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Search Results (698)

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Keywords = modified gravity

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5 pages, 195 KB  
Editorial
Modified Gravity: From Black Holes Entropy to Current Cosmology, 4th Edition
by Kazuharu Bamba
Entropy 2026, 28(2), 222; https://doi.org/10.3390/e28020222 (registering DOI) - 14 Feb 2026
Abstract
Recent cosmological observational data—such as type Ia supernovae (SNe Ia) [...] Full article
15 pages, 349 KB  
Article
Quantum Omni-Synthesis I: Core Field-Theoretical Framework
by Stefalo Acha
Quantum Rep. 2026, 8(1), 15; https://doi.org/10.3390/quantum8010015 - 13 Feb 2026
Abstract
The Quantum Omni-Synthesis (QOS) framework is inspired by the cosmological constant problem, the dark sector, and the tension that arises when gravity is treated as purely geometrical while quantum fields remain defined on a fixed background. QOS adopts the working hypothesis that the [...] Read more.
The Quantum Omni-Synthesis (QOS) framework is inspired by the cosmological constant problem, the dark sector, and the tension that arises when gravity is treated as purely geometrical while quantum fields remain defined on a fixed background. QOS adopts the working hypothesis that the dominant components of the dark sector correspond to two complementary energetic tendencies already familiar from known physics: confining, binding-dominated behavior and dispersive, propagating behavior. For clarity of interpretation, these are referred to as implosive and explosive energy, respectively. This terminology is not intended to redefine cosmological dark matter or dark energy, but to provide an effective language for tracking how different forms of energy contribute to localization, propagation, and gravitational coupling across scales. QOS postulates that every field configuration admits a decomposition of its local energy density into these two complementary components. A dimensionless scalar quantity, the Quantized Gravity Coupling Parameter ς(x), quantifies the local fraction of implosive energy. Spacetime curvature in QOS is generated primarily by the implosive fraction, while explosive energy contributes to propagation and vacuum activity without sourcing gravity at the same strength. In this paper, a field-theoretical realization of this idea is presented for a single real scalar field. A QOS-modified Lagrangian is introduced in which the kinetic term is weighted by a factor A(ψ,ψ)=1ς2(ψ,ψ) that encodes the local balance between gradient and potential energy. From this Lagrangian, the nonlinear field equation and the corresponding energy momentum tensor are derived in full generality, including the effects of the functional dependence of A on the field and its derivatives. An effective Ricci tensor is constructed as Rμνeff=Rμν+fμν, where the correction fμν is expressed in terms of derivatives of Φ=ln(1ς2) and arises from the energetic weighting rather than an independent scalar degree of freedom. The resulting QOS field equation couples this scalar sector to curvature without introducing a separate Brans–Dicke-like field. Full article
34 pages, 489 KB  
Article
Gauge-Invariant Gravitational Wave Polarization in Metric f(R) Gravity with Cosmological Implications
by Ramesh Radhakrishnan, David McNutt, Delaram Mirfendereski, Alejandro Pinero, Eric Davis, William Julius and Gerald Cleaver
Universe 2026, 12(2), 44; https://doi.org/10.3390/universe12020044 - 5 Feb 2026
Viewed by 373
Abstract
We develop a fully gauge-invariant analysis of gravitational-wave polarizations in metric f(R) gravity with a particular focus on the modified Starobinsky model f(R)=R+αR22Λ, whose constant-curvature solution [...] Read more.
