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356 Results Found

  • Article
  • Open Access
9 Citations
3,609 Views
14 Pages

9 January 2022

Modelling the epidemic’s spread on multiplex networks, considering complex human behaviours, has recently gained the attention of many scientists. In this work, we study the interplay between epidemic spreading and opinion dynamics on multiplex...

  • Review
  • Open Access
3 Citations
2,714 Views
16 Pages

Decoding Molecular Network Dynamics in Cells: Advances in Multiplexed Live Imaging of Fluorescent Biosensors

  • Qiaowen Chen,
  • Yichu Xu,
  • Jhen-Wei Wu,
  • Jr-Ming Yang and
  • Chuan-Hsiang Huang

17 September 2025

Genetically encoded fluorescent protein (FP)-based biosensors have revolutionized cell biology research by enabling real-time monitoring of molecular activities in live cells with exceptional spatial and temporal resolution. Multiplexed biosensing ad...

  • Article
  • Open Access
2 Citations
4,106 Views
13 Pages

The Time Division Multiple Access (TDMA) scheme has been proposed as the one which assures real-time messaging in a networking system. In the TDMA scheme, a networking system operates based on time slots which are defined as discrete time units. Some...

  • Article
  • Open Access
13 Citations
5,558 Views
15 Pages

25 February 2019

A dynamic phase measuring profilometry (PMP) based on tricolor binary fringe combined time-division multiplexing principle is proposed. Only one tricolor binary fringe combined by red (R), green (G), and blue (B) binary fringes with the same fringe w...

  • Article
  • Open Access
712 Views
23 Pages

Monitoring High-Dynamic Wideband Orthogonal Frequency Division Multiplexing Signal Under Weak Prior Knowledge

  • Chaoqun Hou,
  • Linan Wang,
  • Yuqing Wang,
  • Xiangni Zou,
  • Jianbo Liu,
  • Teng Hou,
  • Zehui Zhang and
  • Jianxiong Pan

In the context of the escalating requirement for high-throughput multimedia services, Orthogonal Frequency Division Multiplexing (OFDM) signal systems have become increasingly prevalent in Low Earth Orbit (LEO) satellite communications. In order to p...

  • Article
  • Open Access
17 Citations
4,650 Views
13 Pages

12 February 2021

The 3GPP standardized the physical layer specification in 5G New Radio to support enhanced mobile broadband (eMBB) and ultra-reliable low-latency communication (URLLC) coexistence in usage scenarios including aerial vehicles (AVs). Dynamic multiplexi...

  • Article
  • Open Access
10 Citations
2,778 Views
13 Pages

LiNEV: Visible Light Networking for Connected Vehicles

  • Osama Saied,
  • Omprakash Kaiwartya,
  • Mohammad Aljaidi,
  • Sushil Kumar,
  • Mufti Mahmud,
  • Rupak Kharel,
  • Farah Al-Sallami and
  • Charalampos C. Tsimenidis

11 August 2023

DC-biased optical orthogonal frequency division multiplexing (DCO-OFDM) has been introduced to visible light networking framework for connected vehicles (LiNEV) systems as a modulation and multiplexing scheme. This is to overcome the light-emitting d...

  • Article
  • Open Access
1 Citations
1,776 Views
15 Pages

Performance of Dynamic Time Division Broadcast Protocol with Rateless Coding

  • Kun Xu,
  • Makun Guo,
  • Chule Yang,
  • Bin Jiang and
  • Zhiyong Du

20 December 2019

Two-way relaying channel (TWRC) improves the throughput of one-way relaying channel through network coding at the relay. Time division broadcast (TDBC) is one typical protocol for TWRC, but with three time slots for one round information exchange lea...

  • Article
  • Open Access
2,203 Views
14 Pages

Hardware Acceleration of Identifying Barcodes in Multiplexed Nanopore Sequencing

  • Wenjie Hu,
  • Yuxin Zhang,
  • Hongrui Zhang and
  • Weigang Chen

19 August 2022

In multiplexed sequencing, the identification of DNA sequencing barcodes can effectively reduce the probability of sample misassignment. However, the great quantity of sequence data requires a high-throughput identification method. Therefore, based o...

