Search Results (14,139)

Background/Objectives: Recently, the importance of physical activity for health promotion has increased the demand for physical activities performed in natural environments. However, environmental characteristics that enhance the efficiency of physical activities and contribute to health promotion have not yet been established. This study aimed to verify the mental and physical health of walking in different environments by measuring EEG and HR responses among middle-aged women living in urban areas during forest trail (GU) and school ground (NF) walking. Methods: In total, 30 middle-aged women participated in a 1.5 km walking, with HR measured during normal, NF, and GU walking. EEGs were recorded before and after walking 5 waves (Delta, Theta, Alpha, Beta, and Gamma). All data were collected under standardized conditions and analyzed using paired t-tests. Results: Alpha, beta, and gamma waves increased after GU walking (p < 0.001) but decreased after NF walking, suggesting that walking in natural environments promotes emotional stability, attentional recovery, and cognitive activation. Mean HR during GU was higher than during NF (p < 0.001), and NF walking corresponded to moderate-intensity exercise, whereas GU walking represented vigorous-intensity activity, likely influenced by its 5% slope and multi-sensory natural stimuli such as forest, sounds, and air quality. Conclusions: This study is not a clinical trial but a health experiment of physical activity, highlighting how walking in natural environments can contribute to improved health. The walking environment elicits distinct mental and physical responses, and forest walking has proven to be more effective in improving health. This result highlights the value of nature-based exercise spaces accessible in urban environments and can help with design and health policies. Full article

Background/Objectives: Reports detailing rehabilitative interventions for infants with severe dermatologic disorders are scarce. Epidermolysis Bullosa (EB) is a genetic disorder characterized by skin fragility, which causes blistering after minor trauma. Since there is still no cure in general clinics, symptomatic treatment and developmental support are essential for managing the condition. While physiotherapy and occupational therapy guidelines for EB exist, descriptions of neonatal habilitation/rehabilitation are insufficient. Case: This case report describes the longitudinal habilitation/rehabilitation intervention process for a newborn with Dowling–Meara EB, the most severe form, from admission to the Neonatal Intensive Care Unit (NICU) until discharge. Since maneuvers requiring contact were strictly limited due to skin vulnerability, rehabilitation interventions were implemented utilizing the opportunity afforded by necessary care. Intervention strategies were modified according to developmental stages and skin stability, with a particular emphasis on sensory development, postural control training, and fostering the mother–child relationship. This report is the first to describe the applicability of sensory rehabilitation and the use of behavioral cues to facilitate voluntary movements. In addition, careful respiratory rehabilitation was implemented for comorbid tracheomalacia with specific attention to skin vulnerability. The child achieved stable head/neck control, symmetrical limb movements, reaching, guided rolling, and stable oxygenation by the time of discharge. Conclusions: Balancing skin disorder prevention and motor–neural development requires flexible approaches that minimize contact while utilizing routine care as a training opportunity. Our experience will contribute to the progress in the habilitation, wound rehabilitation and respiratory rehabilitation of infants with severe dermatologic disorders. Full article

Ticks use multiple sensory organs to facilitate host detection, including Haller’s organs (HOs) that allow ticks to sense infrared (IR) radiation from potential hosts. Additionally, ticks have primitive eyes to sense light sources. The possibility exists that these senses may detect stimuli that attract ticks to road edge habitat, where IR radiation tends to be elevated. We investigated the role of the HOs and eyes in the attraction of adult American dog ticks, Dermacentor variabilis, towards road edge habitat(s). Adult D. variabilis were collected from multiple study sites and separated into three groups: (1) Haller’s organs removed; (2) eyes painted with black nail polish; and (3) unmodified ticks (control). All tick groups were marked with a unique fluorescent paint color and released 7.5 m from the road edge at two study sites. Tick movements were tracked at night using ultraviolet lights, tick position(s) were recorded using flags, and measurements were recorded to track tick movement in relation to the release point and road edge. Surface temperatures were recorded at the road edge and in the field to detect a potential thermal stimulus. Mixed-effects models were applied to investigate the significance of tick proximity to the road edge between the groups and sites. Our results demonstrated that the control unmodified group was significantly closer to the road edge than the modified groups lacking Haller’s organ or eyes (p ≤ 0.0001, p = 0.0049), leading to the conclusion that unmodified ticks move towards road edges. Modifying ticks, either by removing the HO or eyes of adult D. variabilis decreased tick movement toward road edges. Full article

