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Keywords = fast transient events

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22 pages, 1328 KB  
Article
A Distributed Reinforcement Learning Method for Output Consensus of Heterogeneous Multi-Agent Systems with Event-Triggered Mechanisms
by Mengna Quan, Bin Lan, Shike Long, Yongjun Wang and Shanlin Sun
Aerospace 2026, 13(6), 487; https://doi.org/10.3390/aerospace13060487 - 22 May 2026
Abstract
This paper investigates the output consensus problem in heterogeneous multi-agent systems. To address the challenges of traditional analytical methods in handling unknown dynamics and disturbances, a control framework is proposed that combines known model structures with a data-driven adaptive mechanism. The framework uses [...] Read more.
This paper investigates the output consensus problem in heterogeneous multi-agent systems. To address the challenges of traditional analytical methods in handling unknown dynamics and disturbances, a control framework is proposed that combines known model structures with a data-driven adaptive mechanism. The framework uses a distributed internal model to compensate for system heterogeneity and incorporates an event-triggered mechanism to reduce communication burden. To improve transient tracking performance, a reinforcement learning strategy based on centralized training and decentralized execution is introduced to adaptively optimize local feedback gains. Simulation results show that the proposed method effectively bounds closed-loop signals, achieves relatively fast convergence, and demonstrates some robustness and communication efficiency under process noise. Full article
(This article belongs to the Special Issue New Sights of Intelligent Robust Control in Aerospace)
27 pages, 12622 KB  
Article
Safety-Filtered Residual Reinforcement Learning over Model Predictive Control for Friction-Aware Autonomous Vehicle Platooning
by Ali S. Allahloh, Atef M. Ghaleb, Mohammad Sarfraz, Abdalla Alrashdan, Mohammed A. H. Ali and Adel Al-Shayea
Machines 2026, 14(5), 560; https://doi.org/10.3390/machines14050560 - 16 May 2026
Viewed by 189
Abstract
This paper presents a deployment-oriented longitudinal platoon-control architecture for connected and autonomous vehicles operating under repeated leader hard-braking, cut-ins, and spatially varying road friction. The proposed stack combines four elements: (i) a lightweight scalar Kalman filter (KF) that smooths a friction-related signal and [...] Read more.
This paper presents a deployment-oriented longitudinal platoon-control architecture for connected and autonomous vehicles operating under repeated leader hard-braking, cut-ins, and spatially varying road friction. The proposed stack combines four elements: (i) a lightweight scalar Kalman filter (KF) that smooths a friction-related signal and feeds friction-dependent constraint tightening; (ii) a model predictive control (MPC) backbone whose weights and horizon are selected offline using multi-objective GA/NSGA-II tuning; (iii) a bounded proximal policy optimization (PPO) residual policy, trained with the aid of a learned surrogate model, that refines the MPC command during transient events; and (iv) a command-level safety projection that enforces instantaneous actuation and clearance constraints at the fast control tick. The contribution is therefore not a new MPC formulation or a new reinforcement-learning algorithm in isolation, but an integrated and experimentally characterized control stack that keeps the safety-critical structure explicit while using learning to improve transient behavior. The method is evaluated in a CARLA digital twin of a six-vehicle platoon over a 5 km mixed urban–highway route and is further assessed in hardware-in-the-loop (HIL) on an automotive ECU using a multi-rate ROS 2/AUTOSAR implementation (50 Hz estimation/safety loop, 10 Hz MPC/RL refresh). Across 10 held-out disturbance seeds, the full stack improves spacing regulation, maintains non-amplifying disturbance propagation according to the reported string-stability indices, and reduces a route-normalized positive tractive-energy-at-the-wheels proxy by about 12% relative to Manual MPC and by up to 18% relative to a PID-CACC reference. Because the PID-CACC baseline does not enforce hard constraints and can collide under the tested disturbance suite, the main performance comparison is among collision-free controllers. The friction signal used in CARLA is derived from simulator road-surface annotations before filtering, so the present study should be interpreted as a friction-aware control and integration study rather than a validated onboard friction-estimation result. Likewise, the reported energy metric is an effort proxy and is not a calibrated fuel or battery consumption model. Full article
(This article belongs to the Special Issue Reinforcement Learning for Autonomous Vehicle Control)
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20 pages, 8145 KB  
Article
Research on the Activation Strategies of Passive Decay Heat Removal Systems in a Pool-Type SFR by Three-Dimensional Numerical Simulation
by Yue Liu, Yuhao Zhang, Ruoyu Liu, Xinyi Chen, Haijie Song and Daogang Lu
J. Nucl. Eng. 2026, 7(2), 35; https://doi.org/10.3390/jne7020035 - 10 May 2026
Viewed by 318
Abstract
A Decay Heat Removal System (DHRS) is an essential passive safety feature in pool-type Sodium-Cooled Fast Reactors (SFRs), maintaining core temperatures within design limits via natural circulation after reactor scram. Operation of the DHRS is regulated by the damper of the Air Heat [...] Read more.
