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19 Results Found

  • Review
  • Open Access
10 Citations
6,881 Views
16 Pages

Curcumin (CCM) is a polyphenol compound extracted from the turmeric rhizome. It has various biological activities, including antibacterial, anti-inflammatory, anti-cancer, and antioxidant. Due to its diverse activities, it is often used by researcher...

  • Article
  • Open Access
5 Citations
1,925 Views
19 Pages

18 November 2023

This study emphasizes the importance of seed quality in the context of yield formation. Based on the research data, this paper emphasizes the role of proper diagnosis of seed-borne pathogens in ensuring high and stable grain yields. Particular attent...

  • Review
  • Open Access
6 Citations
3,140 Views
26 Pages

Oral Nanoformulations in Cardiovascular Medicine: Advances in Atherosclerosis Treatment

  • Xu Sun,
  • Xushuang Jia,
  • Zhaolin Tan,
  • Dongmei Fan,
  • Meiqi Chen,
  • Ning Cui,
  • Aidong Liu and
  • Da Liu

Atherosclerosis (AS) is the formation of atherosclerotic plaques on the walls of the arteries, causing them to narrow. If this occurs in the coronary arteries, the blood vessels may be completely blocked, resulting in myocardial infarction; if it occ...

  • Review
  • Open Access
10 Citations
3,600 Views
15 Pages

Recent Progress of Preparation Strategies in Organic Nanoparticles for Cancer Phototherapeutics

  • Quanquan Xie,
  • Jiayi Tang,
  • Shengze Guo,
  • Qi Zhao and
  • Shengliang Li

13 August 2023

Phototherapy has the advantages of being a highly targeted, less toxic, less invasive, and repeatable treatment, compared with conventional treatment methods such as surgery, chemotherapy, and radiotherapy. The preparation strategies are significant...

  • Review
  • Open Access
85 Citations
15,775 Views
15 Pages

Quercetin in the Prevention and Treatment of Coronavirus Infections: A Focus on SARS-CoV-2

  • Amin Gasmi,
  • Pavan Kumar Mujawdiya,
  • Roman Lysiuk,
  • Mariia Shanaida,
  • Massimiliano Peana,
  • Asma Gasmi Benahmed,
  • Nataliya Beley,
  • Nadiia Kovalska and
  • Geir Bjørklund

25 August 2022

The COVID-19 outbreak seems to be the most dangerous challenge of the third millennium due to its highly contagious nature. Amongst natural molecules for COVID-19 treatment, the flavonoid molecule quercetin (QR) is currently considered one of the mos...

  • Review
  • Open Access
17 Citations
5,507 Views
27 Pages

Molecule(s) of Interest: I. Ionic Liquids–Gateway to Newer Nanotechnology Applications: Advanced Nanobiotechnical Uses’, Current Status, Emerging Trends, Challenges, and Prospects

  • Riaz A. Khan,
  • Hamdoon A. Mohammed,
  • Ghassan M. Sulaiman,
  • Amal Al Subaiyel,
  • Arjunan Karuppaiah,
  • Habibur Rahman,
  • Sifiso Makhathini,
  • Poornima Ramburrun and
  • Yahya E. Choonara

18 November 2022

Ionic liquids are a potent class of organic compounds exhibiting unique physico-chemical properties and structural compositions that are different from the classical dipolar organic liquids. These molecules have found diverse applications in differen...

  • Review
  • Open Access
11 Citations
3,159 Views
23 Pages

10 November 2022

Cantharidin (CTD) is the main active ingredient isolated from Mylabris, and norcantharidin (NCTD) is a demethylated derivative of CTD, which has similar antitumor activity to CTD and lower toxicity than CTD. However, the clinical use of NCTD is limit...

  • Review
  • Open Access
19 Citations
5,007 Views
20 Pages

Strategies and Mechanism in Reversing Intestinal Drug Efflux in Oral Drug Delivery

  • Rong Lu,
  • Yun Zhou,
  • Jinqian Ma,
  • Yuchen Wang and
  • Xiaoqing Miao

Efflux transporters distributed at the apical side of human intestinal epithelial cells actively transport drugs from the enterocytes to the intestinal lumen, which could lead to extremely poor absorption of drugs by oral administration. Typical inte...

  • Article
  • Open Access
3 Citations
1,393 Views
19 Pages

Aerated Concrete, Based on the Ash of Thermal Power Plants, Nanostructured with Water-Soluble Fullerenols

  • Olga V. Rudenko,
  • Nikolay A. Charykov,
  • Natalya A. Kulenova,
  • Marzhan A. Sadenova,
  • Darya K. Anop and
  • Erzhan Kuldeyev

1 October 2024

This study is devoted to the synthesis of aerated concrete by a non-autoclave method using ash from thermal power plants and a nanopreparation. Fullerenol-m was used as a nanopreparation. The fullerenol-m content in the sealing water of aerated concr...