To improve the drying efficiency and quality of Scutellaria baicalensis (S. baicalensis) for both medicinal and beverage purposes, this study examined the effects of temperature, vacuum degree, and rotation speed during rotary microwave vacuum drying. The study focused on drying kinetics, physicochemical properties, and sensory quality of the Scutellaria slices. Multivariate analyses, including hierarchical cluster and correlation network analyses, were used to explore the relationship between parameters and quality. Results showed that the method significantly reduced drying time and improved moisture migration. It also preserved active components like baicalin, wogonoside, total phenolics, and polysaccharides, with high antioxidant activity maintained. Temperature was the key factor. The best balance was achieved with 50 °C, −75 kPa, and 4.2 rad/s, resulting in high drying efficiency, a sensory acceptability score of 8.8, turbidity of 12.4 NTU, and strong antioxidant capacity. Cluster analysis distinguished microwave-vacuum-dried samples from those dried by traditional methods (natural air-drying and hot-air drying). Correlation network analysis revealed positive links between sensory acceptance, active components, and liquor clarity. This optimized parameter set is recommended for producing high-quality Scutellaria ingredients for consumers. Full article

Background: Asymmetrical load carrying can impair balance and increase fall risk, especially in older adults. This study compared postural control in 33 older (mean age 72.2 ± 11.0 years) and 27 younger (mean age 33.5 ± 15.8 years) adults. Methods: Participants performed three 20 s quiet standing trials on a force plate: no load, 3 kg left shoulder load, and 3 kg right shoulder load. Center-of-pressure (COP) variability, range, mean velocity, and sample entropy were computed. This was a quasi-experimental study with a mixed-design ANOVA (Group as between-subjects factor; Load and Plane as within-subjects factors). Results: Younger adults showed better overall stability than older adults across conditions. Older adults had larger COP range than younger adults with no load and with the right-sided load. Notably, no significant difference in COP range was found between groups with the left-sided load. Key statistical findings included the significant Load × Group interaction (F(2, 116) = 3.9, p = 0.024, η_p² = 0.06) for COP range. Conclusions: A small asymmetrical load on the left side may be associated with postural control in older adults, possibly through familiar sensory cues. Conversely, a right-sided load appears to negatively impact their balance. These findings highlight the differential effects of load side on postural control in older individuals. Full article

Citywalk, a recently emerging form of leisure-oriented mobility, reflects increasing public interest in healthier lifestyles and more immersive urban experiences in Chinese metropolises. This study develops an integrative assessment framework combining Importance–Performance Analysis (IPA) and the Kano model to examine both functional and affective dimensions of pedestrian satisfaction. Based on a multidimensional assessment model that integrates 25 factors of pedestrian perception, large-scale surveys were conducted in Beijing, Shanghai, and Guangzhou, focusing on perceptions of spatial form, sensory atmosphere, accessibility, safety, and supporting facilities. A Satisfaction Scale (SS) and an Importance Scale (IS) were used to quantify responses, and the Kaiser–Meyer–Olkin (KMO) statistic indicated adequate sampling reliability. Results show that in Beijing and Shanghai, Biodiversity Visibility and Ecological Connection (LE5 = 3.706) and Street Furniture and Urban Amenity Integration (IN2 = 3.255) respectively rank first in terms of satisfaction, while Guangzhou showed highest satisfaction ratings with Pedestrian Infrastructure and Circulation Systems (IN3 = 3.206). It concludes that accessibility, safety, and route signage represent basic expectations whose absence substantially lowers satisfaction, and integration of cultural narratives were identified as effective design features associated with improved comfort and engagement. The framework and findings provide an empirical basis for analyzing pedestrian experience and identifying priorities for improving citywalk environments under different urban conditions. Full article

Nanotechnology offers powerful new tools to enhance food quality monitoring and safety assurance. In the food industry, nanoscale materials (e.g., metal, metal oxide, carbon, and polymeric nanomaterials) are being integrated into sensory systems to detect spoilage, contamination, and intentional food tampering with unprecedented sensitivity. Nanosensors can rapidly identify foodborne pathogens, toxins, and chemical changes that signal spoilage, overcoming the limitations of conventional assays that are often slow, costly, or require expert operation. These advances translate into improved food safety and extended shelf-life by allowing early intervention (for example, via antimicrobial nano-coatings) to prevent spoilage. This review provides a comprehensive overview of the types of nanomaterials used in food sensory applications and their mechanisms of action. We examine current applications in detecting food spoilage indicators and adulterants, as well as recent innovations in smart packaging and continuous freshness monitoring. The advantages of nanomaterials—including heightened analytical sensitivity, specificity, and the ability to combine sensing with active preservative functions—are highlighted alongside important toxicological and regulatory considerations. Overall, nanomaterials are driving the development of smarter food packaging and sensor systems that promise safer foods, reduced waste, and empowered consumers. However, realizing this potential will require addressing safety concerns and establishing clear regulations to ensure responsible deployment of nano-enabled food sensing technologies. Representative figures of merit include Au/AgNP melamine tests with LOD 0.04–0.07 mg L⁻¹ and minute-scale readout, a smartphone Au@carbon-QD assay with LOD 3.6 nM, Fe₃O₄/DPV detection of Sudan I at 0.001 µM (linear 0.01–20 µM), and a reusable Au–Fe₃O₄ piezo-electrochemical immunosensor for aflatoxin B1 with LOD 0.07 ng mL⁻¹ (≈15 × reuse), alongside freshness labels that track TVB-N/amine in near-real time and e-nose arrays distinguishing spoilage stages. Full article

