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36 Results Found

  • Review
  • Open Access
1,381 Views
16 Pages

14 August 2025

Giant somatosensory evoked potentials (gSEPs) are abnormally high-amplitude cortical responses to peripheral nerve stimulation, traditionally regarded as electrophysiological hallmarks of progressive myoclonic epilepsies (PMEs). However, accumulating...

  • Case Report
  • Open Access
2,276 Views
8 Pages

Unilateral Transient Enhanced SEP during Integrated Multiparameter Neurophysiological Monitoring in a Newborn with Symptomatic Seizure

  • Sara Cavaliere,
  • Silvia Lori,
  • Maria Bastianelli,
  • Cesarina Cossu,
  • Simonetta Gabbanini,
  • Carlo Dani and
  • Giovanna Bertini

During Integrated Multiparametric Neurophysiological Monitoring (IMNA), a newborn with suspected hypoxia at birth and microhaemorrhagic and ischaemic lesions presented some clonic-tonic episodes with specific EEG patterns characterized by rolandic an...

  • Article
  • Open Access
5 Citations
3,008 Views
14 Pages

Proximal Upper Limb Sensorimotor Integration in Response to Novel Motor Skill Acquisition

  • Sinead O’Brien,
  • Danielle Andrew,
  • Mahboobeh Zabihhosseinian,
  • Paul Yielder and
  • Bernadette Murphy

22 August 2020

Previous studies have shown significant changes in cortical and subcortical evoked potential activity levels in response to motor training with the distal upper-limb muscles. However, no studies to date have assessed the neurological processing chang...

  • Article
  • Open Access
6 Citations
4,280 Views
16 Pages

24 September 2018

Recent work found that experimental pain appeared to negate alterations in cortical somatosensory evoked potentials (SEPs) that occurred in response to motor learning acquisition of a novel tracing task. The goal of this experiment was to further inv...

  • Article
  • Open Access
1 Citations
20,966 Views
31 Pages

Neuroplastic Responses to Chiropractic Care: Broad Impacts on Pain, Mood, Sleep, and Quality of Life

  • Heidi Haavik,
  • Imran Khan Niazi,
  • Imran Amjad,
  • Nitika Kumari,
  • Usman Ghani,
  • Moeez Ashfaque,
  • Usman Rashid,
  • Muhammad Samran Navid,
  • Ernest Nlandu Kamavuako and
  • Amit N. Pujari
  • + 1 author

7 November 2024

Objectives: This study aimed to elucidate the mechanisms of chiropractic care using resting electroencephalography (EEG), somatosensory evoked potentials (SEPs), clinical health assessments (Fitbit), and Patient-reported Outcomes Measurement Informat...

  • Article
  • Open Access
3 Citations
3,717 Views
19 Pages

Source Localization of Somatosensory Neural Generators in Adults with Attention-Deficit/Hyperactivity Disorder

  • Heather S. McCracken,
  • Bernadette A. Murphy,
  • Ushani Ambalavanar,
  • Cheryl M. Glazebrook and
  • Paul C. Yielder

20 February 2023

Attention-Deficit/Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder, where differences are often present relating to the performance of motor skills. Our previous work elucidated unique event-related potential patterns of neural activity...

  • Article
  • Open Access
3 Citations
4,755 Views
11 Pages

Acute Effects of Aerobic Exercise on Somatosensory-Evoked Potentials in Patients with Mild Cognitive Impairment

  • Imran Amjad,
  • Imran Khan Niazi,
  • Hamza Ghazanfar Toor,
  • Rasmus Bach Nedergaard,
  • Muhammad Shafique,
  • Kelly Holt,
  • Heidi Haavik and
  • Touqeer Ahmed

23 September 2020

Mild cognitive impairment (MCI) is becoming a serious problem for developing countries as the lifespan of populations increases. Exercise is known to be clinically beneficial for MCI patients. Somatosensory-evoked potentials (SEPs) may be a potential...

  • Article
  • Open Access
1 Citations
1,927 Views
12 Pages

Comparison of Subdural and Intracortical Recordings of Somatosensory Evoked Responses

  • Felipe Rettore Andreis,
  • Suzan Meijs,
  • Thomas Gomes Nørgaard dos Santos Nielsen,
  • Taha Al Muhamadee Janjua and
  • Winnie Jensen

25 October 2024

Micro-electrocorticography (µECoG) electrodes have emerged to balance the trade-off between invasiveness and signal quality in brain recordings. However, its large-scale applicability is still hindered by a lack of comparative studies assessing...

  • Article
  • Open Access
1 Citations
2,235 Views
13 Pages

21 December 2023

To explore whether temporal electroencephalography (EEG) traits can dissociate the physical properties of touching objects and the congruence effects of cross-modal stimuli, we applied a machine learning approach to two major temporal domain EEG trai...

