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  • Article
  • Open Access
1,204 Views
14 Pages

Characterization and Comparison of Lipids in Yak Colostrum, Buffalo Colostrum, and Cow Colostrum Based on UHPLC-QTOF-MS Lipidomics

  • Ruohan Li,
  • Yuzhuo Wang,
  • Changhui Li,
  • Jiaxiang Huang,
  • Qingkun Zeng,
  • Ling Li,
  • Pan Yang,
  • Pengjie Wang,
  • Min Chu and
  • Hao Zhang
  • + 2 authors

27 March 2025

Colostrum is a nutrient-dense food rich in proteins, immune modulators, and growth factors essential for neonatal development. Its lipids serve as a key energy source and facilitate cellular functions. While yak colostrum (YC) and buffalo colostrum (...

  • Feature Paper
  • Article
  • Open Access
2 Citations
4,096 Views
10 Pages

Evaluation of Colostrum Components and Milking Status Affecting Colostrum IgG Concentration

  • Shuji Kayasaki,
  • Hitomi Satoh,
  • Keitaro Oguchi,
  • Kyoko Chisato,
  • Rika Fukumori and
  • Shin Oikawa

3 March 2025

This study investigated IgG concentrations, bacterial contamination, and nutrient components of colostrum on dairy farms in eastern Hokkaido, Japan, to examine the factors making it possible to obtain high-quality colostrum. Colostrum samples were co...

  • Article
  • Open Access
8 Citations
1,409 Views
15 Pages

Colostrum-Derived Melatonin Plus PEG Microspheres Modulate the Oxidative Metabolism of Human Colostrum Phagocytes

  • Caroline G. Silva,
  • Viviane F. Luz,
  • Victor L. Nunes,
  • Ana B. M. Verzoto,
  • Aron C. de M. Cotrim,
  • Wagner B. dos Santos,
  • Eduardo L. França and
  • Adenilda C. Honorio-França

16 January 2025

Background/Objectives: Exogenous melatonin adsorbed onto PEG microspheres can modulate the functional activity of phagocytes in colostrum, but no data are available on the activity of melatonin found in colostrum. Therefore, the objective of this stu...

  • Review
  • Open Access
13 Citations
8,310 Views
15 Pages

Colostrum Composition, Characteristics and Management for Buffalo Calves: A Review

  • Daria Lotito,
  • Eleonora Pacifico,
  • Sara Matuozzo,
  • Nadia Musco,
  • Piera Iommelli,
  • Fabio Zicarelli,
  • Raffaella Tudisco,
  • Federico Infascelli and
  • Pietro Lombardi

In this review, the composition, characteristics, and management of dairy buffalo calves were examined and compared with bovines. The neonatal period is critical for buffalo calves and is characterized by a high mortality rate (more than 40%). The ea...

  • Review
  • Open Access
558 Citations
45,895 Views
33 Pages

14 April 2011

Immunoglobulins form an important component of the immunological activity found in milk and colostrum. They are central to the immunological link that occurs when the mother transfers passive immunity to the offspring. The mechanism of transfer varie...

  • Article
  • Open Access
8 Citations
3,784 Views
14 Pages

The Influence of Feeding with Colostrum and Colostrum Replacer on Major Blood Biomarkers and Growth Performance in Dairy Calves

  • Ramune Grigaleviciute,
  • Rita Planciuniene,
  • Ieva Prikockyte,
  • Eivina Radzeviciute-Valciuke,
  • Austeja Baleviciute,
  • Augustinas Zelvys,
  • Aukse Zinkeviciene,
  • Vilma Zigmantaite,
  • Audrius Kucinskas and
  • Povilas Kavaliauskas
  • + 1 author

7 February 2023

Bovine colostrum (BC) is the first milk produced by lactating cows after parturition. BC is rich in various amino acids, proteins, and fats essential for the nutrition of the neonate calves. Despite the evident beneficial effect of BC on calves, the...

