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28 Results Found

  • Article
  • Open Access
3 Citations
4,171 Views
14 Pages

Non-Medical Factors Associated with the Outcome of Treatment of Chronic Non-Malignant Pain: A Cross-Sectional Study

  • Irena Kovačević,
  • Višnja Majerić Kogler,
  • Valentina Krikšić,
  • Boris Ilić,
  • Adriano Friganović,
  • Štefanija Ozimec Vulinec,
  • Jadranka Pavić,
  • Milan Milošević,
  • Petra Kovačević and
  • Davorina Petek

Background: Chronic pain is a global public health issue with increasing prevalence. Chronic pain causes sleep disorder, reactive anxiety, and depression, impairs the quality of life; it burdens the individual and society as a whole. The aim of this...

  • Article
  • Open Access
718 Views
18 Pages

Relationship Between Hybrid Arts-Based CBT-CP Intervention and Personality Dimensions in Patients with Non-Malignant Chronic Pain: Evidence from a Non-Randomized Control Trial

  • Asimina Kalmanti,
  • Vasiliki Yotsidi,
  • Athanasios Douzenis,
  • Vasiliki Moraiti,
  • Aikaterini Malafanti and
  • Ioannis Michopoulos

Background: Optimal coping with chronic pain (CP) has a positive impact on minimizing the barriers to patients’ quality of life. Mindfulness-based approaches have been shown to improve emotional regulation and coping strategies in CP management...

  • Review
  • Open Access
27 Citations
23,679 Views
14 Pages

Integrated Approach to Chronic Pain—The Role of Psychosocial Factors and Multidisciplinary Treatment: A Narrative Review

  • Irena Kovačević,
  • Jadranka Pavić,
  • Biljana Filipović,
  • Štefanija Ozimec Vulinec,
  • Boris Ilić and
  • Davorina Petek

Background: Chronic non-malignant pain represents a growing global public health priority. Chronic pain is multifactorial, with numerous biological, psychological, and social factors contributing to this pain syndrome. It affects not only the patient...

  • Article
  • Open Access
8 Citations
4,372 Views
11 Pages

Chronic Non-Malignant Pain in Patients with Cancer Seen at a Timely Outpatient Palliative Care Clinic

  • David Hui,
  • Eman Abdelghani,
  • Joseph Chen,
  • Shiva Dibaj,
  • Donna Zhukovsky,
  • Rony Dev,
  • Kimberson Tanco,
  • Ali Haider,
  • Ahsan Azhar and
  • Akhila Reddy
  • + 8 authors

15 January 2020

Palliative care is seeing cancer patients earlier in the disease trajectory with a multitude of chronic issues. Chronic non-malignant pain (CNMP) in cancer patients is under-studied. In this prospective study, we examined the prevalence and managemen...

  • Article
  • Open Access
8 Citations
7,961 Views
14 Pages

Chronic non-malignant pain (CNMP) is commonly managed by General Practitioners (GPs) in primary care. Analgesics are the mainstay of CNMP management in this setting. Selection of medications by GPs may be influenced by micro factors which are relevan...

  • Article
  • Open Access
5 Citations
4,641 Views
21 Pages

Multimodal Interventions to Improve the Management of Chronic Non-Malignant Pain in Primary Care Using Participatory Research

  • Yolanda Morcillo-Muñoz,
  • Maria Holgado Jiménez Castellano,
  • Francisco Jose Díaz Exposito,
  • Antonio Jose Sanchez-Guarnido,
  • Miguel Gimenez Alcantara and
  • Maria Isabel Baena-Parejo

26 August 2021

Background: The use of diverse therapies combined with a multidisciplinary approach and prevention initiatives for patients with chronic non-malignant pain (CNMP) can improve health and have a positive impact on psychotropic drug use and the self-man...

  • Article
  • Open Access
467 Views
15 Pages

Healthcare Providers’ Perspectives on the Involvement of Mental Health Providers in Chronic Pain Management

  • Aziza Ali Alenezi,
  • Amin K. Makhdoom,
  • Rehab Abdullah Alanazi,
  • Fahad Saad Z. Alanazi,
  • Yusef Muhana Alenezi,
  • Zaid Alkhalfi Alanazi,
  • Naglaa A. Bayomy and
  • Manal S. Fawzy

16 October 2025

Background/Objectives: Chronic non-malignant pain (CNMP) affects 46.4% of adults in Saudi Arabia and often requires interdisciplinary care, including mental health services. Despite this need, mental health integration remains limited. This study exp...