  • Article
  • Open Access
18 Citations
3,475 Views
12 Pages

Cortical Reorganization of Early Somatosensory Processing in Hemiparetic Stroke

  • Jordan N. Williamson,
  • William A. Sikora,
  • Shirley A. James,
  • Nishaal J. Parmar,
  • Louis V. Lepak,
  • Carolyn F. Cheema,
  • Hazem H. Refai,
  • Dee H. Wu,
  • Evgeny V. Sidorov and
  • Julius P. A. Dewald
  • + 1 author

31 October 2022

The cortical motor system can be reorganized following a stroke, with increased recruitment of the contralesional hemisphere. However, it is unknown whether a similar hemispheric shift occurs in the somatosensory system to adapt to this motor change,...

  • Article
  • Open Access
1,158 Views
10 Pages

Background: We aimed to determine the utility of different electrodiagnostic (EDx) methods in diagnosing meralgia paresthetica (MP). Methods: Twenty-nine MP patients and 26 controls were included. Sensory nerve action potential (SNAP) and somatosenso...

  • Brief Report
  • Open Access
2 Citations
2,401 Views
7 Pages

Sex Differences in Excitatory and Inhibitory Function in the Primary Somatosensory Cortex during the Early Follicular Phase: A Preliminary Study

  • Sayaka Anazawa,
  • Koya Yamashiro,
  • Taiki Makibuchi,
  • Koyuki Ikarashi,
  • Tomomi Fujimoto,
  • Genta Ochi and
  • Daisuke Sato

Background and objectives: We examined sex differences in the excitatory and inhibitory functions of the primary somatosensory cortex (S1) between males and females during the early follicular phase, when estradiol hormones are unaffected. Methods: F...

  • Article
  • Open Access
10 Citations
7,135 Views
15 Pages

29 April 2023

The current investigation used somatosensory evoked potentials (SEPs) to assess differences in sensorimotor integration and somatosensory processing variables between asymptomatic individuals with and without forward head posture (FHP). We assessed d...

  • Article
  • Open Access
1,238 Views
13 Pages

Evaluation of the Relationship between Pain Exposure and Somatosensory Evoked Potentials in Preterm Infants: A Prospective Cohort Study

  • Caterina Coviello,
  • Silvia Lori,
  • Giovanna Bertini,
  • Simona Montano,
  • Simonetta Gabbanini,
  • Maria Bastianelli,
  • Cesarina Cossu,
  • Sara Cavaliere,
  • Clara Lunardi and
  • Carlo Dani

Background and aim: First, to compare somatosensory evoked potentials (SEPs) in preterm newborns without major brain injury studied at term equivalent age (TEA) with a term historical control group. Second, to investigate the impact of pain exposure...

  • Article
  • Open Access
4 Citations
2,074 Views
11 Pages

Is There a Role for Intraoperative Neuromonitoring in Intradural Extramedullary Spine Tumors? Results and Indications from an Institutional Series

  • Manuela D’Ercole,
  • Quintino Giorgio D’Alessandris,
  • Michele Di Domenico,
  • Benedetta Burattini,
  • Grazia Menna,
  • Alessandro Izzo,
  • Filippo Maria Polli,
  • Giuseppe Maria Della Pepa,
  • Alessandro Olivi and
  • Nicola Montano

6 July 2023

While intraoperative neurophysiological monitoring (IONM) is considered a standard for intramedullary spinal cord tumor surgery, the effective role of IONM in intradural extramedullary (IDEM) tumors is still debated. We present the results of 60 pati...

  • Article
  • Open Access
15 Citations
5,393 Views
18 Pages

8 June 2019

Objective: The aim of this study was to investigate the effects of different preprocessing parameters on the amplitude of median nerve somatosensory evoked potentials (SEPs). Methods: Different combinations of two classes of filters (Finite Impulse R...

  • Feature Paper
  • Article
  • Open Access
7 Citations
3,437 Views
25 Pages

Effect of Neck Muscle Fatigue on Hand Muscle Motor Performance and Early Somatosensory Evoked Potentials

  • Mahboobeh Zabihhosseinian,
  • Paul Yielder,
  • Rufeyda Wise,
  • Michael Holmes and
  • Bernadette Murphy

9 November 2021

Even on pain free days, recurrent neck pain alters sensorimotor integration (SMI) measured via somatosensory evoked potentials (SEPs). Neck muscle fatigue decreases upper limb proprioception, and thus may interfere with upper limb motor task acquisit...

  • Article
  • Open Access
2 Citations
1,783 Views
9 Pages

14 September 2023

Cortical responses in somatosensory evoked potentials (SEP) are enhanced in patients with amyotrophic lateral sclerosis (ALS). This study investigated whether sensory gating is involved in the pathophysiology of sensory cortical hyperactivity in ALS...