  • Review
  • Open Access
24 Citations
20,971 Views
15 Pages

Nutritional Parameters in Colostrum of Different Mammalian Species

  • Paolo Polidori,
  • Roberta Rapaccetti,
  • Yulia Klimanova,
  • Jing-Jing Zhang,
  • Giuseppe Santini and
  • Silvia Vincenzetti

5 September 2022

Colostrum (or first milk) is the food produced by all the mothers in all specific mammalian species, ruminants, monogastric and marine mammalians for their newborns during the first 24–48 h post-partum. Colostrum provides to the neonate all ess...

  • Article
  • Open Access
3 Citations
2,933 Views
11 Pages

Grossly Bloody Colostrum—The Need for Staff Education and Maternal Support

  • Katarzyna Wszołek,
  • Stanisław Przewoźny,
  • Adrianna Nowek,
  • Angelika Odor,
  • Paulina Małyszka (Hoffmann),
  • Marcin Przybylski,
  • Jakub Żurawski,
  • Małgorzata Pięt and
  • Maciej Wilczak

26 November 2023

Background: Grossly bloody colostrum is defined as the presence of brownish or bloody-colored colostrum. The frequency is determined to be 0.1% of all births, and no predisposing factor for its occurrence was determined. The purpose of this study was...

  • Review
  • Open Access
42 Citations
10,084 Views
28 Pages

Antimicrobial Properties of Colostrum and Milk

  • Furkan Eker,
  • Emir Akdaşçi,
  • Hatice Duman,
  • Yalçın Mert Yalçıntaş,
  • Ahmet Alperen Canbolat,
  • Arda Erkan Kalkan,
  • Sercan Karav and
  • Dunja Šamec

The growing number of antibiotic resistance genes is putting a strain on the ecosystem and harming human health. In addition, consumers have developed a cautious attitude towards chemical preservatives. Colostrum and milk are excellent sources of ant...

  • Review
  • Open Access
15 Citations
15,060 Views
20 Pages

A Review: The Effect of Bovine Colostrum on Immunity in People of All Ages

  • Hao Duan,
  • Qian Sun,
  • Chao Chen,
  • Rongchang Wang and
  • Wenjie Yan

25 June 2024

Bovine colostrum provides newborn calves with strong passive immunity, which will further affect the immunity of their offspring. Compared with other commercial dairy products, bovine colostrum emphasizes the limit of aflatoxin M1, pathogenic bacteri...

  • Review
  • Open Access
18 Citations
11,362 Views
15 Pages

Revealing the Potency of Growth Factors in Bovine Colostrum

  • Yalçın Mert Yalçıntaş,
  • Hatice Duman,
  • Jose M. Miranda López,
  • Alicia C. Mondragón Portocarrero,
  • Mauro Lombardo,
  • Farid Khallouki,
  • Wojciech Koch,
  • Matteo Bordiga,
  • Hesham El-Seedi and
  • Sercan Karav
  • + 2 authors

21 July 2024

Colostrum is a nutritious milk synthesized by mammals during the postpartum period, and its rich bioactive components has led to a global increase in the consumption of bovine colostrum as a supplement. Bovine colostrum contains key components such a...

  • Article
  • Open Access
5 Citations
4,262 Views
12 Pages

Comparative Analysis of Maternal Colostrum and Colostrum Replacer Effects on Immunity, Growth, and Health of Japanese Black Calves

  • Marimu Urakawa,
  • Mahmoud Baakhtari,
  • Amany Ramah,
  • Shoichiro Imatake,
  • Parnian Ahmadi,
  • Yuichiro Deguchi,
  • Mizuho Uematsu,
  • Yoshiki Nakama,
  • Kazunari Imabeppu and
  • Masahiro Yasuda
  • + 1 author

22 January 2024

Maternal colostrum (MC) is an important source of nutrients and immune factors for newborn calves. However, when colostrum is unavailable or of poor quality, a colostrum replacer (CR) may be a suitable alternative to MC. As stock-raising farmers must...

