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758 Results Found

  • Article
  • Open Access
4 Citations
2,650 Views
22 Pages

Role of Increasing Body Mass Index in Gut Barrier Dysfunction, Systemic Inflammation, and Metabolic Dysregulation in Obesity

  • Fatima Maqoud,
  • Francesco Maria Calabrese,
  • Giuseppe Celano,
  • Domenica Mallardi,
  • Francesco Goscilo,
  • Benedetta D’Attoma,
  • Antonia Ignazzi,
  • Michele Linsalata,
  • Gabriele Bitetto and
  • Martina Di Chito
  • + 7 authors

28 December 2024

Aims: This study explores the link between body mass index (BMI), intestinal permeability, and associated changes in anthropometric and impedance parameters, lipid profiles, inflammatory markers, fecal metabolites, and gut microbiota taxa composition...

  • Article
  • Open Access
1,350 Views
13 Pages

Adenovirus 36 Seropositivity Is Related to Inflammation and Imbalance Between Oxidative Stress and Antioxidant Status Regardless of Body Mass Index in Mexican Population

  • Omar Arroyo-Xochihua,
  • Cristian Arbez-Evangelista,
  • Edgar Miranda-Contreras,
  • Yeimy Mar De León-Ramírez,
  • Montserrat Díaz-Edgar,
  • Clara Luz Sampieri,
  • Omar Arroyo-Helguera and
  • María Teresa Álvarez-Bañuelos

Background: The etiology of obesity has been associated with genetic and epigenetic factors, hormonal changes, unhealthy lifestyle habits, and infectious agents such as human adenovirus-36 (HAdV-36). Viral infections induce reactive oxygen species, a...

  • Article
  • Open Access
1,688 Views
11 Pages

2 October 2024

Background: The advanced lung cancer inflammation index (ALI) is an innovative and thorough measure designed to assess both inflammation and nutritional status. It includes parameters such as albumin, body mass index (BMI), and the neutrophil-to-lymp...

  • Feature Paper
  • Article
  • Open Access
3 Citations
2,859 Views
9 Pages

2 February 2021

Background: The serum suPAR level is affected in humans by it increases with age. Therefore it makes difficult interpretation and any comparison of age varied groups. The aim of this study is to find simple way to age independent presentation of suPA...

  • Article
  • Open Access
4 Citations
2,477 Views
13 Pages

Mediterranean Diet and Airway Inflammation in School-Aged Children

  • Mónica Rodrigues,
  • Francisca de Castro Mendes,
  • Patrícia Padrão,
  • Luís Delgado,
  • Inês Paciência,
  • Renata Barros,
  • João Cavaleiro Rufo,
  • Diana Silva,
  • André Moreira and
  • Pedro Moreira

29 July 2023

There seems to exist an intricate relationship between airway inflammation, body mass index (BMI), and diet. The intake of specific foods or food groups has been suggested to suppress the oxidative stress and inflammatory processes that characterize...

  • Feature Paper
  • Article
  • Open Access
1 Citations
3,584 Views
9 Pages

Tumor Inflammation, Obesity, and Proliferative Status as Biomarkers in Gastroesophageal Adenocarcinoma

  • Sarbajit Mukherjee,
  • R. J. Seager,
  • Yong Hee Lee,
  • Jeffrey M. Conroy,
  • Pawel Kalinski and
  • Sarabjot Pabla

7 December 2021

Recent epidemiological studies have shown that obesity, typically measured by increased body mass index (BMI), is associated with an increased risk of gastroesophageal adenocarcinoma (GEAC), but the contributing molecular and immune mechanisms remain...

  • Article
  • Open Access
1 Citations
1,472 Views
15 Pages

Obesity and Systemic Inflammation Disrupt the Compensatory Role of Physical Activity in Chronic Pain Conditions

  • Taynah Galassi,
  • Kevin Pacheco-Barrios,
  • Anna C. Gianlorenco and
  • Felipe Fregni

Objectives: This study examines the influence of body mass index (BMI) and systemic inflammation on the relationship between physical activity and chronic pain conditions. Methods: We used data from the National Health and Nutrition Examination Surve...

