Search Results (51)

Natural and human-made disasters, community violence, climate change, and political instability engender mental health problems worldwide. Childhood traumas, now recognized as commonplace and global in nature, augment the urgent need for mental health interventions that are accessible and scalable. The World Health Organization has called for innovative strategies that extend beyond traditional cognitive approaches. Biologically based methods are gaining recognition for their significant role in affect regulation and wellness promotion. This paper explores the potential for interventions focusing on interoceptive awareness, or noticing sensations arising from the body, to address mental health challenges, especially relevant for populations affected by trauma. The Community Resiliency Model (CRM)^®, a low-intensity, body-based intervention that cultivates interoceptive awareness, is described and compared to other well-being interventions. Available research studies, program evaluations and anecdotal reports are presented in addition to CRM’s biological and theoretical underpinnings. The neurobiology of trauma, interoception research, and the concept of neural synchrony are briefly introduced, further explaining the likely mechanism of action and an underlying rationale for the reported improvements in well-being and resilience among individuals and communities who learn CRM body awareness techniques. Given increasing global demand and limited access to conventional mental health services, CRM and the six core skills that are taught in this model offer a promising, transferable, self-care strategy. Community dissemination has the potential to expand access in underserved populations. This review concludes by suggesting future research directions, such as the exploration of biophysical outcomes, intra- and interpersonal synchrony, and evaluation of interoceptive training for emotional regulation and populations affected by trauma or violence. Full article

Intrabody communication (IBC) establishes a wireless connection between devices in a Wireless Body Area Network (WBAN) by utilizing the human body as a transmission medium. The characteristics of the IBC channel are significantly influenced by the geometric and biological features of the human body and tissues. This paper analyzes a dataset with experimental real subjects’ data on signal loss in a galvanic IBC channel, models IBC identification using the K-Nearest Neighbors (KNN) algorithm, and proposes a novel IBC WBAN architecture incorporating an identification function. The analysis of the dataset revealed that the IBC channel gain exhibits a wide range of variations depending on individual human body characteristics such as height, weight, body mass index, and body composition. Consequently, biometric identification can be leveraged within the IBC WBAN paradigm. Through modeling IBC identification on cleaned and labeled data, we demonstrated an identification accuracy of 99.9% based on the results of our modeling. The proposed IBC WBAN architecture with an integrated identification function is anticipated to enhance the application scope and accelerate the development of IBC WBANs. Full article

Schizophyllum commune, a Basidiomycota fungus with a tetrapolar mating system, serves as a key model for studying sexual reproduction. In this study, two distinct mating subtypes (I and II) were identified in strain 20R-7-ZF01, isolated from subseafloor sediment, which exhibited eight different mating interaction phenotypes. Intra-subtypes exhibited colony-symmetric tetrapolar interactions (G1), whereas inter-subtype crosses yielded colony-asymmetric phenotypes (G2) and a reduced number of fruiting bodies. Nuclear migration analysis revealed that both subtypes follow the same sexual reproductive process, suggesting functional similarities despite the different reproductive outcomes. Gene silencing of mating-type loci identified the genes bbp2-9 and bbp2-7 within the B locus as key factors in determining mating subtype identity. Additionally, a similar pattern of mating subtype differentiation was observed in five other S. commune strains from both subseafloor and terrestrial environments. These findings highlight the genetic diversity within S. commune, challenge the classical understanding of fungal mating systems, and provide new insights into the genetic evolutionary mechanisms governing fungi with tetrapolar mating systems. Full article

Introduction: The most frequent local complication of insulin injection is the occurrence of subcutaneous nodules due to incorrect injection technique. Injection into nodules negatively impacts metabolic compensation and the requirement for greater insulin doses due to its partial and erratic absorption. Despite these concepts being accepted by the scientific community, it is not yet clear whether injection into nodules is causally related to worsening chronic diabetes (DM) complications and the morphological nature of such nodules. Aim: This multicenter study aimed to evaluate the associations between structural characteristics of skin nodules and chronic DM complications. A secondary endpoint was to evaluate the histological structure of those nodules, looking for differences between lipohypertrophies (LH) and amyloid nodules (LIDA). Methods: For this purpose, 816 DM patients with LH and 1033 without LH underwent a clinical and ultrasound study comparing metabolic data, injection habits, and frequency of complications. Excisional biopsies of the skin nodules were performed in a small series of eight subjects. Results: Data observed confirm a strong relationship between LH and diabetes chronic complications other than poor glycemic control. Histology of biopsies from the skin nodules showed mild foreign-body-like inflammation, prevailing mega-adipocytes (65%), apoptosis, and fibrosis but could not detect any amyloid fibrils. In four cases, intra-nodular fluid was present with an insulin concentration several times higher than in blood. Conclusions: We confirmed LHs to be significantly associated with insulin administration errors, duration of insulin therapy, greater daily doses and duration of insulin administration, and the presence of micro- and macro-vascular DM complications. LH nodules displayed no typical morphological features and were indistinguishable from LIDA nodules with which they shared several histologic similarities, albeit within the frame of a general picture of LIDA inhomogeneity. Further targeted studies are warranted to clarify the remaining doubts. Full article

