Sign in to use this feature.

Years

Between: -

Subjects

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Journals

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Article Types

Countries / Regions

remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline
remove_circle_outline

Search Results (4,669)

Search Parameters:
Keywords = stage of evolution

Order results
Result details
Results per page
Select all
Export citation of selected articles as:
13 pages, 1630 KB  
Article
Phylogenetic Structure Analysis Based on the Blue-Light Receptor Cryptochrome: Insights into How Light Shapes the Vertical Structure of Subtropical Forest Community
by Qiming Mei, Zhibin Chen, Yanshan Tan, Shuxiong Lai, Zefang Zhang, Zhengfeng Wang, Honglin Cao and Juyu Lian
Forests 2025, 16(11), 1673; https://doi.org/10.3390/f16111673 (registering DOI) - 2 Nov 2025
Abstract
Understanding the mechanisms that assemble diverse forest communities is a central goal in ecology. Phylogenetic analyses based on DNA barcodes have advanced this field, but their use of sequences evolving at constant rates may not capture adaptations to specific environmental drivers. Light is [...] Read more.
Understanding the mechanisms that assemble diverse forest communities is a central goal in ecology. Phylogenetic analyses based on DNA barcodes have advanced this field, but their use of sequences evolving at constant rates may not capture adaptations to specific environmental drivers. Light is a critical factor shaping forest structure, particularly in the vertical dimension. This study introduces a novel phylogenetic approach using the blue-light receptor gene, cryptochrome (Cry), which is directly involved in plant light perception and adaptation. We reconstructed a Cry-based phylogeny for 96 tree species in a 20 ha subtropical forest dynamics plot and analyzed community structure using the net relatedness index (NRI) and nearest taxon index (NTI) across horizontal habitats, successional stages, and vertical canopy layers. Compared to traditional DNA barcoding, the Cry phylogeny revealed distinct patterns, showing consistent phylogenetic structure across different habitats—a finding indicative of convergent evolution in light-sensing systems. Furthermore, the Cry-based analysis demonstrated a stronger and more consistent signal in the forest’s vertical structure, with significant phylogenetic clustering in upper canopy layers, directly linking light adaptation to community stratification. Over time, both NRI and NTI values increased, suggesting succession leads to greater phylogenetic overdispersion and highlighting an increased role for environmental filtering among closely related taxa. Our results validate Cry as a powerful functional gene marker for phylogenetics, providing unique insights into how light environment filters species and shapes the vertical assembly of forest communities. Full article
(This article belongs to the Section Genetics and Molecular Biology)
Show Figures

Figure 1

14 pages, 5309 KB  
Article
Bimodal Microstructure and Strengthening Mechanisms of a Mg-RE Alloy Processed by Asymmetric Upsetting–Extrusion
by Nanjiang Chen, Bingchun Jiang, Yuze Xi, Lei Jing, Liwei Lu and Yiquan Li
Materials 2025, 18(21), 5001; https://doi.org/10.3390/ma18215001 (registering DOI) - 1 Nov 2025
Abstract
This study successfully produced a magnesium alloy bar featuring a bimodal microstructure with high strength via an asymmetric upsetting–extrusion process. The evolution of microstructure, texture, and mechanical properties was systematically investigated using finite element simulation, room-temperature tensile tests, optical microscopy, scanning electron microscopy, [...] Read more.
This study successfully produced a magnesium alloy bar featuring a bimodal microstructure with high strength via an asymmetric upsetting–extrusion process. The evolution of microstructure, texture, and mechanical properties was systematically investigated using finite element simulation, room-temperature tensile tests, optical microscopy, scanning electron microscopy, and electron backscatter diffraction. Results demonstrate that the bimodal structure forms under the combined effects of shear deformation in the upsetting stage and low-speed, high-ratio deformation in the extrusion stage. This structure consists of coarse deformed grains containing high-density dislocations surrounded by fine dynamically recrystallized grains. A strong <10-10>//ED basal fiber texture also developed, which effectively suppresses basal slip. Continuous dynamic recrystallization was the primary grain refinement mechanism. The 370 °C extruded alloy achieved a high tensile strength of 457.9 MPa, but its elongation was limited to 3.96%. This combination of strength and ductility is attributed to the synergistic influence of the bimodal microstructure, strong basal texture, and high dislocation density. Full article
(This article belongs to the Section Metals and Alloys)
Show Figures

