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Keywords = isolated splenic metastasis

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8 pages, 3377 KiB  
Case Report
Isolated Spleen Metastases of Endometrial Cancer: A Case Report
by Marko M. Stojanovic, Vesna Brzački, Jelena D. Zivadinovic, Nebojsa S. Ignjatovic, Marko D. Gmijovic, Miodrag N. Djordjevic, Ilija Golubovic, Nada G. Nikolić, Novica Z. Bojanic and Miroslav P. Stojanovic
Medicina 2022, 58(5), 592; https://doi.org/10.3390/medicina58050592 - 26 Apr 2022
Cited by 3 | Viewed by 3115
Abstract
Background: Isolated splenic metastases from endometrial cancer, which is a relatively common malignancy, are extremely rare findings; to date, only 14 cases have been reported in the literature. Case Summary: We report a patient with isolated splenic metastases of endometrial cancer 3 years [...] Read more.
Background: Isolated splenic metastases from endometrial cancer, which is a relatively common malignancy, are extremely rare findings; to date, only 14 cases have been reported in the literature. Case Summary: We report a patient with isolated splenic metastases of endometrial cancer 3 years after radical surgery of the primary tumor. The patient was successfully treated by splenectomy and six cycles of paclitaxel. Fifty months after splenectomy, she was alive and well, and with no evidence of disease. Conclusion: Isolated spleen metastasis of endometrial cancer is very rare. Radical surgery and adjuvant therapy may offer excellent long-term survival. Full article
(This article belongs to the Section Surgery)
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9 pages, 1067 KiB  
Case Report
Isolated Splenic Metastasis of Primary Lung Cancer Presented as Metachronous Oligometastatic Disease—A Case Report
by Milorad Reljic, Boris Tadic, Katarina Stosic, Milica Mitrovic, Nikola Grubor, Stefan Kmezic, Miljan Ceranic and Vladimir Milosavljevic
Diagnostics 2022, 12(1), 209; https://doi.org/10.3390/diagnostics12010209 - 15 Jan 2022
Cited by 5 | Viewed by 2993
Abstract
Modern oncology practice and new antitumor drugs prolonged disease-free intervals in patients with lung cancer. Patients with distant metastatic disease are treated only with palliative intent. The International Association for the Study of Lung Cancer, in the 8th edition of the TNM classification, [...] Read more.
Modern oncology practice and new antitumor drugs prolonged disease-free intervals in patients with lung cancer. Patients with distant metastatic disease are treated only with palliative intent. The International Association for the Study of Lung Cancer, in the 8th edition of the TNM classification, for the first time includes oligometastatic disease as a clinical state that describes the patients with distant metastasis, limited in number and organ sites, who may have more indolent biology. In this paper, we present a case of a 56-year-old man who was admitted to our clinic regarding a radiologically diagnosed splenic lesion of uncertain nature, and who underwent a left upper lobectomy for primary lung cancer 12 years before. After a detailed radiological diagnosis, it was concluded that it is highly suspected metastatic lesion of the spleen and the patient underwent a splenectomy. While no definitive protocols exist on the management of isolated splenic metastasis from lung cancer, splenectomy, in suitable patients, with reasonable survival expectations, improves patient disease-free survival and can prevent potentially life-threatening complications, such as splenic rupture. 18F-FDG PET has very high sensitivity and specificity for differentiating benign and malignant splenic lesions especially in patients who are in the follow up protocol due to primary malignancy. Full article
(This article belongs to the Section Pathology and Molecular Diagnostics)
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