Search Results (80)

Polymer flooding is an enhanced oil recovery (EOR) technique that improves oil extraction by injecting polymer solutions into reservoirs. However, the disposal and treatment of polymer flooding waste liquids (PFWL) present significant challenges due to their high viscosity, complex molecular structure, and environmental impact. This study investigates the shear-induced degradation of polymer solutions, focusing on rheological properties, particle size distribution, and morphological changes under controlled shear conditions. Experimental results show that shear forces significantly reduce the viscosity of polymer solutions, with shear rates of 4285.36 s⁻¹ in the rotating domain and 3505.21 s⁻¹ in the fixed domain. The particle size analysis reveals a significant reduction in average particle size, indicating polymer aggregate breakup. SEM images confirm these morphological changes. Additionally, numerical simulations using a power-law model highlight the correlation between shear rate, wall shear stress, and polymer degradation efficiency. This study suggests that optimizing rotor–stator configurations with high shear forces is essential for efficient polymer degradation, offering insights for designing more effective polymer waste liquid treatment systems in oilfields. Full article

Scramjet operation requires a comprehensive understanding of the internal flowfield, encompassing fuel–air mixing and combustion. This study investigates transient flow and flame development within a HIFiRE-2 scramjet engine combustor, which features two opposing cavities and dual sets of fuel injectors—the upstream (primary) and downstream (secondary) injectors. These cavities function as flameholders, creating circulating flows with elevated temperatures and pressures. Shock waves form both ahead of fuel plumes and at the diverging and converging sections of the flowpath. Special attention is given to the interactions among these shock waves and the shear layers along the supersonic core flow as the system progresses towards a quasi-steady state. Driven by increased backpressure, bow shocks and disturbances induced by the normal, secondary fuel injection and the inclined, primary fuel injection move upstream, amplifying the cavity pressure. These shocks generate adverse pressure gradients, causing near-wall flow separation adjacent to both injector sets, which enhances the penetration and dispersion of fuel plumes. Once a quasi-steady state is achieved, a feedback loop is established between dynamic wave motions and combustion processes, resulting in sustained entrainment of reactive mixtures into the cavities. This mechanism facilitates stable combustion in the cavities and near-wall separation zones. Full article

During the long-term operation of salt cavern gas storage, multiple injections and extractions of gas will cause periodic temperature changes in the storage, resulting in thermal fatigue damage to the surrounding rock of the salt cavern and seriously affecting the stability of the storage. This article takes the salt rock samples after thermal fatigue treatment as the research object, adopts a uniaxial compression test, and combines DIC and Acoustic Emission (AE) technology to study the influence of different temperatures and cycle times on the mechanical properties of salt rock. The results indicate that as the number of cycles and upper limit temperature increase, thermal stress induces continuous propagation of microcracks, leading to continuous accumulation of structural damage, enhanced radial deformation, and intensified local displacement concentration, causing salt rock to enter the failure stage earlier. The initial stress for expansion and the volume expansion at the time of failure both show a decreasing trend. After 40 cycles, the compressive strength and elastic modulus decreased by 23.8% and 27.4%, respectively, and the crack failure mode gradually shifted from tension-dominated to tension-shear composite. At the same time, salt rock exhibits typical “elastic-plastic creep” behavior under uniaxial compression, but the uneven expansion and thermal fatigue effects caused by periodic temperature changes suppress plastic slip, resulting in an overall decrease in peak strain energy. The proportion of elastic strain energy increases from 21% to 38%, and the deformation process shows a trend of enhanced elastic dominant characteristics. The changes in the physical and mechanical properties of salt rock under periodic temperature effects revealed by this study can provide an important theoretical basis for the long-term safe operation of underground salt cavern storage facilities. Full article

The efficient extraction of natural gas from marine natural gas hydrate (NGH) reservoirs is challenging, due to their low permeability, high hydrate saturation, and fine-grained sediments. Hydraulic fracturing has been proven to be a promising technique for improving the permeability of these unconventional reservoirs. This study presents a comprehensive triaxial experimental investigation of the fracturing behavior and fracture initiation mechanisms of NGH-bearing sediments, using large-scale ice-saturated synthetic cubic models. The experiments systematically explore the effects of key parameters, including the injection rate, fluid viscosity, ice saturation, perforation patterns, and in situ stress, on fracture propagation and morphology. The results demonstrate that at low fluid viscosities and saturation levels, transverse and torsional fractures dominate, while longitudinal fractures are more prominent at higher viscosities. Increased injection rates enhance fracture propagation, generating more complex fracture patterns, including transverse, torsional, and secondary fractures. A detailed analysis reveals that the perforation design significantly influences the fracture direction, with 90° helical perforations inducing vertical fractures and fixed-plane perforations resulting in transverse fractures. Additionally, a plastic fracture model more accurately predicts fracture initiation pressures compared to traditional elastic models, highlighting a shift from shear to tensile failure modes as hydrate saturation increases. This research provides new insights into the fracture mechanisms of NGH-bearing sediments and offers valuable guidance for optimizing hydraulic fracturing strategies to enhance resource extraction in hydrate reservoirs. Full article