Figure 1

19 pages, 893 KB  
Review
Beyond the Sleep Lab: A Narrative Review of Wearable Sleep Monitoring
by Maria P. Mogavero, Giuseppe Lanza, Oliviero Bruni, Luigi Ferini-Strambi, Alessandro Silvani, Ugo Faraguna and Raffaele Ferri
Bioengineering 2025, 12(11), 1191; https://doi.org/10.3390/bioengineering12111191 (registering DOI) - 31 Oct 2025
Abstract
Sleep is a fundamental biological process essential for health and homeostasis. Traditionally investigated through laboratory-based polysomnography (PSG), sleep research has undergone a paradigm shift with the advent of wearable technologies that enable non-invasive, long-term, and real-world monitoring. This review traces the evolution from [...] Read more.
Sleep is a fundamental biological process essential for health and homeostasis. Traditionally investigated through laboratory-based polysomnography (PSG), sleep research has undergone a paradigm shift with the advent of wearable technologies that enable non-invasive, long-term, and real-world monitoring. This review traces the evolution from early analog and actigraphic methods to current multi-sensor and AI-driven wearable systems. We summarize major technological milestones, including the transition from movement-based to physiological and biochemical sensing, and the growing role of edge computing and deep learning in automated sleep staging. Comparative studies with PSG are discussed, alongside the strengths and limitations of emerging devices such as wristbands, rings, headbands, and camera-based systems. The clinical applications of wearable sleep monitors are examined in relation to remote patient management, personalized medicine, and large-scale population research. Finally, we outline future directions toward integrating multimodal biosensing, transparent algorithms, and standardized validation frameworks. By bridging laboratory precision with ecological validity, wearable technologies promise to redefine the gold standard for sleep monitoring, advancing both individualized care and population-level health assessment. Full article
(This article belongs to the Section Biosignal Processing)
35 pages, 37988 KB  
Article
Shock Mach Number Effect on Instability Evolution at a Light–Heavy Fluid Interface: A Numerical Investigation
by Salman Saud Alsaeed, Satyvir Singh and Nahar F. Alshammari
Axioms 2025, 14(11), 813; https://doi.org/10.3390/axioms14110813 (registering DOI) - 31 Oct 2025
Abstract
Shock–accelerated interfaces between fluids of different densities are prone to Richtmyer–Meshkov-type instabilities, whose evolution is strongly influenced by the incident shock Mach number. In this study, we present a systematic numerical investigation of the Mach number effect on the instability growth at a [...] Read more.
Shock–accelerated interfaces between fluids of different densities are prone to Richtmyer–Meshkov-type instabilities, whose evolution is strongly influenced by the incident shock Mach number. In this study, we present a systematic numerical investigation of the Mach number effect on the instability growth at a light–heavy fluid layer. The governing dynamics are modeled using the compressible multi-species Euler equations, and the simulations are performed with a high-order modal discontinuous Galerkin method. This approach provides accurate resolution of sharp interfaces, shock waves, and small-scale vortical structures. A series of two-dimensional simulations is carried out for a range of shock Mach numbers impinging on a sinusoidally perturbed light–heavy fluid interface. The results highlight the distinct stages of instability evolution, from shock–interface interaction and baroclinic vorticity deposition to nonlinear roll-up and interface deformation. Quantitative diagnostics—including circulation, enstrophy, vorticity extrema, and mixing width—are employed to characterize the instability dynamics and to isolate the role of Mach number in enhancing or suppressing growth. Particular attention is given to the mechanisms of vorticity generation through baroclinic torque and compressibility effects. Moreover, the analysis of controlling parameters, including Atwood number, layer thickness, and initial perturbation amplitude, broadens the parametric understanding of shock-driven instabilities. The results reveal that increasing shock Mach number markedly enhances vorticity generation and accelerates interface growth, while the resulting nonlinear morphology remains strongly sensitive to variations in Atwood number and perturbation amplitude. Full article
(This article belongs to the Special Issue Applied Mathematics and Mathematical Modeling)
19 pages, 2888 KB  
Article
Pyrolysis Characteristics and Reaction Mechanism of Cement Fiberboard with Thermogravimetry/Fourier Transform Infrared Analysis
by Yuxiang Zhu, Longjiang Tang, Ying Hu, Chunlin Yang, Weijian Deng and Yanming Ding
Fire 2025, 8(11), 426; https://doi.org/10.3390/fire8110426 (registering DOI) - 31 Oct 2025
Abstract
In this study, thermogravimetric analysis (TGA) was coupled with Fourier-transform infrared (FTIR) spectroscopy to systematically investigate the pyrolysis characteristics and mechanisms of cement fiberboard across varying heating rates. Experimental findings demonstrated that the thermal degradation process occurs in four distinct phases. Overlapping decomposition [...] Read more.
In this study, thermogravimetric analysis (TGA) was coupled with Fourier-transform infrared (FTIR) spectroscopy to systematically investigate the pyrolysis characteristics and mechanisms of cement fiberboard across varying heating rates. Experimental findings demonstrated that the thermal degradation process occurs in four distinct phases. Overlapping decomposition peaks in DTG curves were successfully resolved using a double-Gaussian deconvolution algorithm. A comprehensive kinetic analysis was conducted by integrating model-free iso-conversional methods (Flynn–Wall–Ozawa and Kissinger–Akahira–Sunose analysis) with a model-fitting technique (Coats–Redfern approximation) to determine the activation energies for each degradation stage. A subsequent FTIR spectroscopic analysis revealed that the evolution of gaseous products follows the sequence CO2 > H2O > CH4. The CO2 release was found to originate from multiple pathways, including the decomposition of organic components and high-temperature inorganic reactions. Notably, while the heating rate had a negligible impact on product speciation, it exhibited a statistically significant influence on CO2 emission intensities. Finally, mechanistic interpretations integrating Arrhenius parameters with time-resolved infrared spectral features were proposed for each thermal decomposition stage. Full article
Show Figures