  • Article
  • Open Access
3 Citations
2,788 Views
15 Pages

Evaluation of Circulating Chitotriosidase Activity in Children with Obesity

  • Ioana Țaranu,
  • Mihaela Iancu,
  • Cecilia Lazea,
  • Camelia Alkhzouz,
  • Nicoleta Răcătăianu,
  • Cristina-Sorina Cătană,
  • Andreea-Manuela Mirea,
  • Diana Miclea,
  • Sorana D. Bolboacă and
  • Cristina Drugan

23 June 2022

Childhood obesity progresses to metabolic disturbances via low-grade inflammation. Identifying novel molecules that reflect the activity of the immune responses is critical in understanding its underlying pathogenesis. Our exploratory study aimed to...

  • Article
  • Open Access
1,613 Views
15 Pages

Nomogram-Based Prediction of Survival in Stage IV Nasopharyngeal Carcinoma: A Retrospective Single-Center Study

  • Peng Yeh,
  • Chih-Ming Chang,
  • Li-Jen Liao,
  • Chia-Yun Wu,
  • Chen-Hsi Hsieh,
  • Pei-Wei Shueng,
  • Po-Wen Cheng and
  • Wu-Chia Lo

Background/Objectives: To assess the pretreatment and posttreatment clinical factors associated with the rate of survival at 1, 3, and 5 years in stage IV nasopharyngeal carcinoma (NPC) patients. Methods: Clinicopathological characteristics of 61 Sta...

  • Article
  • Open Access
3 Citations
2,101 Views
10 Pages

3 March 2021

Soluble urokinase-type plasminogen activator receptor (suPAR) is a marker of immune activation and reflects a more distinct aspect of inflammation than C-reactive protein (CRP) does. The study concerns a clinically silent state of the immune system e...

  • Article
  • Open Access
4 Citations
2,092 Views
16 Pages

A Nonlinear Relation between Body Mass Index and Long-Term Poststroke Functional Outcome—The Importance of Insulin Resistance, Inflammation, and Insulin-like Growth Factor-Binding Protein-1

  • Gustaf Gadd,
  • Daniel Åberg,
  • Alexander Wall,
  • Henrik Zetterberg,
  • Kaj Blennow,
  • Katarina Jood,
  • Christina Jern,
  • Jörgen Isgaard,
  • Johan Svensson and
  • N. David Åberg

Both high serum insulin-like growth factor-binding protein-1 (s-IGFBP-1) and insulin resistance (IR) are associated with poor functional outcome poststroke, whereas overweight body mass index (BMI; 25–30) is related to fewer deaths and favorabl...

  • Article
  • Open Access
599 Views
20 Pages

Anti-Inflammatory and Antinociceptive Potential of Hydroethanolic Extract of Bauhinia guianensis Aubl. in Zebrafish (Danio rerio)

  • Rosemary de Carvalho Rocha Koga,
  • Agerdânio Andrade de Souza,
  • Priscila Faimann Sales,
  • Adriana Maciel Ferreira,
  • Gisele Custódio de Souza and
  • José Carlos Tavares Carvalho

The leaves and stems of Bauhinia guianensis Aubl. are used in traditional Amazonian phytotherapy for the treatment of pain and inflammation. This study investigates the anti-inflammatory and antinociceptive effects of hydroethanolic extracts from B....

  • Article
  • Open Access
4 Citations
4,904 Views
11 Pages

Association of Dietary Inflammatory Index and Thyroid Function in Patients with Hashimoto’s Thyroiditis: An Observational Cross–Sectional Multicenter Study

  • Sanja Klobučar,
  • Gordana Kenđel Jovanović,
  • Jadwiga Kryczyk-Kozioł,
  • Maja Cigrovski Berković,
  • Jelena Vučak Lončar,
  • Nikolina Morić,
  • Katarina Peljhan,
  • Dario Rahelić,
  • Dunja Mudri and
  • Ines Bilić-Ćurčić
  • + 1 author

5 September 2024

Background and Objectives: The available research suggests that dietary patterns with high inflammatory potential, as indicated by a high DII score, may exacerbate inflammation and potentially influence thyroid function. Therefore, the aim of this st...

  • Review
  • Open Access
12 Citations
3,745 Views
25 Pages

Inflammatory Pathways in Overweight and Obese Persons as a Potential Mechanism for Cognitive Impairment and Earlier Onset Alzeihmer’s Dementia in the General Population: A Narrative Review

  • Alexandru Dan Costache,
  • Bogdan Emilian Ignat,
  • Cristina Grosu,
  • Alexandra Mastaleru,
  • Irina Abdulan,
  • Andra Oancea,
  • Mihai Roca,
  • Maria Magdalena Leon,
  • Minerva Codruta Badescu and
  • Stefana Luca
  • + 5 authors

The overweight status or obesity can be confirmed through classical methods such as the body mass index (BMI) and the waist-to-hip ratio (WHR). Apart from metabolic issues such as atherosclerosis, liver steatosis, or diabetes mellitus, long-term obes...