Polymer co-extrusion experiments are described simulating the dynamics of two different magmas (e.g., silicic and mafic having different viscosities) flowing simultaneously in a vertical volcanic pipe or conduit which results in the effusion of composite lava domes on the surface. These experiments, involving geologically realistic conduit length-to-diameter aspect ratios of 130:1 or 380:1, demonstrate that co-extrusion of magmas having different viscosities can explain not only the observed normal zoning observed in planar dikes and the pipelike conduits that evolve from dikes but also the compositional layering of effused lava domes. The new results support earlier predictions, based on observations of induced core-annular flow (CAF), that dike and conduit zoning along with dome layering are found to depend on the viscosity contrast of the non-Newtonian (shear-thinning) magmas. Any magma properties creating viscosity differences, such as crystal content, bubble content, water content and temperature may also give rise to the CAF regime. Additionally, codependent flow behavior involving the silicic and mafic magmas may play a significant role in modifying the nature of volcanic eruptions. For example, lubrication of the flow by an annulus of a more mafic, lower-viscosity component allows a more viscous but more volatile-charged magma to be injected rapidly to greater vertical distances along a dike into a lower pressure regime that initiates exsolving of a gas phase, further assisting ascent to the surface. The rapid ascent of magmas exsolving volatiles in a dike or conduit is associated with explosive silicic eruptions. Full article

Vaccines usually contain an adjuvant that activates innate immunity to promote the acquisition of adaptive immunity. Aluminum and lipid nanoparticles have been used for this purpose, but their accumulation or widespread circulation in the body can lead to adverse effects. In contrast, physical adjuvants, which use physical energy to transiently stress tissues, do not persist in exposed tissues or cause lasting adverse effects. Herein, we investigate the effects of intradermal injection of endotoxin-free ovalbumin (OVA) protein alone without additional adjuvants using a needle-free pyro-drive jet injector (PJI) on tumor vaccination efficacy. Intradermal injection of OVA protein alone using PJI significantly increased OVA-specific CD8⁺ T cell expansion in the lymph node, although lymph node swelling was much less than when aluminum hydroxide was used. The injection also induced OVA-specific killing activity and antibody production and showed strong CD8⁺ T cell-dependent prophylactic antitumor effects against transplanted E.G7-OVA tumors. In particular, intradermal injection of the fluorescent OVA protein significantly enhanced its uptake by XCR1⁺ dendritic cells, which have a strong ability to cross-present extracellular proteins in the skin and draining lymph nodes. In addition, the injection increased the expression of HMGB1, one of the potent danger signals whose expression has been reported to increase in response to shear stress. Thus, intradermal injection of OVA protein alone without any additional adjuvants using PJI induces potent CD8⁺ T cell-mediated antitumor immunity by enhancing its uptake into XCR1⁺ dendritic cells, which have a high cross-presentation capacity accompanied by an increased expression of shear stress-induced HMGB1. Full article

Reducing the water content in soft soil is crucial for improving its load-bearing capacity. However, traditional vacuum preloading demonstrates limited effectiveness for dredged sludge due to its high water content and low permeability, resulting in inadequate consolidation and long treatment durations. To address these limitations, this study proposes a new improvement approach that combines pressurized air injection with a polyacrylamide (PAM) addition to enhance vacuum consolidation. Experimental results demonstrated that cationic polyacrylamide (CPAM) exhibited superior performance in improving water discharge efficiency, which promoted the aggregation of fine soil particles and reduced the clogging of drainage channels through adsorption bridging. The incorporation of pressurized air injection further enhanced consolidation efficiency by increasing hydraulic gradients and inducing micro-fractures in soil, thereby improving soil permeability and vacuum pressure transmission. However, excessive CPAM addition or high-pressure air injection was found to compromise the effectiveness of the vacuum preloading treatment due to drainage channel clogging and extensive soil fracturing. The appropriate consolidation performance was achieved with a 0.075% CPAM addition and 20 kPa air pressure injection, demonstrating a 24.5% increase in water discharge mass and a 30.9% improvement in soil shear strength compared to traditional methods. Microstructural analysis revealed a more compacted soil matrix with reduced porosity and enhanced interparticle interactions. These findings provide valuable insights for improving the treatment efficiency of dredged sludge in coastal regions, particularly in the Nansha District of Guangzhou. Full article