A Decay Heat Removal System (DHRS) is an essential passive safety feature in pool-type Sodium-Cooled Fast Reactors (SFRs), maintaining core temperatures within design limits via natural circulation after reactor scram. Operation of the DHRS is regulated by the damper of the Air Heat Exchanger (AHX), which controls its activation and shutdown. In the current design guidelines, it is typically recommended to initiate the Decay Heat Exchanger (DHX) at 600 s after a Station Blackout (SBO) event. However, this activation timing requires minor dynamic adjustment based on the transient response of the system, which can be obtained by either real-reactor experiments or numerical simulations. Since full-scale real-reactor experiments are not easy to conduct, numerical simulations are effective ways to enhance the passive safety performance of pool-type SFRs under SBO conditions, clarify the regulatory mechanism of DHX activation timing on system behavior, and optimize DHRS operational strategies. This study developed an integrated full-reactor three-dimensional numerical model that comprehensively incorporated key components such as the core, sodium pools, and DHX. Transient variations in power and boundary conditions were precisely controlled via User-Defined Functions (UDFs). The impact of different DHX activation strategies on the reactor’s decay heat removal capability was systematically analyzed. Three-dimensional numerical simulations were performed for three representative DHX operational strategies, immediate activation post-accident (0 s), delayed activation per the standard strategy (600 s), and complete DHX non-activation, yielding detailed temperature and flow field distributions within the reactor. Results demonstrate that under the standard strategy, not only can the temperature in the pool be controlled below the safety limit (550 °C) in the early stage but the temperature can also drop in the subsequent stage while retaining a 600 s safe operation threshold. Notably, the results reveal that “sooner is not always better”. Immediate DHX activation accelerates internal circulation and drives hot fluid downwards, paradoxically heating the cold pool faster than delayed activation, thereby resulting in a higher core outlet temperature. This study contributes to enhancing the credibility of passive safety in SFRs and provides reliable data to support the development of optimized reactor operation protocols. Full article
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24 pages, 5021 KB  
Article
A Fast Transient Low-Dimensional Cavity Modeling Methodology Incorporating the Coupled Effects of Volume Compliance and Inertial Forces
by Kang Zuo, Chuankai Liu and Jiajun Wang
Aerospace 2026, 13(5), 437; https://doi.org/10.3390/aerospace13050437 - 8 May 2026
Viewed by 223
Abstract
Existing low-dimensional cavity element models developed under the lumped-parameter assumption, which neglect cavity geometric parameters and inertial effects within the cavity, cannot meet the simulation requirements of aircraft-engine secondary air systems (SAS) during the fast transient response processes. To address this gap, this [...] Read more.
Existing low-dimensional cavity element models developed under the lumped-parameter assumption, which neglect cavity geometric parameters and inertial effects within the cavity, cannot meet the simulation requirements of aircraft-engine secondary air systems (SAS) during the fast transient response processes. To address this gap, this study proposes a modular modeling methodology for a fast transient cavity low-dimensional model. The cavity is partitioned into modules according to the internal flow features during the fast transient response, and the partition ratios are determined by evaluating how different geometric parameters affect these flow characteristics. Using this method, low-dimensional models are constructed for single-port cavities and dual-port cavities under various geometric parameters, and the fast transient depressurization response is investigated. In parallel, corresponding three-dimensional models are established using a validated simulation approach, and three-dimensional computations are performed. Comparison between the low-dimensional and three-dimensional results confirms that the proposed method effectively reproduces the key flow phenomena in the cavity during the fast transient events with credible predictive accuracy. This work optimizes existing low-dimensional simulation algorithms for air systems and provides technical support for studying fast transient responses in aircraft-engine SAS. Full article
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17 pages, 710 KB  
Article
Modeling of Three-Phase Transformers for Naval Applications Considering Transient Analysis
by Marcelo Cairo Pereira, Felipe Proença de Albuquerque, Eduardo Coelho Marques da Costa and Pablo Torrez Caballero
Energies 2026, 19(8), 1877; https://doi.org/10.3390/en19081877 - 12 Apr 2026
Viewed by 372
Abstract
This paper presents a systematic methodology for time-domain modeling of three-phase power transformers aimed at electromagnetic transient analysis in shipboard and embedded electrical systems. Accurate modeling of transformers in such environments is critical, as naval power systems are subject to strict electromagnetic compatibility [...] Read more.
