materials are presented. The penetration depth of a THz evanescent wave in biological samples is dependent on the wavel...

  • Article
  • Open Access
19 Citations
4,010 Views
12 Pages

Investigation and Comparison of Specific Antibodies’ Affinity Interaction with SARS-CoV-2 Wild-Type, B.1.1.7, and B.1.351 Spike Protein by Total Internal Reflection Ellipsometry

  • Ieva Plikusiene,
  • Vincentas Maciulis,
  • Silvija Juciute,
  • Ruta Maciuleviciene,
  • Saulius Balevicius,
  • Arunas Ramanavicius and
  • Almira Ramanaviciene

18 May 2022

SARS-CoV-2 vaccines provide strong protection against COVID-19. However, the emergence of SARS-CoV-2 variants has raised concerns about the efficacy of vaccines. In this study, we investigated the interactions of specific polyclonal human antibodies...

  • Article
  • Open Access
1 Citations
5,769 Views
12 Pages

7 August 2015

Using the beam propagation method, an analytical expression of the reflection spectra of a Kretschmann configuration is derived in order to excite hybridized surface plasmonic polaritons (HSPPs). In this configuration, the cladding is a uniaxial diel...

  • Article
  • Open Access
7 Citations
4,775 Views
8 Pages

Corrosion Detection by Infrared Attenuated Total Reflection Spectroscopy via Diamond-Like Carbon-Coated Silicon Wafers and Iron-Sensitive Dyes

  • Dervis Türkmen,
  • Carina Dettenrieder,
  • Pontus Forsberg,
  • Andreas Mattsson,
  • Fredrik Nikolajeff,
  • Lars Österlund,
  • Mikael Karlsson and
  • Boris Mizaikoff

1 August 2019

The durability of metal-based constructions, especially those containing reinforced concrete, is mainly limited by corrosion processes. Diamond-like carbon (DLC)-coated silicon (Si) wafers provide a chemically inert and mechanically robust sensing in...

  • Article
  • Open Access
1 Citations
1,457 Views
15 Pages

Sex-Dependent Differences in the Elemental Composition of Internal Organs Determined via Total Reflection X-Ray Fluorescence and Inductively Coupled Plasma Optical Emission Spectroscopy

  • Aleksandra Wilk,
  • Zuzanna Setkowicz,
  • Katarzyna Matusiak,
  • Eva Margui Grabulosa,
  • Marzena Rugiel,
  • Paula Kasprzyk,
  • Agnieszka Drozdz and
  • Joanna Chwiej

Background: Research on elemental changes in tissues and organs provides valuable information enabling better understanding of the physiological processes occurring in a living organism, as well as the pathogenesis and course of various diseases. The...

  • Feature Paper
  • Article
  • Open Access
10 Citations
4,926 Views
12 Pages

Characterisation of Biological Materials at THz Frequencies by Attenuated Total Reflection: Lard

  • Zoltan Vilagosh,
  • Alireza Lajevardipour,
  • Dominique Appadoo,
  • Soon Hock Ng,
  • Saulius Juodkazis and
  • Andrew W. Wood

4 December 2020

The penetration depth of an evanescent wave in Attenuated Total Reflection (ATR) is dependent on the wavelength of the radiation utilised. At THz frequencies, the penetration depth into biological tissues is in the order of 0.1 to 0.5 mm; rendered pi...

  • Article
  • Open Access
2 Citations
1,975 Views
9 Pages

6 October 2022

Small and compact mid-infrared devices are of increasing importance, as there are several applications demanding on-site and real-time measurements in harsh real-world scenarios. The RobustATR, an innovative infrared attenuated total reflectance (IR-...

  • Communication
  • Open Access
3 Citations
3,958 Views
10 Pages

Total Internal Reflection Lens for Optical Wireless Receivers

  • René Kirrbach,
  • Tobias Schneider,
  • Mira Stephan,
  • Alexander Noack,
  • Michael Faulwaßer and
  • Frank Deicke

This work considers the use of a freeform total internal reflection (TIR) lens for optical concentration and provides for the first time experimental results in the context of optical wireless communications (OWC). The lens is placed on a surface-mou...

  • Article
  • Open Access
584 Views
15 Pages

16 October 2025

Indirect lighting systems employing light-emitting diodes (LEDs) and diffuse reflective surfaces are prevalent in applications demanding stringent illumination uniformity. However, conventional diffuse reflection approaches exhibit inherent limitatio...

  • Article
  • Open Access
6 Citations
3,343 Views
14 Pages

Grape marc spirits, such as the Greek tsipouro/tsikoudia, reflect the cultural heritage of winemaking traditions worldwide. This study explored the application of Attenuated Total Reflectance–Fourier Transform Infrared (ATR-FTIR) spectroscopy c...

  • Review
  • Open Access
3 Citations
3,307 Views
30 Pages

26 January 2025

This paper briefly overviews the application of total-reflection X-ray fluorescence (TXRF) spectrometry in the biosciences, focusing on key bioanalytical applications. It seeks to review and update the current state of TXRF’s use in biomedical,...

  • Article
  • Open Access
2 Citations
2,718 Views
12 Pages

Solvent-Free Lipid Separation and Attenuated Total Reflectance Infrared Spectroscopy for Fast and Green Fatty Acid Profiling of Human Milk

  • Christopher Karim Akhgar,
  • Victoria Ramos-Garcia,
  • Vanessa Nürnberger,
  • Alba Moreno-Giménez,
  • Julia Kuligowski,
  • Erwin Rosenberg,
  • Andreas Schwaighofer and
  • Bernhard Lendl

3 December 2022

This study presents the first mid-infrared (IR)-based method capable of simultaneously predicting concentrations of individual fatty acids (FAs) and relevant sum parameters in human milk (HM). Representative fat fractions of 50 HM samples were obtain...

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