Figure 1

14 pages, 1585 KB  
Article
Automated Nonlinear Acoustics System for Real-Time Monitoring of Cement-Based Composites
by Theodoti Z. Kordatou, Dimitrios A. Exarchos and Theodore E. Matikas
Sensors 2025, 25(21), 6655; https://doi.org/10.3390/s25216655 (registering DOI) - 31 Oct 2025
Abstract
The development of automated systems for real-time material evaluation is becoming increasingly critical for structural engineering applications, infrastructure diagnostics and advanced material research. This work introduces a novel, fully automated nonlinear acoustics monitoring platform that employs Bulk Wave excitation in combination with non-contact [...] Read more.
The development of automated systems for real-time material evaluation is becoming increasingly critical for structural engineering applications, infrastructure diagnostics and advanced material research. This work introduces a novel, fully automated nonlinear acoustics monitoring platform that employs Bulk Wave excitation in combination with non-contact Laser Doppler Vibrometry (LDV) detection to continuously assess the microstructural evolution of cement-based composites. Unlike conventional approaches—such as ultrasonic velocity measurements or compressive strength tests—which lack sensitivity to early-stage changes and also require manual operation, the proposed system enables unsupervised, high-precision monitoring of the material by leveraging the second and third harmonic generation (β2, β3) as nonlinear indicators of internal material changes. A specialized LabVIEW-based software manages excitation control, signal acquisition, frequency-domain analysis, and real-time feedback. As an initial step, the system’s stability, linearity, and measurement reliability were validated on metallic samples, and verified through long-duration experiments. Subsequently, the system was used to monitor hydration in cement-based specimens with varying water-to-cement and carbon nanotube (CNT) reinforcement ratios, thereby demonstrating its capability to resolve subtle nonlinear responses. The results highlight the system’s enhanced sensitivity, repeatability, and scalability, demonstrating that it as a powerful tool for structural health monitoring, smart infrastructure, and predictive maintenance applications. Full article
Show Figures