This paper presents a systematic methodology for time-domain modeling of three-phase power transformers aimed at electromagnetic transient analysis in shipboard and embedded electrical systems. Accurate modeling of transformers in such environments is critical, as naval power systems are subject to strict electromagnetic compatibility (EMC) requirements and are particularly susceptible to fast transients caused by switching operations, fault events, and nonlinear loads operating in confined and isolated grids. The proposed approach combines the Vector Fitting (VF) algorithm with Clarke modal decomposition to obtain stable, passive, and causal rational approximations of the frequency-dependent admittance matrix over a wide frequency range. The admittance matrix is first identified from frequency-domain measurements or simulations, capturing the transformer’s terminal behavior across multiple frequency sub-bands. Clarke’s transformation is then applied to decouple the three-phase system into independent modal components—namely the zero-sequence and positive-sequence modes, reducing the original multi-phase problem to a set of independent single-phase systems. This modal decoupling significantly improves computational efficiency without sacrificing accuracy, as each mode can be fitted and simulated independently. Full article
(This article belongs to the Special Issue Advanced Electric Power Systems, 2nd Edition)
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28 pages, 6179 KB  
Article
Robust Voltage Stability Enhancement of DFIG Systems Using Deadbeat-Controlled STATCOM and ADRC-Based Supercapacitor Support
by Ahmed Muthanna Nori, Ali Kadhim Abdulabbas, Omar Alrumayh and Tawfiq M. Aljohani
Mathematics 2026, 14(8), 1254; https://doi.org/10.3390/math14081254 - 9 Apr 2026
Viewed by 340
Abstract
The increasing penetration of Doubly Fed Induction Generator (DFIG)-based wind energy systems raises major concerns regarding voltage stability and Fault Ride-Through (FRT) capability under grid disturbances and wind speed variations. This paper proposes a coordinated control framework for a grid-connected DFIG system, where [...] Read more.
The increasing penetration of Doubly Fed Induction Generator (DFIG)-based wind energy systems raises major concerns regarding voltage stability and Fault Ride-Through (FRT) capability under grid disturbances and wind speed variations. This paper proposes a coordinated control framework for a grid-connected DFIG system, where a Static Synchronous Compensator (STATCOM) based on discrete-time deadbeat current control is integrated with a Supercapacitor Energy Storage System (SCES) connected to the DC link through a bidirectional DC-DC converter governed by cascaded Active Disturbance Rejection Control (ADRC). The deadbeat-controlled STATCOM provides fast reactive current injection for voltage support during sag and swell events, while the cascaded ADRC enhances DC-link voltage regulation and suppresses rotor-speed oscillations. Comprehensive MATLAB/Simulink simulations are carried out under variable wind speed and severe grid disturbances up to 80% voltage sag and 50% voltage swell. For voltage regulation, the proposed method is compared with SVC and PI-based STATCOM. In addition, SCES control performance is evaluated by comparing PI, single ADRC, and cascaded ADRC in terms of DC-link voltage overshoot, undershoot, and ripple. The results show clear improvements in voltage response and transient performance. Under a 20% voltage sag, the proposed deadbeat-controlled STATCOM significantly improves the dynamic response, where the undershoot is reduced from 0.125 p.u. (with SVC) to 0.04 p.u., and the settling time is shortened from 0.04 s to 0.025 s. Under a severe 80% sag, the overshoot is limited to 0.02 p.u., compared with 0.13 p.u. for the SVC and 0.15 p.u. for the PI-based STATCOM. Similarly, under a 50% voltage swell, the overshoot is reduced to 0.20 p.u., compared with 0.46 p.u. for the SVC and 0.27 p.u. for the PI-based STATCOM. Regarding the DC-link performance under 80% sag, the proposed cascaded ADRC-based SCES limits the overshoot and undershoot to 6 V and 2 V, respectively, compared with 39 V and 32 V for the PI-based SCES. These results confirm the superior damping, disturbance rejection, and FRT enhancement achieved by the proposed strategy. Full article
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24 pages, 614 KB  
Review
Fasting-Based Dietary Interventions in Cancer Patients and Survivors: A Scoping Review
by Kuang-Yi Wen, Julianne Freedman, Abenezer Tafese, William Kelly and Nicole Simone
Nutrients 2026, 18(7), 1035; https://doi.org/10.3390/nu18071035 - 25 Mar 2026
Cited by 1 | Viewed by 1640
Abstract
Background: Fasting-based interventions are increasingly investigated as adjuncts to cancer treatment for the potential to reduce therapy-related toxicities, improve metabolic health, and enhance quality of life. However, clinical evidence regarding their efficacy, tolerability, and acceptability remains limited and fragmented. This scoping review [...] Read more.