We develop a fully gauge-invariant analysis of gravitational-wave polarizations in metric f(R) gravity with a particular focus on the modified Starobinsky model f(R)=R+αR22Λ, whose constant-curvature solution Rd=4Λ provides a natural de Sitter background for both early- and late-time cosmology. Linearizing the field equations around this background, we derive the Klein–Gordon equation for the curvature perturbation δR and show that the scalar propagating mode acquires a mass mψ2=1/(6α), highlighting how the same scalar degree of freedom governs inflationary dynamics at high curvature and the propagation of gravitational waves in the current accelerating Universe. Using the scalar–vector–tensor decomposition and a decomposition of the perturbed Ricci tensor, we obtain a set of fully gauge-invariant propagation equations that isolate the contributions of the scalar, vector, and tensor modes in the presence of matter. We find that the tensor sector retains the two transverse–traceless polarizations of General Relativity, while the scalar sector contains an additional massive scalar propagating degree of freedom, which manifests through breathing and longitudinal tidal responses depending on the wave regime and detector frame. Through the geodesic deviation equation—computed both in a local Minkowski patch and in fully covariant de Sitter form—we independently recover the same polarization content and identify its tidal signatures. The resulting framework connects the extra scalar polarization to cosmological observables: the massive scalar propagating mode sets the range of the fifth force, influences the time evolution of gravitational potentials, and affects the propagation and dispersion of gravitational waves on cosmological scales. This provides a unified, gauge-invariant link between gravitational-wave phenomenology and the cosmological implications of metric f(R) gravity. Full article
(This article belongs to the Section Gravitation)
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33 pages, 4987 KB  
Article
Analysis of the Driving Mechanism of China’s Provincial Carbon Emission Spatial Correlation Network: Based on the Dual Perspectives of Dynamic Evolution and Static Formation
by Jie-Kun Song, Yang Ding, Hui-Sheng Xiao and Yi-Long Su
Systems 2026, 14(2), 163; https://doi.org/10.3390/systems14020163 - 3 Feb 2026
Viewed by 218
Abstract
Against the backdrop of China’s commitment to achieving carbon peaking by 2030 and carbon neutrality by 2060, inter-provincial carbon emissions form a complex interconnected spatial network—clarifying its operational mechanisms is crucial for optimizing regional carbon reduction strategies. Based on 2006–2021 data from 30 [...] Read more.
Against the backdrop of China’s commitment to achieving carbon peaking by 2030 and carbon neutrality by 2060, inter-provincial carbon emissions form a complex interconnected spatial network—clarifying its operational mechanisms is crucial for optimizing regional carbon reduction strategies. Based on 2006–2021 data from 30 Chinese provinces, this study constructs the China Provincial Carbon Emission Spatial Correlation Network (CPCESCN) using a modified gravity model. Social Network Analysis (SNA) explores its structural characteristics, while motif and QAP correlation analyses identify endogenous structural and attribute variables. Innovatively integrating Exponential Random Graph Models (ERGM) and Stochastic Actor-Oriented Models (SAOM), it investigates the network’s static formation mechanisms and dynamic evolution drivers. Results show CPCESCN has a stable multi-threaded structure without isolated nodes, with Jiangsu, Guangdong, Shandong, Zhejiang, Henan, and Sichuan as high-centrality core nodes with high centrality. GDP, green technology innovation, urbanization rate, industrialization rate, energy consumption intensity, and environmental regulations significantly influence network dynamics, with reciprocal relationships as key endogenous drivers. While geographic proximity still facilitates network formation, its impact has weakened notably, and functional complementarity has become the dominant evolutionary driver—based on the findings, policy suggestions are proposed, including deepening inter-provincial functional cooperation, implementing differentiated carbon reduction policies, and optimizing multi-dimensional low-carbon transformation systems. Full article
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14 pages, 543 KB  
Article
Clusters of PBHs in a Framework of Multidimensional f(R)-Gravity
by Maxim Krasnov and Valery Nikulin
Particles 2026, 9(1), 12; https://doi.org/10.3390/particles9010012 - 3 Feb 2026
Viewed by 208
Abstract
We investigate primordial black hole (PBH) production via the collapse of supercritical domain walls in a quadratic f(R)-gravity model with tensor extensions. The effective field theory for an extra space’s scalar curvature provides a foundation for the formation of [...] Read more.
We investigate primordial black hole (PBH) production via the collapse of supercritical domain walls in a quadratic f(R)-gravity model with tensor extensions. The effective field theory for an extra space’s scalar curvature provides a foundation for the formation of these dense walls. In our work, domain walls are found to be supercritical. Their properties were extensively studied in the literature, where it was demonstrated that they create wormholes and escape into baby universes through them. Closure of the wormhole leads to black hole creation, providing a mechanism for the production of primordial black holes in our model. We calculate the mass spectrum of such black holes and mass distribution within clusters of them. When accretion is accounted for, the black holes produced under this mechanism present viable dark matter candidates. Full article
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34 pages, 21530 KB  
Article
Understanding the Universe Without Dark Matter and Without the Need to Modify Gravity: Is the Universe an Anamorphic Structure?
by Gianni Pascoli and Louis Pernas
Symmetry 2026, 18(2), 234; https://doi.org/10.3390/sym18020234 - 28 Jan 2026
Viewed by 312
Abstract
We envision a minimalist way to explain a number of astronomical facts associated with the unsolved missing mass problem by considering a new phenomenological paradigm. In this model, no new exotic particles need to be added, and the gravity is not modified; it [...] Read more.
