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Article

3 Citations

2,737 Views

20 Pages

Computational Prediction of RNA–RNA Interactions between Small RNA Tracks from Betacoronavirus Nonstructural Protein 3 and Neurotrophin Genes during Infection of an Epithelial Lung Cancer Cell Line: Potential Role of Novel Small Regulatory RNA

Alexis Felipe Rojas-Cruz and
Clara Isabel Bermúdez-Santana

Viruses2023, 15(8), 1647;https://doi.org/10.3390/v15081647

28 July 2023

Whether RNA–RNA interactions of cytoplasmic RNA viruses, such as Betacoronavirus, might end in the biogenesis of putative virus-derived small RNAs as miRNA-like molecules has been controversial. Even more, whether RNA–RNA interactions of...

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Review

56 Citations

7,896 Views

15 Pages

Oxidative Stress and Air Pollution: Its Impact on Chronic Respiratory Diseases

Martha Patricia Sierra-Vargas,
Josaphat Miguel Montero-Vargas,
Yazmín Debray-García,
Juan Carlos Vizuet-de-Rueda,
Alejandra Loaeza-Román and
Luis M. Terán

Int. J. Mol. Sci.2023, 24(1), 853;https://doi.org/10.3390/ijms24010853

3 January 2023

Redox regulation participates in the control of various aspects of metabolism. Reactive oxygen and nitrogen species participate in many reactions under physiological conditions. When these species overcome the antioxidant defense system, a distressed...

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Article

10 Citations

3,054 Views

11 Pages

Staphylococcal Panton–Valentine Leucocidin and Gamma Haemolysin Target and Lyse Mature Bone Marrow Leucocytes

Elisabeth Hodille,
Adriana Plesa,
Eve Bourrelly,
Lucie Belmont,
Cédric Badiou,
Gerard Lina and
Oana Dumitrescu

Toxins2020, 12(11), 725;https://doi.org/10.3390/toxins12110725

20 November 2020

Staphylococcus aureus is a major human pathogen, inducing several infections ranging from the benign to the life-threatening, such as necrotising pneumonia. S. aureus is capable of producing a great variety of virulence factors, such as bicomponent p...

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Article

16 Citations

4,106 Views

18 Pages

Unlike Chloroquine, Mefloquine Inhibits SARS-CoV-2 Infection in Physiologically Relevant Cells

Carolina Q. Sacramento,
Natalia Fintelman-Rodrigues,
Suelen S. G. Dias,
Jairo R. Temerozo,
Aline de Paula D. Da Silva,
Carine S. da Silva,
Camilla Blanco,
André C. Ferreira,
Mayara Mattos and
Vinicius C. Soares
+ 13 authors

Viruses2022, 14(2), 374;https://doi.org/10.3390/v14020374

11 February 2022

Despite the development of specific therapies against severe acute respiratory coronavirus 2 (SARS-CoV-2), the continuous investigation of the mechanism of action of clinically approved drugs could provide new information on the druggable steps of vi...

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Article

28 Citations

5,167 Views

19 Pages

Potential Role of Circulating Endoglin in Hypertension via the Upregulated Expression of BMP4

Eunate Gallardo-Vara,
Luis Gamella-Pozuelo,
Lucía Perez-Roque,
José L. Bartha,
Irene Garcia-Palmero,
J. Ignacio Casal,
José M. López-Novoa,
Miguel Pericacho and
Carmelo Bernabeu

Cells2020, 9(4), 988;https://doi.org/10.3390/cells9040988

16 April 2020

Endoglin is a membrane glycoprotein primarily expressed by the vascular endothelium and involved in cardiovascular diseases. Upon the proteolytic processing of the membrane-bound protein, a circulating form of endoglin (soluble endoglin, sEng) can be...

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