Casing deformation (CD) is generally believed to be caused by the slip of fractures in the strata and its shear effects on horizontal wells. However, the casing deformation mode based on this theory cannot fully match the measurement data, and the differential deformation characteristics and the mechanism behind this phenomenon are not completely clear. To elucidate the mechanisms of CD and enhance prevention and control measures, the CD modes in Shunan Block were identified and deformation mechanisms of these modes were comprehensively investigated. Our research shows the following: (1) Under the mechanism of penetrating fracture shear deformation, CD exhibit obvious shear deformation, and the natural fractures near the intersection point with the wellbore are prone to form a higher risk of deformation. (2) Natural fractures with tips approaching the wellbore experience intense stress concentration (1.6 times higher than shear stress) during activation, resulting in compression and asymmetrical CD. (3) The shear deformation induced by penetrating fractures is 15.52 mm, while the fracture tip-induced compression deformation demonstrates a substantially greater magnitude at 44.17 mm. This compressive deformation exceeds the shear deformation by a factor of approximately 2.85. (4) The stress concentration at the fracture tip is highly sensitive to the injection rate. Hence, adherence to the “avoiding stress concentration” principle is crucial in hydraulic fracturing operations. The conclusion indicates that in addition to penetrating fracture shear deformation, fracture tip compression deformation is another significant mechanism that causes CD. This research finding can offer theoretical guidance for developing effective measures to prevent and control CD in the exploitation of deep shale gas. Full article

The fluorenyl methyl oxycarbonyl phenylalanyl-phenylalanine methyl ester (Fmoc-Phe-Phe-Ome) was synthetized using the liquid phase synthesis strategy. This derivative was separated by hydrophobic interaction chromatography, its purity was analyzed by RP-HPLC and it was characterized by mass spectrometry. This extremely hydrophobic peptide conjugate was incorporated into aqueous solutions of Pluronic^® F127 at low temperatures (below 10 °C). The temperature induced sol–gel transition was investigated by rheological measurements. A delay of the sol–gel transition, caused by the presence of low concentrations of Fmoc-Phe-Phe-Ome (up to 1%), enables better control of the gelation process. The viscoelastic properties of hybrid networks were investigated at 37 °C in different shear conditions. The Pluronic/peptide systems reported herein provide promising alternatives for developing innovative injectable gels as suitable platforms in cancer treatment. Full article

Different gas hydrate types, such as methane hydrate and carbon dioxide hydrate, exhibit distinct geomechanical responses and hydrate morphologies in gas-hydrate-bearing sediments (GHBSs). However, most constitutive models for GHBSs focus on methane-hydrate-bearing sediments (MHBSs), while largely overlooking carbon-dioxide-hydrate-bearing sediments (CHBSs). This paper proposes a modified Mohr–Coulomb (M-C) model for GHBSs that incorporates the geomechanical effects of both MHBSs and CHBSs. The model integrates diverse hydrate morphologies—cementing, load-bearing, and pore-filling—into hydrate saturation and incorporates an effective confining pressure. Its validity was demonstrated through simulations of reported triaxial compression tests for both MHBSs and CHBSs. Moreover, a variance-based sensitivity analysis using Sobol’s method evaluated the effects of hydrate-related soil properties on the geomechanical behavior of GHBSs. The results indicate that the shear modulus influences the yield axial strain of the CHBSs and could be up to 1.15 times more than that of the MHBSs. Similarly, the bulk modulus showed an approximate 5% increase in its impact on the yield volumetric strain of the CHBSs compared with the MHBSs. These findings provide a unified framework for modeling GHBSs and have implications for CO₂-injection-induced methane production from deep sediments, advancing the understanding and simulation of GHBS geomechanical behavior. Full article

The development of powder-fueled ramjets is challenged by the mechanisms of flow mixing for the combustion of powder fuel in supersonic airflows. This paper describes a series of numerical simulations on the injection process of boron powder fuel in a cavity-based supersonic combustion chamber with induced shock. Under different solid-to-gas ratios ranging from 20 to 0.1, this study explored the evolution of supersonic flow fields with strong shear and discontinuities. It also discusses the flow processes and mixing characteristics of powder fuel within them. The study found that the enhancement of powder fuel mixing is mainly related to the rotational regions of large-scale vortex structures. Vortex structures with the required intensity and area can be obtained by adjusting the appropriate solid-to-gas ratio. Moreover, reasonable induction methods can enhance the interaction between particles and vortex structures, thereby achieving mixing enhancement. The interaction between powder fuels and the peripheral rotating regions of these vortices significantly improves the mixing efficiency, with the highest average mixing efficiency increased by 30%. This research lays a foundation for developing mixing enhancement strategies and supports the advancement of efficient and stable powder-fueled ramjets. Full article