  • Article
  • Open Access
3 Citations
2,092 Views
8 Pages

16 September 2022

Background: Fractional exhaled nitric oxide (FeNO) is recognized as a biomarker of eosinophilic inflammation. Current literature shows evidence that FeNO is influenced by many factors. Obesity is a chronic inflammatory state. In this study, we consid...

  • Article
  • Open Access
1 Citations
1,168 Views
13 Pages

Amyotrophic lateral sclerosis (ALS) is a heterogeneous disease that involves progressive loss of voluntary muscle and ultimately, respiratory function, which is the primary cause of death in ALS patients. Respiratory vital capacity (VC) measurements...

  • Article
  • Open Access
1,207 Views
20 Pages

Exploring Socio-Behavioral Correlates of Metabolic and Inflammatory Risk in a University Sample Residing Along the U.S./Mexico Border: A Pilot Study Concomitantly Collecting Survey Data, Blood and Hair Samples, and Physical Measures

  • Gabriel A. Frietze,
  • Cai Xu,
  • Bibiana Mancera,
  • Elisa Robles-Escajeda,
  • Alyssa A. Martinez,
  • Michelle Gil,
  • Diana P. Flores,
  • Khodeza Begum,
  • Panfeng Liang and
  • Abhijit Mandal
  • + 5 authors

Hispanic adults have an increased incidence of type 2 diabetes (T2D) at a younger age and diagnosis of certain cancers, including liver, stomach, and colorectal, which may be attributed to metabolic health. Several key metabolic health indicators, su...

  • Article
  • Open Access
12 Citations
3,291 Views
16 Pages

Relationships of Body Mass Index, Relative Fat Mass Index, and Waist Circumference with Serum Concentrations of Parameters of Chronic Inflammation

  • Magdalena Sylwia Kamińska,
  • Anna Lubkowska,
  • Mariusz Panczyk,
  • Ireneusz Walaszek,
  • Szymon Grochans,
  • Elżbieta Grochans and
  • Anna Maria Cybulska

18 June 2023

(1) Background: Obesity in the perimenopausal period is associated with hormonal changes, lifestyle, and environment. In obesity, elevated levels of IL-6 and TNF-α and reduced levels of adiponectin are observed, and the associated chronic infla...

  • Article
  • Open Access
21 Citations
5,004 Views
14 Pages

Anemia Is a Strong Predictor of Wasting, Disease Severity, and Progression, in Clinical Tuberculosis (TB)

  • Senait Ashenafi,
  • Amsalu Bekele,
  • Getachew Aseffa,
  • Wondwossen Amogne,
  • Endale Kassa,
  • Getachew Aderaye,
  • Alemayehu Worku,
  • Peter Bergman and
  • Susanna Brighenti

12 August 2022

A typical trait of chronic tuberculosis (TB) is substantial weight loss that concurs with a drop in blood hemoglobin (Hb) levels, causing anemia. In this observational study, we explored Hb levels in 345 pulmonary TB patients. They were divided into...

  • Article
  • Open Access
4 Citations
2,842 Views
11 Pages

5 July 2023

Vitamin D deficiency (VDD) is increasingly prevalent on a global scale and is connected to chronic health issues including diabetes, obesity, and inflammation. This study aimed to investigate the association between VDD and various clinical parameter...

  • Article
  • Open Access
2 Citations
1,606 Views
17 Pages

Autoimmune Processes and Chronic Inflammation as Independent Risk Factors for Metabolic Complications in Women with Polycystic Ovary Syndrome

  • Katarzyna Suchta,
  • Natalia Zeber-Lubecka,
  • Monika Grymowicz,
  • Roman Smolarczyk,
  • Maria Kulecka and
  • Ewa E. Hennig

20 February 2025

Background: Polycystic ovary syndrome (PCOS) and autoimmune thyroid disease (AITD) have a high prevalence in women of reproductive age. PCOS can lead to long-term adverse health effects such as obesity, diabetes, and increased metabolic and cardiovas...

