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17 Results Found

  • Article
  • Open Access
7 Citations
2,957 Views
12 Pages

Long-Term Morbidity and Mortality after First and Recurrent Cardiovascular Events in the ARTPER Cohort

  • Marina Escofet Peris,
  • Maria Teresa Alzamora,
  • Marta Valverde,
  • Rosa Fores,
  • Guillem Pera,
  • Jose Miguel Baena-Díez and
  • Pere Toran

16 December 2020

Background: Cardiovascular events are a major cause of mortality and morbidity worldwide. The risk of recurrence after a first cardiovascular event has been documented in the international literature, although not as extensively in a Mediterranean po...

  • Article
  • Open Access
38 Citations
4,528 Views
12 Pages

Expression of miR-1-3p, miR-16-5p and miR-122-5p as Possible Risk Factors of Secondary Cardiovascular Events

  • Rafał Badacz,
  • Paweł Kleczyński,
  • Jacek Legutko,
  • Krzysztof Żmudka,
  • Jacek Gacoń,
  • Tadeusz Przewłocki and
  • Anna Kabłak-Ziembicka

Ischemic event in one arterial territory increases the risk of a subsequent ischemic event. Circulating microRNAs (miRs) emerge as a potential clinical tool to assess risk of subsequent atherothrombotic events such as cardiovascular death (CVD), myoc...

  • Article
  • Open Access
9 Citations
2,779 Views
11 Pages

MicroRNA-134-5p and the Extent of Arterial Occlusive Disease Are Associated with Risk of Future Adverse Cardiac and Cerebral Events in Diabetic Patients Undergoing Carotid Artery Stenting for Symptomatic Carotid Artery Disease

  • Rafał Badacz,
  • Tadeusz Przewłocki,
  • Piotr Pieniążek,
  • Agnieszka Rosławiecka,
  • Paweł Kleczyński,
  • Jacek Legutko,
  • Krzysztof Żmudka and
  • Anna Kabłak-Ziembicka

12 April 2022

There is little known about the prognostic value of serum microRNAs (miRs) in diabetic patients with symptomatic internal carotid artery disease (ICAS) who underwent stent supported angioplasty (PTA) for ICAS. The present study aimed to investigate e...

  • Systematic Review
  • Open Access
5 Citations
3,707 Views
12 Pages

Beta-Blockers in Patients with Myocardial Infarction and Preserved Left Ventricular Ejection: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

  • Michael Sabina,
  • Shrinand Shah,
  • Mason Grimm,
  • Jean Carlo Daher,
  • Paola Campillo,
  • Mohammed Baraa Boozo,
  • Ahmad Al-Abdouh,
  • Waiel Abusnina,
  • Fabrizio D’ Ascenzo and
  • Anas Bizanti

30 December 2024

Background: The benefit of beta-blockers (BBs) for myocardial infarction (MI) patients with a preserved left ventricular ejection fraction (LVEF) is uncertain. While beneficial for a reduced LVEF, their efficacy with a preserved LVEF, especially with...

  • Article
  • Open Access
5 Citations
4,066 Views
13 Pages

Impact of Concomitant Use of Proton Pump Inhibitors and Clopidogrel on Recurrent Stroke and Myocardial Infarction

  • Yong Kang Lee,
  • Hyun Sun Lim,
  • Youn I Choi,
  • Eun Ju Choe,
  • Seonji Kim,
  • Seng Chan You,
  • Kyung Joo Lee,
  • Yerim Kim,
  • Da Hee Park and
  • Woon Geon Shin
  • + 1 author

28 August 2023

Background/Aims: Conflicting results have been reported regarding the interaction between proton pump inhibitors (PPIs) and clopidogrel. We investigated whether concomitant PPI use influenced the risk of recurrence in patients with stroke and myocard...

  • Article
  • Open Access
6 Citations
3,872 Views
12 Pages

Target Low-Density Lipoprotein-Cholesterol and Secondary Prevention for Patients with Acute Myocardial Infarction: A Korean Nationwide Cohort Study

  • Ju Hyeon Kim,
  • Jung-Joon Cha,
  • Subin Lim,
  • Jungseok An,
  • Mi-Na Kim,
  • Soon Jun Hong,
  • Hyung Joon Joo,
  • Jae Hyoung Park,
  • Cheol Woong Yu and
  • Do-Sun Lim
  • + 8 authors

Although lowering low-density lipoprotein cholesterol (LDL-C) levels following acute myocardial infarction (MI) is the cornerstone of secondary prevention, the attainment of recommended LDL-C goals remains suboptimal in real-world practice. We sought...