  • Review
  • Open Access
11 Citations
4,465 Views
33 Pages

Recent Advances in Nanotechnology-Based Targeted Delivery Systems of Active Constituents in Natural Medicines for Cancer Treatment

  • Yu Hu,
  • Jizheng Song,
  • Anjie Feng,
  • Jieyu Li,
  • Mengqi Li,
  • Yu Shi,
  • Wenxiu Sun and
  • Lingjun Li

24 November 2023

Owing to high efficacy and safety, natural medicines have found their way into the field of cancer therapy over the past few decades. However, the effective ingredients of natural medicines have shortcomings of poor solubility and low bioavailability...

  • Review
  • Open Access
95 Citations
14,262 Views
18 Pages

22 June 2019

With the rapid development of nano-preparation processes, nanocrystalline materials have been widely developed in the fields of mechanics, electricity, optics, and thermal physics. Compared to the case of coarse-grained or amorphous materials, plasti...

  • Review
  • Open Access
22 Citations
7,081 Views
18 Pages

Lactoferrin and Nanotechnology: The Potential for Cancer Treatment

  • Tuan Hiep Tran,
  • Phuong Thi Thu Tran and
  • Duy Hieu Truong

Lactoferrin (Lf)—a glycoprotein of the transferrin family—has been investigated as a promising molecule with diverse applications, including infection inhibition, anti-inflammation, antioxidant properties and immune modulation. Along with...

  • Article
  • Open Access
1,444 Views
18 Pages

Research and Possible Agronomic Applications of C60(OH)24 Adducts with Heavy Metals for Crop Treatment

  • Natalia A. Kulenova,
  • Nikolay A. Charykov,
  • Viktor A. Keskinov,
  • Anastasiia A. Gur’eva,
  • Valeriia P. German and
  • Dmitry G. Letenko

2 December 2023

This article describes the synthesis of fullerenol—C60(OH)24 adducts with some heavy metals—C60(ONa)x(O2Me)(24−x)/2;C60(ONa)x(O3Me)(24−x)/3; Me=Co; Cu; Mn; Zn; Gd; Tb. The identification of adducts was carried out by the metho...

  • Review
  • Open Access
3 Citations
2,568 Views
26 Pages

Mechanisms of Copper-Induced Autophagy and Links with Human Diseases

  • Yuanyuan Fu,
  • Shuyan Zeng,
  • Zhenlin Wang,
  • Huiting Huang,
  • Xin Zhao and
  • Min Li

15 January 2025

As a structural and catalytic cofactor, copper is involved in many biological pathways and is required for the biochemistry of all living organisms. However, excess intracellular copper can induce cell death due to its potential to catalyze the gener...

  • Article
  • Open Access
26 Citations
3,712 Views
15 Pages

Co-Delivery of siRNA and Chemotherapeutic Drug Using 2C5 Antibody-Targeted Dendrimer-Based Mixed Micelles for Multidrug Resistant Cancers

  • Satya Siva Kishan Yalamarty,
  • Nina Filipczak,
  • Xiang Li,
  • Tanvi Vinod Pathrikar,
  • Colin Cotter and
  • Vladimir P. Torchilin

Multidrug resistance (MDR) observed in tumors significantly hinders the efficacy of chemotherapy. Downregulation of efflux proteins, such as P-glycoprotein (P-gp), using small interfering RNA (siRNA) can be an effective way to minimize the resistance...

  • Article
  • Open Access
6 Citations
2,377 Views
15 Pages

12 November 2020

Low-density lipoprotein (LDL) preparations of the chosen polyphenols (PPs) were prepared for the first time in the literature. The solubility of the PPs in the lipidic core of the LDL increased with the increase of their lipophilicity. The anti-/pro-...

  • Article
  • Open Access
3 Citations
2,380 Views
20 Pages

15 September 2023

Overconsumption of high-fat foods increases the risk of fatty liver disease (FLD) and liver cancer with long pathogenic cycles. It is also known that the intake of the chemical poison nitrosamine and its nanopreparations can promote the development o...

  • Article
  • Open Access
455 Views
23 Pages

Ginseng-Derived Carbon Quantum Dots Enhance Systemic Exposure of Bioactive Ginsenosides and Amplify Energy Metabolism in Mice

  • Huiqiang Liu,
  • Xin Sun,
  • Bo Yang,
  • Chuan Lin,
  • Xiwu Zhang,
  • Hui Sun,
  • Xiangcai Meng,
  • Yufeng Bai,
  • Tao Zhang and
  • Guangli Yan
  • + 2 authors

Objective: To overcome the extremely low oral bioavailability of ginsenosides in traditional ginseng preparations, this study aimed to evaluate the efficacy of a novel ginseng-derived carbon quantum dots (G-CQDs) delivery system and to elucidate its...

  • Article
  • Open Access
1,346 Views
18 Pages

Effect of Selenium–Arabinogalactan Nanocomposite on Environmental Bacteria

  • Elena I. Strekalovskaya,
  • Alla I. Perfileva,
  • Olga F. Vyatchina,
  • Devard I. Stom,
  • Aleksander V. Romashchenko,
  • Anna I. Kasatova,
  • Tatyana V. Kon’kova,
  • Boris G. Sukhov and
  • Konstantin V. Krutovsky

It has been previously shown that a selenium (Se) nanocomposite (NC) based on the natural polysaccharide arabinogalactan (AG) produced from Siberian larch wood (Larix sibirica Ledeb.), containing 0.000625% of Se, has antibacterial properties against...