Climate change poses a major challenge for wine production in semi-arid regions, where grape ripening frequently leads to excessive sugar accumulation and reduced acidity. This study evaluated the combined effect of cold pre-fermentative maceration (PM) and the use of non-Saccharomyces yeasts (Lachancea thermotolerans and Torulaspora delbrueckii) on the composition and sensory properties of Cayetana Blanca wines. Pre-fermentative maceration increased titratable acidity by 0.5 g/L and yeast-assimilable nitrogen by 28 mg/L, creating more favorable conditions for the metabolic activity of non-Saccharomyces species. Wines fermented with L. thermotolerans—especially in sequential inoculation with S. cerevisiae after PM—showed the highest acidity and lactic acid content (2 g/L), together with 1% v/v lower ethanol and 1 g/L higher glycerol than the control. These wines were perceived as fresher and better balanced, despite a moderate decrease in fruity esters such as ethyl hexanoate, ethyl octanoate, and isoamyl acetate. Cluster analysis confirmed that non-Saccharomyces fermentations developed distinct compositional profiles only when combined with PM. Overall, the PM + L. thermotolerans + S. cerevisiae treatment achieved the most favorable balance between acidity, ethanol, and sensory freshness. This approach provides a sustainable and readily applicable method to enhance acidity and freshness in white wines from warm-climate regions. Full article

Insects rely heavily on olfaction to regulate essential behaviors such as host location, oviposition and mating. The invasive cotton mealybug, Phenacoccus solenopsis Tinsley represents a global threat to cotton and numerous cultivated crops. To elucidate the molecular basis of its olfaction mechanisms, we sequenced and assembled antennal transcriptomes from male and female adults using Illumina NovaSeq X Plus technology. Among 13,891 unigenes, 91 chemosensory genes were identified, including 40 odorant receptors, 13 gustatory receptors, 19 ionotropic receptors, 10 odorant-binding proteins, 7 chemosensory proteins, and 2 sensory neuron membrane proteins. Differential expression analysis revealed 6312 genes with significant sex-biased expression between male and female antennae, including 55 chemosensory genes. Phylogenetic analyses further clarified the evolutionary relationships of these chemosensory genes with homologs from other hemipteran species. Notably, validation confirmed that 18 PsolORs were male-biased. This comprehensive transcriptomic study establishes a foundation for further functional characterization of pheromone reception and provides valuable candidate genes for dissecting chemoreception mechanisms in P. solenopsis. Full article

Background: The aim of the study was to analyze the clinical characteristics and circumstances of relapses in the patients with relapsing-remitting multiple sclerosis (MS). Objectives: The eighty patients with clinically definite MS and relapsing-remitting course were enrolled in the retrospective study. Methods: The calendar of documented recurrences was analyzed, looking for any patterns across years, warm and cold periods, and seasons and months. Results: In the years 2015–2020 the majority of relapses occurred in March, June–July, and October; with regard to seasons, the relapse rate peaked during spring and summer. In 2021–2023 there was significant increase in relapses in May and in February. In these years, most cases occurred in spring, and the least in autumn. The most significant coincidences were found for sensory symptoms in January, optic neuritis in March, motor deficit with pyramidal signs in May and June, cerebellar symptoms in March and July, and spinal cord involvement signs in August. Conclusions: Observation of seasonal occurrence of relapses revealed periods with high temperature, low humidity, and variable atmospheric pressure as potential contributors. Better recognition of these issues within future investigations could be considered in the complex approach to the management of MS outcomes. Full article

Ready-to-cook (RTC) meat products provide convenience but are more susceptible to quality degradation during refrigerated storage. This study examined the effects of 1%, 2%, and 3% chitosan coating on the quality parameters and shelf life of pretreated seekh kabab samples compared with non-coated seekh kabab (NC-SK) samples stored at 4 °C for 28 days. The results show that the chitosan-coated seekh kabab (CC-SK) samples had higher lightness and stable redness values during storage compared with the NC-SK samples. The moisture loss was significantly higher (p < 0.05) in the NC-SK samples on days 21 and 28. The chitosan coating effectively retarded lipid oxidation, protein oxidation, and total viable basic nitrogen formation and preserved the natural pH during storage from days 14 to 28 compared with the NC-SK samples (p < 0.05). After 21 days, the total viable count, Enterobacteriaceae, LAB, and S. aureus counts were higher (p < 0.05) in the NC-SK samples than in the CC-SK samples. The sensory scores of the NC-SK samples fell below the acceptable limit compared with those of the CC-SK samples on day 28. A combined effect of refrigeration temperature and chitosan coating enables long storage time, prevents microbial growth, and minimizes lipid oxidation. Full article