Sunlight and the heat it provides are important ecological resources for reptiles especially for those species living in temperate zones that bask extensively to maximize heat uptake. Sun basking has both benefits and costs for reptiles, giving heat that provides the energy to drive physiology but basking in open patches increases risk of predation due to higher visibility. Prime basking sites are believed to increase benefits for reptiles that include, in addition to open sunlit areas, facilitate detection of predators and prey and escape to nearby refuges. However, if such sites are limited, both inter and intra-specific interference may occur and this kind of competition may impact on a reptile’s ability to access prime basking sites, and as a consequence, its capacity to thermoregulate to optimum body temperatures. This may be especially important for juveniles, for whom rapid growth is a key factor in survivorship. We studied communal basking and interaction events at prime basking sites in the European green lizard, Lacerta bilineata, in a hedgerow in western France. We compared basking behaviour of adults and juveniles with sympatric adult wall lizards Podarcis muralis using non-invasive photographic-mark-recapture. Adult L. bilineata were more evenly distributed across basking sights compared to juveniles but significant differences were only detected between males and juveniles. Juvenile L. bilineata abandoned basking sites at the approach of both adult males and females and were aggressively removed by adult male L. bilineata. We found inter-specific communal basking between both adult and juvenile L. bilineata with adult wall lizards P. muralis. Communal basking was observed between male and female L. bilineata but not between adult males or between adult female L. bilineata. Communal basking was in proportionally greater frequency in juveniles compared to adult L. bilineata. Full article

Urinary bladder diverticula are formed by the herniation of the mucosa into the muscle layer of the bladder wall, often ending with a narrow neck that communicates with the bladder lumen. They may be congenital or acquired, and they most often affect males. Urinary bladder diverticula discovery during autopsy incidence described in the literature is approximately 5–10%. Various causative factors have been described, including urinary tract obstruction (e.g., benign prostate hyperplasia) and neurogenic and iatrogenic causes. The most described site of occurrence is adjacent to the ureteral orifice. Their clinical presentation does not often facilitate diagnosis, as most are small and asymptomatic. Complications of urinary bladder diverticulosis include infections, lithiasis, neoplasia, pressure on adjacent tissues, obstruction, and rupture. Indeed, urinary bladder diverticula may lead to spontaneous bladder rupture in extremely rare cases. This paper presents the case of an 87-year-old female suffering from atrial fibrillation and under anticoagulant therapy who was pronounced dead in a hospital and was subsequently referred to our department for medico-legal examination. Upon macroscopic examination of the body, intra-abdominal hemorrhage was observed in the vicinity of the urinary bladder, extraperitoneally. A meticulous examination excluded the possibility of injury as the cause of this finding, and tissue samples were collected for histopathological examination. A ruptured urinary diverticulum was discovered and confirmed histopathologically. Death was attributed to intra-abdominal hemorrhage after rupture of urinary bladder diverticulum. A forensic pathologist should be aware of this diagnosis, as although extremely rare, such pathology may lead to death, especially when the patient is under anticoagulant therapy. Full article

Objectives: Gait speed indicates the individual’s functional status and predicts overall health. This study aims to determine (1) the intra- and inter-rater and test–retest reliability of the dynamic 4 m gait speed test protocol; (2) establish the normative reference values of habitual and fast gait speeds in community-dwelling healthy Singaporean adults aged 21 to 80; and (3) explore the association of age, gender, height, weight, and body mass index (BMI) on gait speed. Methods: This prospective cross-sectional study recruited healthy ambulatory community-dwelling Singaporeans aged 21 to 80 who could ambulate independently without aid. Participants were excluded if they required walking aids; were pregnant; or had physical, medical, or cognitive conditions that may affect gait. Each participant completed at least two habitual and fast gait speed test trials via a 4 m walkway with a dynamic start. The data were analysed by descriptive statistics, the Mann–Whitney test, the Spearman coefficient, and the interclass correlation coefficient (ICC). Results: In total, 178 males and 201 females were included in the data analysis. The median age was 45.0 years [interquartile range (IQR) 26.2–59.0], and the median height was 1.64 metres (m) (IQR 1.58–1.70). The median habitual gait speed was 1.08 metre/second (m/s) (IQR 0.97–1.22), and the fast gait speed was 1.55 m/s (IQR 1.40–1.70). The ICC for reliability ranged from 0.84 to 0.99, indicating that the 4 m gait speed test had good-to-excellent reliability. Conclusions: Gait speeds were not influenced by gender but declined with age advancement. Age and height and age and BMI were weakly correlated to habitual and fast gait speed, respectively. We established the norm values for the 4 m gait speeds in Singapore and proved it to be a reliable gait speed assessment ready for immediate community applications. Full article