Background: Fasting-based interventions are increasingly investigated as adjuncts to cancer treatment for the potential to reduce therapy-related toxicities, improve metabolic health, and enhance quality of life. However, clinical evidence regarding their efficacy, tolerability, and acceptability remains limited and fragmented. This scoping review aimed to systematically map the current evidence on fasting-based interventions in cancer patients and survivors. Methods: A literature search was conducted in PubMed, Scopus, Web of Science, and CINAHL up to 10 June 2025. Eligible interventional studies included cancer patients or survivors and evaluated fasting-based interventions, such as time-restricted eating, intermittent fasting, short-term fasting, or fasting-mimicking diets. Studies were categorized by fasting types and outcomes like fatigue, treatment toxicity, metabolic and hematologic parameters, weight, quality of life, adherence, acceptability, illness perception, and adverse events were assessed. Result: Twenty interventional studies of FMD, TRE, STF, IF, or fasting combined with altered dietary approaches conducted across 10 countries were included, comprising a total of 871 participants. Participant ages ranged from 28 to 75 years. Overall, 9 of 20 studies exclusively enrolled breast cancer patients or survivors, and chemotherapy was the most common treatment context in 11 studies. Five of six studies reported reductions in fatigue. Among the five studies assessing quality of life, one demonstrated improvement, three reported no change, and one yielded mixed results. Six of eight studies reported reductions in chemotherapy-related toxicity, and weight loss was observed in 10 of 12 studies. Reductions in IGF-1 and insulin levels were reported in six of seven and four of five studies, respectively. Hematologic changes were noted in six studies, and only one study assessed illness perceptions, reporting positive findings. Fasting-related adverse events, reported in nine studies, were generally mild and transient. High adherence and acceptability were observed across studies; however, findings were heterogeneous across intervention types and were largely derived from small or moderate-strength studies. A descriptive quality metric assessment indicated that most studies were of moderate methodological strength. More intensive fasting protocols, such as FMD and STF, appeared to demonstrate more consistent metabolic effects, whereas TRE showed higher adherence but more variable clinical outcomes. Conclusions: Fasting-based interventions have the potential to be feasible and well tolerated among cancer patients and survivors, with early evidence suggesting benefits in reducing fatigue, minimizing treatment-related toxicities, and favorable metabolic effects. Large, well-designed trials including diverse cancer populations are needed to confirm long-term outcomes and guide clinical integration. Full article
(This article belongs to the Special Issue Intermittent Fasting: Health Impacts and Therapeutic Potential)
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40 pages, 16924 KB  
Article
Event-Triggered Extension of Duty-Ratio-Based MPDSC with Field Weakening for PMSM Drives in EV Applications
by Tarek Yahia, Z. M. S. Elbarbary, Saad A. Alqahtani and Abdelsalam A. Ahmed
Machines 2026, 14(2), 137; https://doi.org/10.3390/machines14020137 - 24 Jan 2026
Cited by 1 | Viewed by 555
Abstract
This paper proposes an event-triggered extension of duty-ratio-based model predictive direct speed control (DR-MPDSC) for permanent magnet synchronous motor (PMSM) drives in electric vehicle (EV) applications. The main contribution is the development of an event-triggered execution framework specifically tailored to DR-MPDSC, in which [...] Read more.