  • Article
  • Open Access
5 Citations
2,156 Views
14 Pages

Comparison of the Fatty Acid Profiles of Sow and Goat Colostrum

  • Lucía Ayala,
  • Pilar Gómez-Cortés,
  • Fuensanta Hernández,
  • Josefa Madrid,
  • Silvia Martínez-Miró and
  • Miguel Angel de la Fuente

29 July 2024

Currently, the utilization of hyperprolific sows has stimulated the search for supplements aimed at enhancing piglet survival, as these sows yield more offspring than they can adequately feed with their colostrum production. In contrast, intensive go...

  • Feature Paper
  • Review
  • Open Access
36 Citations
24,440 Views
14 Pages

7 June 2021

There is increasing awareness that a broad range of gastrointestinal diseases, and some systemic diseases, are characterized by failure of the mucosal barrier. Bovine colostrum is a complex biological fluid replete with growth factors, nutrients, hor...

  • Article
  • Open Access
5 Citations
3,316 Views
13 Pages

Breastfeeding-Related Practices in Rural Ethiopia: Colostrum Avoidance

  • M. Ascensión Olcina Simón,
  • Rosita Rotella,
  • Jose M. Soriano,
  • Agustin Llopis-Gonzalez,
  • Isabel Peraita-Costa and
  • María Morales-Suarez-Varela

3 May 2023

The practices of colostrum avoidance and prelacteal feeding, which are common in many developing countries, including Ethiopia, are firmly rooted in ancient traditions. The main objective of this work is to identify the prevalence of colostrum avoida...

  • Article
  • Open Access
4 Citations
3,476 Views
21 Pages

Biologically Active Sheep Colostrum for Topical Treatment and Skin Care

  • Kinga Kazimierska,
  • Ilona Szabłowska-Gadomska,
  • Stefan Rudziński,
  • Katarzyna Kośla,
  • Elżbieta Płuciennik,
  • Łukasz Bobak,
  • Aleksandra Zambrowicz and
  • Urszula Kalinowska-Lis

Colostrum is gaining popularity in cosmetic products. The present study compared the composition and selected biological properties of colostrum from Polish sheep (colostrum 1) and Swiss sheep (colostrum 2), particularly those that can affect healthy...

  • Article
  • Open Access
4 Citations
3,048 Views
10 Pages

Transfer of Mycotoxins from Lactation Feed to Colostrum of Sows

  • Paolo Trevisi,
  • Diana Luise,
  • Elisa Spinelli,
  • Federico Correa,
  • Elena De Leo,
  • Giovanna Trambajolo,
  • Giuseppe Diegoli and
  • Paolo Bosi

30 November 2020

Studies regarding the transfer of mycotoxins from sow feed to colostrum are scarce. A sample of in-house produced lactation feed and one of colostrum were collected from two or three sows per farm (total 49) from 19 farms. The feed contents of aflato...

  • Article
  • Open Access
13 Citations
6,972 Views
9 Pages

Fermentation Ability of Bovine Colostrum by Different Probiotic Strains

  • Ivana Hyrslova,
  • Gabriela Krausova,
  • Tereza Michlova,
  • Antonin Kana and
  • Ladislav Curda

Over the past decade, the use of bovine colostrum and its bioactive components as the basis of functional food and dietary supplements for humans has substantially increased. However, for developing new products enriched with probiotics and bovine co...

  • Article
  • Open Access
4 Citations
2,611 Views
12 Pages

Chemometric Approaches to Analyse the Composition of a Ewe’s Colostrum

  • Massimo Todaro,
  • Giuseppe Maniaci,
  • Riccardo Gannuscio,
  • Daniela Pampinella and
  • Maria Luisa Scatassa

8 March 2023

Colostrum is a major source of immunity in lambs and, in general, in all newborn ruminants. It allows the transfer of antibodies from the ewe to the lamb, and it becomes the exclusive source of nutrients for a newborn. Among the most significant Pear...