Signal propagation models play a fundamental role in radio frequency communication research. However, emerging communication methods, such as body-coupled communication (BCC), require the creation of new models. In this paper, we introduce mathematical models that approximate the human body as an electrical circuit, as well as linear regression- and random forest-based predictive models that infer the expected signal loss from its frequency, measurement point locations, and body parameters. The results demonstrate a close correspondence between the amplitude-frequency response (AFR) predicted by the electrical circuit models and the experimental data gathered from volunteers. The accuracy of our predictive models was assessed by using their root mean square errors (RMSE), ranging from 1.5 to 7 dB depending on the signal frequency within the 0.05 to 20 MHz range. These results allow researchers and engineers to simulate and forecast the expected signal loss within BCC systems during their design phase. Full article

It is a known fact that gender-based violence is an infringement on human rights. Gender-based violence takes place all over the world in almost every place. It is experienced in homes, workplaces, communities, and in the Church as well. Today, church members, as well as pastors are wounded, fragmented, and hurting as they suffer serious abuses in silence. Christian children have fallen victim to sexual abuse that is perpetrated by their parents. Parents too, have become victims of violence; sometimes maimed by children who have become violent enough to kill their Christian parents in their homes. Furthermore, many Christian couples have continued to experience intra gender violence in their families that is often attributed to marital infidelity. Beyond that, there is also a common secretive kind of abuse in the form of marital sexual violence which is a serious form of violence against women. This is a hidden type of abuse that has been perpetrated behind closed doors for too long by members of the body of Christ. Due to its prevalence sometimes the victims themselves, often pretend that the problem in not present by keeping a deafening silence. This article, therefore, makes an in-depth investigation into the causes of the pervasive forms of gender-based violence that occur in some Zambian Christian homes, with particular emphasis on the ways in which this multifaceted phenomenon is very much hidden. This article expounds on how Christian couples have continued to suffer silently as their voices are suppressed due to fear and shame. In the conclusion of the article, it is suggested that, unless the church, in its pastoral care role, awakens from its slumber and begins to address issues of gender-based violence in the church with sincerity, honesty, and openness by admitting that indeed, the body of Christ is yearning to be healed, gender-based violence shall remain a perennial occurrence. Full article

Science and technology have been associated with modern Enlightenment, in a manner that elevated the rational mind over emotions and the body, a separation of the subjective mind from the object of observation, universal categories, objective observation, and linear causality. These assumptions, consolidated by Descartes and then Kant, have underpinned the philosophies of science, economics, policy, and political theory. They have shaped the modern world and enabled corporate freedom to exploit all ‘resources’ in the name of consumerism and global trade. Idealism has alienated subjective rationality from an idealised universal created world. In contrast, ancient indigenous ways of knowing are emerging as better exemplars of the interrelationship between individuals, communities, and organic and anorganic life forms. Celtic shapeshifters and praise poems forge an interwoven dance of geology, weather, plants, animals, and humanity with wisdom and politics. The Māori concept of whakapapa is the kin relations of everything, tied into complex claves as a taxonomy of familial ties. Animism was understood as pagan misidentification by modernity, but if the alienation set out by modern linear physics is severed, then the intra and inter-relationship of strata, atmosphere, ocean, and species are better relayed by indigenous philosophy than by outdated, colonial, modern assumptions. Celtic and Māori pantheism show us how entangled we are, and how special relationships are in place that last across generations. Full article

With the development of technology, systems gravitate towards increasing in their complexity, miniaturization, and level of automation. Amongst these systems, ultrasonic devices have adhered to this trend of advancement. Ultrasonic systems require transducers to generate and sense ultrasonic signals. These transducers heavily impact the system’s performance. Advancements in microelectromechanical systems have led to the development of micromachined ultrasonic transducers (MUTs), which are utilized in miniaturized ultrasound systems. Piezoelectric micromachined ultrasonic transducers (PMUTs) exhibit higher capacitance and lower electrical impedance, which enhances the transducer’s sensitivity by minimizing the effect of parasitic capacitance and facilitating their integration with low-voltage electronics. PMUTs utilize high-yield batch microfabrication with the use of thin piezoelectric films. The deposition of thin piezoelectric material compatible with complementary metal-oxide semiconductors (CMOS) has opened novel avenues for the development of miniaturized compact systems with the same substrate for application and control electronics. PMUTs offer a wide variety of applications, including medical imaging, fingerprint sensing, range-finding, energy harvesting, and intrabody and underwater communication links. This paper reviews the current research and recent advancements on PMUTs and their applications. This paper investigates in detail the important transduction metrics and critical design parameters for high-performance PMUTs. Piezoelectric materials and microfabrication processes utilized to manufacture PMUTs are discussed. Promising PMUT applications and outlook on future advancements are presented. Full article