  • Article
  • Open Access
6 Citations
3,907 Views
14 Pages

Loss of Lymphotoxin Alpha-Expressing Memory B Cells Correlates with Metastasis of Human Primary Melanoma

  • Franziska Werner,
  • Christine Wagner,
  • Martin Simon,
  • Katharina Glatz,
  • Kirsten D. Mertz,
  • Heinz Läubli,
  • Erika Richtig,
  • Johannes Griss and
  • Stephan N. Wagner

Activated antigen-experienced B cells play an unexpected complex role in anti-tumor immunity in human melanoma patients. However, correlative studies between B cell infiltration and tumor progression are limited by the lack of distinction between fun...

  • Article
  • Open Access
3 Citations
3,388 Views
17 Pages

Complex systems are fully described by the connectedness of their elements studying how these develop a collective behavior, interacting with each other following their inner features, and the structure and dynamics of the entire system. The forthcom...

  • Article
  • Open Access
3 Citations
2,389 Views
20 Pages

Nanoparticle Metrology of Silicates Using Time-Resolved Multiplexed Dye Fluorescence Anisotropy, Small Angle X-ray Scattering, and Molecular Dynamics Simulations

  • Daniel Doveiko,
  • Alan R. G. Martin,
  • Vladislav Vyshemirsky,
  • Simon Stebbing,
  • Karina Kubiak-Ossowska,
  • Olaf Rolinski,
  • David J. S. Birch and
  • Yu Chen

7 April 2024

We investigate the nanometrology of sub-nanometre particle sizes in industrially manufactured sodium silicate liquors at high pH using time-resolved fluorescence anisotropy. Rather than the previous approach of using a single dye label, we investigat...

  • Article
  • Open Access
12 Citations
3,016 Views
24 Pages

17 April 2020

We consider a dynamic lightpath provisioning problem in translucent spectrally–spatially flexible optical networks (SS-FONs) in which flexible signal regeneration is achieved with transponders operating in back-to-back (B2B) configurations. In...

  • Article
  • Open Access
17 Citations
3,351 Views
15 Pages

11 September 2020

We analyze a nonlinear q-voter model with stochastic noise, interpreted in the social context as independence, on a duplex network. The size of the lobby q (i.e., the pressure group) is a crucial parameter that changes the behavior of the system. The...

  • Article
  • Open Access
7 Citations
2,271 Views
22 Pages

7 September 2023

Intermittent bus lanes (IBLs) can alleviate the contradiction between bus priority and the urgent demand of general vehicles for road resources. However, existing IBL strategies seldom pay attention to the setting method of the dynamic bus lanes at i...

  • Article
  • Open Access
1,221 Views
12 Pages

Expanded Performance Comparison of the Oncuria 10-Plex Bladder Cancer Urine Assay Using Three Different Luminex xMAP Instruments

  • Sunao Tanaka,
  • Takuto Shimizu,
  • Ian Pagano,
  • Wayne Hogrefe,
  • Sherry Dunbar,
  • Charles J. Rosser and
  • Hideki Furuya

Background/Objectives: The clinically validated multiplex Oncuria bladder cancer (BC) assay quickly and noninvasively identifies disease risk and tracks treatment success by simultaneously profiling 10 protein biomarkers in voided urine samples. Oncu...

  • Article
  • Open Access
6 Citations
2,281 Views
17 Pages

Synchronization Induced by Layer Mismatch in Multiplex Networks

  • Md Sayeed Anwar,
  • Sarbendu Rakshit,
  • Jürgen Kurths and
  • Dibakar Ghosh

19 July 2023

Heterogeneity among interacting units plays an important role in numerous biological and man-made complex systems. While the impacts of heterogeneity on synchronization, in terms of structural mismatch of the layers in multiplex networks, has been st...