  • Review
  • Open Access
89 Citations
16,360 Views
29 Pages

Effect of Probiotic Bacteria on Microbial Host Defense, Growth, and Immune Function in Human Immunodeficiency Virus Type-1 Infection

  • Susanna Cunningham-Rundles,
  • Siv Ahrné,
  • Rosemary Johann-Liang,
  • Rachel Abuav,
  • Ann-Margaret Dunn-Navarra,
  • Claudia Grassey,
  • Stig Bengmark and
  • Joseph S. Cervia

19 December 2011

The hypothesis that probiotic administration protects the gut surface and could delay progression of Human Immunodeficiency Virus type1 (HIV-1) infection to the Acquired Immunodeficiency Syndrome (AIDS) was proposed in 1995. Over the last five years,...

  • Article
  • Open Access
69 Citations
6,886 Views
9 Pages

Factors Associated with Decreased Lean Tissue Index in Patients with Chronic Kidney Disease

  • Yi-Wen Wang,
  • Ting-Yun Lin,
  • Ching-Hsiu Peng,
  • Jui-Lin Huang and
  • Szu-Chun Hung

27 April 2017

Muscle wasting is common and is associated with increased morbidity and mortality in patients with chronic kidney disease (CKD). However, factors associated with decreased muscle mass in CKD patients are seldom reported. We performed a cross-sectiona...

  • Review
  • Open Access
74 Citations
10,690 Views
22 Pages

Exploring the Links between Obesity and Psoriasis: A Comprehensive Review

  • Gabriela Barros,
  • Pablo Duran,
  • Ivana Vera and
  • Valmore Bermúdez

Obesity is a major public health issue worldwide since it is associated with the development of chronic comorbidities such as type 2 diabetes, dyslipidemias, atherosclerosis, some cancer forms and skin diseases, including psoriasis. Scientific eviden...

  • Article
  • Open Access
8 Citations
2,707 Views
11 Pages

Comparison of Pulmonary Function and Inflammation in Children/Adolescents with New-Onset Asthma with Different Adiposity Statuses

  • Xiaolan Ying,
  • Jie Lin,
  • Shuhua Yuan,
  • Chunhong Pan,
  • Wenfang Dong,
  • Jing Zhang,
  • Lei Zhang,
  • Jilei Lin,
  • Yong Yin and
  • Jinhong Wu

20 July 2022

(1) Background: The relationship between obesity and asthma is still uncertain. This study aimed to investigate the effect of overweight/obesity on the pulmonary function of patients with new-onset pediatric asthma and explore the possible causative...

  • Article
  • Open Access
11 Citations
3,402 Views
10 Pages

Phytic acid has anti-oxidant properties, which are useful in addressing inflammation. This study investigated the relationship between dietary phytate intake and C-reactive protein (CRP) levels among individuals that are overweight or obese. The stud...

  • Article
  • Open Access
23 Citations
5,686 Views
14 Pages

The Effects of Aerobic-Resistance Training and Broccoli Supplementation on Plasma Dectin-1 and Insulin Resistance in Males with Type 2 Diabetes

  • Ayoub Saeidi,
  • Mohammad Soltani,
  • Ali Daraei,
  • Hanieh Nohbaradar,
  • Marjan Mosalman Haghighi,
  • Nikoo Khosravi,
  • Kelly E. Johnson,
  • Ismail Laher,
  • Anthony C. Hackney and
  • Trisha A. VanDusseldorp
  • + 1 author

9 September 2021

Background: This study aimed to evaluate the effects of a combination of aerobic-resistance training (CARET) and broccoli supplementation on dectin-1 levels and insulin resistance in men with type 2 diabetes mellitus (T2D). Methods: Forty-four males...

  • Article
  • Open Access
24 Citations
3,230 Views
16 Pages

Correlation of Leptin, Proinflammatory Cytokines and Oxidative Stress with Tumor Size and Disease Stage of Endometrioid (Type I) Endometrial Cancer and Review of the Underlying Mechanisms

  • Clelia Madeddu,
  • Elisabetta Sanna,
  • Giulia Gramignano,
  • Luciana Tanca,
  • Maria Cristina Cherchi,
  • Brunella Mola,
  • Marco Petrillo and
  • Antonio Macciò

6 January 2022

Endometrioid endometrial cancer is associated with increased BMI and obesity through multiple pathogenetic mechanisms involving hyperestrogenism, hyperinsulinemia, altered adipokine secretion, inflammation, and oxidative stress. In the present study,...