This paper proposes an event-triggered extension of duty-ratio-based model predictive direct speed control (DR-MPDSC) for permanent magnet synchronous motor (PMSM) drives in electric vehicle (EV) applications. The main contribution is the development of an event-triggered execution framework specifically tailored to DR-MPDSC, in which control updates are performed only when the speed tracking error violates a prescribed condition, rather than at every sampling instant. Unlike conventional MPDSC and time-triggered DR-MPDSC schemes, the proposed strategy achieves a significant reduction in control execution frequency while preserving fast dynamic response and closed-loop stability. An optimized duty-ratio formulation is employed to regulate the effective application duration of the selected voltage vector within each sampling interval, resulting in reduced electromagnetic torque ripple and improved stator current quality. An extended Kalman filter (EKF) is integrated to estimate rotor speed and load torque, enabling disturbance-aware predictive speed control without mechanical torque sensing. Furthermore, a unified field-weakening strategy is incorporated to ensure wide-speed-range operation under constant power constraints, which is essential for EV traction systems. Simulation and experimental results demonstrate that the proposed event-triggered DR-MPDSC achieves steady-state speed errors below 0.5%, limits electromagnetic torque ripple to approximately 2.5%, and reduces stator current total harmonic distortion (THD) to 3.84%, compared with 5.8% obtained using conventional MPDSC. Moreover, the event-triggered mechanism reduces control update executions by up to 87.73% without degrading transient performance or field-weakening capability. These results confirm the effectiveness and practical viability of the proposed control strategy for high-performance PMSM drives in EV applications. Full article
(This article belongs to the Section Electrical Machines and Drives)
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18 pages, 1419 KB  
Review
How the Vestibular Labyrinth Encodes Air-Conducted Sound: From Pressure Waves to Jerk-Sensitive Afferent Pathways
by Leonardo Manzari
J. Otorhinolaryngol. Hear. Balance Med. 2026, 7(1), 5; https://doi.org/10.3390/ohbm7010005 - 14 Jan 2026
Viewed by 1178
Abstract
Background/Objectives: The vestibular labyrinth is classically viewed as a sensor of low-frequency head motion—linear acceleration for the otoliths and angular velocity/acceleration for the semicircular canals. However, there is now substantial evidence that air-conducted sound (ACS) can also activate vestibular receptors and afferents in [...] Read more.
Background/Objectives: The vestibular labyrinth is classically viewed as a sensor of low-frequency head motion—linear acceleration for the otoliths and angular velocity/acceleration for the semicircular canals. However, there is now substantial evidence that air-conducted sound (ACS) can also activate vestibular receptors and afferents in mammals and other vertebrates. This sound sensitivity underlies sound-evoked vestibular-evoked myogenic potentials (VEMPs), sound-induced eye movements, and several clinical phenomena in third-window pathologies. The cellular and biophysical mechanisms by which a pressure wave in the cochlear fluids is transformed into a vestibular neural signal remain incompletely integrated into a single framework. This study aimed to provide a narrative synthesis of how ACS activates the vestibular labyrinth, with emphasis on (1) the anatomical and biophysical specializations of the maculae and cristae, (2) the dual-channel organization of vestibular hair cells and afferents, and (3) the encoding of fast, jerk-rich acoustic transients by irregular, striolar/central afferents. Methods: We integrate experimental evidence from single-unit recordings in animals, in vitro hair cell and calyx physiology, anatomical studies of macular structure, and human clinical data on sound-evoked VEMPs and sound-induced eye movements. Key concepts from vestibular cellular neurophysiology and from the physics of sinusoidal motion (displacement, velocity, acceleration, jerk) are combined into a unified interpretative scheme. Results: ACS transmitted through the middle ear generates pressure waves in the perilymph and endolymph not only in the cochlea but also in vestibular compartments. These waves produce local fluid particle motions and pressure gradients that can deflect hair bundles in selected regions of the otolith maculae and canal cristae. Irregular afferents innervating type I hair cells in the striola (maculae) and central zones (cristae) exhibit phase locking to ACS up to at least 1–2 kHz, with much lower thresholds than regular afferents. Cellular and synaptic specializations—transducer adaptation, low-voltage-activated K+ conductances (KLV), fast quantal and non-quantal transmission, and afferent spike-generator properties—implement effective high-pass filtering and phase lead, making these pathways particularly sensitive to rapid changes in acceleration, i.e., mechanical jerk, rather than to slowly varying displacement or acceleration. Clinically, short-rise-time ACS stimuli (clicks and brief tone bursts) elicit robust cervical and ocular VEMPs with clear thresholds and input–output relationships, reflecting the recruitment of these jerk-sensitive utricular and saccular pathways. Sound-induced eye movements and nystagmus in third-window syndromes similarly reflect abnormally enhanced access of ACS-generated pressure waves to canal and otolith receptors. Conclusions: The vestibular labyrinth does not merely “tolerate” air-conducted sound as a spill-over from cochlear mechanics; it contains a dedicated high-frequency, transient-sensitive channel—dominated by type I hair cells and irregular afferents—that is well suited to encoding jerk-rich acoustic events. We propose that ACS-evoked vestibular responses, including VEMPs, are best interpreted within a dual-channel framework in which (1) regular, extrastriolar/peripheral pathways encode sustained head motion and low-frequency acceleration, while (2) irregular, striolar/central pathways encode fast, sound-driven transients distinguished by high jerk, steep onset, and precise spike timing. Full article
(This article belongs to the Section Otology and Neurotology)
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20 pages, 1581 KB  
Article
An Improved Variable Step-Size Normalized Subband Adaptive Filtering Algorithm for Signal Clipping Distortion
by Jiapeng Duan and Bo Zhang
Signals 2025, 6(4), 74; https://doi.org/10.3390/signals6040074 - 12 Dec 2025
Cited by 1 | Viewed by 1139
Abstract
The safe and stable operation of power systems and other dynamic systems relies on accurate perception of their dynamic processes. Voltage, current, and other measurement signals carry critical information about the system’s state. However, under conditions such as equipment damage, aging, and non-ideal [...] Read more.