Figure 1

36 pages, 2782 KB  
Systematic Review
Framework, Implementation, and User Experience Aspects of Driver Monitoring: A Systematic Review
by Luis A. Salazar-Calderón, Sergio Alberto Navarro-Tuch and Javier Izquierdo-Reyes
Appl. Sci. 2025, 15(21), 11638; https://doi.org/10.3390/app152111638 (registering DOI) - 31 Oct 2025
Viewed by 20
Abstract
Driver monitoring systems (DMS), advanced driver assistance ssystems (ADAs), and technologies for autonomous driving, along with other upcoming innovations, have been developed as possible solutions to minimize accidents resulting from human error. This paper presents a thorough review of DMSs and user experience [...] Read more.
Driver monitoring systems (DMS), advanced driver assistance ssystems (ADAs), and technologies for autonomous driving, along with other upcoming innovations, have been developed as possible solutions to minimize accidents resulting from human error. This paper presents a thorough review of DMSs and user experience (UX). The objective is to investigate, combine, and evaluate the key elements involved in the development and application of DMSs, as well as the UX factors relevant to the current landscape of the field, serving as a reference for future investigations. The review encompasses a bibliographic analysis performed at different stages, offering valuable insights into the evolution of the topic. It examines the processes of development and implementation of driver monitoring systems. Furthermore, this work facilitates future research by consolidating and presenting a valuable collection of identified datasets, both public and private, for various research purposes. From this evaluation, critical components for DMSs can be identified, establishing a foundation for future research by providing a framework for the adoption and integration of these systems. Full article
(This article belongs to the Special Issue Advanced Technologies and Applications of Emotion Recognition)
Show Figures

Figure 1

21 pages, 14113 KB  
Article
Microstructure and Properties of Sm2O3 Micro-Dispersed Tungsten-Based Alloy and Its Sintering Evolution
by Song Ye, Ping Wang, Zhiqiang Cui, Ningfei Zhang, Yuhao Wang and Zhenyi Huang
Materials 2025, 18(21), 4973; https://doi.org/10.3390/ma18214973 (registering DOI) - 31 Oct 2025
Viewed by 126
Abstract
Tungsten (W) is regarded as the most promising plasma-facing material in thermonuclear fusion reactors due to its excellent properties, such as high strength, a high melting point, and a low sputtering rate. However, its low-temperature brittleness, recrystallization embrittlement, and irradiation embrittlement seriously limit [...] Read more.
Tungsten (W) is regarded as the most promising plasma-facing material in thermonuclear fusion reactors due to its excellent properties, such as high strength, a high melting point, and a low sputtering rate. However, its low-temperature brittleness, recrystallization embrittlement, and irradiation embrittlement seriously limit the practical application of W. In this research, the properties of tungsten-based materials were improved by introducing second phases into W. Core–shell composite powders with W particles as core and Sm(OH)3 thin films as shell were prepared by electroless plating, and sintered by spark plasma sintering (SPS) to obtain bulk. After sintering, the Sm(OH)3 shell transformed into the Sm2O3 phase with a different size, mainly distributed at W grain boundaries. The average size of W grains in the composite material was smaller than that of pure W sintered bulk due to the pinning of W grain boundaries by Sm2O3, while the porosity of the composite is reduced. Compared with pure W sintered bulk, the composites exhibited better mechanical properties and radiation resistance; although the thermal conductivity decreased somewhat, it still maintained a high level. With the increase in sintering temperature and pressure, the evolution of core–shell powders during the sintering process could be simplified into six stages, which occurred approximately in sequence. Full article
(This article belongs to the Section Metals and Alloys)
Show Figures

