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MDPIMDPI

4 Results Found

  • Review
  • Open Access
2 Citations
2,769 Views
11 Pages
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Enhancing Pathogen Detection in Implant-Related Infections through Chemical Antibiofilm Strategies: A Comprehensive Review

  • Fabiana Giarritiello,
  • Carlo Luca Romanò,
  • Guenter Lob,
  • Joseph Benevenia,
  • Hiroyuki Tsuchiya,
  • Emanuele Zappia and
  • Lorenzo Drago
Antibiotics2024, 13(7), 678;https://doi.org/10.3390/antibiotics13070678

22 July 2024

Implant-related infections (IRIs) represent a significant challenge to modern surgery. The occurrence of these infections is due to the ability of pathogens to aggregate and form biofilms, which presents a challenge to both the diagnosis and subseque...

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  • Article
  • Open Access
4 Citations
2,990 Views
10 Pages
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Evaluating the Clinical Relevance of Routine Sonication for Periprosthetic Hip or Knee Joint Infection Diagnosis

  • Anas Zouitni,
  • Jakob van Oldenrijk,
  • P. Koen Bos,
  • Peter D. Croughs,
  • Erlangga Yusuf and
  • Ewout S. Veltman
Antibiotics2024, 13(4), 366;https://doi.org/10.3390/antibiotics13040366

17 April 2024

Periprosthetic joint infection (PJI) is a serious complication after joint arthroplasty. PJI screening and conventional cultures may be inconclusive. Sonication fluid culturing stands out as a valuable adjunct technique for PJI diagnosis. This study...

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  • Article
  • Open Access
15 Citations
3,376 Views
14 Pages
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Cu2+ Release from Polylactic Acid Coating on Titanium Reduces Bone Implant-Related Infection

  • Chengdong Zhang,
  • Xingping Li,
  • Dongqin Xiao,
  • Qiao Zhao,
  • Shuo Chen,
  • Fei Yang,
  • Jinhui Liu and
  • Ke Duan
J. Funct. Biomater.2022, 13(2), 78;https://doi.org/10.3390/jfb13020078

10 June 2022

Implant-related infection (IRI) is a major problem in orthopedics. Copper (Cu) is an essential trace element with strong bactericidal activity and, thus, presents potential for reducing IRI. The present study explored a straightforward strategy for r...

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  • Review
  • Open Access
29 Citations
3,965 Views
12 Pages
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Functionalization of Synthetic Bone Substitutes

  • André Busch,
  • Marcus Jäger,
  • Constantin Mayer and
  • Andrea Sowislok
Int. J. Mol. Sci.2021, 22(9), 4412;https://doi.org/10.3390/ijms22094412

23 April 2021

Bone substitutes have been applied to treat osseous defects for a long time. To prevent implant related infection (IRI) and enhance bone healing functionalized biomaterials, antibiotics and osteoinductive substances have been introduced. This study g...

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