  • Article
  • Open Access
1 Citations
1,615 Views
9 Pages

Multidimensional Analysis of Quality of Life in Patients with Chronic Non-Cancer Pain and Short- and Long-Term Intrathecal Analgesic Therapy

  • Manuel Alejandro Sánchez-García,
  • Bernardino Alcázar-Navarrete,
  • Manuel Cortiñas-Saenz,
  • Nicolás Cordero Tous and
  • Rafael Gálvez Mateos

18 September 2024

Background: Intrathecal drug delivery (IDD) is part of the fourth analgesic step. Evidence on the quality of life of patients with refractory chronic non-cancer pain (CNCP) using these devices and their long-term outcomes is scarce. This study aims t...

  • Review
  • Open Access
5 Citations
3,641 Views
22 Pages

Cancer Pain and Non-Invasive Brain Stimulation—A Narrative Review

  • Valentina-Fineta Chiriac,
  • Daniel Ciurescu and
  • Daniela-Viorica Moșoiu

6 November 2023

Background and Objectives: Pain is the most prevalent symptom in cancer patients. There is a paucity of data regarding non-invasive brain stimulation (NIBS) for the treatment of chronic pain in patients with cancer. The purpose of this article is to...

  • Article
  • Open Access
8 Citations
3,951 Views
15 Pages

Pain Rehabilitation’s Effect on People in Chronic Pain: A Prospective Cohort Study

  • Hafdís Skúladóttir,
  • Amalia Björnsdottir,
  • Janean E. Holden,
  • Thóra Jenný Gunnarsdóttir,
  • Sigridur Halldorsdottir and
  • Herdis Sveinsdottir

Multidisciplinary long-term pain rehabilitation programs with a team of healthcare professionals are an integrated approach to treat patients with chronic non-malignant pain. In this longitudinal prospective cohort study, we investigated the long-ter...

  • Article
  • Open Access
7 Citations
2,890 Views
16 Pages

Chronic pain is a major public health issue. Mounting evidence suggests that interdisciplinary multimodal pain rehabilitation programs (IMMRPs) performed in specialist pain care are an effective treatment for patients with chronic pain, but the effec...

  • Article
  • Open Access
11 Citations
4,384 Views
9 Pages

Early Changes in Pain Acceptance Predict Pain Outcomes in Interdisciplinary Treatment for Chronic Pain

  • Thomas Probst,
  • Robert Jank,
  • Nele Dreyer,
  • Stefanie Seel,
  • Ruth Wagner,
  • Klaus Hanshans,
  • Renate Reyersbach,
  • Andreas Mühlberger,
  • Claas Lahmann and
  • Christoph Pieh

2 September 2019

Studies have shown that pain acceptance is associated with a better pain outcome. The current study explored whether changes in pain acceptance in the very early treatment phase of an interdisciplinary cognitive-behavioral therapy (CBT)-based treatme...

  • Review
  • Open Access
1 Citations
4,225 Views
25 Pages

The Challenge of Managing Neuropathic Pain in Children and Adolescents with Cancer

  • Flaminia Coluzzi,
  • Giulia Di Stefano,
  • Maria Sole Scerpa,
  • Monica Rocco,
  • Giovanni Di Nardo,
  • Alice Innocenti,
  • Alessandro Vittori,
  • Alessandro Ferretti and
  • Andrea Truini

29 January 2025

Neuropathic pain (NP) is a common complication associated with some types of childhood cancer, mainly due to nerve compression, chronic post-surgical pain, chemotherapy, and radiotherapy. NP is usually less responsive to traditional analgesics, and t...

  • Interesting Images
  • Open Access
4 Citations
10,462 Views
5 Pages

Sternocostoclavicular Hyperostosis: An Ill-Recognized Disease

  • Bolette Roed,
  • Tatiana Kristensen,
  • Søren Thorsen,
  • Klaus Poulsen Bloch and
  • Pia Afzelius

Sternocostoclavicular hyperostosis (SCCH) is an ill-recognized, rarely diagnosed disease. Today, SCCH is widely considered part of the synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome. SCCH develops over years with intermittent...