The safe and stable operation of power systems and other dynamic systems relies on accurate perception of their dynamic processes. Voltage, current, and other measurement signals carry critical information about the system’s state. However, under conditions such as equipment damage, aging, and non-ideal operational conditions of devices under test, over-range phenomena may occur, leading to biased estimation issues in adaptive filters. To address this problem, this paper proposes a variable-parameter subband adaptive filtering algorithm with signal clipping distortion awareness. The algorithm first uses the Expectation-Maximization (EM) process to achieve high-fidelity restoration of damaged signals. Then, by integrating an intelligent steady-state detector and a dual-mode control mechanism, the adaptive filter can adjust key parameters such as step-size, forgetting factor, and regularization parameter based on state perception results. Finally, theoretical analysis proves the unbiased nature of the proposed method. Validation using real-world data from a high-penetration renewable energy power system shows that the algorithm achieves fast tracking during transient events and provides high-precision estimation during steady-state operation, offering an effective solution for real-time, high-accuracy processing of dynamic measurement data in power systems. Full article
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12 pages, 2027 KB  
Article
A Single-Event Transient Tolerant Multi-Loop Hybrid Low-Dropout Regulator in 28-nm CMOS Technology
by Zexin Hu, Fangchun Hu and Zhuojun Chen
Electronics 2025, 14(23), 4569; https://doi.org/10.3390/electronics14234569 - 21 Nov 2025
Viewed by 717
Abstract
Low-dropout regulators (LDOs) are critical modules in aerospace electronic systems. However, they are susceptible to single-event transient effects, which can impact the stability of the power system. Currently, almost all aerospace LDOs employ analog design to achieve robust output current characteristics. In this [...] Read more.
Low-dropout regulators (LDOs) are critical modules in aerospace electronic systems. However, they are susceptible to single-event transient effects, which can impact the stability of the power system. Currently, almost all aerospace LDOs employ analog design to achieve robust output current characteristics. In this paper, three LDO architectures including analog LDO, digital LDO, and hybrid LDO are investigated, and a novel multi-loop hybrid LDO featuring analog proportional and digital integral control is proposed. A load detection module is introduced to allow the analog loop to operate independently under light-load conditions, thereby eliminating limit cycle oscillation (LCO) issues. In addition, a falling edge detection module is implemented to accelerate the transient response of the circuit. Three LDO circuits are designed using a 28 nm CMOS process, and their single-event transient responses are compared using double-exponential current pulse simulations. The results show that the proposed hybrid LDO exhibits the strongest transient response and best immunity to single-event effects under heavy-load conditions, achieving an efficiency of 99.975%. Full article
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25 pages, 7207 KB  
Article
Feeding for Well-Being: Porcine Blood Hydrolysate Supplementation Improves Metabolic and Welfare-Related Traits in Farmed Gilthead Sea Bream (Sparus aurata)
by Cristina Moreno-Mariscal, Paul Holhorea, Federico Moroni, Leticia Mora, Fidel Toldrá and Jaume Pérez-Sánchez
Int. J. Mol. Sci. 2025, 26(21), 10725; https://doi.org/10.3390/ijms262110725 - 4 Nov 2025
Cited by 1 | Viewed by 1180
Abstract
The revalorization of animal by-products, such as porcine blood, is a key strategy for sustainable aquaculture and circular economy practices. This study aimed to fill the existing knowledge gap on the effects of spray-dried porcine blood hydrolysate (PBSH), assessing its potential as a [...] Read more.