  • Article
  • Open Access
1 Citations
2,988 Views
17 Pages

POL-MUX System for Noncoherent Optical Networks

  • Radim Sifta,
  • Michal Latal,
  • Petr Munster and
  • Tomas Horvath

16 June 2021

This paper is focused on applying a polarization multiplex to passive optical networks to double their transmission bandwidth without significant changes in the distribution network. Although polarization multiplexes are already employed for high-spe...

  • Article
  • Open Access
33 Citations
9,763 Views
10 Pages

Dynamic Sensor Interrogation Using Wavelength-Swept Laser with a Polygon-Scanner-Based Wavelength Filter

  • Yong Seok Kwon,
  • Myeong Ock Ko,
  • Mi Sun Jung,
  • Ik Gon Park,
  • Namje Kim,
  • Sang-Pil Han,
  • Han-Cheol Ryu,
  • Kyung Hyun Park and
  • Min Yong Jeon

29 July 2013

We report a high-speed (~2 kHz) dynamic multiplexed fiber Bragg grating (FBG) sensor interrogation using a wavelength-swept laser (WSL) with a polygon-scanner-based wavelength filter. The scanning frequency of the WSL is 18 kHz, and the 10 dB scann...

  • Article
  • Open Access
2 Citations
3,699 Views
11 Pages

13 December 2022

Several multiplex nucleic acid assay platforms have been developed in response to the increasing importance of nucleic acid analysis, but these assays should be optimized as per the requirements of point-of-care for clinical diagnosis. To achieve rap...

  • Article
  • Open Access
840 Views
19 Pages

18 February 2025

To address the inadequacies of traditional Advanced Orbiting Systems (AOS) multiplexing algorithms in accommodating the networked and diverse transmission demands of space data, this paper proposes an efficient network AOS integrated multiplexing alg...

  • Article
  • Open Access
21 Citations
5,808 Views
9 Pages

Performance Optimization Design for a High-Speed Weak FBG Interrogation System Based on DFB Laser

  • Yiqiang Yao,
  • Zhengying Li,
  • Yiming Wang,
  • Siqi Liu,
  • Yutang Dai,
  • Jianmin Gong and
  • Lixin Wang

22 June 2017

A performance optimization design for a high-speed fiber Bragg grating (FBG) interrogation system based on a high-speed distributed feedback (DFB) swept laser is proposed. A time-division-multiplexing sensor network with identical weak FBGs is consti...

  • Article
  • Open Access
238 Views
10 Pages

Development of a Multiplex Droplet Digital PCR Assay for Detection of Tick-Borne Pathogens

  • Lijuan He,
  • Lin Zhang,
  • Like Duan,
  • Xuexia Hou,
  • Jingwen Li and
  • Qin Hao

13 February 2026

Tick-borne pathogens pose a significant threat to human health. In this study, a multiple droplet digital PCR (ddPCR) assay was developed to detect four tick-borne pathogens: Borrelia burgdorferi sensu lato (Bbsl), Coxiella burnetii (C. burnetii), sp...

  • Article
  • Open Access
1 Citations
752 Views
13 Pages

8 September 2025

Recent research and instances have demonstrated that most real-world systems can be effectively schematized by multiplex networks. Moreover, the interactions within systems often emerge among triadic or tetradic interactions, or even interactions wit...

  • Article
  • Open Access
4 Citations
2,905 Views
14 Pages

2 November 2020

Smart home technologies are growing actively all around the world. As a result, great pressures are imposed on internet of things networks by dynamic traffic and plenty of devices. The passive optical network is considered one of the most promising f...

  • Article
  • Open Access
4 Citations
8,105 Views
13 Pages

1 November 2016

Recently, the emergent dynamics in multiplex networks, composed of layers of multiple networks, has been discussed extensively in network sciences. However, little is still known about whether and how the evolution of strategy for selecting a layer t...

  • Communication
  • Open Access
8 Citations
3,492 Views
13 Pages

Two-photon microscopy enables monitoring cellular dynamics and communication in complex systems, within a genuine environment, such as living tissues and, even, living organisms. Particularly, its application to understand cellular interactions in th...