We envision a minimalist way to explain a number of astronomical facts associated with the unsolved missing mass problem by considering a new phenomenological paradigm. In this model, no new exotic particles need to be added, and the gravity is not modified; it is the perception that we have of a purely Newtonian (or purely Einsteinian) Universe, dubbed the Newton basis or Einstein basis (actually “viewed through a pinhole” which is “optically” distorted in some manner by a so-called magnifying effect). The κ model is not a theory but rather an exploratory technique that assumes that the sizes of the astronomical objects (galaxies and galaxy clusters or fluctuations in the CMB) are not commensurable with respect to our usual standard measurement. To address this problem, we propose a rescaling of the lengths when these are larger than some critical values, say >100 pc - 1 kpc for the galaxies and ∼1 Mpc for the galaxy clusters. At the scale of the solar system or of a binary star system, the κ effect is not suspected, and the undistorted Newtonian metric fully prevails. A key point of an ontological nature rising from the κ model is the distinction which is made between the distances depending on how they are obtained: (1) distances deduced from luminosity measurements (i.e., the real distances as potentially measured in the Newton basis, which are currently used in the standard cosmological model) and (2) even though it is not technically possible to deduce them, the distances which would be deduced by trigonometry. Those “trigonometric” distances are, in our model, altered by the kappa effect, except in the solar environment where they are obviously accurate. In outer galaxies, the determination of distances (by parallax measurement) cannot be carried out, and it is difficult to validate or falsify the kappa model with this method. On the other hand, it is not the same within the Milky Way, for which we have valuable trigonometric data (from the Gaia satellite). Interestingly, it turns out that for this particular object, there is strong tension between the results of different works regarding the rotation curve of the galaxy. At the present time, when the dark matter concept seems to be more and more illusive, it is important to explore new ideas, even the seemingly incredibly odd ones, with an open mind. The approach taken here is, however, different from that adopted in previous papers. The analysis is first carried out in a space called the Newton basis with pure Newtonian gravity (the gravity is not modified) and in the absence of dark matter-type exotic particles. Then, the results (velocity fields) are transported into the leaves of a bundle (observer space) using a universal transformation associated with the average mass density expressed in the Newton basis. This approach will make it much easier to deal with situations where matter is not distributed centrosymmetrically around a center of maximum density. As examples, we can cite the interaction of two galaxies or the case of the collision between two galaxy clusters in the bullet cluster. These few examples are difficult to treat directly in the bundle, especially since we would include time-based monitoring (with an evolving κ effect in the bundle). We will return to these questions later, as well as the concept of average mass density at a point. The relationship between this density and the coefficient κ must also be precisely defined. Full article
(This article belongs to the Special Issue Gravitational Physics and Symmetry)
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18 pages, 1994 KB  
Article
Experimental Lung Ultrasound Scoring in a Murine Model of Aspiration Pneumonia: Challenges and Diagnostic Perspectives
by Ching-Wei Chuang, Wen-Yi Lai, Kuo-Wei Chang, Chao-Yuan Chang, Shang-Ru Yeoh and Chun-Jen Huang
Diagnostics 2026, 16(2), 361; https://doi.org/10.3390/diagnostics16020361 - 22 Jan 2026
Viewed by 336
Abstract
Background: Aspiration pneumonia (AP) remains a major cause of morbidity and mortality, yet non-invasive tools for monitoring lung injury in preclinical models are limited. Lung ultrasound (LUS) is widely used clinically, but existing murine scoring systems lack anatomical resolution and have not been [...] Read more.