Graphical abstract

15 pages, 1965 KB  
Article
Influence of Diabetes on Expression of Ezrin and MMP-2 in Gingival Tissue of Patients with Periodontal Disease
by Ionut Catalin Botezatu, Maria Luiza Baean, Maria-Alexandra Martu, Ana Emanuela Botez, Cristina Daniela Dimitriu, Carmen Solcan, Anca Ileana Sin, Claudiu Topoliceanu, Elena-Carmen Cotrutz and Oana Elena Ciurcanu
J. Mol. Pathol. 2025, 6(4), 26; https://doi.org/10.3390/jmp6040026 - 31 Oct 2025
Viewed by 65
Abstract
Background: The aim of this study was to determine Ezrin and MMP-2 immunohistochemical expressions in the gingival tissue of patients with or without diabetes and to determine the role of the molecular pattern involvement in the evolution of periodontal disease. Material and Methods: [...] Read more.
Background: The aim of this study was to determine Ezrin and MMP-2 immunohistochemical expressions in the gingival tissue of patients with or without diabetes and to determine the role of the molecular pattern involvement in the evolution of periodontal disease. Material and Methods: In this histological study, we investigated 53 subjects with periodontal disease (test group—27 patients with type 2 DM; control—26 patients without diabetes). Samples from both groups were subjected to the immunohistochemistry (IHC) technique to evaluate the immunoreactivity (IR) intensity of Ezrin and MMP-2. Results: Among diabetic patients with periodontitis, 55.4% of patients exhibited intensely positive expression (+++) of Ezrin, and 44.6% of patients showed moderate expression (++) of Ezrin. All patients with diabetes and periodontitis showed intensely positive expression for MMP-2. In contrast, the control group showed negative expressions of Ezrin and MMP-2 (-) in 100% of cases. Significant statistical differences were found between Ezrin and MMP-2 expression in gingival samples of diabetic patients and non-diabetic patients with periodontal disease (p < 0.05). Conclusions: Ezrin and MMP-2 are significantly overexpressed in patients with diabetes and stage 2–3 periodontitis compared with non-diabetic patients with periodontal disease. Ezrin showed an exclusive pattern of moderate to strong positive staining in the diabetes–periodontitis group and complete absence in controls. MMP-2 displayed a broader range of staining intensities, with a predominance of strong positivity in all locations. Ezrin may represent a more consistent discriminative marker, whereas MMP-2 reflects a wider spectrum of tissue activation related to inflammation and tissue remodeling. Full article
Show Figures

Figure 1

26 pages, 24668 KB  
Article
Characteristics of the Main Controlling Factors and Formation–Evolution Process of Karst Collapse Columns in the Hancheng Mining Area, Northern China
by Yingtao Chen, Xufeng Yang, Huan Zhang, Gelian Dai, Shoutao Luo and Wenxin Yu
Water 2025, 17(21), 3112; https://doi.org/10.3390/w17213112 - 30 Oct 2025
Viewed by 190
Abstract
Karst collapse columns (KCCs) represent key concealed hazard-inducing factors that threaten the safety of coal mines in North China. To clarify their primary controlling geological factors and evolutionary processes, this study focuses on KCCs in the Hancheng Mining Area, situated on the southeastern [...] Read more.
Karst collapse columns (KCCs) represent key concealed hazard-inducing factors that threaten the safety of coal mines in North China. To clarify their primary controlling geological factors and evolutionary processes, this study focuses on KCCs in the Hancheng Mining Area, situated on the southeastern margin of the Ordos Basin, China. A comprehensive methodological approach—integrating field surveys, petrographic and mineralogical identification, geochemical analysis, and structural interpretation—was employed to investigate the dominant factors controlling KCC development and their evolutionary mechanisms. The results indicate the following: (1) Thick-bedded dolomites of the 5th Member of the Majiagou Formation (Middle Ordovician Series) serve as the material foundation for karstification. These dolomites were deposited in an oxidized shallow-water tidal flat setting, which endowed them with favorable lithological properties for subsequent dissolution. (2) NE-SW trending erosional grooves within the paleogeomorphology of the Ordovician top surface functioned as preferential flow paths for karst water, channeling fluid movement and intensifying localized dissolution. (3) Multi-phase tectonic activities, particularly extensional deformation during the Himalayan orogeny, created the necessary stress conditions to trigger cave collapse. (4) KCCs undergo a multi-stage formation and evolution process: Starting with the Majiagou Formation’s 5th Member dolomites as the primary lithology, initial modification occurred via Caledonian weathering–crust karstification. Subsequently, compressional tectonism during the Yanshanian orogeny generated void spaces that facilitated deep-seated dissolution. Rapid uplift in the Paleogene exacerbated vertical dissolution, leading to extensive cavity development, which ultimately collapsed under the extensional tectonic regime of the Neogene. This study provides theoretical support for predicting and mitigating sudden water inrushes caused by KCCs in the Hancheng Mining Area. Furthermore, it offers novel insights and a scientific basis for advancing understanding of the developmental mechanisms of North China-type KCCs. Full article
Show Figures