  • Article
  • Open Access
885 Views
28 Pages

The Microbial Composition of Bovine Colostrum as Influenced by Antibiotic Treatment

  • Ruth Conboy-Stephenson,
  • Dhrati Patangia,
  • Kevin Linehan,
  • R. Paul Ross and
  • Catherine Stanton

3 December 2025

Background/Objectives: Bovine colostrum, the initial milk produced by cows postpartum, contains an array of key nutritional, immune, and microbial components that support the calf’s physiological development, immune maturation, and intestinal c...

  • Article
  • Open Access
16 Citations
2,755 Views
20 Pages

The Study of Yak Colostrum Nutritional Content Based on Foodomics

  • Lin Xiong,
  • Jie Pei,
  • Pengjia Bao,
  • Xingdong Wang,
  • Shaoke Guo,
  • Mengli Cao,
  • Yandong Kang,
  • Ping Yan and
  • Xian Guo

19 April 2023

The utilization of yak milk is still in a primary stage, and the nutrition composition of yak colostrum is not systematically characterized at present. In this study, the lipids, fatty acids, amino acids and their derivatives, metabolites in yak colo...

  • Review
  • Open Access
33 Citations
10,079 Views
17 Pages

Nutritional and Functional Properties of Colostrum in Puppies and Kittens

  • Luciana Rossi,
  • Ana Elena Valdez Lumbreras,
  • Simona Vagni,
  • Matteo Dell’Anno and
  • Valentino Bontempo

15 November 2021

The present review aims toward a better understanding of the nutrition of newborn puppies and kittens. The post-natal period is very sensitive in dogs and cats, as in other animal species. During the first two weeks of life, puppies and kittens are a...

  • Article
  • Open Access
19 Citations
3,754 Views
11 Pages

Melatonin Action on the Activity of Phagocytes from the Colostrum of Obese Women

  • Tassiane C. Morais,
  • Adenilda C. Honorio-França,
  • Mahmi Fujimori,
  • Ocilma B. de Quental,
  • Rafael S. Pessoa,
  • Eduardo L. França and
  • Luiz C. de Abreu

23 September 2019

Background and objectives: Breastfeeding promotion is an important public health strategy for counter-balancing the negative effects of maternal overweight and obesity. Colostrum contains melatonin, which can attenuate the impacts of excessive matern...

  • Article
  • Open Access
18 Citations
4,106 Views
14 Pages

Relationship between the Quality of Colostrum and the Formation of Microflora in the Digestive Tract of Calves

  • Kamila Puppel,
  • Marcin Gołębiewski,
  • Katarzyna Konopka,
  • Małgorzata Kunowska-Slósarz,
  • Jan Slósarz,
  • Grzegorz Grodkowski,
  • Tomasz Przysucha,
  • Marek Balcerak,
  • Beata Madras-Majewska and
  • Tomasz Sakowski

29 July 2020

The aim of the study was to determine the relationship between the quality of colostrum and the formation of intestinal bacterial microflora in calves from birth to day 7. Seventy-five multiparous Polish Holstein–Friesian cows were selected. Co...

  • Article
  • Open Access
8 Citations
3,075 Views
11 Pages

Relation between Color and Chemical Composition of Dromedary Camel Colostrum

  • Halima El-Hatmi,
  • Olfa Oussaief,
  • Imen Hammadi,
  • Mohamed Dbara,
  • Mohamed Hammadi,
  • Touhami Khorchani and
  • Zeineb Jrad

28 January 2023

Camel milk industrialization faces technological problems related to the presence of colostrum in milk. The determination of color parameters may serve to differentiate between colostrum and milk. This work aimed to study the relationship between the...