  • Article
  • Open Access
16 Citations
12,622 Views
18 Pages

Body Mass Index and Total Symptom Burden in Myeloproliferative Neoplasms Discovery of a U-shaped Association

  • Sarah Friis Christensen,
  • Robyn Marie Scherber,
  • Nana Brochmann,
  • Martin Goros,
  • Jonathan Gelfond,
  • Christen Lykkegaard Andersen,
  • Esben Meulengracht Flachs and
  • Ruben Mesa

6 August 2020

Elevated body mass index (BMI) is a global health problem, leading to enhanced mortality and the increased risk of several cancers including essential thrombocythemia (ET), a subtype of the Philadelphia-chromosome negative myeloproliferative neoplasm...

  • Article
  • Open Access
12 Citations
3,797 Views
15 Pages

3 September 2022

Nutritional status is a predictor of adverse outcomes and mortality in patients with advanced chronic kidney disease (ACKD). This study aimed to explore and evaluate risk factors related to nutritional status, body composition, and inflammatory profi...

  • Review
  • Open Access
1 Citations
1,029 Views
17 Pages

Management Strategies for Dry Eye Syndrome in Patients with Obesity—A Literature Review

  • Cosmin Victor Ganea,
  • Călina Anda Sandu,
  • Corina Georgiana Bogdănici and
  • Camelia Margareta Bogdănici

14 July 2025

Tear film alterations are commonly associated with ocular pathology. The tear film plays a vital role in maintaining the optical properties of the cornea and contains essential elements required for healing and preserving the integrity of the ocular...

  • Article
  • Open Access
1 Citations
4,998 Views
25 Pages

Diseases, including cardiovascular disease, type II diabetes, and metabolic syndrome, are leading causes of morbidity and mortality worldwide. Non-alcoholic fatty liver disease (NAFLD) is commonly associated with these conditions through shared patho...

  • Article
  • Open Access
1 Citations
1,401 Views
12 Pages

Pilot Data Suggest That Obesity and Presence of Malignancy Are Associated with Altered Immune Cell Infiltration in Endometrial Biopsies

  • Eline Jacques,
  • Anouk van den Bosch,
  • Peggy de Vos van Steenwijk,
  • Loes Kooreman,
  • Bert Delvoux,
  • Andrea Romano and
  • Henrica Werner

28 November 2024

(1) Background: The worldwide endometrial cancer (EC) incidence is rising, amongst others linked to obesity, type 2 diabetes mellitus (T2DM), and metabolic syndrome, possibly due to low-grade adipose tissue inflammation. We studied immune cell infilt...

  • Article
  • Open Access
17 Citations
8,251 Views
15 Pages

The Role of Lactobacillus plantarum in Reducing Obesity and Inflammation: A Meta-Analysis

  • Chen-Pi Li,
  • Chin-Chang Chen,
  • Yao Hsiao,
  • Chieh-Hsin Kao,
  • Chin-Chu Chen,
  • Hao-Jan Yang and
  • Ru-Yin Tsai

Recent research has underscored the efficacy of Lactobacillus plantarum (L. plantarum) in managing obesity among healthy adults. This meta-analysis reviewed randomized controlled trials (RCTs) from major databases up to May 2024, focusing on the effe...

  • Systematic Review
  • Open Access
1 Citations
3,587 Views
24 Pages

Background/Objectives: This systematic review and meta-analysis aimed to investigate the effect of prebiotics, alone or as part of synbiotics, on cardiometabolic parameters in polycystic ovary syndrome (PCOS) women. Methods: Databases, including PubM...

  • Article
  • Open Access
1,095 Views
23 Pages

Maternal BMI and Diet Quality Modulate Pregnancy Oxidative and Inflammatory Homeostasis

  • Chiara Mandò,
  • Chiara Novielli,
  • Anna Maria Nuzzo,
  • Francesca Parisi,
  • Laura Moretti,
  • Fabrizia Lisso,
  • Alberto Revelli,
  • Valeria M. Savasi,
  • Arianna Laoreti and
  • Gaia M. Anelli
  • + 2 authors

9 August 2025

Background/Objectives: Maternal nutrition and pregestational BMI are critical determinants of pregnancy outcomes. This prospective multicenter observational study investigated the interplay between prepregnancy BMI, dietary patterns, and oxidative/in...