Figure 1

11 pages, 340 KB  
Article
EZ Lyn: A Confirmed Period-Bouncer Cataclysmic Variable Below the Period Minimum
by Nadezhda L. Vaidman, Almansur T. Agishev, Serik A. Khokhlov and Aldiyar T. Agishev
Galaxies 2025, 13(6), 121; https://doi.org/10.3390/galaxies13060121 - 30 Oct 2025
Viewed by 109
Abstract
We model the short-period cataclysmic variable EZ Lyn with MESA binary evolution and infer its present-day parameters through a staged statistical search. First, we compute a coarse grid of tracks in (M1,0,P0) at fixed [...] Read more.
We model the short-period cataclysmic variable EZ Lyn with MESA binary evolution and infer its present-day parameters through a staged statistical search. First, we compute a coarse grid of tracks in (M1,0,P0) at fixed M2,0 and rank snapshots by a profile likelihood. We then resample the neighbourhood of the minimum to build a refined Δχ2 surface. Finally, we sample this surface with an affine-invariant MCMC to obtain posteriors, using a likelihood that treats the one-sided constraint on the donor temperature and the ambiguity of component roles in the binary output. The best-fit snapshot reproduces the observables and identifies EZ Lyn as a period bouncer with a substellar donor. We infer MWD=0.850±0.019M, M2=0.0483±0.0137M, RWD=0.0092±0.0001R, R2=0.099±0.005R, TWD=11,500±20K, and T2=1600±50K. The instantaneous mass-transfer rate at the best-fit snapshot is M˙=3.66×1011Myr1, consistent with the secular range implied by the white-dwarf temperature. Independent checks from the Roche mean-density relation, surface gravities, and the semi-empirical donor sequence support the solution. In population context, EZ Lyn lies in the period-minimum spike and on the low-mass tail of the donor mass–period plane. The classification is robust to modest displacements along the shallow Δχ2 valley. We release inlists, tracks, and analysis scripts for reproducibility. Full article
Show Figures

Figure 1

26 pages, 15176 KB  
Article
Combined Geophysical–Geodynamic Analysis of the Plio-Pleistocene Hominin Dispersal Through the Levantine Corridor
by Lev V. Eppelbaum and Youri I. Katz
Appl. Sci. 2025, 15(21), 11554; https://doi.org/10.3390/app152111554 - 29 Oct 2025
Viewed by 100
Abstract
The origin of humans on Earth is closely linked to understanding how ancient populations dispersed into adjacent territories. Traditionally, studies have identified landscape and climatic changes as the primary factors in this dispersal. However, we propose that regional tectonic and geodynamic factors also [...] Read more.
The origin of humans on Earth is closely linked to understanding how ancient populations dispersed into adjacent territories. Traditionally, studies have identified landscape and climatic changes as the primary factors in this dispersal. However, we propose that regional tectonic and geodynamic factors also played a significant role in shaping these movements. To analyze this phenomenon, we employed several primary methods, including radiometric dating, magnetostratigraphy, paleomagnetic correlation, isotope–oxygen analysis, tectonothermal studies, gravity mapping, paleobiogeographic assessment, lithofacies analysis, and event and cyclic stratigraphy. Our research indicates that the Akchagylian hydrospheric maximum, which reached up to +200 m, significantly limited the early dispersal of hominins from Africa to Eurasia. The migration corridor was shaped by tectonic activity between the Dead Sea Transform and the boundary of the Mesozoic Terrane Belt carbonate platform. We argue that, during the early stages of hominin evolution in East Africa, the Levantine Corridor (LC) had not yet developed into an optimal route for dispersal, either tectonically or paleogeographically. Suitable habitats for early hominins emerged only after the regression at the end of the Middle Gelasian, around two million years ago, when sea level fell by approximately 200 m, leading to the dissection of the coastal high plateau of the Eastern Mediterranean. We therefore suggest that the LC became established only after the termination of the Akchagylian transgression and the subsequent landscape reconfiguration of the Eastern Mediterranean. Our integrated analysis, combining paleomagnetic, structural, tectonic, and event stratigraphy data, indicates that the age of the renowned ‘Ubeidiya site in northern Israel is several thousand years older than previously thought. This paleogeographic impact had not been considered in earlier studies. Considering the diverse and complex factors that governed hominin dispersal from Africa into Eurasia within this multifaceted region, we propose that the scope of research should be broadened. Our detailed study of the Carmel area, located northeast of the Levantine Corridor and influenced by it during the Pleistocene, indicates that this region was inundated during the early phases of hominin migration out of Eastern Africa. Besides this, we have conducted an integrated geological–geophysical landscape analysis of the central part of the Israeli coastal plain. Full article
Show Figures