This study investigated the potential of rapeseed protein isolate (RPI) as a sustainable alternative to soy protein isolate (SPI) in chicken pâtés, considering the combined effects of protein (SPI or RPI) and oil (sunflower or rapeseed) sources. The proximate composition, pH, water activity (a_w), and colour of the RPI-based formulations were largely comparable to their SPI counterparts and remained stable over 60 days of refrigerated storage. However, at day 0, the RPI-based samples exhibited lower pH values (approx. 6.09 vs. 6.41), slightly lower lightness (L* approx. 68.9 vs. 72.5), higher redness (a* approx. 4.72 vs. 3.58), and higher yellowness (b* approx. 23.3 vs. 9.38), indicating some initial formulation-dependent differences. Furthermore, RPI-based formulations exhibited enhanced textural properties and improved oxidative stability, likely due to synergistic effects between rapeseed protein and oil. The substitution of sunflower oil with rapeseed oil significantly improved the fatty acid profile (p < 0.05), notably increasing α-linolenic acid (C18:3n-3) and achieving a favourable n-6/n-3 ratio (approx. 2.8). Sensory evaluation revealed that the formulation combining both rapeseed ingredients provided a stable and highly acceptable profile. These results collectively demonstrate that RPI is a viable and functional replacer for SPI, enabling the production of nutritious, high-quality, and sustainable chicken pâtés. Full article

Tomato is one of the most important vegetable crops worldwide, with about one quarter of the yearly production of fresh fruits dispatched to the processing industry. Paste, canned tomatoes, and sauces represent the three leading categories. Background/Objectives: The metabolic profile of processed tomatoes can be modified by several production steps, affecting the nutritional and sensory profile of the finished product. Despite this, a detailed metabolomic profiling of transformed tomatoes is currently missing. The goal of this investigation is to provide qualitative metabolomic profiling of tomato purees with two main advances: first, the use of a more sustainable analytical approach based on a single extraction protocol and one-shot analysis for multiple information retrieval on different compound classes; second, the achievement of a curated database consolidated over a wide collection of commercial samples representative of the Italian market. Methods: A non-selective ethanol extraction was applied to collect the main polar metabolites followed by untargeted high-resolution MS/MS analysis and software-based compound identification. Results: A list of more than five hundred features was collected and assigned to specific compounds or compound groups with different confidence levels. The results confirmed the persistence in processed tomatoes of the main primary and secondary metabolites already reported in fresh fruits, such as essential amino acids, sugar, organic acids, vitamins, fatty acyls, and phytohormones. Moreover, new insight on specific components never traced before in similar finished samples is provided. Bioactive compounds were detected in all samples, such as oligopeptides with ACE-inhibitor activity, ɣ-aminobutyric acid, alkaloids, and polyphenols (flavonoids, coumarins, and cinnamic acids). Many of these compounds have antioxidant activities, proving the relevance of transformed tomatoes as a source of health-promoting compounds for the human diet. Conclusions: A detailed metabolic profile of commercial tomato puree samples was obtained, and a curated database of metabolites was compiled, which can be useful for multiple purposes, for example, authentication, quality, or nutritional assessments. Full article

The incorporation of bioactive compounds into food products represents a promising approach to enhance their functional and health-promoting properties. However, many bioactive compounds, such as polyphenols, essential oils, carotenoids, and omega-3 fatty acids, are highly sensitive to environmental factors, including temperature, oxygen, and light, which limits their direct application in the food industry. Microencapsulation has emerged as an innovative strategy to overcome these challenges by protecting bioactive compounds, improving their stability, controlling their release, and masking undesirable flavors or odors. This article reviews recent advances in microencapsulation techniques, including spray-drying, freeze-drying, coacervation, and innovative methods such as nanoencapsulation and electrospinning. Particular attention is given to the influence of encapsulated bioactive compounds on the physicochemical characteristics, texture, color, and sensory attributes of various food matrices. Furthermore, the paper highlights industrial perspectives, emphasizing the scalability of these techniques, regulatory considerations, and their role in the development of clean-label, functional, and sustainable food products. The findings underline the potential of microencapsulation as a key technology for the next generation of functional foods, bridging consumer expectations with industrial feasibility. Full article