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59,744 Results Found

  • Review
  • Open Access
54 Citations
10,720 Views
29 Pages

Oxidation and Antioxidation of Natural Products in the Model Organism Caenorhabditis elegans

  • An Zhu,
  • Fuli Zheng,
  • Wenjing Zhang,
  • Ludi Li,
  • Yingzi Li,
  • Hong Hu,
  • Yajiao Wu,
  • Wenqiang Bao,
  • Guojun Li and
  • Huangyuan Li
  • + 1 author

Natural products are small molecules naturally produced by multiple sources such as plants, animals, fungi, bacteria and archaea. They exert both beneficial and detrimental effects by modulating biological targets and pathways involved in oxidative s...

  • Article
  • Open Access
1 Citations
1,699 Views
26 Pages

Analysis of Composition, Antioxidation, and Immunoregulation for Exopolysaccharide Produced by Dellaglioa algida

  • Yao Sun,
  • Tianhui Wei,
  • Tongqing Ma,
  • Jiaqi Guan,
  • Zhiwei Wang,
  • Zhiying Fan and
  • Jinzhu Song

Lactobacillus is a recognized probiotic and has been widely used in food and medicine. As a new type of low-temperature resistant Lactobacillus, the fermentation products of Dellaglioa algida have multiple physiological activities. This study focuses...

  • Article
  • Open Access
30 Citations
12,533 Views
17 Pages

Elucidating the Structure-Activity Relationships of the Vasorelaxation and Antioxidation Properties of Thionicotinic Acid Derivatives

  • Supaluk Prachayasittikul,
  • Orapin Wongsawatkul,
  • Apilak Worachartcheewan,
  • Chanin Nantasenamat,
  • Somsak Ruchirawat and
  • Virapong Prachayasittikul

6 January 2010

Nicotinic acid, known as vitamin B3, is an effective lipid lowering drug and intense cutaneous vasodilator. This study reports the effect of 2-(1-adamantylthio)nicotinic acid (6) and its amide 7 and nitrile analog 8 on phenylephrine-induced contracti...

  • Article
  • Open Access
34 Citations
5,107 Views
15 Pages

Correlation Analysis of Phenolic Contents and Antioxidation in Yellow- and Black-Seeded Brassica napus

  • Yue Wang,
  • Guisheng Meng,
  • Sailing Chen,
  • Yajie Chen,
  • Jinjin Jiang and
  • You-Ping Wang

Brassica napus L. is rich in phenolic components and it has natural antioxidant characteristics which are important to human health. In the present study, the total phenolic and flavonoid contents of developing seeds of yellow- and black-seeded B. na...

  • Article
  • Open Access
49 Citations
5,908 Views
11 Pages

Antioxidation and Melanogenesis Inhibition of Various Dendrobium tosaense Extracts

  • Chin-Feng Chan,
  • Chin-Tung Wu,
  • Wen-Ying Huang,
  • Wen-Shin Lin,
  • Han-Wei Wu,
  • Teng-Kuan Huang,
  • Min-Yun Chang and
  • Yung-Sheng Lin

This study investigated the polyphenol content, antioxidant activity, and inhibition ability of mushroom tyrosinase and melanogenesis of Dendrobium tosaense (DT) extract. Ground DT was extracted using deionized water (W) or 50% ethanol (50E) at room...

  • Article
  • Open Access
12 Citations
3,047 Views
12 Pages

Impact of Salinity Changes on the Antioxidation of Juvenile Yellowfin Tuna (Thunnus albacares)

  • Shengjie Zhou,
  • Ninglu Zhang,
  • Zhengyi Fu,
  • Gang Yu,
  • Zhenhua Ma and
  • Lei Zhao

To understand the impacts of salinity stress on the antioxidation of yellowfin tuna Thunnus albacares, 72 fishes (646.52 ± 66.32 g) were randomly divided into two treatments (32‰ and 29‰) and sampled at four time points (0 h, 12...

