Search Results (4)

We present a methodology that enables dance tempo estimation through the acquisition of 3D accelerometer signals using a single wearable inertial device positioned on the dancer’s leg. Our tempo estimation method is based on enhanced multiple resonators, implemented with comb feedback filters. To validate the methodology, we focus on the versatile solo jazz dance style. Including a variety of dance moves, with different leg activation patterns and rhythmical variations, solo jazz provides for a highly critical validation environment. We consider 15 different solo jazz dance moves, with different leg activation patterns, assembled in a sequence of 5 repetitions of each, giving 65 moves altogether. A professional and a recreational dancer performed this assembly in a controlled environment, following eight dancing tempos, dictated by a metronome, and ranging from 80 bpm to 220 bpm with 20 bpm increment steps. We show that with appropriate enhancements and using single leg signals, the comb filter bank provides for accurate dance tempo estimates for all moves and rhythmical variations considered. Dance tempo estimates for the overall assembles match strongly the dictated tempo—the difference being at most 1 bpm for all measurement instances is within the limits of the established beat onset stability of the used metronome. Results further show that this accuracy is achievable for shorter dancing excerpts, comprising four dance moves, corresponding to one music phrase, and as such enables real-time feedback. By providing for a dancer’s tempo quality and consistency assessment, the presented methodology has the potential of supporting the learning process, classifying individual level of experience, and assessing overall performance. It is extendable to other dance styles and sport motion in general where cyclical patterns occur. Full article

Chronobiology is the scientific discipline which considers biological phenomena in relation to time, which assumes itself biological identity. Many physiological processes are cyclically regulated by intrinsic clocks and many pathological events show a circadian time-related occurrence. Even the pituitary–thyroid axis is under the control of a central clock, and the hormones of the pituitary–thyroid axis exhibit circadian, ultradian and circannual rhythmicity. This review, after describing briefly the essential principles of chronobiology, will be focused on the results of personal experiences and of other studies on this issue, paying particular attention to those regarding the thyroid implications, appearing in the literature as reviews, metanalyses, original and observational studies until 28 February 2021 and acquired from two databases (Scopus and PubMed). The first input to biological rhythms is given by a central clock located in the suprachiasmatic nucleus (SCN), which dictates the timing from its hypothalamic site to satellite clocks that contribute in a hierarchical way to regulate the physiological rhythmicity. Disruption of the rhythmic organization can favor the onset of important disorders, including thyroid diseases. Several studies on the interrelationship between thyroid function and circadian rhythmicity demonstrated that thyroid dysfunctions may affect negatively circadian organization, disrupting TSH rhythm. Conversely, alterations of clock machinery may cause important perturbations at the cellular level, which may favor thyroid dysfunctions and also cancer. Full article

We present the development and evaluation of a gamified rhythmic dictation application for music theory learning. The application was developed as a web application in the existing Troubadour platform for music ear training. The focus of the developed application was on user experience and engagement. With regards to the former, we developed a responsive and intuitive user interface; for the latter, we included several gamification elements and assessed the impact on the students’ engagement. We report on students’ experience analysis done through questionnaires and background data collected through the platform. We evaluated the rhythmic dictation application with the conservatory-level music theory students through A/B testing in order to independently evaluate the application’s impact. The results show a significant impact of the application on the students’ exam scores. Full article

Pulmonary delivery of nanomedicines has been extensively studied in recent years because of their enhanced biocompatibility, sustained-release properties, and surface modification capability. The lung as a target also offers many advantages over other routers, such as large surface area, noninvasive, quick therapeutic onset, and avoiding first-pass metabolism. However, nanoparticles smaller than 0.26 µm typically escape phagocytosis and remain in the alveoli for a long time, leading to particle accumulation and invoking tissue responses. It is imperative to understand the behavior and fates of inhaled nanoparticles in the alveoli to reliably assess therapeutic outcomes of nanomedicines or health risk of environmental toxins. The objective of this study is to numerically investigate nanoparticle deposition in a duct-alveolar model with varying sizes of inter-alveolar septal apertures (pores). A discrete phase Lagrangian model was implemented to track nanoparticle trajectories under the influence of rhythmic wall expansion and contraction. Both temporal and spatial dosimetry in the alveoli were computed. Wall motions are essential for nanoparticles to penetrate the acinar region and deposit in the alveoli. The level of aerosol irreversibility (i.e., mixing of inhaled nanoparticles with residual air in the alveolar airspace) is determined by the particle diffusivity, which in turn, dictates the fraction of particles being exhaled out. When deposition in the upper airways was not considered, high alveolar deposition rates (74–95%) were predicted for all nanoparticles considered (1–1000 nm), which were released into the alveoli at the beginning of the inhalation. The pore size notably affects the deposition pattern of inhaled nanoparticles but exerts a low impact upon the total deposition fractions. This finding indicates that consistent pulmonary doses of nanomedicine are possible in emphysema patients if breathing maneuver with the same tidal volume can be performed. Full article