  • Review
  • Open Access
2 Citations
5,691 Views
15 Pages

Exploring the Therapeutic Potential of Bovine Colostrum for Cancer Therapies

  • Yalçın Mert Yalçıntaş,
  • Mikhael Bechelany and
  • Sercan Karav

17 August 2025

Colostrum is a nutrient-rich fluid secreted by mammals shortly after birth, primarily to provide passive immunity and support early immune development in newborns. Among its various sources, bovine colostrum is the most widely used supplement due to...

  • Review
  • Open Access
3 Citations
9,770 Views
14 Pages

11 January 2025

Colostrum, the first fluid secreted by the mammary glands of mammalian mothers, contains essential nutrients for the health and survival of newborns. Bovine colostrum (BC) is notable for its high concentrations of bioactive components, such as immuno...

  • Article
  • Open Access
5 Citations
3,002 Views
16 Pages

Bioactive Peptides in Greek Goat Colostrum: Relevance to Human Metabolism

  • Maria Louiza Petre,
  • Anna Nefeli Kontouli Pertesi,
  • Olympia Eirini Boulioglou,
  • Eleana Sarantidi,
  • Artemis G. Korovesi,
  • Athina Kozei,
  • Angeliki I. Katsafadou,
  • George T. Tsangaris,
  • Antonia Trichopoulou and
  • Athanasios K. Anagnostopoulos

6 December 2024

Colostrum is essential for the survival and development of newborn mammals. This primary source of nourishment during the first days of infant life is rich in functional components conductive to the enhancement of neonate immunity and growth. Compare...

  • Review
  • Open Access
37 Citations
13,555 Views
29 Pages

18 December 2021

The immunoglobulin concentration in bovine colostrum should be measured to ensure feeding with sufficient immunoglobulins (≥50 mg immunoglobulin G mL−1). Adequate feeding prevents diseases, promotes development, and has a positive influence...

  • Article
  • Open Access
10 Citations
3,790 Views
14 Pages

Leptin, Adiponectin, and Melatonin Modulate Colostrum Lymphocytes in Mothers with Obesity

  • Gabrielle do Amaral Virginio Pereira,
  • Tassiane Cristina Morais,
  • Eduardo Luzia França,
  • Blanca Elena Guerrero Daboin,
  • Italla Maria Pinheiro Bezerra,
  • Rafael Souza Pessoa,
  • Ocilma Barros de Quental,
  • Adenilda Cristina Honório-França and
  • Luiz Carlos de Abreu

31 January 2023

Pregnancy complicated by obesity is associated with adverse triggered gestational and neonatal outcomes, with reductions in the subtypes of CD4+ T-lymphocytes representing the modulators of inflammation. It needs to be better established how maternal...

  • Article
  • Open Access
19 Citations
5,928 Views
13 Pages

Levels of Growth Factors and IgA in the Colostrum of Women from Burundi and Italy

  • Daniel Munblit,
  • Priya Abrol,
  • Shreya Sheth,
  • Li Yan Chow,
  • Ekaterina Khaleva,
  • Alan Asmanov,
  • Silvana Lauriola,
  • Ezio M. Padovani,
  • Pasquale Comberiati and
  • Diego G. Peroni
  • + 3 authors

3 September 2018

Colostrum is produced in the first days postpartum. It is a known source of immune mediators for a newborn within the first week of life. Although it is still unclear if colostrum composition varies between populations, recent data suggest difference...

  • Article
  • Open Access
35 Citations
8,224 Views
14 Pages

Evaluation of Factors Affecting Colostrum Quality and Quantity in Holstein Dairy Cattle

  • Aikaterini Soufleri,
  • Georgios Banos,
  • Nikolaos Panousis,
  • Dimitrios Fletouris,
  • Georgios Arsenos,
  • Alexandros Kougioumtzis and
  • Georgios E. Valergakis

5 July 2021

The objective of this study was to conduct a large-scale investigation of colostrum composition and yield and an evaluation of factors affecting them. In this study, 1017 clinically healthy Holstein cows from 10 farms were used. The colostrum TS were...

