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6,277 Results Found

  • Article
  • Open Access
3 Citations
3,405 Views
14 Pages

High-Risk Regions of African Swine Fever Infection in Mozambique

  • Azido Ribeiro Mataca,
  • Francisco Alyson Silva Oliveira,
  • Ângelo André Lampeão,
  • José Pereira Mendonça,
  • Maria Aparecida Scatamburlo Moreira,
  • Rinaldo Aparecido Mota,
  • Wagnner José Nascimento Porto,
  • David Germano Gonçalves Schwarz and
  • Abelardo Silva-Júnior

20 April 2023

African swine fever (ASF) is a transboundary infectious disease that can infect wild and domestic swine and requires enhanced surveillance between countries. In Mozambique, ASF has been reported across the country, spreading between provinces, mainly...

  • Article
  • Open Access
2 Citations
2,530 Views
11 Pages

N-Acetylaspartate and Choline Metabolites in Cortical and Subcortical Regions in Clinical High Risk Relative to Healthy Control Subjects: An Exploratory 7T MRSI Study

  • Ahmad Mayeli,
  • Sabine A. Janssen,
  • Chloe A. Huston,
  • Julia S. Rupp,
  • Kamakashi Sharma,
  • Chan-Hong Moon,
  • Ahmadreza Keihani,
  • Hoby P. Hetherington and
  • Fabio Ferrarelli

N-acetylaspartate (NAA) and choline (Cho) are two brain metabolites implicated in several key neuronal functions. Abnormalities in these metabolites have been reported in both early course and chronic patients with schizophrenia (SCZ). It is, however...

  • Article
  • Open Access
2,155 Views
17 Pages

Epidemiological Trends and Age–Period–Cohort Effects on Dengue Incidence Across High-Risk Regions from 1992 to 2021

  • Yu Cao,
  • Hanwu Chen,
  • Hao Wu,
  • Bin Wu,
  • Lu Wang,
  • Xin Liu,
  • Yuyue Yang,
  • Hui Tan and
  • Wei Gao

Dengue, an acute infectious disease caused by the dengue virus, remains a major public health problem in the 21st century. This study investigated the global dengue burden, identified high-risk regions, evaluated the long-term incidence trends, and c...

  • Systematic Review
  • Open Access
4 Citations
3,242 Views
28 Pages

Molecular Epidemiology of Pseudomonas aeruginosa in Brazil: A Systematic Review and Meta-Analysis

  • Yan Corrêa Rodrigues,
  • Marcos Jessé Abrahão Silva,
  • Herald Souza dos Reis,
  • Pabllo Antonny Silva dos Santos,
  • Daniele Melo Sardinha,
  • Maria Isabel Montoril Gouveia,
  • Carolynne Silva dos Santos,
  • Davi Josué Marcon,
  • Caio Augusto Martins Aires and
  • Cintya de Oliveira Souza
  • + 4 authors

17 October 2024

Background: Globally, Pseudomonas aeruginosa is a high-priority opportunistic pathogen which displays several intrinsic and acquired antimicrobial resistance (AMR) mechanisms, leading to challenging treatments and mortality of patients. Moreover, its...

  • Article
  • Open Access
17 Citations
3,988 Views
14 Pages

About 8% of the Americans contract influenza during an average season according to the Centers for Disease Control and Prevention in the United States. It is necessary to strengthen the early warning for influenza and the prediction of public health....

  • Article
  • Open Access
12 Citations
1,998 Views
29 Pages

Design and Analysis of a New COVID-19 Model with Comparative Study of Control Strategies

  • Azhar Iqbal Kashif Butt,
  • Saira Batool,
  • Muhammad Imran and
  • Muneerah Al Nuwairan

22 April 2023

The COVID-19 pandemic has become a worldwide concern and has caused great frustration in the human community. Governments all over the world are struggling to combat the disease. In an effort to understand and address the situation, we conduct a thor...