  • Article
  • Open Access
35 Citations
3,823 Views
12 Pages

1 November 2019

To investigate the effect of carboxymethylation and phosphorylation modification on Sepia esculenta ink polysaccharide (SIP) properties, this study prepared carboxymethyl SIP (CSIP) with the chloracetic acid method, and phosphorylated SIP (PSIP) with...

  • Article
  • Open Access
78 Citations
8,354 Views
14 Pages

17 October 2018

In this study, the aim was to investigate the effect of bergenin on immune function and antioxidation in cyclophosphamide (Cy)-induced immunosuppressed mice. Firstly, we estimated its effect on immune organs. Histological analysis and indexes of immu...

  • Article
  • Open Access
24 Citations
3,739 Views
18 Pages

Ammonia Toxicity in the Bighead Carp (Aristichthys nobilis): Hematology, Antioxidation, Immunity, Inflammation and Stress

  • Yuning Zou,
  • Weixing Chen,
  • Banghua Xia,
  • Yifang Xiang,
  • Zhentao Shen,
  • Ying Han and
  • Shuqun Xue

5 March 2023

Ammonia is one of the main environmental pollutants that affect the survival and growth of fish. The toxic effects on blood biochemistry, oxidative stress, immunity, and stress response of bighead carp (Aristichthys nobilis) under ammonia exposure we...

  • Article
  • Open Access
17 Citations
4,493 Views
15 Pages

11 August 2021

The study was conducted to explore actions of decanoic acid on regulating intestinal barrier and antioxidant functions in intestinal epithelium cells isolated from porcine jejunum (IPEC-J2) and C57/BL6 mice models. In vitro and vivo assays, mice and...

  • Article
  • Open Access
26 Citations
3,294 Views
14 Pages

Color Stability Enhancement and Antioxidation Improvement of Sanhua Plum Wine under Circulating Ultrasound

  • Zhiqian Wu,
  • Xusheng Li,
  • Yingyu Zeng,
  • Dongbao Cai,
  • Zhaojun Teng,
  • Qixia Wu,
  • Jianxia Sun and
  • Weibin Bai

13 August 2022

Anthocyanins contribute to the attractive color of fruit wine, and their excessive degradation is deleterious to quality, especially for wine with an inherently low anthocyanin content, such as Sanhua plum wine. Ultrasonic treatment is well recognize...

  • Article
  • Open Access
5 Citations
2,887 Views
14 Pages

Synergistic Lubrication and Antioxidation Efficacies of Graphene Oxide and Fullerenol as Biological Lubricant Additives for Artificial Joints

  • Qian Wu,
  • Honglin Li,
  • Liangbin Wu,
  • Zihan Bo,
  • Changge Wang,
  • Lei Cheng,
  • Chao Wang,
  • Chengjun Peng,
  • Chuanrun Li and
  • Bo Wu
  • + 2 authors

30 December 2022

The service life of artificial joints has gradually failed to meet the needs of patients. Herein, the synergistic lubrication and antioxidant efficacies of graphene oxide (GO) and fullerenol (Fol) as biological lubricant additives for artificial join...

  • Article
  • Open Access
28 Citations
4,248 Views
21 Pages

Plant Polyphenols Attenuate DSS-induced Ulcerative Colitis in Mice via Antioxidation, Anti-inflammation and Microbiota Regulation

  • Huan Chen,
  • Ying Li,
  • Jinrui Wang,
  • Tingting Zheng,
  • Chenyang Wu,
  • Mengyao Cui,
  • Yifan Feng,
  • Hanyi Ye,
  • Zhengqi Dong and
  • Yunjie Dang

The pathogenesis of ulcerative colitis (UC) is associated with inflammation, oxidative stress, and gut microbiota imbalance. Although most researchers have demonstrated the antioxidant bioactivity of the phenolic compounds in plants, their UC-curing...