  • Review
  • Open Access
5 Citations
16,763 Views
16 Pages

The Potential Applications of Natural Colostrum in Skin Health

  • Ecem Bolat,
  • Zeynep Karagöz,
  • José Luiz de Brito Alves,
  • José Patrocínio Ribeiro Cruz Neto,
  • Anna Maria Witkowska,
  • Hesham El-Seedi,
  • Mauro Lombardo and
  • Sercan Karav

20 November 2024

Skin is a crucial organ for preserving the body’s equilibrium. Like other parts of the body, skin also ages due to extrinsic and intrinsic factors, leading to several signs such as wrinkles, spots, and a decline in elasticity, causing a range o...

  • Article
  • Open Access
6 Citations
13,539 Views
17 Pages

Long-Term Bovine Colostrum Supplementation in Football Players

  • Mirosława Cieślicka,
  • Błażej Stankiewicz,
  • Radosław Muszkieta,
  • Małgorzata Tafil-Klawe,
  • Jacek Klawe,
  • Anna Skarpańska-Stejnborn and
  • Joanna Ostapiuk-Karolczuk

14 November 2023

Physical exercise, especially of high intensity, is a significant burden on an athlete’s body. It should be emphasized that achieving high results in competitive sports requires the use of significant, sometimes extreme, exercise loads during t...

  • Article
  • Open Access
5 Citations
3,199 Views
12 Pages

Suitability of Goat Colostrum to Produce a Fermented Yogurt-Type Product

  • Emilio José González-Navarro,
  • María Carmen Beltrán,
  • María Pilar Molina,
  • Francisco Javier Pérez-Barbería,
  • Ana Molina and
  • María Isabel Berruga

3 November 2022

The aim of this study was to investigate the potential use of goat colostrum to produce a yogurt-type product as a novel functional dairy food. Four batches of fermented goat colostrum (GCY) were produced using fermented goat milk (GMY) as a referenc...

  • Article
  • Open Access
34 Citations
4,105 Views
15 Pages

Compositional and Functional Comparisons of the Microbiota in the Colostrum and Mature Milk of Dairy Goats

  • Zhannur Niyazbekova,
  • Xiao-Ting Yao,
  • Ming-Jie Liu,
  • Nomin Bold,
  • Juan-Zhen Tong,
  • Jian-Jun Chang,
  • Ying Wen,
  • Li Li,
  • Yong Wang and
  • Wen-Tao Ma
  • + 1 author

23 October 2020

Goat milk is essential for the initial development of kids by providing a great source of commensal bacteria. In this study, we analyzed the microbiota of the milk of 30 healthy Saanen dairy goats. The 30 samples comprised 15 colostrum and 15 mature...

  • Article
  • Open Access
152 Citations
16,465 Views
14 Pages

Composition and Factors Affecting Quality of Bovine Colostrum: A Review

  • Kamila Puppel,
  • Marcin Gołębiewski,
  • Grzegorz Grodkowski,
  • Jan Slósarz,
  • Małgorzata Kunowska-Slósarz,
  • Paweł Solarczyk,
  • Monika Łukasiewicz,
  • Marek Balcerak and
  • Tomasz Przysucha

2 December 2019

Colostrum as a secretion of the mammary gland is produced and accumulated in the final stage of pregnancy and in the first days after calving. It is designed to provide the calf with the necessary nutrients and biologically active ingredients. One of...

  • Article
  • Open Access
14 Citations
3,451 Views
14 Pages

Essential and Toxic Mineral Content and Fatty Acid Profile of Colostrum in Dairy Sheep

  • Maria Francesca Guiso,
  • Gianni Battacone,
  • Linda Canu,
  • Mario Deroma,
  • Ilaria Langasco,
  • Gavino Sanna,
  • Eleni Tsiplakou,
  • Giuseppe Pulina and
  • Anna Nudda

11 October 2022

Colostrum is a major source of immunity in ruminants. It allows the transfer of antibodies from the mother to the fetus, and it is the exclusive source of nutrients for the newborn. The objectives of this study were (i) to characterize the macro and...