Background: Aspiration pneumonia (AP) remains a major cause of morbidity and mortality, yet non-invasive tools for monitoring lung injury in preclinical models are limited. Lung ultrasound (LUS) is widely used clinically, but existing murine scoring systems lack anatomical resolution and have not been validated for aspiration-related injury. Methods: We developed the Modified Lung Edema Ultrasound Score (MLEUS), a region-structured adaptation of the Mouse Lung Ultrasound Score (MoLUS), designed to accommodate the heterogeneous and gravity-dependent injury patterns characteristic of murine AP. Male C57BL/6 mice were assigned to sham, 6 h, 24 h, or 48 h groups. Regional LUS findings were compared with histological injury scores and wet-to-dry (W/D) ratios. Inter-rater reliability was assessed using the intraclass correlation coefficient (ICC). Results: Global LUS–histology correlation was weak (ρ = 0.33, p = 0.114). In contrast, regional performance varied markedly. The right upper (RU) zone showed the strongest correspondence with histological injury (r = 0.55, p = 0.005), whereas right and left diaphragmatic regions demonstrated minimal association. LUS abnormalities were detectable as early as 6 h, preceding clear histological progression. Inter-rater reliability was good (ICC = 0.87). Conclusions: MLEUS provides a reproducible, region-specific framework for evaluating aspiration-induced lung injury in mice. Although global correlations with histology were limited, region-dependent analysis identified that the RU zone as a reliable acoustic window for concurrent injury assessment. Early ultrasound changes highlight the sensitivity of LUS to dynamic aeration and interstitial alterations rather than cumulative tissue damage. These findings support the use of LUS as a complementary, non-invasive physiological monitoring tool in small-animal respiratory research and clarify its methodological scope relative to existing scoring frameworks. Full article
(This article belongs to the Special Issue Future Challenges for Lung and Liver Ultrasound)
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50 pages, 1081 KB  
Article
Guaranteed Tensor Luminality from Symmetry: A PT-Even Palatini Torsion Framework
by Chien-Chih Chen
Symmetry 2026, 18(1), 170; https://doi.org/10.3390/sym18010170 - 16 Jan 2026
Viewed by 227
Abstract
Multimessenger constraints tightly bound the gravitational-wave speed to be luminal, posing a strong filter for modified gravity. This paper develops a symmetry-selected Palatini framework with torsion in which exact luminality at quadratic order is achieved by construction rather than by parameter tuning. Two [...] Read more.
Multimessenger constraints tightly bound the gravitational-wave speed to be luminal, posing a strong filter for modified gravity. This paper develops a symmetry-selected Palatini framework with torsion in which exact luminality at quadratic order is achieved by construction rather than by parameter tuning. Two ingredients shape the observable sector: (i) a scalar PT projector that keeps scalar densities real and parity-even, and (ii) projective invariance implemented via a non-dynamical Stueckelberg compensator that enters only through its gradient. Under an explicit posture (A1–A6), we establish three structural results: (C1) algebraic uniqueness of torsion to a pure-trace form aligned with the compensator gradient; (C2) bulk equivalence, modulo improvements, among a rank-one determinant route, a closed-metric deformation, and a PT-even CS/Nieh–Yan route; and (C3) a coefficient-locking identity that enforces K=G for tensor modes on admissible domains; hence, cT=1 with two propagating polarizations. Beyond leading order, the framework yields a distinctive, falsifiable next-to-leading correction δcT2(k)=bk2/Λ2 (for kΛ), predicting slope 2 in log–log fits across frequency bands (PTA/LISA/LVK). The analysis is formulated to be reproducible, with a public repository providing figure generators, coefficients, and tests that directly validate (C1)–(C3). Full article
(This article belongs to the Special Issue Symmetry, Topology and Geometry in Physics)
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12 pages, 2342 KB  
Proceeding Paper
Study of the Influence of the Geometric Shape of Structural Elements on the Hydrodynamic Pattern in a Radial Precipitator
by Aleksandrina Bankova, Anastas Yangyozov, Stefan Tenev and Asparuh Atanasov
Eng. Proc. 2026, 122(1), 12; https://doi.org/10.3390/engproc2026122012 - 16 Jan 2026
Viewed by 188
Abstract
Wastewater treatment facilities of a diameter of approximately 15 m or more provide the opportunity to process large volumes of stormwater. The current report investigates the operation of a stormwater radial precipitator, without an impeller, working with particles of various sizes. A distinguishing [...] Read more.