Figure 1

17 pages, 5800 KB  
Article
Cortical Tubers’ Transformation in Pediatric Patients Diagnosed with Tuberous Sclerosis Complex: A Retrospective Longitudinal MRI Analysis
by Camilla Russo, Simone Coluccino, Maria Fulvia De Leva, Stefania Graziano, Carmela Russo, Federica Mazio, Maria De Liso, Domenico Cicala, Anna Nastro, Federica Palladino, Serena Troisi, Pietro Spennato, Giuseppe Cinalli, Antonio Varone and Eugenio Maria Covelli
J. Clin. Med. 2025, 14(21), 7665; https://doi.org/10.3390/jcm14217665 - 29 Oct 2025
Viewed by 167
Abstract
Background: Cortical tubers (CTs) are hallmark brain lesions in tuberous sclerosis complex (TSC), historically considered stable in number over time; prior literature has correlated overall CT burden on magnetic resonance imaging (MRI) with disease severity. As longitudinal imaging studies assessing CTs’ evolution [...] Read more.
Background: Cortical tubers (CTs) are hallmark brain lesions in tuberous sclerosis complex (TSC), historically considered stable in number over time; prior literature has correlated overall CT burden on magnetic resonance imaging (MRI) with disease severity. As longitudinal imaging studies assessing CTs’ evolution over time are lacking, we aim to investigate temporal changes in CTs—both in number and signal—on MRI in a cohort of pediatric TSC patients. Methods: A retrospective single-center analysis was conducted on 57 pediatric TSC patients who underwent longitudinal MRI studies in a 10-year span. Required MRI sequences included volumetric unenhanced T1-weighted, SWI, T2w and/or FLAIR. CTs were evaluated by two neuroradiologists and classified into five subtypes (A, B, C1, C2, D) according to signal characteristics. Statistical comparison was performed using t-tests. Results: Paired t-test analysis demonstrated a significant longitudinal increase in the overall number of CTs, rising from 16.11 ± 12.43 at baseline to 18.77 ± 13.29 at follow-up (mean difference = −2.67, 95% CI [−3.94, −1.39]; t (56) = 4.19; p < 0.0001), corresponding to a moderate effect size (Cohen’s d ≈ 0.56). When stratified by age, patients <2 years—representing the incompletely myelinated subgroup—showed a more pronounced increase in CT burden, from 19.46 ± 15.21 to 24.17 ± 15.75 (mean difference = −4.71, 95% CI [−7.37, −2.04]; t (23) = 3.65; p = 0.0013; d ≈ 0.75). In contrast, patients aged ≥2 years demonstrated a smaller but still significant increase, from 13.67 ± 9.45 to 14.85 ± 9.64 (mean difference = −1.18, 95% CI [−2.08, −0.28]; t (32) = 2.68; p = 0.0115; d ≈ 0.46). Direct comparison between the two subgroups using Welch’s two-sample t-test confirmed that the mean CT count in patients <2 years was significantly higher than in those ≥2 years (mean difference = 3.53 ± 1.36; t = 2.59; df = 28.4; p = 0.0075), with a large effect size (Cohen’s d ≈ 0.78). Type C1-C2 tubers evolved from pre-existing earlier-stage lesions, while most newly visible CTs over time were type A-B. Type D tubers remained rare and derived from earlier-stage CTs. Conclusions: Contrary to previous assumptions, CTs in pediatric TSC showed a tendency to increase in number and evolve in signal over time, thus challenging the notion of stability and suggesting dynamic behavior. Incomplete myelination in early infancy may impact MRI CTs detection by reducing contrast with surrounding brain tissue, potentially leading to their underestimation/misidentification. Full article
(This article belongs to the Section Clinical Pediatrics)
Show Figures