  • Article
  • Open Access
6 Citations
3,041 Views
11 Pages

Effects of Myo-Inositol on the Growth Performance, Digestive Enzyme Activity, and Antioxidation of Juvenile Hucho taimen

  • Meiyan Zhang,
  • Xing Yang,
  • Changan Wang,
  • Baodi Shang,
  • Feng Zhao,
  • Hong Xu and
  • Qiyou Xu

22 November 2023

Hucho taimen is a cold-water fish with high economic value. Myo-inositol (MI) can accelerate lipid metabolism and promote growth in fish species. The present study aimed to assess the effect of MI on the growth performance, digestive enzyme activity,...

  • Article
  • Open Access
42 Citations
3,739 Views
15 Pages

Solubility, Antioxidation, and Oral Bioavailability Improvement of Mangiferin Microparticles Prepared Using the Supercritical Antisolvent Method

  • Mengran Liu,
  • Yankun Liu,
  • Yunlong Ge,
  • Zhaoliang Zhong,
  • Zijian Wang,
  • Tong Wu,
  • Xiuhua Zhao and
  • Yuangang Zu

In view of the poor water solubility and low oral bioavailability of mangiferin (MG), in this study, the supercritical antisolvent (SAS) technology was used to prepare mangiferin microparticles (MG MPs) with N,N-dimethylformamide (DMF) as solvent and...

  • Article
  • Open Access
6 Citations
3,935 Views
17 Pages

Promising Anti-Wrinkle Applications of Aromatic Extracts of Hedychium coronarium J. Koenig via Antioxidation and Collagenase Inhibition

  • Pattiya Tammasorn,
  • Wannaree Charoensup,
  • Anurak Bunrod,
  • Watchara Kanjanakawinkul and
  • Wantida Chaiyana

17 December 2023

This study aimed to extract aromatic compounds from the rhizomes, leaf sheaths, and leaves of Hedychium coronarium and investigate their chemical compositions, cosmetic/cosmeceutical activities, and irritation potency. The chemical compositions were...

  • Article
  • Open Access
10 Citations
3,001 Views
16 Pages

2 January 2023

Recent pharmacological studies have shown that dragon’s blood has an anti-cerebral ischemia effect. Loureirin C (LC), a kind of dihydrochalcone compound in dragon’s blood, is believed to be play an important role in the treatment of ische...

  • Article
  • Open Access
67 Citations
11,428 Views
11 Pages

Applications of Lactobacillus rhamnosus Spent Culture Supernatant in Cosmetic Antioxidation, Whitening and Moisture Retention Applications

  • Cheng-Chih Tsai,
  • Chin-Feng Chan,
  • Wen-Ying Huang,
  • Jin-Seng Lin,
  • Patty Chan,
  • Ho-Yen Liu and
  • Yung-Sheng Lin

15 November 2013

This study was aimed at investigating the antioxidant, whitening, and moisture-retention properties of Lactobacillus rhamnosus spent culture supernatant (Lr-SCS) in cosmetic applications. Results reveal that Lr-SCS effectively and gradually scavenge...

  • Article
  • Open Access
7 Citations
2,903 Views
16 Pages

This study highlights the dynamics of phenolic acids, antioxidation, and 4-vinylguaiacol in beer produced with dark purple rice malt, also known as Riceberry rice malt, as an adjunct and base malt. Riceberry rice malt substituted barley malt at 40% (...

  • Article
  • Open Access
45 Citations
4,546 Views
20 Pages

The Improvement of Nanoemulsion Stability and Antioxidation via Protein-Chlorogenic Acid-Dextran Conjugates as Emulsifiers

  • Chang Liu,
  • Hua Jin,
  • Yue Yu,
  • Jingying Sun,
  • Huanyu Zheng,
  • Yan Zhang,
  • Jing Xu and
  • Xiuqing Zhu

In this experiment, the peanut protein isolate (PPI), soybean protein isolate (SPI), rice bran protein isolate (RBPI), and whey protein isolate (WPI) were modified by linking chlorogenic acid covalently and linking dextran by Maillard reaction to pre...

  • Article
  • Open Access
15 Citations
3,055 Views
17 Pages

14 January 2023

Pancreatic cancer (PC) is one of the most aggressive solid malignancies with poor treatment response and low survival rates. Herbal medicines such as betulinic acid (BA) have shown potential in treating various solid tumours, but with limitations tha...