The revalorization of animal by-products, such as porcine blood, is a key strategy for sustainable aquaculture and circular economy practices. This study aimed to fill the existing knowledge gap on the effects of spray-dried porcine blood hydrolysate (PBSH), assessing its potential as a functional feed ingredient for gilthead sea bream. Two practical diets were formulated: a control diet containing 5% blood meal, and a PBSH diet including 5% PBSH previously characterized in vitro. The results indicated that the PBSH diet promoted lower hepatosomatic index, a down-regulation of key hepatic lipogenic enzymes (scd1b, hl, lpl), and a better stress condition with lower circulating levels of glucose and cortisol and a reduction in aggressive attacks. Positive findings were also achieved in energy management, obtaining lower metabolic rates along with an enhanced swimming performance (20% increase in the critical speed) and a quicker weigh recovery after a fasting period. The PBSH diet also shaped the intestinal bacterial composition, determining a redistribution of abundant genera including Aureimonas and Halomonas. Ultimately, this study demonstrated that PBSH would act as a functional ingredient capable of enhancing fish energy management and resilience in the face of stressful events, exhibiting a transient transcriptional modulation, yet persistent physiological and welfare benefits. Full article
(This article belongs to the Special Issue Fish Nutrition, Biochemical Pathways, and Physiological Adaptations)
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50 pages, 16753 KB  
Article
Spectral Energy of High-Speed Over-Expanded Nozzle Flows at Different Pressure Ratios
by Manish Tripathi, Sławomir Dykas, Mirosław Majkut, Krystian Smołka, Kamil Skoczylas and Andrzej Boguslawski
Energies 2025, 18(21), 5813; https://doi.org/10.3390/en18215813 - 4 Nov 2025
Viewed by 1050
Abstract
This paper addresses the long-standing question of understanding the origin and evolution of low-frequency unsteadiness interactions associated with shock waves impinging on a turbulent boundary layer in transonic flow (Mach: 1.1 to 1.3). To that end, high-speed experiments in a blowdown open-channel [...] Read more.
This paper addresses the long-standing question of understanding the origin and evolution of low-frequency unsteadiness interactions associated with shock waves impinging on a turbulent boundary layer in transonic flow (Mach: 1.1 to 1.3). To that end, high-speed experiments in a blowdown open-channel wind tunnel have been performed across a convergent–divergent nozzle for different expansion ratios (PR = 1.44, 1.6, and 1.81). Quantitative evaluation of the underlying spectral energy content has been obtained by processing time-resolved pressure transducer data and Schlieren images using the following spectral analysis methods: Fast Fourier Transform (FFT), Continuous Wavelet Transform (CWT), as well as coherence and time-lag evaluations. The images demonstrated the presence of increased normal shock-wave impact for PR = 1.44, whereas the latter were linked with increased oblique λ-foot impact. Hence, significant disparities associated with the overall stability, location, and amplitude of the shock waves, as well as quantitative assertions related to spectral energy segregation, have been inferred. A subsequent detailed spectral analysis revealed the presence of multiple discrete frequency peaks (magnitude and frequency of the peaks increasing with PR), with the lower peaks linked with large-scale shock-wave interactions and higher peaks associated with shear-layer instabilities and turbulence. Wavelet transform using the Morlet function illustrates the presence of varying intermittency, modulation in the temporal and frequency scales for different spectral events, and a pseudo-periodic spectral energy pulsation alternating between two frequency-specific events. Spectral analysis of the pixel densities related to different regions, called spatial FFT, highlights the increased influence of the feedback mechanism and coupled turbulence interactions for higher PR. Collation of the subsequent coherence analysis with the previous results underscores that lower PR is linked with shock-separation dynamics being tightly coupled, whereas at higher PR values, global instabilities, vortex shedding, and high-frequency shear-layer effects govern the overall interactions, redistributing the spectral energy across a wider spectral range. Complementing these experiments, time-resolved numerical simulations based on a transient 3D RANS framework were performed. The simulations successfully reproduced the main features of the shock motion, including the downstream migration of the mean position, the reduction in oscillation amplitude with increasing PR, and the division of the spectra into distinct frequency regions. This confirms that the adopted 3D RANS approach provides a suitable predictive framework for capturing the essential unsteady dynamics of shock–boundary layer interactions across both temporal and spatial scales. This novel combination of synchronized Schlieren imaging with pressure transducer data, followed by application of advanced spectral analysis techniques, FFT, CWT, spatial FFT, coherence analysis, and numerical evaluations, linked image-derived propagation and coherence results directly to wall pressure dynamics, providing critical insights into how PR variation governs the spectral energy content and shock-wave oscillation behavior for nozzles. Thus, for low PR flows dominated by normal shock structure, global instability of the separation zone governs the overall oscillations, whereas higher PR, linked with dominant λ-foot structure, demonstrates increased feedback from the shear-layer oscillations, separation region breathing, as well as global instabilities. It is envisaged that epistemic understanding related to the spectral dynamics of low-frequency oscillations at different PR values derived from this study could be useful for future nozzle design modifications aimed at achieving optimal nozzle performance. The study could further assist the implementation of appropriate flow control strategies to alleviate these instabilities and improve thrust performance. Full article
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16 pages, 299 KB  
Article
Evaluation of Anesthesia Management During Peroral Endoscopic Myotomy in Patients with Achalasia: A Retrospective Study
by Mukadder Sanli, Sami Akbulut, Muharrem Ucar and Yilmaz Bilgic
J. Clin. Med. 2025, 14(18), 6504; https://doi.org/10.3390/jcm14186504 - 16 Sep 2025
Viewed by 2503
Abstract
Background: Achalasia is a primary esophageal motility disorder characterized by impaired relaxation of the lower esophageal sphincter (LES) and absent peristalsis, which increases the risk of aspiration during anesthesia. Peroral endoscopic myotomy (POEM) is a minimally invasive therapeutic approach requiring tailored anesthetic [...] Read more.