Figure 1

47 pages, 4097 KB  
Article
Tracing Images, Shaping Narratives: Eight Decades of Rock Art Research in Chile, South America (1944–2024)
by Daniela Valenzuela, Indira Montt, Marcela Sepúlveda and Persis B. Clarkson
Arts 2025, 14(6), 130; https://doi.org/10.3390/arts14060130 - 28 Oct 2025
Viewed by 152
Abstract
80 years of Chilean rock art research, from its early descriptive stages in the 1940s to the present-day integration of relational ontologies, archaeometric techniques, and interdisciplinary perspectives, is reviewed. 562 publications are analysed, covering four major regions: the Arid North, Semi-Arid North, South-Central, [...] Read more.
80 years of Chilean rock art research, from its early descriptive stages in the 1940s to the present-day integration of relational ontologies, archaeometric techniques, and interdisciplinary perspectives, is reviewed. 562 publications are analysed, covering four major regions: the Arid North, Semi-Arid North, South-Central, and Southernmost Chile. Drawing from a systematically constructed corpus, we trace the evolution of research questions, theoretical orientations, and methodologies over time, with attention to regional trends and institutional dynamics. Results reveal a gradual shift from typological classification toward more complex approaches addressing mobility, landscape, coloniality, visual agency, and human/non-human relationships. The Arid North emerges as the primary centre of innovation, while southern regions remain in exploratory stages despite recent advances. Comparison with global research trajectories shows how Chile’s situated approaches—marked by decentralisation, theoretical pluralism, and critical reflection—contribute to decolonial and southern perspectives in rock art studies. Rather than reproducing hegemonic models, Chilean scholarship offers alternative epistemologies rooted in context-specific materiality and historical processes. The review highlights the potential of Chilean rock art research to expand the theoretical and methodological horizons of the discipline, positioning it as a fertile field for dialogue with contemporary archaeology and global visual studies. Full article
(This article belongs to the Special Issue Advances in Rock Art Studies)
Show Figures

Figure 1

13 pages, 1905 KB  
Article
Study on Partial Discharge Characteristics of Mixed Metal Particles Under Combined Power Frequency and Switching Impulse Voltage
by Jiyun Ren, Yongfu Ma, Quanlei Qu, Zile Wang, Yuang Wang, Lili Wang, Xutao Han and Xiaojie Yang
Energies 2025, 18(21), 5650; https://doi.org/10.3390/en18215650 - 28 Oct 2025
Viewed by 176
Abstract
Under operating conditions, metallic particle contaminants inside Gas-Insulated Switchgears (GIS) represent a major threat that can initiate partial discharges (PD) and lead to insulation failure. To investigate the discharge patterns under combined AC and switching impulse voltages, this paper presents an experimental study [...] Read more.
Under operating conditions, metallic particle contaminants inside Gas-Insulated Switchgears (GIS) represent a major threat that can initiate partial discharges (PD) and lead to insulation failure. To investigate the discharge patterns under combined AC and switching impulse voltages, this paper presents an experimental study conducted in SF6 gas on wire-shaped, spherical, and Mixed Metal Particles. By synchronously analyzing PD time-domain waveforms, Phase-Resolved Partial Discharge (PRPD) patterns, and high-speed motion camera recordings, the correlation between particle motion behavior and discharge signals was systematically examined. The results indicate that wire particles exhibit a significant discharge initiation delay under the combined voltage; however, intense, discrete discharges with large magnitudes occur during their vertical jumping phase. In contrast, spherical particles can be activated within the first power frequency cycle without delay, but the subsequent discharge magnitudes are limited. The characteristics of hybrid particles lie between these two types, demonstrating a staged evolution described as “spherical particles lead initiation, wire particles dominate discharge.” Furthermore, under the sustained AC voltage, hybrid particles trigger a more dispersed and violent discharge process. These findings reveal the complex motion-discharge mechanism of Mixed Metal Particles, providing critical insights for fault mechanism analysis and insulation protection related to particle contamination in practical GIS equipment. Full article
Show Figures

Figure 1

Back to TopTop