Wastewater treatment facilities of a diameter of approximately 15 m or more provide the opportunity to process large volumes of stormwater. The current report investigates the operation of a stormwater radial precipitator, without an impeller, working with particles of various sizes. A distinguishing feature is that the two-phase flow is solely gravity-driven, which leads to reduced energy requirements. This entails the necessity of a facility in which the linear and the local losses are minimized as much as possible. Linear losses can be reduced by decreasing the precipitator’s size. The initially proposed 15 m diameter proved to be ineffective since the sand only reached a certain zone and could not flow further to the outlet due to the insufficient energy. Therefore, it was necessary to reduce the size of the radial precipitator, which resulted in a shorter path for the sand particles and the water, which, in turn, reduced the linear resistance. As for the local losses, it turned out that many areas of the precipitator construction could be geometrically modified to significantly reduce the energy loss of the sand–water mixture. The boundary layer cannot be removed. However, it is possible the size and the number of vortex structures inside the settler to be reduced in order to create an optimal working environment. Full article
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19 pages, 834 KB  
Article
Testing Running Vacuum Energy in f(Q) Gravity with DESI Data
by Dalale Mhamdi, Redouane El Ouardi, Ahmed Errahmani and Amine Bouali
Universe 2026, 12(1), 25; https://doi.org/10.3390/universe12010025 - 15 Jan 2026
Viewed by 247
Abstract
In this paper, we investigate the running vacuum energy (RVE) model within the framework of f(Q) gravity (f(Q)-RVE). In this context, the modified Friedmann equation can be used to establish a formal analogy with the [...] Read more.
In this paper, we investigate the running vacuum energy (RVE) model within the framework of f(Q) gravity (f(Q)-RVE). In this context, the modified Friedmann equation can be used to establish a formal analogy with the structure of the RVE. A key feature is that the vacuum equation of state is no longer fixed but receives a dynamical correction proportional to H˙ and H¨/H. We consider two cases of f(Q)-RVE, denoted as Model I (parametrized by ν) and Model II (parametrized by ν and α), corresponding to the first and second derivatives of H, respectively. The models are constrained using recent DESI BAO data in combination with Pantheon+, cosmic chronometer (CC), and CMB observations. Our analysis shows a deviation of ν from zero at a significance level of ∼1.4σ for Model I, while in Model II, ν and α deviate from zero at 0.7σ and 1.3σ, respectively, relative to ΛCDM. Furthermore, the statistical comparison based on the Akaike, Bayesian, and Deviance Information Criteria (AIC, BIC, DIC) indicates that Model I remains competitive with ΛCDM, while Model II is penalized due to its higher complexity and the sensitivity associated with the additional parameter α. Full article
(This article belongs to the Section Cosmology)
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8 pages, 431 KB  
Proceeding Paper
Compressive Strength, Density, and Setting Time of Concrete Blended with Rice Husk Ash
by Edidiong Eseme Ambrose, Okiemute Roland Ogirigbo, Tirimisiu Bayonle Bello and Saviour Umoh Akpando
Eng. Proc. 2026, 124(1), 1; https://doi.org/10.3390/engproc2026124001 - 14 Jan 2026
Viewed by 740
Abstract
This study investigated the effects of incorporating rice husk ash (RHA) as a partial replacement for cement on the properties of concrete. To determine the optimal replacement level, RHA was used to replace cement in varying proportions, ranging from 0% to 25% in [...] Read more.