  • Article
  • Open Access
2 Citations
2,184 Views
16 Pages

Comparison of 3-Year Outcomes between Early and Delayed Invasive Strategies in Older and Younger Adults with Non-ST-Segment Elevation Myocardial Infarction Undergoing New-Generation Drug-Eluting Stent Implantation

  • Yong Hoon Kim,
  • Ae-Young Her,
  • Seung-Woon Rha,
  • Cheol Ung Choi,
  • Byoung Geol Choi,
  • Ji Bak Kim,
  • Soohyung Park,
  • Dong Oh Kang,
  • Ji Young Park and
  • Sang-Ho Park
  • + 1 author

16 August 2022

We evaluated the 3-year clinical outcomes of early invasive (EI) and delayed invasive (DI) strategies in older and younger adults with non-ST-segment elevation myocardial infarction (NSTEMI) undergoing successful new-generation drug-eluting stent (DE...

  • Article
  • Open Access
1,564 Views
14 Pages

Clinical Impact of Self-Recognition of Recurrent Acute Myocardial Infarction: From KRMI-RCC

  • Kyehwan Kim,
  • Moojun Kim,
  • Chang-Ok Seo,
  • Hangyul Kim,
  • Hye Ree Kim,
  • Min Gyu Kang,
  • Jin-Sin Koh,
  • Jeong Rang Park,
  • Rock Bum Kim and
  • Dong Ryeol Ryu
  • + 13 authors

16 August 2024

Background/Objectives: Self-recognition of recurrent myocardial infarction (re-MI) may be essential for reducing prehospital time contrast to awareness of re-MI symptoms. However, data on the current status and clinical impact of self-recognition of...

  • Article
  • Open Access

Circulating miR-223-3p as an Independent Biomarker of Recurrent Thrombotic Risk After Ischemic Stroke

  • Bence Balczó,
  • Katalin Maricza,
  • Krisztina Molnár,
  • Zsuzsanna Elek,
  • Zsófia Bánlaki,
  • Réka Kovács-Nagy,
  • Gergely Keszler,
  • Zsolt Rónai,
  • Abigél Molnár and
  • Tihamér Molnár

Background: Circulating microRNAs (miRNAs) have emerged as potential biomarkers of platelet reactivity and thrombotic risk. Among them, miR-223-3p regulates P2Y12 receptor expression and may influence response to antiplatelet therapy. This study aime...

  • Article
  • Open Access
2 Citations
2,548 Views
11 Pages

Kidney Failure among Patients with Takotsubo Syndrome or Myocardial Infarction: A Retrospective Analysis

  • Verena Bill,
  • Ibrahim El-Battrawy,
  • Marvin Kummer,
  • Andreas Mügge,
  • Assem Aweimer,
  • Michael Behnes and
  • Ibrahim Akin

Background: Takotsubo syndrome (TTS) is a syndrome with ambiguous pathophysiology. Impaired kidney function (KF) seems to impact the outcome of patients with TTS. We hypothesized that KF worsens the outcome among TTS patients and furthermore, TTS pat...

  • Systematic Review
  • Open Access
2,168 Views
30 Pages

Do SGLT2 Inhibitors Improve Cardiovascular Outcomes After Acute Coronary Syndrome Regardless of Diabetes? A Systematic Review and Meta-Analysis

  • Ioana Maria Suciu,
  • Silvia Ana Luca,
  • Simina Crișan,
  • Alina-Ramona Cozlac,
  • Svetlana Stoica,
  • Constantin Tudor Luca,
  • Bogdan Timar and
  • Dan Gaita

17 October 2025

Background and Objectives: This systematic review and meta-analysis aims to evaluate whether the benefits of sodium–glucose co-transporter-2 (SGLT2) inhibitors on cardiovascular outcomes extend when initiated in patients with acute coronary syn...