  • Article
  • Open Access
11 Citations
4,041 Views
18 Pages

26 July 2022

Natto is a famous traditional fermented food, but the influence of the fermentation process on the content and composition of soybean isoflavones and nutritional value is still unclear. In the present study, the variation in soybean isoflavones durin...

  • Article
  • Open Access
7 Citations
2,356 Views
18 Pages

Intervention of Dietary Protein Levels on Muscle Quality, Antioxidation, and Autophagy in the Muscles of Triploid Crucian Carp (Carassius carassius Triploid)

  • Zhimin He,
  • Yuyang Cai,
  • Yang Xiao,
  • Shenping Cao,
  • Gaode Zhong,
  • Xinting Li,
  • Yanfang Li,
  • Junhan Luo,
  • Jianzhou Tang and
  • Suchun Liu
  • + 2 authors

The aim of this study is to investigate the effect of dietary protein levels on flesh quality, oxidative stress, and autophagy status in the muscles of triploid crucian carp (Carassius carassius triploid), and the related molecular mechanisms. Six ex...

  • Article
  • Open Access
6 Citations
3,094 Views
16 Pages

Probiotics-Fermented Grifola frondosa Total Active Components: Better Antioxidation and Microflora Regulation for Alleviating Alcoholic Liver Damage in Mice

  • Xiao-Yu He,
  • Yu-Xian Zhu,
  • Xiao-Qin Jiang,
  • Fu-Rong Zhu,
  • Yi-Juan Luo,
  • Yu-Yang Qiu,
  • Zi-Rui Huang,
  • Bin Liu and
  • Feng Zeng

11 January 2023

Alcoholic liver damage is caused by long-term drinking, and it further develops into alcoholic liver diseases. In this study, we prepared a probiotic fermentation product of Grifola frondosa total active components (PFGF) by fermentation with Lactoba...

  • Article
  • Open Access
11 Citations
7,517 Views
21 Pages

Alopecia has gradually become a problem that puzzles an increasing number of people. Dermal papilla cells (DPCs) play an important role in hair follicle (HF) growth; thus, exploring the effective chemicals or natural extracts that can remediate the g...

  • Article
  • Open Access
91 Citations
8,963 Views
18 Pages

16 September 2018

Tomato juice was fermented by Lactobacillus plantarum and Lactobacillus casei to produce an innovative high-bioactivity probiotic beverage. The levels of lycopene, total carotenoids, ascorbic acid, total phenolic and volatile compounds, 1,1-diphenyl-...

  • Article
  • Open Access
16 Citations
3,225 Views
19 Pages

Physiological and RNA-Seq Analyses on Exogenous Strigolactones Alleviating Drought by Improving Antioxidation and Photosynthesis in Wheat (Triticum aestivum L.)

  • Miao Song,
  • Naiyue Hu,
  • Sumei Zhou,
  • Songxin Xie,
  • Jian Yang,
  • Wenqi Ma,
  • Zhengkai Teng,
  • Wenxian Liang,
  • Chunyan Wang and
  • Dexian He
  • + 3 authors

20 October 2023

Drought poses a significant challenge to global wheat production, and the application of exogenous phytohormones offers a convenient approach to enhancing drought tolerance of wheat. However, little is known about the molecular mechanism by which str...

  • Article
  • Open Access
165 Citations
25,214 Views
18 Pages

Kombucha tea is a refreshing beverage that is produced from the fermentation of tea leaves. In this study, kombucha tea was prepared using 1% green tea, oolong tea, and black tea, and 10% sucrose with acetic acid bacteria and yeast. The pH values of...

  • Article
  • Open Access
9 Citations
2,543 Views
16 Pages

31 January 2023

Organic iron is expected to replace inorganic iron used in diets as an iron source. Organic iron possesses high absorption efficiency and low fecal iron excretion. This study aims to study the effect of organic iron produced by Saccharomyces cerevisi...

