Search Results (25,448)

This work investigates the fabrication and performance of axially compressed isotropic epoxy-bonded NdFeB-type magnets produced from melt-spun powders with partial substitution of (Nd,Pr) by (La,Ce). Four alloy compositions were synthesized and processed into bonded magnets using two powder-to-binder weight ratios (95:5 and 96.5:3.5). Structural analysis confirms that all substituted alloys retain the tetragonal Nd₂Fe₁₄B phase (up to ~95 wt%) even at high substitution levels, while the lattice parameters decrease slightly with increasing (La,Ce) content. Microscopy analysis confirms a homogeneous distribution of the binder phase around the powder particles, demonstrating uniform binder–powder integration. Thermal analysis reveals composition-dependent Curie temperatures and enhanced crystallization onset in highly substituted powders. Magnetic measurements on both powders and bonded magnets show that increasing substitution leads to a gradual reduction in remanence, coercivity, and energy product, though all samples maintain strong hard-magnetic behavior. Increasing the powder fraction to 96.5 wt.% significantly improves all magnetic parameters due to higher magnetic-phase density and enhanced interparticle coupling, yielding bonded magnets with densities up to ~80% of the theoretical value. The resulting magnets achieve competitive performance, uniform field distribution and isotropic magnetization with (BH)max values about 65 kJ/m³, a coercivity around 660 kA/m, and superior thermal stability compared with commercial bonded NdFeB magnets. Overall, partial substitution with light rare-earth elements (La,Ce) provides a cost-effective route to high-density bonded NdFeB magnets that combine strong magnetic performance, enhanced thermal stability, and suitability for lightweight, complex-shaped industrial applications. Surprisingly, the coefficients of the temperature variation of coercivity and (BH)_max are much better compared to the commercial NdFeB bonded magnets. Full article

The accelerating transition to low carbon energy systems has intensified the demand for nickel and cobalt from low-grade (<1.5 wt.%) refractory lateritic ores. These low-grade laterites are however not amenable to conventional beneficiation due to their complex mineralogy, eclectic physicochemical properties, and fine Ni–Co dissemination. This review examines recent advances made in the extraction of nickel and cobalt from complex low-grade lateritic ores, emphasizing the interplay between ore mineralogy, chemistry, beneficiation, pretreatment, and processing route selection. Developments in selective ore comminution–classification have led to the generation of Ni-rich fine fractions (undersize) and Co-rich coarse fractions (oversize), enabling differentiated extraction strategies that improve resource utilization, frugal energy use, and process efficiency. Mechanical activation via stirred media milling, thermal calcination-induced structural disorder, and dehydroxylate goethite products, are shown to significantly enhance Ni–Co leaching kinetics under both atmospheric and heap leaching conditions. A critical comparison of pyrometallurgical (rotary-kiln electric furnace) and hydrometallurgical (HPAL, EPAL, heap, atmospheric, bioleaching) routes demonstrates that ore-specific optimization is essential to balance recovery, acid consumption, and greenhouse gas emissions. The novel resin in moist mix (RIMM) process, which integrates ambient leaching and in situ ion exchange selective recovery, is shown to offer potential for sustainable values extraction from sub-economic resources. Furthermore, the review highlights the key innovation challenges and concomitant opportunities for enhanced critical battery metal recovery from complex laterite ores. Full article

High-performance geared turbofan engines generate significant heat within the planetary power gearbox. This study presents the thermal design of an integrated fan guide vane heat exchanger aimed at recovering gearbox heat losses with minimal pressure loss and converting them into useful propulsive energy via the Junkers–Meredith Effect. Hot gearbox oil is routed through hollow fan static guide vanes, enabling heat transfer to the bypass airflow while simultaneously reducing oil temperature and augmenting thrust. A comprehensive analytical framework is applied, incorporating heat transfer modeling, guide vane geometry reconstruction, lubrication flow sizing, and propulsion performance evaluation for both take-off and cruise flight conditions, using the PW1127G-JM geared turbofan as the reference engine. The results indicate that the proposed system can achieve a thrust increase of up to 6.4% at the end of take-off and deliver a thrust-specific fuel consumption reduction of up to 5.6% during take-off and approximately 2% during cruise. While sufficient heat dissipation is achieved under cruise conditions, take-off operation requires a higher transient oil temperature. Overall, this study demonstrates that integrating heat recovery into existing engine structures offers a promising pathway to enhance propulsion efficiency, reduce fuel consumption, and support more sustainable aircraft engine designs. Full article