  • Article
  • Open Access
1,907 Views
22 Pages

28 August 2025

Metabolic syndrome refers to a group of conditions that commonly occur together, including abdominal obesity, high blood pressure, elevated blood sugar, high triglyceride levels, and low high-density lipoprotein cholesterol (HDL). These factors colle...

  • Article
  • Open Access
3 Citations
2,866 Views
10 Pages

Does the Severity of Obstructive Sleep Apnea Have an Independent Impact on Systemic Inflammation?

  • Romana Suša,
  • Vojislav Ćupurdija,
  • Ljiljana Novković,
  • Miloš Ratinac,
  • Slobodan Janković,
  • Danijela Đoković,
  • Jovan Jovanović,
  • Katarina Pantić,
  • Stefan Simović and
  • Danijela Bazić-Sretenović
  • + 1 author

22 March 2021

Background and Objectives: This paper aims to show whether obstructive sleep apnea (OSA) severity increases the level of systemic inflammation markers regardless of body mass index (BMI) and body composition. Materials and Methods: In total, 128 pati...

  • Article
  • Open Access
9 Citations
4,546 Views
11 Pages

22 December 2018

Osteoarthritis (OA) is a leading cause of immobility in the United States and is associated with older age, inflammation, and obesity. Prudent dietary patterns have been associated with disease prevention, yet little evidence exists describing diet q...

  • Article
  • Open Access
4 Citations
3,365 Views
10 Pages

24 July 2024

Background and Objectives: This study investigated the impact of nutritional status and foods consumed on inflammation and disease activity in patients with rheumatoid arthritis (RA). Materials and Methods: We designed a cross-sectional observational...

  • Article
  • Open Access
7 Citations
2,538 Views
14 Pages

Associations of Blood and Performance Parameters with Signs of Periodontal Inflammation in Young Elite Athletes—An Explorative Study

  • Cordula Leonie Merle,
  • Lisa Richter,
  • Nadia Challakh,
  • Rainer Haak,
  • Gerhard Schmalz,
  • Ian Needleman,
  • Peter Rüdrich,
  • Bernd Wolfarth,
  • Dirk Ziebolz and
  • Jan Wüstenfeld

31 August 2022

This retrospective cross-sectional study aimed to explore interactions between signs of periodontal inflammation and systemic parameters in athletes. Members of German squads with available data on sports medical and oral examination were included. G...

  • Article
  • Open Access
10 Citations
4,893 Views
15 Pages

Short- and Long-Term Effectiveness of Supplementation with Non-Animal Chondroitin Sulphate on Inflammation, Oxidative Stress and Functional Status in Obese Subjects with Moderate Knee Osteoarthritis before and after Physical Stress: A Randomized, Double-Blind, Placebo-Controlled Trial

  • Mariangela Rondanelli,
  • Niccolò Miraglia,
  • Pietro Putignano,
  • Gabriella Peroni,
  • Milena Anna Faliva,
  • Maurizio Naso,
  • Clara Gasparri,
  • Vittoria Infantino,
  • Mara Nichetti and
  • Nicola Volpi
  • + 3 authors

7 December 2020

It has recently been demonstrated that chronic supplementation with nonanimal chondroitin sulfate (nonanimal CS) in overweight subjects with knee osteoarthritis (OA) improves the function, pain and inflammation, but there are no studies of its effect...

  • Article
  • Open Access
47 Citations
8,996 Views
11 Pages

Dietary Inflammatory Index Score and Its Association with Body Weight, Blood Pressure, Lipid Profile, and Leptin in Indonesian Adults

  • Harry Freitag Luglio Muhammad,
  • Marleen A. van Baak,
  • Edwin C. Mariman,
  • Dian Caturini Sulistyoningrum,
  • Emy Huriyati,
  • Yi Yi Lee and
  • Wan Abdul Manan Wan Muda

11 January 2019

It was previously reported that dietary intake is an important trigger for systemic inflammation and one of the lifestyle factors for the development of cardiovascular diseases. The aim of this study was to evaluate the association between Dietary In...