This study investigated the effects of incorporating rice husk ash (RHA) as a partial replacement for cement on the properties of concrete. To determine the optimal replacement level, RHA was used to replace cement in varying proportions, ranging from 0% to 25% in 5% increments. The mix with 0% RHA served as the control. The properties evaluated included setting time, density, and compressive strength. The results revealed that blending RHA with cement increased the initial setting time. This was attributed to the lower calcium oxide (CaO2) content of RHA, which slows early-age hydration reactions. Conversely, the final setting time was reduced due to the pozzolanic activity of RHA, which enhances later-stage reactions. Additionally, the inclusion of RHA resulted in a decrease in concrete density, owing to its lower specific gravity and bulk density compared to Portland cement. Despite this, RHA-modified specimens exhibited higher compressive strengths than the control specimens. This strength enhancement was linked to the formation of additional calcium–silicate–hydrate (C-S-H) gel due to the pozzolanic reaction between amorphous silica in RHA and calcium hydroxide (CaOH) from hydration reaction. The gel fills concrete voids at the microstructural level, producing a denser and more compact concrete matrix. Based on the balance between strength and durability, the optimal RHA replacement level was identified as 10%. Full article
(This article belongs to the Proceedings of The 6th International Electronic Conference on Applied Sciences)
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24 pages, 2518 KB  
Review
A Review of Oil–Water Separation Technology for Transformer Oil Leakage Wastewater
by Lijuan Yao, Han Shi, Wen Qi, Baozhong Song, Jun Zhou, Wenquan Sun and Yongjun Sun
Water 2026, 18(2), 180; https://doi.org/10.3390/w18020180 - 9 Jan 2026
Viewed by 523
Abstract
The oily wastewater produced by transformer oil leakage contains pollutants such as mineral oil, metal particles, aged oil and additives, which can disrupt the dissolved oxygen balance in water bodies, pollute soil and endanger human health through the food chain, causing serious environmental [...] Read more.
The oily wastewater produced by transformer oil leakage contains pollutants such as mineral oil, metal particles, aged oil and additives, which can disrupt the dissolved oxygen balance in water bodies, pollute soil and endanger human health through the food chain, causing serious environmental pollution. Effective oil–water separation technology is the key to ecological protection and resource recovery. This paper reviews the principles, influencing factors and research progress of traditional (gravity sedimentation, air flotation, adsorption, demulsification) and new (nanocomposite adsorption, metal–organic skeleton materials, superhydrophobic/superlipophilic modified films) transformer oil–water separation technologies. Traditional technologies are mostly applicable to large-particle-free oil and are difficult to adapt to complex matrix wastewater. However, the new technology has significant advantages in separation efficiency (up to over 99.5%), selectivity and cycling stability (with a performance retention rate of over 85% after 20–60 cycles), breaking through the bottlenecks of traditional methods. In the future, it is necessary to develop low-cost and efficient separation technologies, promote the research and development of intelligent responsive materials, upgrade low-carbon preparation processes and their engineering applications, support environmental protection treatment in the power industry and encourage the coupling of material innovation and processes. Full article
(This article belongs to the Section Wastewater Treatment and Reuse)
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34 pages, 549 KB  
Article
Primordial Gravitational Wave Birefringence in a de Sitter Background with Chern–Simons Coupling
by Abhishek Rout and Brett Altschul
Universe 2026, 12(1), 6; https://doi.org/10.3390/universe12010006 - 26 Dec 2025
Viewed by 274
Abstract
In this work, we investigate tensor perturbations in a de Sitter background within the framework of Chern–Simons modified gravity. We introduce transverse-traceless perturbations and analyze how the Chern–Simons Cotton tensor induces parity-violating modifications to gravitational wave propagation, while the Pontryagin density vanishes at [...] Read more.
In this work, we investigate tensor perturbations in a de Sitter background within the framework of Chern–Simons modified gravity. We introduce transverse-traceless perturbations and analyze how the Chern–Simons Cotton tensor induces parity-violating modifications to gravitational wave propagation, while the Pontryagin density vanishes at linear order. Using a mode decomposition of the scalar background field, we derive the sub- and super-horizon limits of the wave equations and uncover chiral corrections in the dispersion relations of tensor modes. The resulting birefringence exhibits both amplitude and velocity components, alternating with the phase of the scalar field. Particular solutions sourced by the scalar background show helicity-dependent amplification and a characteristic scaling of the radiated flux that reduces smoothly to the Minkowski limit. The accumulated phase difference between right- and left-handed modes grows quadratically inside the horizon and becomes frozen outside, leaving a permanent parity-violating imprint in the primordial tensor spectrum. Finally, by promoting the Chern–Simons field to a massive dark matter candidate, we demonstrate how its mass-dependent dynamics connect gravitational birefringence to axion-like dark matter phenomenology. Full article
(This article belongs to the Section Gravitation)
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33 pages, 4608 KB  
Article
Simulated Microgravity-Induced Changes in SUMOylation and Protein Expression in Saccharomyces cerevisiae
by Jeremy A. Sabo and Steven D. Hartson
Int. J. Mol. Sci. 2026, 27(1), 42; https://doi.org/10.3390/ijms27010042 - 19 Dec 2025
Viewed by 520
Abstract
Microgravity during space travel induces significant regulatory changes in the body, posing health risks for astronauts, including alterations in cell morphology and cytoskeletal integrity. The Small Ubiquitin-like Modifier (SUMO) is crucial for cellular adaptation, regulating DNA repair, cytoskeletal dynamics, cell division, and protein [...] Read more.