  • Article
  • Open Access
4 Citations
4,551 Views
11 Pages

Response Surface Methodology for Optimization of Multiplex-PCR Protocols for Detection of TYLCV, TSWV and Fol Molecular Markers: Analytical Performance Evaluation

  • Richecarde Lafrance,
  • José Benigno Valdez-Torres,
  • Claudia Villicaña,
  • Raymundo Saúl García-Estrada,
  • Mayra Janeth Esparza-Araiza and
  • Josefina León-Félix

28 January 2023

Molecular markers linked to disease resistance genes which affect economically important crops are of great interest. In the case of tomato, a major focus on resistance breeding to multiple fungal and viral pathogens such as Tomato yellow leaf curl v...

  • Article
  • Open Access
2 Citations
3,228 Views
18 Pages

Reconstructing Sparse Multiplex Networks with Application to Covert Networks

  • Jin-Zhu Yu,
  • Mincheng Wu,
  • Gisela Bichler,
  • Felipe Aros-Vera and
  • Jianxi Gao

10 January 2023

Network structure provides critical information for understanding the dynamic behavior of complex systems. However, the complete structure of real-world networks is often unavailable, thus it is crucially important to develop approaches to infer a mo...

  • Review
  • Open Access
13 Citations
6,752 Views
16 Pages

Metasurface Holography with Multiplexing and Reconfigurability

  • Yijun Zou,
  • Hui Jin,
  • Rongrong Zhu and
  • Ting Zhang

26 December 2023

Metasurface holography offers significant advantages, including a broad field of view, minimal noise, and high imaging quality, making it valuable across various optical domains such as 3D displays, VR, and color displays. However, most passive pure-...

  • Feature Paper
  • Review
  • Open Access
42 Citations
12,075 Views
30 Pages

Multiplex Tissue Imaging: Spatial Revelations in the Tumor Microenvironment

  • Stephanie van Dam,
  • Matthijs J. D. Baars and
  • Yvonne Vercoulen

28 June 2022

The tumor microenvironment is a complex ecosystem containing various cell types, such as immune cells, fibroblasts, and endothelial cells, which interact with the tumor cells. In recent decades, the cancer research field has gained insight into the c...

  • Article
  • Open Access
1 Citations
1,876 Views
15 Pages

Multiplexed Digital PCR Reference Gene Measurement for Genomic and Cell-Free DNA Analysis

  • Dilek Yener,
  • Eloise J. Busby,
  • Jo Vandesompele,
  • Gertjan Wils,
  • Susan D. Richman,
  • Henry M. Wood,
  • Jim F. Huggett,
  • Carole A. Foy and
  • Alison S. Devonshire

3 October 2025

Precision medicine approaches rely on accurate somatic variant detection, where the DNA input into genomic workflows is a key variable. However, there are no gold standard methods for total DNA quantification. In this study, a pentaplex reference gen...

  • Article
  • Open Access
1 Citations
2,725 Views
13 Pages

A 10-Bit 400 MS/s Dual-Channel Time-Interleaved SAR ADC Based on Comparator Multiplexing

  • Cheng Wang,
  • Zhanpeng Yang,
  • Xinpeng Xing,
  • Quanzhen Duan,
  • Xinfa Zheng and
  • Georges Gielen

27 September 2023

This paper proposes a 10-bit 400 MS/s dual-channel time-interleaved (TI) successive approximation register (SAR) analog-to-digital converter (ADC) immune to offset mismatch between channels. A novel comparator multiplexing structure is proposed in ou...

  • Article
  • Open Access
250 Views
11 Pages

Tunable Wavelength-Multiplexed Dual-Frequency Bound Pulse in a Carbon-Nanotube-Based Fiber Laser

  • Lin Wang,
  • Guoqing Hu,
  • Yan Wang,
  • Guangwei Chen,
  • Liang Xuan,
  • Zhehai Zhou and
  • Jun Yu

20 January 2026

We experimentally and theoretically demonstrate coexistence of three different wavelength-multiplexed bound dual-frequency pulses in an all-fiber mode-locked fiber laser, effectively achieved by exploiting polarization-dependent loss effects and two...