  • Article
  • Open Access
93 Citations
5,223 Views
11 Pages

The Aggregate Index of Systemic Inflammation (AISI): A Novel Prognostic Biomarker in Idiopathic Pulmonary Fibrosis

  • Angelo Zinellu,
  • Claudia Collu,
  • Mouhamad Nasser,
  • Panagiotis Paliogiannis,
  • Sabrina Mellino,
  • Elisabetta Zinellu,
  • Julie Traclet,
  • Kais Ahmad,
  • Arduino Aleksander Mangoni and
  • Ciriaco Carru
  • + 3 authors

14 September 2021

Variable patterns of disease progression are typically observed in patients with idiopathic pulmonary fibrosis (IPF). We sought to determine the prognostic capacity of blood cell count indexes, derived from routine complete blood cell (CBC) count, in...

  • Review
  • Open Access
70 Citations
6,275 Views
12 Pages

4 September 2019

Background and aim: Cancer is the second leading cause of death globally. Nutritional status (cachexia) and systemic inflammation play a significant role in predicting cancer outcome. The aim of the present review was to examine the relationship betw...

  • Article
  • Open Access
8 Citations
1,001 Views
6 Pages

Correlation between Hyperinflation Defined as an Elevated RV/TLC Ratio and Body Composition and Cytokine Profile in Patients with Chronic Obstructive Pulmonary Disease

  • Renata Rubinsztajn,
  • Tadeusz Przybyłowski,
  • Marta Maskey-Warzęchowska,
  • Magdalena Paplińska-Goryca,
  • Krzysztof Karwat,
  • Patrycja Nejman-Gryz and
  • Ryszarda Chazan

10 March 2015

Introduction: Body composition is an important prognostic factor in patients with COPD. The decrease in fat free mass (FFM), muscle mass (MM) and increase in visceral fat is associated with an elevated secretion of cytokines which promote systemic in...

  • Article
  • Open Access
12 Citations
3,669 Views
17 Pages

Nutritional Risk and Sarcopenia Features in Patients with Crohn’s Disease: Relation to Body Composition, Physical Performance, Nutritional Questionnaires and Biomarkers

  • Konstantinos Papadimitriou,
  • Paraskevi Detopoulou,
  • Konstantinos Soufleris,
  • Gavriela Voulgaridou,
  • Despoina Tsoumana,
  • Panagiotis Ntopromireskou,
  • Constantinos Giaginis,
  • Ioanna P. Chatziprodromidou,
  • Maria Spanoudaki and
  • Sousana K. Papadopoulou

17 August 2023

Patients with Crohn’s disease (CD) face malnutrition risk, which, combined with inflammation, can lead to sarcopenia, associated with a worse prognosis. The purpose of the present study was to assess malnutrition and sarcopenia in patients with...

  • Article
  • Open Access
2 Citations
3,626 Views
13 Pages

The Planetary Health Diet and Its Association with Asthma and Airway Inflammation in School-Aged Children

  • Mónica Rodrigues,
  • Patrícia Padrão,
  • Francisca de Castro Mendes,
  • André Moreira and
  • Pedro Moreira

12 July 2024

Poor dietary choices have been rising concurrently with an increase in asthma prevalence, especially in children. Dietary indexes that simultaneously measure the healthiness and sustainability of dietary patterns have emerged to address the dual conc...

  • Article
  • Open Access
18 Citations
6,129 Views
10 Pages

The Effect of Dietary Glycemic Properties on Markers of Inflammation, Insulin Resistance, and Body Composition in Postmenopausal American Women: An Ancillary Study from a Multicenter Protein Supplementation Trial

  • Violeta Stojkovic,
  • Christine A. Simpson,
  • Rebecca R. Sullivan,
  • Anna Maria Cusano,
  • Jane E. Kerstetter,
  • Anne M. Kenny,
  • Karl L. Insogna and
  • Jessica D. Bihuniak

11 May 2017

Controversy exists as to whether high glycemic index/glycemic load (GI/GL) diets increase the risk of chronic inflammation, which has been postulated as a pathogenic intermediary between such diets and age-related alterations in body composition and...

  • Feature Paper
  • Article
  • Open Access
1 Citations
1,454 Views
10 Pages

Low Serum Methylglyoxal Levels Correlate with Psoriasis Severity and Inflammatory Response Indices

  • Aleksandra Damasiewicz-Bodzek,
  • Agnieszka Nowak,
  • Maciej Maciejczyk,
  • Sławomir Waligóra and
  • Brygida Przywara-Chowaniec

Psoriasis is a multifactorial inflammatory disease. Methylglyoxal (MG) is a highly reactive dicarbonyl compound responsible for dicarbonyl stress in some inflammatory conditions, and it may play a role in the etiopathogenesis of psoriasis. Methods: A...

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