Background: Achalasia is a primary esophageal motility disorder characterized by impaired relaxation of the lower esophageal sphincter (LES) and absent peristalsis, which increases the risk of aspiration during anesthesia. Peroral endoscopic myotomy (POEM) is a minimally invasive therapeutic approach requiring tailored anesthetic management. This study aimed to evaluate perioperative anesthesia management during POEM, focusing on ventilation parameters, intraoperative hemodynamics, laboratory changes, and the incidence and severity of postoperative complications. Methods: A retrospective analysis was conducted on 51 patients who underwent POEM between June 2016 and April 2025. Demographic features, anesthesia techniques, intraoperative physiologic parameters, hematologic profiles, and postoperative complications were evaluated. Standard preoperative fasting protocols were implemented. Rapid sequence induction (RSI) with propofol and rocuronium was followed by endotracheal intubation. Desflurane was used for maintenance anesthesia, with ventilation settings adjusted to limit end-tidal carbon dioxide (ETCO2) elevation. Results: The median age of patients was 48 years, with a slight female (52.9%) predominance. Most patients were American Society of Anesthesiologists (ASA) II (64.7%) or ASA III (35.3%) scores and had comorbid hypertension (31.4%) or diabetes (11.8%). The median anesthesia duration was 180 min, and the peak inspiratory pressure remained stable at 25 mmHg. Oxygen saturation (SpO2) improved during the procedure, while ETCO2 increased from baseline to 49 mmHg by the end. Blood pressure declined transiently but recovered intraoperatively. Hematologic analysis showed significant increases in white blood cell (WBC) and neutrophils and mild decreases in hemoglobin, hematocrit, and platelets. Early postoperative complications included subcutaneous emphysema (19.6%), minor bleeding (9.8%), and pneumoperitoneum (7.84%). Two patients required tube thoracostomy due to pneumothorax, but no patient developed a complication requiring surgical exploration. During a median follow-up of 546 days, no mortality was reported. Long-term complications were infrequent, with gastroesophageal reflux disease (GERD) (3.92%) and esophagitis (1.96%) being the most notable. Conclusions: POEM can be performed safely with appropriate anesthetic management. Despite significant physiologic changes during carbon dioxide (CO2) insufflation, no life-threatening complications occurred, and the majority of adverse events were minor and self-limiting. Close intraoperative monitoring and interdisciplinary coordination contribute to favorable perioperative outcomes. Full article
(This article belongs to the Section Anesthesiology)
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Article
Quasar—A Process Variability-Aware Radiation Robustness Evaluation Tool
by Bernardo Borges Sandoval, Lucas Yuki Imamura, Ana Flávia D. Reis, Leonardo Heitich Brendler, Rafael B. Schvittz and Cristina Meinhardt
Electronics 2025, 14(15), 3131; https://doi.org/10.3390/electronics14153131 - 6 Aug 2025
Cited by 2 | Viewed by 1198
Abstract
This work presents Quasar, an open-source tool developed to boost the characterization of how variability effects impact radiation sensitivity in digital circuits. Quasar receives a SPICE netlist as input and automatically determines robustness metrics, such as the critical Linear Energy Transfer, for every [...] Read more.
This work presents Quasar, an open-source tool developed to boost the characterization of how variability effects impact radiation sensitivity in digital circuits. Quasar receives a SPICE netlist as input and automatically determines robustness metrics, such as the critical Linear Energy Transfer, for every configuration in which a Single Event Transient fault can propagate an error. The tool can handle ranges from small basic cells to median multi-gate circuits in a few seconds, speeding up the traditional fault injection mechanism based on a large number of electrical simulations. The tool’s workflow explores logical masking to reduce the design space exploration, i.e., reducing the necessary number of electrical simulations, as well as regression methods to speed up variability evaluations. Quasar already has shown the potential to provide useful results, and a prototype has also been published. This work presents a more polished and complete version of the tool, one that optimizes the tool’s search process and allows not only for a fast evaluation of the radiation robustness of a circuit, but also for an analysis of how fabrication process metrics impact this robustness, such as Work Function Fluctuation. Full article
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