  • Article
  • Open Access
4,639 Views
11 Pages

Three-Level De-Multiplexed Dual-Branch Complex Delta-Sigma Transmitter

  • Anis Ben Arfi,
  • Fahmi Elsayed,
  • Pouya M. Aflaki,
  • Brad Morris and
  • Fadhel M. Ghannouchi

20 February 2018

In this paper, a dual-branch topology driven by a Delta-Sigma Modulator (DSM) with a complex quantizer, also known as the Complex Delta Sigma Modulator (CxDSM), with a 3-level quantized output signal is proposed. By de-multiplexing the 3-level Delta-...

  • Article
  • Open Access
12 Citations
4,828 Views
10 Pages

Simultaneous Detection of Drug-Induced Liver Injury Protein and microRNA Biomarkers Using Dynamic Chemical Labelling on a Luminex MAGPIX System

  • Antonio Marín-Romero,
  • Mavys Tabraue-Chávez,
  • Bárbara López-Longarela,
  • Mario A. Fara,
  • Rosario M. Sánchez-Martín,
  • James W. Dear,
  • Hugh Ilyine,
  • Juan J. Díaz-Mochón and
  • Salvatore Pernagallo

3 October 2021

Drug-induced liver injury (DILI) is a potentially fatal adverse event and a leading cause for pre- and post-marketing drug withdrawal. Several multinational DILI initiatives have now recommended a panel of protein and microRNA (miRNA) biomarkers that...

  • Review
  • Open Access
23 Citations
7,023 Views
28 Pages

20 March 2019

This paper provides a technical review regarding the latest progress on multi-input multi-output (MIMO) digital signal processing (DSP) equalization techniques for high-capacity fiber-optic communication networks. Space division multiplexing (SDM) te...

  • Article
  • Open Access
2,040 Views
15 Pages

Interactive Learning of a Dual Convolution Neural Network for Multi-Modal Action Recognition

  • Qingxia Li,
  • Dali Gao,
  • Qieshi Zhang,
  • Wenhong Wei and
  • Ziliang Ren

22 October 2022

RGB and depth modalities contain more abundant and interactive information, and convolutional neural networks (ConvNets) based on multi-modal data have achieved successful progress in action recognition. Due to the limitation of a single stream, it i...

  • Review
  • Open Access
19 Citations
4,608 Views
26 Pages

Recent Advances in Surface Plasmon Resonance (SPR) Technology for Detecting Ovarian Cancer Biomarkers

  • Vikneswary Ravi Kumar,
  • Nirmala Chandralega Kampan,
  • Nor Haslinda Abd Aziz,
  • Chew Kah Teik,
  • Mohamad Nasir Shafiee and
  • P. Susthitha Menon

27 November 2023

Epithelial Ovarian Cancer (EOC) is a leading cause of cancer-related deaths among women, mainly due to a lack of early detection and screening methods. Advanced immunoassay techniques, such as Luminex and proximity extension assay (PEA) technology, s...

  • Review
  • Open Access
25 Citations
6,378 Views
23 Pages

Precision cancer medicine necessitates a personalized treatment plan for each individual patient. Given cancer’s heterogeneity and dynamic nature, the plot of patient-specific signatures composed of multiple cancer circulating biomarkers is use...

  • Article
  • Open Access
1 Citations
3,574 Views
24 Pages

27 November 2024

This study presents a synthesizer topology based on a delay-locked loop (DLL) and programmable frequency multiplier for 5G+ communication systems. The proposed synthesizer comprises a 512-phase DLL, an intermediate frequency generator (IFG), and an R...