  • Review
  • Open Access
1 Citations
2,020 Views
14 Pages

Analysis of the Biopsychosocial Impacts Associated with Endometriosis to Improve Patient Care

  • Aniela Roxana Noditi,
  • Ioana-Stefania Bostan,
  • Francesca Scurtu,
  • Diana Ionescu,
  • Andra Maria Mehedintu,
  • Aida Petca,
  • Claudia Mehedintu,
  • Marinela Bostan and
  • Ana Maria Rotaru

21 March 2025

Endometriosis is a non-malignant, inflammatory condition that impacts individuals across various hormonal stages, including before their first menstruation, throughout their reproductive years, and after menopause. This condition arises when tissue r...

  • Review
  • Open Access
18 Citations
5,941 Views
13 Pages

Melorheostosis: A Review of the Literature and a Case Report

  • Sergiu Iordache,
  • Adrian Cursaru,
  • Bogdan Serban,
  • Mihai Costache,
  • Razvan Spiridonica,
  • Bogdan Cretu and
  • Catalin Cirstoiu

30 April 2023

Background and Objectives: Melorheostosis, also referred to in the literature as Leri’s disease, is an unusual mesenchymal dysplasia with the clinical appearance of benign sclerosing bone dysplasia; it frequently occurs in late adolescence. Any...

  • Case Report
  • Open Access
1 Citations
1,958 Views
11 Pages

Actinomycosis: Mimicking Malignancies in Multiple Anatomical Sites—A Three-Patient Case Series

  • John Fernando Montenegro,
  • Vanessa Correa Forero,
  • Yamil Liscano,
  • Andres Grueso Pineda,
  • Diana Marcela Bonilla Bonilla and
  • Paola Andrea Ruiz Jimenez

2 February 2025

Background and Objectives: Actinomycosis is a rare chronic contagion caused by Actinomyces spp. known for its ability to mimic malignant processes across various anatomical locations. Its clinical presentation can often resemble malignancies, Mycobac...

  • Article
  • Open Access
2 Citations
2,978 Views
21 Pages

Ulcerous lesions can arise in primary skin cancers and upon infiltration of the skin by malignant cells originating from other organs. These malignant fungating wounds are difficult to treat, and they cause pain, itching and malodor. Distressing malo...

  • Article
  • Open Access
6 Citations
1 Views
4 Pages

A Clinicopathological Study of Dyspeptic Subjects in Lagos, Nigeria

  • Ladi Hameed,
  • Charles Asabamaka Onyekwere,
  • Jesse Abiodun Otegbayo and
  • Fatimah B. Abdulkareem

The clinicopathological and endoscopic features of dyspepsia have not been well studied in Nigeria due to the high cost of gastroscopes and lack of the relevant expertise. This study was designed to highlight these features and possible risk factors....

  • Case Report
  • Open Access

Traumatic Ulcerative Granuloma with Stromal Eosinophilia Treated with Intralesional Injections of Triamcinolone Acetonide: A Case Report

  • Daniele Pergolini,
  • Angelo Purrazzella,
  • Mohamed Mohsen,
  • Cira Rosaria Tiziana Di Gioia,
  • Antonella Polimeni and
  • Gaspare Palaia

2 December 2025

Background: Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) of the oral cavity is a chronic, rapidly developing mucosal lesion with an unclear pathogenesis, manifesting as a solitary ulcer. Given the malignant clinical appearance of...

  • Article
  • Open Access
1 Citations
511 Views
12 Pages

Long-Term Efficacy of 5-ALA Photodynamic Therapy in Oral Lichen Planus Patients

  • Magdalena Sulewska,
  • Marta Wróblewska,
  • Patryk Wiśniewski,
  • Ewa Duraj,
  • Jagoda Tomaszuk,
  • Aleksandra Pietruska and
  • Małgorzata Pietruska

5 November 2025

Background: Oral lichen planus (OLP) is a chronic mucosal disease associated with a risk of malignant transformation. Although topical corticosteroids are the standard therapy, prolonged administration may result in local and systemic complications....