  • Article
  • Open Access
42 Citations
8,638 Views
18 Pages

Patterns of Bacillary Dysentery in China, 2005–2010

  • Han Zhang,
  • Yali Si,
  • Xiaofeng Wang and
  • Peng Gong

Although the incidence of bacillary dysentery in China has been declining progressively, a considerable disease burden still exists. Few studies have analyzed bacillary dysentery across China and knowledge gaps still exist in the aspects of geographi...

  • Article
  • Open Access
1,421 Views
19 Pages

Climate change has magnified health disparities across the Southern African Development Community (SADC) region by destabilizing the critical natural systems, which include water security, food production, and disease ecology. The IPCC (2007) undersc...

  • Article
  • Open Access
8 Citations
2,431 Views
16 Pages

24 November 2021

The dry valley is a unique geographic phenomenon in Southwest China with severe water erosion. However, little is known regarding its dominant controls and the discrepancies between dry valley subtypes, leading to the poor management of water erosion...

  • Article
  • Open Access
1 Citations
1,630 Views
10 Pages

Impact of the COVID-19 Pandemic on the Detection of Leprosy in Micro-Regions with a High Risk of Illness in Minas Gerais, Brazil

  • Sarah Lamas Vidal,
  • Daniele dos Santos Lages,
  • Isabela Cristina Lana Maciel,
  • Isabel Cristina Gonçalves Leite,
  • Angélica da Conceição Oliveira Coelho and
  • Francisco Carlos Félix Lana

26 November 2024

Background: Leprosy control remains challenging in Brazil and has been aggravated by the COVID-19 pandemic. Objective: To analyze the impact of the COVID-19 pandemic on the epidemiological scenario of leprosy through the detection rate of new cases,...

  • Review
  • Open Access
8 Citations
6,879 Views
10 Pages

Regional Anesthesia Techniques for Shoulder Surgery in High-Risk Pulmonary Patients

  • Bradley H. Lee,
  • William P. Qiao,
  • Stephen McCracken,
  • Michael N. Singleton and
  • Mikhail Goman

16 May 2023

Patients with pre-existing pulmonary conditions are at risk for experiencing perioperative complications and increased morbidity. General anesthesia has historically been used for shoulder surgery, though regional anesthesia techniques are increasing...

  • Article
  • Open Access
3 Citations
3,947 Views
23 Pages

28 November 2024

This study evaluates the environmental impact of earthquake-resistant structural design choices in high-risk seismic regions through life cycle assessment. As climate change concerns intensify, understanding the environmental implications of structur...

  • Article
  • Open Access
14 Citations
3,294 Views
13 Pages

Intensity-Modulated Radiotherapy with Regional Hyperthermia for High-Risk Localized Prostate Carcinoma

  • Sota Nakahara,
  • Takayuki Ohguri,
  • Sho Kakinouchi,
  • Hirohide Itamura,
  • Takahiro Morisaki,
  • Subaru Tani,
  • Katuya Yahara and
  • Naohiro Fujimoto

13 January 2022

Background: The purpose of this study was to evaluate the efficacy and toxicity of adding regional hyperthermia to intensity-modulated radiotherapy (IMRT) plus neoadjuvant androgen deprivation therapy (ADT) for high-risk localized prostate carcinoma....

  • Article
  • Open Access
13 Citations
6,185 Views
22 Pages

23 January 2024

Community risk and resilience to high-latitude wildfires has received limited conceptual attention, with a comprehensive, integrated framework that unpacks the complex human–fire–climate relationship in high-latitude environments largely...

  • Article
  • Open Access
6 Citations
5,730 Views
19 Pages

Outcomes of Secondary Prevention among Coronary Heart Disease Patients in a High-Risk Region in Finland

  • Teppo Repo,
  • Markku Tykkyläinen,
  • Juha Mustonen,
  • Tuomas T. Rissanen,
  • Matti Ketonen,
  • Maija Toivakka and
  • Tiina Laatikainen

Despite comprehensive national treatment guidelines, goals for secondary prevention of coronary heart disease (CHD) have not been sufficiently met everywhere in Finland. We investigated the recorded risk factor rates of CHD and their spatial differen...