  • Feature Paper
  • Article
  • Open Access
3,521 Views
13 Pages

Influence of Dry Period Length of Swedish Dairy Cows on the Proteome of Colostrum

  • Ruben de Vries,
  • Sjef Boeren,
  • Kjell Holtenius,
  • Jacques Vervoort,
  • Helena Lindmark-Månsson and
  • Kasper Hettinga

11 December 2020

The aim of this study was to evaluate the influence of applying a 4-week instead of an 8-week dry period to dairy cows on the proteome of colostrum (first sample) and of transition milk (the fifth postpartum milk sample). Individual milk serum sample...

  • Article
  • Open Access
7 Citations
3,544 Views
14 Pages

The Effect of Parity on the Quality of Colostrum of Holstein Dairy Cows in the Organic Production System

  • Kinga Grodkowska,
  • Marcin Gołębiewski,
  • Jan Slósarz,
  • Grzegorz Grodkowski,
  • Piotr Kostusiak,
  • Tomasz Sakowski,
  • Marija Klopčič and
  • Kamila Puppel

3 February 2023

A special feature of organic production systems is the cows’ significantly lower productivity, which is adapted to environmental conditions. The quantity and quality of colostrum is negatively correlated, high amounts of colostrum are associate...

  • Article
  • Open Access
8 Citations
4,352 Views
10 Pages

Colostrum Quality Assessment in Dairy Goats: Use of an On-Farm Optical Refractometer

  • Carlos C. Pérez-Marín,
  • David Cano,
  • Francisco A. Arrebola,
  • Valerii H. Petrusha,
  • Pavlo M. Skliarov,
  • José A. Entrenas and
  • Dolores C. Pérez-Marín

20 April 2023

Failure of passive immunity transfer is one of the main causes of increased susceptibility to infectious agents in newborn kids. To ensure successful transfer of passive immunity, kids need to be fed high-quality colostrum, containing an adequate con...

  • Article
  • Open Access
2 Citations
1,711 Views
18 Pages

Untargeted Metabolomics Reveals Key Differences Between Yak, Buffalo, and Cow Colostrum Based on UHPLC-ESI-MS/MS

  • Yuzhuo Wang,
  • Changhui Li,
  • Jiaxiang Huang,
  • Qingkun Zeng,
  • Ling Li,
  • Pan Yang,
  • Pengjie Wang,
  • Min Chu,
  • Jie Luo and
  • Hao Zhang
  • + 1 author

13 January 2025

Background: Colostrum, abundant in immunoglobulins and growth factors, plays a vital role in supporting immunity. Both yak and buffalo milk are characterized by their high protein and fat content. However, the metabolomic profiles of yak colostrum (Y...

  • Article
  • Open Access
21 Citations
3,916 Views
22 Pages

Extracellular Vesicles in Human Preterm Colostrum Inhibit Infection by Human Cytomegalovirus In Vitro

  • Manuela Donalisio,
  • Simona Cirrincione,
  • Massimo Rittà,
  • Cristina Lamberti,
  • Andrea Civra,
  • Rachele Francese,
  • Paola Tonetto,
  • Stefano Sottemano,
  • Marcello Manfredi and
  • David Lembo
  • + 7 authors

Breast milk is a complex biofluid that nourishes infants, supports their growth and protects them from diseases. However, at the same time, breastfeeding is a transmission route for human cytomegalovirus (HCMV), with preterm infants being at a great...

  • Article
  • Open Access
9 Citations
2,373 Views
15 Pages

Polarization of Melatonin-Modulated Colostrum Macrophages in the Presence of Breast Tumor Cell Lines

  • Kenia Maria Rezende Silva,
  • Danielle Cristina Honório França,
  • Adriele Ataídes de Queiroz,
  • Danny Laura Gomes Fagundes-Triches,
  • Patrícia Gelli Feres de Marchi,
  • Tassiane Cristina Morais,
  • Adenilda Cristina Honorio-França and
  • Eduardo Luzía França

3 August 2023

Human colostrum and milk contain diverse cells and soluble components that have the potential to act against tumors. In breast cancer, macrophages play a significant role in immune infiltration and contribute to the progression and spread of tumors....