Microgravity during space travel induces significant regulatory changes in the body, posing health risks for astronauts, including alterations in cell morphology and cytoskeletal integrity. The Small Ubiquitin-like Modifier (SUMO) is crucial for cellular adaptation, regulating DNA repair, cytoskeletal dynamics, cell division, and protein turnover—all processes affected by microgravity. To determine the extent to which SUMO mediates the cellular response to microgravity stress, Saccharomyces cerevisiae cells were cultured under normal gravity and simulated microgravity (SMG) in rotating wall vessels. After 12 h of culture, we investigated changes in SUMO modified proteins and protein expression. We identified 347 SUMOylated proteins, 18 of which demonstrated a 50% change in abundance under SMG. Of 3773 proteins identified, protein expression for 34 proteins decreased and 8 increased by over 50% in SMG (p < 0.05). Differentially expressed proteins represented changes in cellular processes for DNA repair, cell division, histone modification, and cytoskeleton regulation. These findings underscore the pivotal role of SUMOylation in orchestrating cellular adaptation to the unique stress of microgravity, revealing potential targets for mitigating spaceflight-induced health risks. Full article
(This article belongs to the Special Issue Advances in Yeast Engineering and Stress Responses)
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25 pages, 12504 KB  
Article
Study on the Spatial Association Complexity and Formation Mechanism of Green Innovation Efficiency Network for Sustainable Urban Development: Taking the Yangtze River Delta Urban Agglomeration as an Example
by Binghui Zhang, Ling Xu, Shaojun Zhong, Kailin Zeng and Wenxing Zhu
Sustainability 2025, 17(24), 11273; https://doi.org/10.3390/su172411273 - 16 Dec 2025
Viewed by 344
Abstract
Against the backdrop of China’s “dual carbon” strategy and regional integration, enhancing green innovation efficiency (GIE) has become a core issue for the Yangtze River Delta Urban Agglomeration (YRDUA) in achieving sustainable and high-quality development. This study employs the Super EBM model to [...] Read more.
Against the backdrop of China’s “dual carbon” strategy and regional integration, enhancing green innovation efficiency (GIE) has become a core issue for the Yangtze River Delta Urban Agglomeration (YRDUA) in achieving sustainable and high-quality development. This study employs the Super EBM model to measure the GIE of 41 cities in the YRDUA from 2012 to 2022 and further integrates a modified gravity model with social network analysis to uncover the structural complexity and spatial directionality of its spatial association network. In addition, the Exponential Random Graph Model (ERGM) is applied to explore the formation mechanisms of the green innovation efficiency network. Results show the following: (1) GIE presents a fluctuating upward trend, with the mean rising from 0.747 in 2012 to 0.906 in 2022 and disparities gradually narrowing, but provincial gradients persist, implying potential “Matthew effect” risks. (2) Network density continues to increase, with S-density rising from 0.0061 in 2012 to 0.0335 in 2022; supporting and basic connections serve as key drivers of network complexity, whereas the significant decline of edge connections may weaken the network’s extensibility. (3) Node connections display preference and attachment, causing polarization; transitivity and triadic cooperation rise markedly, increasing by 41.89% and 40.86%, respectively, reflecting strong self-organization. (4) Reciprocity and agglomeration drive network formation, and economic and technological differences promote it, while disparities in innovation input and government roles vary across periods. Geographic distance hinders formation, though its effect is weakening. These findings enhance the methodological approaches to sustainability research and provide insights for optimizing regional cooperation and advancing green integration in the YRDUA. Full article
(This article belongs to the Section Sustainable Urban and Rural Development)
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