  • Article
  • Open Access
8 Citations
2,836 Views
17 Pages

7 July 2023

Mining-induced or enhanced geo-hazards (MGHs) pose significant risks in rural mountainous regions with underground mining operations by harming groundwater layers, water circulation systems, and mountain stability. MGHs occurring in naturally contami...

  • Article
  • Open Access
22 Citations
6,504 Views
17 Pages

A Predictive Model Has Identified Tick-Borne Encephalitis High-Risk Areas in Regions Where No Cases Were Reported Previously, Poland, 1999–2012

  • Pawel Stefanoff,
  • Barbara Rubikowska,
  • Jakub Bratkowski,
  • Zbigniew Ustrnul,
  • Sophie O. Vanwambeke and
  • Magdalena Rosinska

During 1999–2012, 77% of the cases of tick-borne encephalitis (TBE) were recorded in two out of 16 Polish provinces. However, historical data, mostly from national serosurveys, suggest that the disease could be undetected in many areas. The aim of th...

  • Article
  • Open Access
8 Citations
2,824 Views
14 Pages

Spatial-Temporal Variations for Pollution Assessment of Heavy Metals in Hengshui Lake of China

  • Weiwei Liu,
  • Ziliang Guo,
  • Henian Wang,
  • Daan Wang and
  • Manyin Zhang

2 February 2022

A comprehensive analysis of the spatial and temporal variations of heavy metals in wetland sediment can delineate the changes in possible contamination sources, providing valuable conservation strategies for further wetland management. Using the poll...

  • Brief Report
  • Open Access
1,682 Views
5 Pages

17 July 2024

Precancerous and cancerous lesions of the uterine cervix are known to be associated with Human Papillomavirus (HPV) infection. The screening of high-risk (HR)-HPV infection in the female population has led to the discovery of several cases of a doubl...

  • Article
  • Open Access
21 Citations
4,518 Views
13 Pages

The Spread of NDM-1 and NDM-7-Producing Klebsiella pneumoniae Is Driven by Multiclonal Expansion of High-Risk Clones in Healthcare Institutions in the State of Pará, Brazilian Amazon Region

  • Yan Corrêa Rodrigues,
  • Amália Raiana Fonseca Lobato,
  • Ana Judith Pires Garcia Quaresma,
  • Lívia Maria Guimarães Dutra Guerra and
  • Danielle Murici Brasiliense

14 December 2021

Carbapenem resistance among Klebsiella pneumoniae isolates is often related to carbapenemase genes, located in genetic transmissible elements, particularly the blaKPC gene, which variants are spread in several countries. Recently, reports of K. pneum...

  • Article
  • Open Access
37 Citations
8,438 Views
11 Pages

Effectiveness of Folic Acid Fortified Flour for Prevention of Neural Tube Defects in a High Risk Region

  • Haochen Wang,
  • Hans De Steur,
  • Gong Chen,
  • Xiaotian Zhang,
  • Lijun Pei,
  • Xavier Gellynck and
  • Xiaoying Zheng

9 March 2016

Despite efforts to tackle folate deficiency and Neural Tube Defects (NTDs) through folic acid fortification, its implementation is still lacking where it is needed most, highlighting the need for studies that evaluate the effectiveness of folic acid...

  • Article
  • Open Access
13 Citations
3,091 Views
13 Pages

6 April 2023

Antimicrobial-resistant Escherichia coli isolates have emerged in various ecologic compartments and evolved to spread globally. We sought to (1.) investigate the occurrence of ESBL-producing E. coli (ESBL-Ec) in feces from free-range chickens in a ru...

  • Article
  • Open Access
3 Citations
2,715 Views
12 Pages

Overall, there has been an increasing trend in the perceived risk of harm from smoking among U.S. high school seniors. However, these perceptions of risk have been falling in recent years. This study uses regional-level panel data from the Monitoring...

  • Article
  • Open Access
1 Citations
2,116 Views
17 Pages

Children’s readjustment to preschool following long-term school closures during the COVID-19 pandemic merits special attention. This study examined children’s preschool readjustment using a survey of 1008 teachers in a high-risk region an...