Road transport decarbonization remains a strategic priority in the context of the global climate emergency. Between 2013 and 2024, most economic sectors in the European Union reduced emissions, whereas the transport and storage sector increased them by 14%, largely driven by road freight demand. This review provides an updated overview of the decarbonization status of the road transport fleet across all segments, with particular focus on heavy-duty freight, which remains 97.9% fossil-fuel dependent. It examines short- and medium-term decarbonization pathways for the existing fleet, highlighting liquid biofuels as an immediately deployable option where full electrification is constrained by technological and economic barriers. Among these options, fatty acid methyl ester (FAME) and hydrotreated vegetable oil (HVO) stand out due to their compatibility with current engines and fuel distribution infrastructure, but each presents specific limitations. Biodiesel raises concerns over long-term engine durability, while HVO requires further evidence on its impact on NO_x emissions and fuel lubricity. When these sustainable fuels are used with or without fossil diesel, there are still several unanswered questions. The emerging use of HVO/FAME blends is therefore discussed as a promising route to mitigate the drawbacks of each fuel, and a research agenda is proposed to support accelerated decarbonization of heavy-duty road freight in the EU. Full article

Microplastics (MPs) have emerged as a growing environmental and food safety concern, with their presence widely reported in aquatic organisms and seafood. However, their occurrence in traditionally processed and fermented fish products remains unexplored. This study provides the first evidence of MP contamination in ethnic fermented fish products of Northeast India, namely Ngari, Hentak, and Shidal. MPs were analyzed for abundance, size distribution, morphology, color, and polymer composition using microscopic examination and Laser Raman Spectroscopy. The average MP abundance was 16.50 ± 5.18 MPs/g in Ngari, 15.73 ± 4.83 MPs/g in Shidal, and 20.50 ± 3.00 MPs/g in Hentak. Fibers and fragments were the dominant morphotypes across all products, with transparent and black particles occurring most frequently. Polymer characterization revealed polyethylene (PE) and polypropylene (PP) as the predominant polymers, followed by polyamide (PA), polyvinyl chloride (PVC), and polystyrene (PS). Size distribution analysis showed that MPs in the 101–300 µm range were most abundant in Ngari and Shidal, whereas smaller MPs (<50 µm) predominated in Hentak. The use of whole fish, including the gastrointestinal tract and gills, primary sites for MP accumulation, along with non-standardized fermentation practices and atmospheric deposition during retail, likely contributes to contamination. These findings highlight an overlooked route of human exposure to MPs through traditional fermented foods and underscore the need for improved processing practices and mitigation strategies to safeguard food safety and sustainability. Full article

In this work, the effects of Nb and Mo additions on the precipitation behavior and strengthening mechanisms of three ultra-low carbon Ti-Mo-Nb steels with a predominantly ferritic microstructure were investigated under two different thermo-mechanical processing (TMP) routes. A water-quenching step after hot rolling followed by furnace cooling was found to refine the average precipitate size and increase their volume fraction, leading to a significant strength improvement. Specifically, this process increased the yield strength by approximately 110~180 MPa, reaching levels above 750 MPa, with the 22Mo-Nb steel achieving a peak ultimate tensile strength of ~790 MPa. The precipitates exhibited dispersed, interphase, and grain boundary morphologies, none of which correlated directly with the TMP route or steel composition. While variations in Mo content showed little influence on precipitate characteristics, the addition of Nb markedly promoted precipitation. The strength of these Ti-Mo-Nb ferritic steels is primarily determined by precipitation strengthening. Through optimized TMP parameters and microalloying additions, the overall precipitation strengthening contribution was elevated to the 300~400 MPa range. Full article