Underground reservoir technology in coal mines enables the effective storage and utilization of water resources disturbed by mining activities. Owing to the effects of mining operations and water extraction/injection activities, the water head in underground reservoirs fluctuates dynamically. The total bearing capacity of a coal pillar dam is significantly reduced due to the combined effects of overlying rock stress, dynamic and static water pressures, and mining-induced stresses, which are critical for ensuring the safe operation of underground reservoirs. Based on the correlation between different water head heights and the corresponding water pressures on the coal pillar dam, a custom-made coal rock pressure water immersion test device was used to saturate the coal samples under various water pressure conditions. The mechanical deformation and failure characteristics of the samples and fracture propagation patterns under different water pressure conditions were studied using uniaxial compression, acoustic emission (AE), and three-dimensional X-ray microimaging. The results indicated that, compared with the dry state, the peak strain of the water-immersed coal samples increased to varying degrees with increasing water pressure. Additionally, the average porosity and the number of pores with diameters in the range of 0 to 150 μm significantly increased in water-immersed coal samples. Under the combined influence of water immersion pressure and uniaxial stress, loading the water-saturated coal samples to the fracture damage threshold significantly intensified deformation, failure, and fracture propagation within the samples, and the failure mode changed from tension to a composite tensile–shear failure. Full article

Fibre deformation (or shearing of yarns) can develop during the liquid moulding of composites due to injection pressures or polymerisation (cross-linking) reactions (e.g., chemical shrinkage). On that premise, this may also induce potential residual stress–strain, warpage, and design defects in the composite part. In this paper, a developed numerical framework is customised to analyse deformations and the residual stress–strain of fibre (at a micro-scale) and yarns (at a meso-scale) during a liquid composite moulding (LCM) process cycle (fill and cure stages). This is achieved by linking flow simulations (coupled filling–curing simulation) to a transient structural model using ANSYS software. This work develops advanced User-Defined Functions (UDFs) and User-Defined Scalers (UDSs) to enhance the commercial CFD code with extra models for chemorheology, cure kinetics, heat generation, and permeability. Such models will be hooked within the conservation equations in the thermo-chemo-flow model and hence reflected by the structural model. In doing so, the knowledge of permeability, polymerisation, rheology, and mechanical response can be digitally obtained for more coherent and optimised manufacturing processes of advanced composites. Full article

Wound infections caused by Staphylococcus aureus often result in localized suppurative lesions that severely impede the healing process, so it is urgent to develop a dress with efficient antimicrobial and pro-healing functions. In this study, the bifunctional injectable hydrogel lactoferrin (Lf)/NZ2114/lithium magnesium silicate hydrogel (LMSH) was first successfully prepared through the electrostatic interaction method. The physical, biological, and efficacy properties are systematically analyzed with good shear-thinning capacity and biocompatibility. More importantly, it inhibits infection and promotes wound healing in a mouse wound infection model after 14 d treatment, and the bactericidal rate and healing rate were over 99.92% and nearly 100%, respectively. Meanwhile, the massive reduction of inflammatory cells, restoration of tissue structure, and angiogenesis in mice showed the anti-inflammatory and pro-healing properties of the hydrogel. The healed wounds showed thickening with more hair follicles and glands, suggesting that the hydrogel Lf/NZ2114/LMSH (Three in One) could be a better dressing candidate for the treatment of S. aureus-induced wound infections. Full article

The alternating stress caused by periodic high-pressure injection and extraction in gas storage can potentially induce fault slippage, compromising the sealing integrity of faults within these storages sites. Understanding the mechanical behavior of faults under alternating stress is crucial for ensuring the long-term stability and safety of gas storage operations. To explore the impact of fault dip angle and fault gouge strength on fault slip characteristics, fault samples were prepared with uniaxial compressive strengths of 20.1, 30.2, 42.4, and 51.4 MPa at two distinct dip angles. Triaxial compression experiments were conducted under alternating stress conditions corresponding to operational pressures at a specific gas storage site in China. The results indicate that faults with dip angles of 30° and 45° tend to fail at their weakest points. The increasing strength of fault gouges shifts failure mechanisms from interfacial failure between gouges and the surrounding rock towards internal gouge failure, often accompanied by shear failure across sections, resulting in characteristic “X”-shaped conjugate shear failures. The decrease in the ratio of bedrock strength to fault gouge strength elucidates the observed phenomena of an initial reduction followed by increased fault deformation. Transition points for faults with 30° and 45° dips occur around the strength ratios of 1.7/1 and 1.2/1, respectively. Fault damage exhibits a negative correlation with fault gouge strength and a positive correlation with fault dip angle. Samples with a higher-strength fault gouge at a 30° dip angle generally incur less damage compared to those with a lower-strength fault gouge at a 45° dip angle. Moreover, higher maximum static friction coefficients denote greater fault resistance to slipping, with 30° faults consistently demonstrating superior resistance compared to 45° faults. Additionally, a higher-strength fault gouge consistently enhances slip resistance under identical dip angles. Full article