  • Article
  • Open Access
7 Citations
4,682 Views
17 Pages

3 January 2024

High-rise buildings (HRBs) are prone to high fire hazards due to their high occupant density, limited evacuation routes, and high fire load. The indicator system method, as a systematic evaluation method, is widely applied to assess HRB fire risk. Ho...

  • Review
  • Open Access
16 Citations
4,806 Views
14 Pages

21 July 2022

High-risk cSCC is defined as invasive cSCC staged as N0 (without detectable regional lymph nodes) and M0 (without distant metastasis), that has features associated with a higher risk of poorer prognosis. The focus of this review is on the recent adva...

  • Article
  • Open Access
24 Citations
9,949 Views
13 Pages

Is Dog Owner Obesity a Risk Factor for Canine Obesity? A “One-Health” Study on Human–Animal Interaction in a Region with a High Prevalence of Obesity

  • Lourdes Suarez,
  • Inmaculada Bautista-Castaño,
  • Cristina Peña Romera,
  • José Alberto Montoya-Alonso and
  • Juan Alberto Corbera

Obesity in humans is a growing global problem and is one of the greatest public health challenges we face today. Most researchers agree that, as in humans, the incidence in the companion animal population is also increasing. The aim of this study was...

  • Article
  • Open Access
1 Citations
1,897 Views
14 Pages

26 August 2024

Wild-grown edible mushrooms are important in world diets and are also efficient metal accumulators. Yunnan, Southwest China, is the main producing region, with typically high levels of geochemical metals. The environmental factors, bioaccumulation, d...

  • Article
  • Open Access
1 Citations
1,505 Views
11 Pages

Whole Exome-Wide Association Identifies Rare Variants in APC Associated with High-Risk Colorectal Cancer in the Middle East

  • Abdul Khalid Siraj,
  • Rong Bu,
  • Saud Azam,
  • Zeeshan Qadri,
  • Kaleem Iqbal,
  • Sandeep Kumar Parvathareddy,
  • Fouad Al-Dayel and
  • Khawla S. Al-Kuraya

4 November 2024

Background: Colorectal cancer (CRC) displays a complex pattern of inheritance. It is postulated that much of the missing heritability of CRC is enriched in high-impact rare alleles, which might play a crucial role in the etiology and susceptibility o...

  • Article
  • Open Access
1 Citations
2,339 Views
9 Pages

24 November 2023

Background: With the growing incidence of breast cancer, efficient and correct staging is essential for further treatment decisions. Axillary ultrasound (US) remains the most common method for regional nodal involvement assessment. The aim of this st...

  • Article
  • Open Access
3 Citations
2,006 Views
20 Pages

Comprehensive Zoning Strategies for Flood Disasters in China

  • Huipan Li,
  • Yuan Wang,
  • Liying Ping,
  • Na Li and
  • Peng Zhao

9 September 2024

The frequency of global floods has increased, posing significant threats to economic development and human safety. Existing flood risk zoning studies in disaster prevention lack integration of the natural–economic–social chain and urban r...

  • Article
  • Open Access
1 Citations
1,947 Views
23 Pages

15 April 2025

The unique features of high-quality agri-food production are rooted in the specificities of ecosystems, interpreted through an anthropocentric lens. In Italy, such products are nationally certified with labels that enhance both their market value and...

  • Article
  • Open Access
1 Citations
1,010 Views
21 Pages

The Ecological Risks and Invasive Potential of Introduced Ornamental Plants in China

  • Haoyu Wang,
  • Min Yang,
  • Xiaohua Ma,
  • Qingdi Hu,
  • Lei Feng,
  • Yaping Hu,
  • Jiehui He,
  • Xule Zhang and
  • Jian Zheng

30 April 2025

The import of ornamental plants has become a major source of alien invasive plants in China, posing threats to local ecosystems. However, research on their invasive potential and management strategies remains limited. This study evaluated the invasio...