Green-synthesis routes for producing CuO nanoparticles offer a simplified, sustainable, and low-cost replacement for conventional chemical methods, eliminating the need for harsh chemicals and providing an easily scalable process for industrial-level production. Although numerous studies have investigated synthesizing CuO nanoparticles from single plant extracts, comparative assessments of multi-plant-mediated CuO nanoparticles alongside synthetic CuO remain limited. In this work, CuO nanoparticles were green-synthesized from three different plant sources, namely ginger, red onion peels, and garlic, and their physicochemical and biological properties were tested against the synthetic CuO. All plant extracts produced pure-phased monoclinic CuO nanoparticles as confirmed by UV–Vis, XRD, FTIR, and SEM/EDX analyses. SEM showed distinct nanoparticle morphologies, with CuO from ginger extract exhibiting uniform nanocubes, while nanoparticles from red onion and garlic extracts exhibited more aggregated and irregular structures. Their crystallite sizes were 8–9 nm lower than the ~11 nm observed for the synthetic CuO, highlighting the phytochemical role in shaping the nanoparticles’ morphology. The antibacterial efficacy against S. aureus and E. coli showed that ginger-derived and synthetic CuO had the strongest bacterial inhibition and bactericidal potency compared to onion- and garlic-derived CuO samples. However, synthetic CuO had the highest cytotoxicity risk, hindering its suitability for biological uses, while CuO-ginger maintained good cell viability at moderate concentrations. CuO-onion and CuO-garlic gave lower antibacterial cytocompatibility performance due to their thicker capping layers, which led to decreased Cu²⁺ release and ROS production. Ginger-derived CuO achieved an optimal trade-off between antibacterial and cytotoxic efficiency, highlighting its prospects as a candidate for biomedical applications. Full article

CO₂ cycloaddition with epoxides offers a sustainable route for CO₂ utilization, yet the simultaneous activation of both substrates remains challenging. Herein, using UiO-66(Zr)-NH₂ (denoted as UZN) as a model system, we illustrate that dual-active sites consisting of unsaturated Zr⁴⁺ centers and amine groups can efficiently accelerate CO₂ fixation with epoxides under visible light. The unique ensemble in UZN optimizes light harvesting, promotes charge carrier separation, and enriches bifunctional active sites for efficient adsorption and activation of epoxides and CO₂. Consequently, UZN exhibits significantly improved CO₂-epoxide cycloaddition performance compared to UiO-66(Zr)-H (denoted as UZH), achieving a PC yield of 99.5%, with a production rate of 9.97 mmol·g⁻¹·h⁻¹. This work establishes a clear coordination–photocatalytic synergy in MOF-based systems and provides fundamental insights and a generalizable strategy for designing advanced catalysts for CO₂ transformation. Full article

Background/Objectives: Migraine is a leading cause of disability in women and is intricately linked to hormonal fluctuations and systemic health. This review aims to unravel the complex relationship between migraine, cardiovascular disease, and metabolic syndrome throughout the female reproductive lifespan. Methods: A comprehensive narrative review was conducted using the PubMed database for studies published between January 1988 and December 2025. Keywords included “migraine”, “cardiovascular risk”, “metabolic syndrome”, “pregnancy”, and “hormonal therapy”. Articles were selected to synthesize the latest pathophysiological evidence and clinical guidelines. Results: Migraine prevalence in women is two to threefold higher than in men, peaking during fertile age. Hormonal milestones, particularly estrogen withdrawal, trigger menstrual migraine. Metabolic syndrome is significantly more common in migraineurs than the general population. Obesity and insulin resistance have been associated with higher migraine attack frequency and severity. Experimental evidence suggests that hyperinsulinemia may sensitize TRPV1 receptors on trigeminal neurons and enhance CGRP release, potentially lowering the activation threshold for migraine attacks; however, direct confirmation of this pathway in humans remains limited. Furthermore, migraine with aura is linked to a doubled risk of ischemic stroke and increased risk of cardiovascular events. In pregnancy, migraine is an independent risk factor for stroke, myocardial infarction, and spontaneous coronary artery dissection. Conclusions: Migraine is a critical marker for cardiovascular and metabolic risk, necessitating routine screening and multidisciplinary management. Clinicians must prioritize cardiovascular counselling, metabolic evaluations, and careful monitoring in these patients, especially during pregnancy. Hormonal therapy choices should be individualized, preferring progestin-only contraceptives for those with aura and transdermal routes for hormone replacement therapy to minimize cardiometabolic impact. Full article