  • Article
  • Open Access
27 Citations
3,751 Views
12 Pages

MiR-126-3p and MiR-223-3p as Biomarkers for Prediction of Thrombotic Risk in Patients with Acute Myocardial Infarction and Primary Angioplasty

  • Milan Hromadka,
  • Zuzana Motovska,
  • Ota Hlinomaz,
  • Petr Kala,
  • Frantisek Tousek,
  • Jiri Jarkovsky,
  • Marketa Beranova,
  • Pavel Jansky,
  • Michal Svoboda and
  • Iveta Krepelkova
  • + 3 authors

Aim. This study was designed to evaluate the relationship between microRNAs (miRNAs), miR-126-3p and miR-223-3p, as new biomarkers of platelet activation, and predicting recurrent thrombotic events after acute myocardial infarction (AMI). Methods and...

  • Article
  • Open Access
5 Citations
2,701 Views
15 Pages

Left Ventricular Ejection Fraction Association with Acute Ischemic Stroke Outcomes in Patients Undergoing Thrombolysis

  • Ryan C. H. Chee,
  • Norman H. Lin,
  • Jamie S. Y. Ho,
  • Aloysius S. T. Leow,
  • Tony Y. W. Li,
  • Edward C. Y. Lee,
  • Mark Y. Chan,
  • William K. F. Kong,
  • Tiong-Cheng Yeo and
  • Ping Chai
  • + 6 authors

(1) Background: Little is known about how left ventricular systolic dysfunction (LVSD) affects functional and clinical outcomes in acute ischemic stroke (AIS) patients undergoing thrombolysis; (2) Methods: A retrospective observational study conducte...

  • Article
  • Open Access
14 Citations
2,522 Views
17 Pages

Association between the Changes in Trimethylamine N-Oxide-Related Metabolites and Prognosis of Patients with Acute Myocardial Infarction: A Prospective Study

  • Nan Li,
  • Ying Wang,
  • Jinying Zhou,
  • Runzhen Chen,
  • Jiannan Li,
  • Xiaoxiao Zhao,
  • Peng Zhou,
  • Chen Liu,
  • Yi Chen and
  • Li Song
  • + 3 authors

This study aimed to investigate the association between changes in levels of trimethylamine N-oxide (TMAO) and its precursors and the prognosis of patients with acute myocardial infarction (AMI). Patients diagnosed with AMI were prospectively enrolle...

  • Article
  • Open Access
6 Citations
2,641 Views
17 Pages

Prognostic Impacts of LL-37 in Relation to Lipid Profiles of Patients with Myocardial Infarction: A Prospective Cohort Study

  • Runzhen Chen,
  • Hanjun Zhao,
  • Jinying Zhou,
  • Ying Wang,
  • Jiannan Li,
  • Xiaoxiao Zhao,
  • Nan Li,
  • Chen Liu,
  • Peng Zhou and
  • Yi Chen
  • + 2 authors

14 October 2022

Background. In vivo studies show that LL-37 inhibits the progression of atherosclerosis and predicts a lower risk of recurrent ischemia in patients with acute myocardial infarction (AMI), which could be mediated by the modulation of lipid metabolism....

  • Article
  • Open Access
2 Citations
3,559 Views
14 Pages

(1) Background. One of the causes of myocardial infarction (MI) with nonobstructive coronary arteries (MINOCA) is thrombus formation in situ followed by lysis, resulting in a morphologically normal angiogram but with an underlying prothrombotic state...

  • Article
  • Open Access
12 Citations
4,029 Views
15 Pages

Prognostic Value of Incomplete Revascularization after Percutaneous Coronary Intervention Following Acute Coronary Syndrome: Focus on CKD Patients

  • Thomas Cardi,
  • Anas Kayali,
  • Antonin Trimaille,
  • Benjamin Marchandot,
  • Jessica Ristorto,
  • Viet Anh Hoang,
  • Sébastien Hess,
  • Marion Kibler,
  • Laurence Jesel and
  • Patrick Ohlmann
  • + 1 author

Background: Residual coronary artery disease (CAD) has been associated with worsened prognosis in patients undergoing percutaneous coronary intervention (PCI) for acute coronary syndromes (ACS). The residual SYNTAX Score (rSS) aims to assess residual...