Water microorganisms contribute to the key components of ecosystems in dryland waters, which are extremely important for wildlife. However, the distribution patterns of water microbes across different basal water sources are still largely unknown. This study was conducted to compare microorganisms in the water bodies of different types of water sources in the Kalamaili Mountain Ungulate Nature Reserve in China. Bioinformatic analysis revealed that the undirected microbial co-existence network consisted of 15 main modules referring to different water sources, which indicated specific molecular co-existence relationships. It was found that the most dominant phyla (namely Proteobacteria, Patescibacteria, Firmicutes, Bacteroidota, and Actinobacteriota) of the molecular ecological network shared the same structures as the microbial community, which justified the construction of the network via a random network formation. Principal coordinate analysis (PCoA) based on Bray–Curtis distances revealed that there were still considerable variations among different habitats, showing separate sample clusters. Additionally, the different topological roles of subnetworks trimmed to a uniform size indicated different co-existence patterns in the microbiome. The artificially recharged water from concrete pond substrate (ARC) subnetworks had a relatively discrete co-occurrence, while the natural water sources (NRE) and artificially recharged water from earthen pond substrate (ARE) groups were more compact with giant modules. The NRE and ARE groups were also richer in microbial composition and had a higher number of species with low abundance. Consequently, concrete substrates may contribute to dysfunction in water microbiomes. Moreover, the functional diversity of the NRE and ARE groups is due to more intra-module connections and more inter-module connections, indirectly leading to a stable function resilient to external environmental influences. In conclusion, the microecology of the NRE was more stable than that of the concrete substrate, and artificial transportation had less effect on the microbial community. Full article

The significance of indigenous knowledge under the current scenario of biodiversity imperilment is well-known since such knowledge is gained through continuous intergenerational observations of natural systems. In this study, we present a description of indigenous community fishing practices in Nagaland and investigate their relationship with the cultural and traditional aspects of the associated communities through oral interactions, questionnaires and as a participatory observer. We observed inter- and intra-community fishing in which the piscicidal plants Millettia pachycarpa and Derris elliptica (both Fabaceae) were used as fish poison. M. pachycarpa was commonly used in inter-community ‘fishing festivals’ since it is easily available, less laborious to collect and there are no reports of harm to the body in comparison to D. elliptica which causes allergy and/or dermatological effects. Indigenous community fishing is conducted to develop a sense of peaceful co-existence and prosperity within and among the neighboring communities. However, the increasing use of synthetic fish poisons has overlapped with the traditional practices of fishing, exerting pressure on the livelihoods and food security of the tribal populations while contributing to riverine ecosystem degradation. Formulation of policies banning synthetic fish poison, and judicious use of traditional piscicidal plant fishing is therefore recommended. Full article

Extracellular vesicles (EVs) have been exploited as bio-inspired drug delivery systems (DDS) in the biomedical field. EVs have more advantages than synthetic nanoparticles: they are naturally equipped to cross extra- and intra-cellular barriers. Furthermore, they can deliver functional biomolecules from one cell to another even far away in the body. These advantages, along with obtained promising in vivo results, clearly evidenced the potential of EVs in drug delivery. Nevertheless, due to the difficulties of finding a chemical approach that is coherent with EVs’ rational clinical therapeutic use, those in the drug delivery community are expecting more from EVs’ use. Therefore, this review gathered knowledge of the current chemical approaches dealing with the conjugation of EVs for drugs and radiotracers. Full article

Light-based events in insects deserve increasing attention for various reasons. Besides their roles in inter- and intra-specific visual communication, with biological, ecological and taxonomical implications, optical properties are also promising tools for the monitoring of insect pests and disease vectors. Among these is the Asian tiger mosquito, Aedes albopictus, a global arbovirus vector. Here we have focused on the autofluorescence characterization of Ae. albopictus adults using a combined imaging and spectrofluorometric approach. Imaging has evidenced that autofluorescence rises from specific body compartments, such as the head appendages, and the abdominal and leg scales. Spectrofluorometry has demonstrated that emission consists of a main band in the 410–600 nm region. The changes in the maximum peak position, between 430 nm and 500 nm, and in the spectral width, dependent on the target structure, indicate the presence, at variable degrees, of different fluorophores, likely resilin, chitin and melanins. The aim of this work has been to provide initial evidence on the so far largely unexplored autofluorescence of Ae. albopictus, to furnish new perspectives for the set-up of species- and sex-specific investigation of biological functions as well as of strategies for in-flight direct detection and surveillance of mosquito vectors. Full article