Thaw settlement (TS) in warm and ice-rich permafrost presents a challenge to highway subgrade stability in the Qinghai–Tibet Engineering Corridor (QTEC). To conduct a regional risk assessment, this study develops a framework coupling multi-source data fusion with Random Forest (RF) machine learning. By connecting site-specific thermo-mechanical simulations with corridor-scale remote sensing predictors, a 30 m resolution thaw settlement zoning map for 13 m wide separated subgrades was generated. The results indicate the following: (1) Thaw settlement exhibits significant spatial variability, with Level III settlement (20–30 cm) being the dominant category, accounting for 40.85% of the total area; Level IV and V settlements are mainly distributed in warm and ice-rich permafrost regions such as the Chumar River, Wuli, and Tuotuo River areas. (2) Mean annual ground temperature (MAGT) and ice content type (ICT) are key factors influencing the spatial settlement pattern, with differentiated dominant mechanisms: 50% of the zones are dominated by ICT, corresponding to higher settlement (26.76–43.31 cm); 35.71% are influenced by both MAGT and ICT; and 14.29% are dominated by MAGT, with lower settlement (16.23–24.19 cm). This suggests a distinct spatial pattern where “high-temperature zones are largely controlled by ice content, while low-temperature zones are controlled by temperature.” (3) Among multi-source remote sensing factors, land surface temperature (LST) and the thawing index (TI) show significant correlations with thaw settlement, confirming their applicability for hazard identification in high-altitude regions. This study provides a scientific reference and decision support for engineering maintenance and route selection on the Qinghai–Tibet Plateau. Full article

Scedosporium apiospermum is an emerging filamentous fungus of increasing clinical relevance in human and veterinary medicine. Previously regarded as a ubiquitous soil saprophyte, it is now recognized as an opportunistic pathogen causing a wide spectrum of localized and systemic infections, particularly in immunocompromised hosts. Although infections in animals are considered rare, they are likely underdiagnosed or misidentified as aspergillosis or fusariosis due to overlapping clinical features and morphological similarities. The first confirmed animal isolate of S. apiospermum in the Western Balkans, identified in 2024 from the milk of a cow with clinical mastitis, highlights the need for increased awareness and accurate diagnostic approaches for this neglected pathogen in veterinary practice. This review outlines key information on S. apiospermum infections in animals, including routes of infection, predisposing factors, clinical and pathological features, laboratory diagnostic principles, and antifungal susceptibility profiles of animal-derived isolates. Additionally, we present a chronologically organized, tabulated overview of documented cases of scedosporiosis in domestic animals, highlighting the diversity of affected species and the variability in treatment outcomes. This review aims to support early recognition, facilitate differential diagnosis, and contribute to improved management of S. apiospermum infections in veterinary practice. Full article

Polymer–ceramic composites based on cyanate ester resins have attracted increasing attention for high-frequency electronic applications due to their low dielectric loss, thermal stability, and dimensional reliability; however, achieving a targeted dielectric constant while maintaining low loss remains a key challenge. In this study, transparent glass powders and BaTiO₃ ceramic fillers were incorporated into a cyanate ester matrix to systematically investigate structure–property relationships and optimize dielectric performance for antenna-related applications. Transparent glass powders were synthesized via a melt-quenching route and combined with submicron BaTiO₃ particles, while both fillers were surface-modified using 3-triethoxysilylpropyl isocyanate (TESPI) to enhance interfacial compatibility. Composite samples containing 5–30 wt% total filler were fabricated and characterized by XRD, FTIR, tensile testing, dielectric measurements, and SEM/EDX analyses. The results demonstrate that TESPI surface modification promotes strong interfacial bonding and homogeneous filler dispersion within the cyanate ester matrix. An optimal balance between mechanical integrity and dielectric performance was achieved at 15 wt% total filler loading (K3), exhibiting a dielectric constant close to 10 and the lowest dielectric loss (tan δ ≈ 0.0047 at 1 MHz). Microstructural observations confirm that excessive filler loading leads to agglomeration and increased dielectric loss. Overall, the combined use of transparent glass and BaTiO₃ fillers, together with effective interfacial engineering, enables precise tuning of dielectric properties in cyanate ester composites for high-frequency electronic applications. Full article