  • Review
  • Open Access
7 Citations
4,413 Views
13 Pages

Resting State EEG Correlates of Suicide Ideation and Suicide Attempt

  • Francesco Amico,
  • Richard E. Frye,
  • Scott Shannon and
  • Steve Rondeau

Suicide is a global phenomenon that impacts individuals, families, and communities from all income groups and all regions worldwide. While it can be prevented if personalized interventions are implemented, more objective and reliable diagnostic metho...

  • Article
  • Open Access
3 Citations
2,373 Views
10 Pages

In recent years, metabolic syndrome has become one of the leading causes of death in Taiwan. This study proposes a classification and clustering method specific to the administrative regions of New Taipei City to explore the incidence and correspondi...

  • Article
  • Open Access
4 Citations
4,917 Views
23 Pages

16 December 2023

Under global warming, flooding has become one of the most destructive natural disasters along the China–Pakistan Economic Corridor (CPEC), which significantly jeopardizes the construction and ongoing stability of the CPEC. The assessment of reg...

  • Article
  • Open Access
5 Citations
3,321 Views
25 Pages

Knowledge of geographical disparities in myocardial infarction (MI) is critical for guiding health planning and resource allocation. The objectives of this study were to identify geographic disparities in MI hospitalization risks in Florida and asses...

  • Article
  • Open Access
1 Citations
1,976 Views
22 Pages

12 July 2024

Investigating the distribution characteristics of earthquake disaster risks in the Sichuan–Yunnan region is of great importance for enhancing government emergency response capabilities and achieving sustainable regional development. This study,...

  • Article
  • Open Access
2 Citations
5,270 Views
14 Pages

15 March 2022

Given the substantial economic damage caused by the continual circulation of highly pathogenic avian influenza (HPAI) outbreaks since 2003, identifying high-risk locations associated with HPAI infections is essential. In this study, using affected an...

  • Article
  • Open Access
2,182 Views
16 Pages

Meningococcal Vaccination in High-Risk Patients: A Systematic Approach to Evaluating Coverage and Patient Catch-Up Through Healthcare Databases

  • Rafael Ruiz-Montero,
  • Álvaro Serrano-Ortiz,
  • Mario Rivera-Izquierdo,
  • Piedad Galvache Murillo-Rico,
  • Ana Moñiz-Díez,
  • María Ángeles Onieva-García,
  • Eloy Girela-López and
  • Inmaculada Salcedo-Leal

8 March 2025

Background: Invasive meningococcal disease (IMD) can lead to severe and fatal outcomes. Vaccines against meningococcus (serogroups B, MenB; or ACWY, MenACWY) are recommended for patients at high risk of developing IMD. Our aim was to identify high-ri...

  • Article
  • Open Access
3 Citations
2,237 Views
24 Pages

Flooding poses a significant hazard to urban areas, particularly under the pressures of climate change and rapid urbanization. This study evaluates the flood risk in the Wadi Ibrahim watershed, located in Makkah Al-Mukarramah City, Kingdom of Saudi A...

  • Article
  • Open Access
3 Citations
1,630 Views
20 Pages

Potential Impacts of Land Use Change on Ecosystem Service Supply and Demand Under Different Scenarios in the Gansu Section of the Yellow River Basin, China

  • Yingchen Bai,
  • Conghai Han,
  • Fangying Tang,
  • Zuzheng Li,
  • Huixia Tian,
  • Zhihao Huang,
  • Li Ma,
  • Xuefan Hu,
  • Jianchao Wang and
  • Bo Chen
  • + 3 authors

30 January 2025

The degradation of ecosystem services (ES) poses a significant obstacle to regional sustainable development. Land-use change is widely recognized as a pivotal factor driving the spatio-temporal dynamics of ES supply and demand. However, the future im...

  • Article
  • Open Access
1,691 Views
16 Pages

Real-World Management of High-Risk Prostate Cancer Post-Radical Prostatectomy: Insights from a Regional Quality Collaborative

  • Aaron R. Hochberg,
  • Annie H. Ho,
  • Rasheed A. M. Thompson,
  • Matthew B. Buck,
  • Costas D. Lallas,
  • Christine Ibilibor,
  • Jeffrey J. Tomaszewski,
  • Serge Ginzburg,
  • Andres Correa and
  • Robert Uzzo
  • + 14 authors

8 May 2025

Prostate cancer (CaP) remains the most diagnosed malignancy in men, and the incidence of high-grade disease at diagnosis is increasing [...]