  • Article
  • Open Access
1 Citations
3,163 Views
14 Pages

Sensitive and Specific Analyses of Colorectal Cancer Recurrence through Multiplex superRCA Mutation Detection in Blood Plasma

  • Emma Sandberg,
  • Luís Nunes,
  • Per-Henrik Edqvist,
  • Lucy Mathot,
  • Lei Chen,
  • Tomas Edgren,
  • Shahed Al Nassralla,
  • Bengt Glimelius,
  • Ulf Landegren and
  • Tobias Sjöblom

27 January 2024

Mutation analysis of circulating tumor DNA (ctDNA) has applications in monitoring of colorectal cancer (CRC) patients for recurrence. Considering the low tumor fraction of ctDNA in cell-free DNA (cfDNA) isolated from blood plasma, the sensitivity of...

  • Article
  • Open Access
6 Citations
6,670 Views
22 Pages

MultiSero: An Open-Source Multiplex-ELISA Platform for Measuring Antibody Responses to Infection

  • Janie R. Byrum,
  • Eric Waltari,
  • Owen Janson,
  • Syuan-Ming Guo,
  • Jenny Folkesson,
  • Bryant B. Chhun,
  • Joanna Vinden,
  • Ivan E. Ivanov,
  • Marcus L. Forst and
  • John E. Pak
  • + 17 authors

A multiplexed enzyme-linked immunosorbent assay (ELISA) that simultaneously measures antibody binding to multiple antigens can extend the impact of serosurveillance studies, particularly if the assay approaches the simplicity, robustness, and accurac...

  • Article
  • Open Access
9 Citations
4,664 Views
13 Pages

FPGA-Based Dynamic Wavelength Interrogation System for Thousands of Identical FBG Sensors

  • Jiaqi Wang,
  • Xuelei Fu,
  • Hui Gao,
  • Xin Gui,
  • Honghai Wang and
  • Zhengying Li

29 January 2022

Under realistic scenarios, more fiber Bragg gratings (FBGs) are always expected to be multiplexed in one sensor array to share the expensive optical components and electrical devices. However, either the sensing number or the interrogation frequency...

  • Article
  • Open Access
3 Citations
2,486 Views
23 Pages

26 May 2022

It has become a hot issue to integrate the carbon market, energy market, and financial market into one system and explore the relationship among them. Considering that the carbon market, energy market, and financial market all have chaotic characteri...

  • Article
  • Open Access
3 Citations
2,373 Views
17 Pages

16 January 2022

This study focuses on the finite-time set reachability of probabilistic Boolean multiplex control networks (PBMCNs). Firstly, based on the state transfer graph (STG) reconstruction technique, the PBMCNs are extended to random logic dynamical systems....

  • Review
  • Open Access
96 Citations
17,751 Views
17 Pages

20 July 2015

Over the last decade, the growing need in disease diagnostics has stimulated rapid development of new technologies with unprecedented capabilities. Recent emerging infectious diseases and epidemics have revealed the shortcomings of existing diagnosti...

  • Article
  • Open Access
81 Citations
10,909 Views
17 Pages

14 November 2014

We present a tunable diode laser spectrometer with a novel, rapid time multiplexed direct absorption- and wavelength modulation-spectroscopy operation mode. The new technique allows enhancing the precision and dynamic range of a tunable diode laser a...

  • Article
  • Open Access
6 Citations
3,015 Views
13 Pages

Multiplexed CRISPR Assay for Amplification-Free Detection of miRNAs

  • P. I. Thilini De Silva,
  • Keshani Hiniduma,
  • Rachelle Canete,
  • Ketki S. Bhalerao,
  • Sherif M. Shawky,
  • Hansana Gunathilaka,
  • Jessica L. Rouge,
  • Islam M. Mosa,
  • David C. Steffens and
  • James F. Rusling
  • + 2 authors

29 May 2025

CRISPR-Cas proteins from bacteria are powerful tools for gene editing and molecular diagnostics. Expanding capacity of CRISPR to low cost, multiplexed assays of biomarkers is a key to future disease diagnostics, since multiple biomarker detection is...

  • Article
  • Open Access
1 Citations
598 Views
14 Pages

24 October 2025

Three-dimensional holographic imaging technology is increasingly applied in biomedical detection, materials science, and industrial non-destructive testing. Achieving high-resolution, large-field-of-view, and high-speed three-dimensional imaging has...

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