  • Feature Paper
  • Review
  • Open Access
27 Citations
15,154 Views
26 Pages

Bovine Colostrum Applications in Sick and Healthy People: A Systematic Review

  • Monica Guberti,
  • Stefano Botti,
  • Maria Teresa Capuzzo,
  • Sara Nardozi,
  • Andrea Fusco,
  • Andrea Cera,
  • Laura Dugo,
  • Michela Piredda and
  • Maria Grazia De Marinis

25 June 2021

Colostrum is the first secretion of mammalian glands during the early period after birth giving. Its components are biologically active and have beneficial effects on new-born growth and well-being. Bovine colostrum has the highest concentration of t...

  • Case Report
  • Open Access
5 Citations
4,705 Views
6 Pages

Blood-Stained Colostrum: A Rare Phenomenon at an Early Lactation Stage

  • Wszołek Katarzyna,
  • Pięt Małgorzata,
  • Więckowska (Pająk) Agata,
  • Meissner Wioletta,
  • Mazela Jan,
  • Rybicka Katarzyna and
  • Wilczak Maciej

6 February 2022

The phenomenon described in the literature as rusty pipe syndrome is a rare condition (the estimated incidence is 0.1% in the population of breastfeeding women) where the prenatal milk and the colostrum are rust- or blood-colored. Due to the rare occ...

  • Article
  • Open Access
6 Citations
3,119 Views
11 Pages

Evaluation of Parity Effect on Characteristics and Minerals in Buffalo (Bubalus Bubalis) Colostrum and Mature Milk

  • Zhigao An,
  • Gan Luo,
  • Shanshan Gao,
  • Xinxin Zhang,
  • Chao Chen,
  • Zhiqiu Yao,
  • Junwei Zhao,
  • Haimiao Lv,
  • Kaifeng Niu and
  • Liguo Yang
  • + 1 author

20 March 2023

Colostrum is a vital performance for buffaloes and potentially functional foods in the future. Therefore, this study aimed to evaluate the difference between the parity of buffalo colostrum and mature milk. Twenty pregnant buffaloes (primiparous = 10...

  • Article
  • Open Access
24 Citations
9,870 Views
11 Pages

Online Video Instruction on Hand Expression of Colostrum in Pregnancy is an Effective Educational Tool

  • Therese A. O’Sullivan,
  • Joy Cooke,
  • Chris McCafferty and
  • Roslyn Giglia

19 April 2019

The use of antenatal colostrum expression in the weeks prior to birth may help improve long-term breastfeeding, but few large-scale studies exist. Typically, antenatal colostrum expression instruction relies on face-to-face education, making large in...

  • Article
  • Open Access
6 Citations
5,395 Views
13 Pages

Mycobacterium avium Subspecies paratuberculosis DNA and Antibodies in Dairy Goat Colostrum and Milk

  • Karianne Lievaart-Peterson,
  • Saskia Luttikholt,
  • Maaike Gonggrijp,
  • Robin Ruuls,
  • Lars Ravesloot and
  • Ad P. Koets

29 November 2019

Mycobacterium avium subspecies paratuberculosis (MAP) is endemic in the Dutch dairy goat population causing economic loss, and negatively influencing welfare. Moreover, there are concerns about a potential zoonotic risk. Therefore the industry’...

  • Article
  • Open Access
4 Citations
3,117 Views
13 Pages

22 April 2024

The objective of this dairy farm study was to investigate the preweaning health, performance, immunity, and enteric pathogen shedding in calves supplemented with colostrum during five days after birth compared to calves not supplemented with colostru...

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