  • Article
  • Open Access
1 Citations
1,879 Views
11 Pages

26 July 2024

Human papillomavirus (HPV) is an oncogenic DNA virus that plays a role in different cancer types. The aim of this study was to detect the prevalence and types of HPV and its relation with p16, EGFR and clinical findings in lung cancer. HPV and EGFR d...

  • Article
  • Open Access
706 Views
13 Pages

Seroprevalence of Poliovirus Types 1, 2, and 3 Among Children Aged 6–11 Months: Variations Across Survey Rounds in High-Risk Areas of Pakistan

  • Imtiaz Hussain,
  • Ahmad Khan,
  • Muhammad Umer,
  • Muhammad Sajid,
  • Haider Abbas,
  • Muhammad Masroor Alam,
  • Altaf Bosan,
  • Jeffrey Partridge,
  • Rehan Hafiz and
  • Anwar-ul Haq
  • + 1 author

19 October 2025

Background: The current polio epidemiology in Pakistan poses a unique challenge for global eradication, with polio transmission dynamics influenced by regional variations in immunity and disparities in immunization coverage. This study assesses the i...

  • Article
  • Open Access
590 Views
22 Pages

Under the dual pressures of climate change and rapid urbanization, extreme heat events pose growing risks to densely populated megaregions. The Guangdong–Hong Kong–Macao Greater Bay Area (GBA), a densely populated and economically vital r...

  • Article
  • Open Access
10 Citations
2,787 Views
20 Pages

29 November 2023

Landslides and flash floods are significant natural hazards with substantial risks to human settlements and the environment, and understanding their interconnection is vital. This research investigates the hazards of landslides and floods in two adop...

  • Article
  • Open Access
13 Citations
3,483 Views
12 Pages

Seroprevalence of SARS-CoV-2 Antibodies in Symptomatic Individuals Is Higher than in Persons Who Are at Increased Risk Exposure: The Results of the Single-Center, Prospective, Cross-Sectional Study

  • Alexandr Zurochka,
  • Maria Dobrinina,
  • Vladimir Zurochka,
  • Desheng Hu,
  • Alexandr Solovyev,
  • Liana Ryabova,
  • Igor Kritsky,
  • Roman Ibragimov and
  • Alexey Sarapultsev

The present study aimed to assess antibody seropositivity prevalence among symptomatic individuals and individuals with a high risk of occupational exposure to SARS-CoV-2. Participants from Chelyabinsk (Russian Federation) who were at an increased ri...

  • Article
  • Open Access
18 Citations
4,041 Views
23 Pages

Temporal Monitoring and Predicting of the Abundance of Malaria Vectors Using Time Series Analysis of Remote Sensing Data through Google Earth Engine

  • Fahimeh Youssefi,
  • Mohammad Javad Valadan Zoej,
  • Ahmad Ali Hanafi-Bojd,
  • Alireza Borhani Dariane,
  • Mehdi Khaki,
  • Alireza Safdarinezhad and
  • Ebrahim Ghaderpour

2 March 2022

In many studies regarding the field of malaria, environmental factors have been acquired in single-time, multi-time or a short-time series using remote sensing and meteorological data. Selecting the best periods of the year to monitor the habitats of...

  • Article
  • Open Access
6 Citations
2,720 Views
21 Pages

Spatial Zoning of Dry-Hot Wind Disasters in Shandong Province

  • Nan Wang,
  • Xiaoping Xue,
  • Lijuan Zhang,
  • Yue Chu,
  • Meiyi Jiang,
  • Yumeng Wang,
  • Yiping Yang,
  • Xihui Guo,
  • Yufeng Zhao and
  • Enbo Zhao

25 March 2022

As a major agricultural province of China, Shandong province has long ranked first in agricultural growth value among all of the provinces; at the same time, it is also the province that is most affected by dry-hot wind. Therefore, it is of great sig...

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