Background/Objectives: Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is the sentinel implant-associated malignancy, illustrating how long-lived biomaterials can reshape local tissue–immune ecology. Although textured (high-surface-area) implants show the strongest epidemiologic association, the rarity of disease despite widespread exposure suggests additional host modifiers. We synthesize evidence supporting a gene–environment (G × E) framework and critically appraise emerging host-susceptibility signals (including BRCA1/BRCA2 and HLA associations). Methods: We conducted a narrative, evidence-based synthesis of peer-reviewed epidemiologic and registry studies, peri-implant niche biology (biofilm/foreign-body response and cytokine milieu), tumor genomic profiling, and current guidelines/regulatory communications, prioritizing primary studies for key claims. Results: Textured exposure dominates risk attribution, whereas absolute-risk estimates vary with denominators, exposure ascertainment, and follow-up duration. Mechanistic studies support a chronically inflamed capsule niche. Genomic analyses repeatedly converge on JAK/STAT pathway activation with frequent co-alterations in epigenetic regulators and recurrent copy-number changes, consistent with stepwise evolution under sustained selection. Immune-evasion features—including frequent PD-L1 expression and CD274 (9p24.1) copy-number alterations—provide a plausible checkpoint route, while host-susceptibility signals remain preliminary and require multi-center, multi-ancestry replication. Conclusions: BIA-ALCL is a multistep, context-dependent lymphoma in which implant-mediated inflammation intersects with host susceptibility to enable somatic evolution and immune escape. Clinically, prevention currently relies on exposure mitigation, standardized risk communication, and symptom-driven evaluation; precision prevention will require integrative cohorts linking verified device exposure, immunogenetics, microenvironment profiling, and tumor multi-omics. Full article

Eutectic alloys stand out for their ability to combine high strength and good ductility; a behaviour rooted in their characteristic two-phase microstructure—lamellar or globular—formed at a constant solidification temperature that minimizes segregation and suppresses brittle phases. Their low interfacial energy limits microcrack propagation, while interfacial sliding and dislocation blocking at phase boundaries enhance both strength and toughness. In this work, we investigate how controlled microstructural modifications influence the behaviour of the eutectic high-entropy alloy AlCoCrFeNi2.1, composed of B2 (Ni–Al-rich) and L12 (Co–Fe–Ni-rich) phases. Because these phases exhibit distinct mechanical responses, microconstituent morphology becomes a design parameter. Powder metallurgy is the only processing route capable of providing the level of microstructural control required in this study. It preserves the rapidly solidified eutectic architecture of gas-atomised powders while allowing its intentional transformation during consolidation. Two strategies were implemented: (i) tuning the thermal–electrical input in Spark Plasma Sintering (SPS) and Electrical Resistance Sintering (ERS), and (ii) engineering the particle size distribution, including a bimodal design that enhances surface-energy-driven morphological transitions. SPS enables a gradual lamellar-to-globular evolution, whereas ERS induces ultrafast transformations governed by current intensity. The bimodal PSD significantly accelerates globularisation at lower energy input. EBSD-KAM (Electron Backscatter Diffraction—Kernel Average Misorientation) mapping identifies the lamellar B2 phase as metastable and highly strained, while globular B2 domains show reduced dislocation density. Nanoindentation confirms that intrinsic phase properties remain unchanged, whereas microhardness scales with morphology and lamellar spacing. These results demonstrate that the macroscopic mechanical response is governed by microstructure, establishing powder metallurgy as a uniquely powerful pathway for microstructure-driven design in eutectic HEAs. Full article

Real-time route guidance during disruptions in urban rail transit systems requires rapidly providing effective strategies that simultaneously alleviate congestion and account for passengers’ travel time. This study proposes an optimization framework that considers travel time, congestion perception time, and information costs, incorporating a Logit choice model with information bias to reflect passengers’ behavioral responses under disruptions. A bi-level simulation evaluation mechanism is employed to rapidly evaluate the objective functions under different guidance strategies, where a Physically Consistent Incremental Simulator, based on differential computation, achieves a 599-fold speedup while maintaining high fidelity with full-scale simulations (Pearson correlation > 0.96). A hybrid algorithm combining the Gray Wolf Optimizer and Adaptive Large Neighborhood Search is developed to solve the origin–destination level route guidance optimization problem. The algorithm embeds domain knowledge-based “destroy and repair” operators with a sequential repair mechanism to enable fast global search and precise local refinement. Case study results demonstrate that the framework reduces severely congested sections by 36%, shortens average travel time by 7.16 min, and improves solution quality by 12–30% over baseline algorithms. These findings confirm the practical applicability of integrating intelligent optimization with high-efficiency simulation for emergency route guidance in large-scale metro networks. Full article