  • Review
  • Open Access
1,193 Views
26 Pages

26 September 2025

Primary aggressive oral lymphomas (PAOL) are a rare subset of extranodal non-Hodgkin lymphomas arising in the oral cavity without evidence of other systemic involvement at diagnosis. PAOL accounts for only about 2–3% of all lymphomas. They most...

  • Review
  • Open Access
2 Citations
2,825 Views
18 Pages

Challenges, Difficulties, and Delayed Diagnosis of Multiple Myeloma

  • Tugba Zorlu,
  • Merve Apaydin Kayer,
  • Nazik Okumus,
  • Turgay Ulaş,
  • Mehmet Sinan Dal and
  • Fevzi Altuntas

Background: Multiple myeloma (MM) is a heterogeneous plasma cell malignancy with non-specific symptoms and disease heterogeneity at clinical and biological levels. This non-specific set of symptoms, including bone pain, anemia, renal failure, hyperca...

  • Article
  • Open Access
1 Citations
949 Views
8 Pages

Analysis of 46 Cases of Spontaneous Perirenal Hemorrhage: A Retrospective Observational Study

  • Seon Beom Jo,
  • Sun Tae Ahn,
  • Mi Mi Oh,
  • Sung Joon Park,
  • Young-Hoon Yoon,
  • Jong Wook Kim and
  • Jung-Youn Kim

25 April 2025

Background: This study investigated the clinical features, underlying causes, and management of patients with spontaneous perirenal hemorrhage (Wunderlich syndrome; WS). Methods: We retrospectively reviewed the records of patients hospitalized for WS...

  • Review
  • Open Access
4 Citations
3,814 Views
13 Pages

Intestinal Obstruction as Initial Presentation of Idiopathic Portal and Mesenteric Venous Thrombosis: Diagnosis, Management, and Literature Review

  • Bogdan Stancu,
  • Alexandra Chira,
  • Horațiu F. Coman,
  • Florin V. Mihaileanu,
  • Razvan Ciocan,
  • Claudia D. Gherman and
  • Octavian A. Andercou

It is quite common for portal vein thrombosis to occur in subjects who present predisposing conditions such as cirrhosis, hepatobiliary malignancies, infectious or inflammatory abdominal diseases, or hematologic disorders. The incidence of idiopathic...

  • Article
  • Open Access
1 Citations
1,279 Views
17 Pages

Groove Pancreatitis in Focus: Tumor-Mimicking Phenotype, Diagnosis, and Management Insights

  • Marina Balaban,
  • Daniel Vasile Balaban,
  • George Mănucu,
  • Săndica Nicoleta Bucurică,
  • Raluca Simona Costache,
  • Florentina Ioniță-Radu,
  • Mariana Jinga and
  • Cristian Gheorghe

27 February 2025

Background/Objectives: Groove pancreatitis (GP) is an uncommon pancreatic condition implying a challenging differential diagnosis. This study aims to comprehensively evaluate the main risk factors, clinical presentation, imaging and endoscopic charac...

  • Review
  • Open Access

Comprehensive Overview of Current Pleural Drainage Practice: A Tactical Guide for Surgeons and Clinicians

  • Paolo Albino Ferrari,
  • Cosimo Bruno Salis,
  • Elisabetta Pusceddu,
  • Massimiliano Santoru,
  • Gianluca Canu,
  • Antonio Ferrari,
  • Alessandro Giuseppe Fois and
  • Antonio Maccio

2 December 2025

Introduction: Chest drainage is central to thoracic surgery, pleural medicine, and emergency care, yet practice remains heterogeneous in tube caliber, access, suction, device selection, and removal thresholds. This narrative review aims to synthesize...

  • Article
  • Open Access
1 Citations
708 Views
12 Pages

The “Spider Web” Technique in Difficult Chest Wall Reconstructions: A 5-Year Experience

  • Emanuel Palade,
  • Stefanie Schierholz,
  • Tobias Keck and
  • David Benjamin Ellebrecht

23 April 2025

Background/Objectives: Primary chest wall tumors or malignancies of adjacent organs with chest wall infiltration present a significant challenge for surgical resection and reconstruction. Larger defects involving the sternum, resections in the area o...