  • Article
  • Open Access
3 Citations
4,095 Views
14 Pages

During training in a novel dynamic environment, the non-dominant upper limb favors feedback control, whereas the dominant limb favors feedforward mechanisms. Early somatosensory evoked potentials (SEPs) offer a means to explore differences in cortica...

  • Article
  • Open Access
1 Citations
7,964 Views
10 Pages

Assessing the Effects of the Topical Application of L-Menthol on Pain-Related Somatosensory-Evoked Potentials Using Intra-Epidermal Stimulation

  • Taiki Makibuchi,
  • Koya Yamashiro,
  • Sayaka Anazawa,
  • Tomomi Fujimoto,
  • Genta Ochi,
  • Koyuki Ikarashi and
  • Daisuke Sato

L-menthol is known to activate transient receptor potential melastatin 8 (TRPM8) and induce analgesia to thermal stimuli. However, since thermal stimulation leads to the interaction among the other TRP channels, it was unclear whether L-menthol cause...

  • Article
  • Open Access
1 Citations
4,711 Views
14 Pages

Restoration of Genuine Sensation and Proprioception of Individual Fingers Following Transradial Amputation with Targeted Sensory Reinnervation as a Mechanoneural Interface

  • Alexander Gardetto,
  • Gernot R. Müller-Putz,
  • Kyle R. Eberlin,
  • Franco Bassetto,
  • Diane J. Atkins,
  • Mara Turri,
  • Gerfried Peternell,
  • Ortrun Neuper and
  • Jennifer Ernst

10 January 2025

Background/Objectives: Tactile gnosis derives from the interplay between the hand’s tactile input and the memory systems of the brain. It is the prerequisite for complex hand functions. Impaired sensation leads to profound disability. Various i...

  • Review
  • Open Access
1 Citations
808 Views
12 Pages

18 June 2025

Neurophysiological techniques, particularly somatosensory evoked potentials (SEPs) and electroencephalography (EEG), are essential tools for the functional and prognostic evaluation of patients with prolonged disorders of consciousness (DoC) in inten...

  • Article
  • Open Access
16 Citations
9,497 Views
19 Pages

Investigating the Effects of Chiropractic Spinal Manipulation on EEG in Stroke Patients

  • Muhammad Samran Navid,
  • Imran Khan Niazi,
  • Dina Lelic,
  • Rasmus Bach Nedergaard,
  • Kelly Holt,
  • Imran Amjad,
  • Asbjørn Mohr Drewes and
  • Heidi Haavik

Objective: The purpose of this study was to evaluate the impact of chiropractic spinal manipulation on the early somatosensory evoked potentials (SEPs) and resting-state electroencephalography (EEG) recorded from chronic stroke patients. Methods: Sev...

  • Article
  • Open Access
3 Citations
2,875 Views
18 Pages

4 October 2023

Experimentally induced neck fatigue and neck pain have been shown to impact cortico-cerebellar processing and sensorimotor integration, assessed using a motor learning paradigm. Vibration specifically impacts muscle spindle feedback, yet it is unknow...

  • Article
  • Open Access
2 Citations
3,153 Views
11 Pages

Habituation of Somatosensory Evoked Potentials in Patients with Alzheimer’s Disease and Those with Vascular Dementia

  • Antonio Currà,
  • Lucio Marinelli,
  • Filippo Cotellessa,
  • Laura Mori,
  • Chiara Avanti,
  • Daniela Greco,
  • Manuela Gorini,
  • Paolo Missori,
  • Francesco Fattapposta and
  • Carlo Trompetto

14 December 2021

Background and Objectives: The most prevalent dementia are Alzheimer’s disease and vascular dementia. There is evidence that cortical synaptic function may differ in these two conditions. Habituation of cortical responses to repeated stimuli is...

  • Article
  • Open Access
3 Citations
2,750 Views
25 Pages

EEG Investigation on the Tactile Perceptual Performance of a Pneumatic Wearable Display of Softness

  • Federico Carpi,
  • Michele C. Valles,
  • Gabriele Frediani,
  • Tanita Toci and
  • Antonello Grippo

21 November 2023

Multisensory human–machine interfaces for virtual- or augmented-reality systems are lacking wearable actuated devices that can provide users with tactile feedback on the softness of virtual objects. They are needed for a variety of uses, such a...

  • Article
  • Open Access
3 Citations
3,029 Views
11 Pages

Myasthenia Gravis—An Analysis of Multimodal Evoked Potentials

  • Edyta Dziadkowiak,
  • Marta Waliszewska-Prosół,
  • Małgorzata Wieczorek,
  • Joanna Bladowska,
  • Sławomir Budrewicz and
  • Maria Ejma

11 August 2021

Introduction: The aim of this study is a comprehensive analysis of the parameters of exogenous evoked potentials (visual, brainstem auditory, and somatosensory) in patients with myasthenia gravis (MG), a prototype of both neuromuscular junction disea...

  • Review
  • Open Access
11 Citations
2,946 Views
16 Pages

13 June 2023

Familial adult myoclonus Epilepsy (FAME) is a non-coding repeat expansion disorder that has been reported under different acronyms and initially linked to four main loci: FAME1 (8q23.3–q24.1), FAME 2 (2p11.1–q12.1), FAME3 (5p15.31–p...

  • Article
  • Open Access
11 Citations
4,121 Views
22 Pages

Parametrizing the Conditionally Gaussian Prior Model for Source Localization with Reference to the P20/N20 Component of Median Nerve SEP/SEF

  • Atena Rezaei,
  • Marios Antonakakis,
  • MariaCarla Piastra,
  • Carsten H. Wolters and
  • Sampsa Pursiainen

3 December 2020

In this article, we focused on developing the conditionally Gaussian hierarchical Bayesian model (CG-HBM), which forms a superclass of several inversion methods for source localization of brain activity using somatosensory evoked potential (SEP) and...

  • Article
  • Open Access
350 Views
16 Pages

Association Between Electrophysiological Evaluation and Muscle Quality Changes in the Lower Limb of Subacute Stroke Patients: A Pilot Longitudinal Observational Study

  • Se Jin Kim,
  • Jeong Hwan Lee,
  • Young Sook Park,
  • Hyun Jung Chang,
  • Jin Gee Park,
  • Eun Sol Cho,
  • Jae Yeon Kim and
  • Dong Jin Ha

11 November 2025

Background: This pilot longitudinal observational study investigated 4-week changes in lower limb muscle quantity and quality in patients with subacute stroke and explored risk factors associated with these changes. Methods: Twenty-six patients with...

  • Article
  • Open Access
3 Citations
2,052 Views
21 Pages

NeuroAiDTM-II (MLC901) Promoted Neurogenesis by Activating the PI3K/AKT/GSK-3β Signaling Pathway in Rat Spinal Cord Injury Models

  • Anam Anjum,
  • Muhammad Dain Yazid,
  • Muhammad Fauzi Daud,
  • Jalilah Idris,
  • Angela Min Hwei Ng,
  • Amaramalar Selvi Naicker,
  • Ohnmar Htwe Rashidah Ismail,
  • Ramesh Kumar Athi Kumar and
  • Yogeswaran Lokanathan

Traumatic damage to the spinal cord (SCI) frequently leads to irreversible neurological deficits, which may be related to apoptotic neurodegeneration in nerve tissue. The MLC901 treatment possesses neuroprotective and neuroregenerative activity. This...

  • Article
  • Open Access
30 Citations
7,168 Views
13 Pages

Value of Micro-CT for Monitoring Spinal Microvascular Changes after Chronic Spinal Cord Compression

  • Hou-Qing Long,
  • Wen-Han Xie,
  • Wen-Li Chen,
  • Wen-Lin Xie,
  • Jing-Hui Xu and
  • Yong Hu

7 July 2014

Neurological degeneration can occur after compression of the spinal cord. It is widely accepted that spinal cord compression leads to ischemic lesions and ultimately neurological dysfunction due to a narrowed spinal canal. Therefore, an in-depth unde...

  • Article
  • Open Access
10 Citations
4,777 Views
17 Pages

Prior work showed differential alterations in early somatosensory evoked potentials (SEPs) and improved motor learning while in acute tonic pain. The aim of the current study was to determine the interactive effect of acute tonic pain and early motor...

  • Article
  • Open Access
2 Citations
2,087 Views
13 Pages

21 April 2025

The strong correlation between evoked potentials (EPs) and American Spinal Injury Association (ASIA) scores in individuals with spinal cord injury (SCI) suggests that EPs may serve as reliable predictive markers for rehabilitation progress. Numerous...

  • Article
  • Open Access
5 Citations
3,144 Views
21 Pages

8 February 2023

The progression and remission of cervical spondylotic myelopathy (CSM) are quite unpredictable due to the ambiguous pathomechanisms. Spontaneous functional recovery (SFR) has been commonly implicated in the natural course of incomplete acute spinal c...

  • Review
  • Open Access
3 Citations
2,649 Views
19 Pages

23 August 2024

Background: Neurological injury poses a significant challenge in aortic surgery, encompassing spinal cord injury from thoraco-abdominal aorta intervention or stroke post-surgery on the arch and ascending aorta. Despite ample literature and proposals,...