  • Article
  • Open Access
395 Views
15 Pages

19 December 2025

Chloro-organophosphate ester (Cl-OPE) accumulation in soil and aquatic environments, and their potential hazard to crops, has attracted widespread attention. However, little is known about the potential adverse effects of Cl-OPEs on plants. Green oni...

  • Article
  • Open Access
31 Citations
6,145 Views
13 Pages

Antioxidation and Cytoprotection of Acteoside and Its Derivatives: Comparison and Mechanistic Chemistry

  • Xican Li,
  • Yulu Xie,
  • Ke Li,
  • Aizhi Wu,
  • Hong Xie,
  • Qian Guo,
  • Penghui Xue,
  • Yerkingul Maleshibek,
  • Wei Zhao and
  • Dongfeng Chen
  • + 1 author

23 February 2018

The study tried to explore the role of sugar-residues and mechanisms of phenolic phenylpropanoid antioxidants. Acteoside, along with its apioside forsythoside B and rhamnoside poliumoside, were comparatively investigated using various antioxidant ass...

  • Article
  • Open Access
15 Citations
3,204 Views
15 Pages

5 September 2023

This experiment aims to investigate the effects of partial replacement of fish meal (FM) by soybean meal (SBM) and/or fermented soybean meal (FSBM) on the growth, serum biochemistry, digestion, antioxidation, immunity, and mTOR signaling pathway of j...

  • Article
  • Open Access
11 Citations
3,966 Views
24 Pages

5 May 2024

Fish in aquatic ecosystems are often impacted by environmental stressors like temperature fluctuations and exposure to heavy metals. Chromium (Cr6+) is a known environmental pollutant that poses a threat to aquatic life. Various environmental factors...

  • Article
  • Open Access
7 Citations
3,671 Views
14 Pages

29 July 2023

Short-chain fructooligosaccharides (sc-FOS) are prebiotics beneficial to human health, which can be synthesized from raw material containing a high sucrose content. Sugarcane syrup (SS) without molasses removal contains sucrose as a major sugar and i...

  • Article
  • Open Access
16 Citations
3,380 Views
24 Pages

21 April 2023

This study aimed to investigate the pharmacological efficacy of gold nanoparticles (GNs) synthesized using a green route, employing the rhizome extract of Euphorbia wallichii (REEW) as a bioreductant and surface stabilizing agent. The GNs were charac...

  • Article
  • Open Access
10 Citations
2,998 Views
17 Pages

14 September 2022

The study was designed with a 2 × 2 factorial experiment to evaluate the effects of growth performance, immune function, antioxidant status, blood biochemical indexes, and hormone levels of donkeys in different housing and management systems in...

  • Article
  • Open Access
3 Citations
1,716 Views
14 Pages

This study aimed to explore the effects of Bacillus amyloliquefaciens (BA) as one woody forage addition (as a probiotic, 1 × 107 CFU/g) on tilapia (Oreochromis niloticus). Woody forage is one kind of fishery feed that could significantly enhanc...

  • Review
  • Open Access
178 Citations
26,178 Views
30 Pages

Oxidative Stress and Antioxidants—A Critical Review on In Vitro Antioxidant Assays

  • Raghavendhar R. Kotha,
  • Fakir Shahidullah Tareq,
  • Elif Yildiz and
  • Devanand L. Luthria

1 December 2022

Antioxidants have been widely studied in the fields of biology, medicine, food, and nutrition sciences. There has been extensive work on developing assays for foods and biological systems. The scientific communities have well-accepted the effectivene...

  • Article
  • Open Access
4 Citations
3,380 Views
22 Pages

Effect of Extracellular Matrix Stiffness on Candesartan Efficacy in Anti-Fibrosis and Antioxidation

  • Tong Zhu,
  • Jingjing Song,
  • Bin Gao,
  • Junjie Zhang,
  • Yabei Li,
  • Zhaoyang Ye,
  • Yuxiang Zhao,
  • Xiaogang Guo,
  • Feng Xu and
  • Fei Li

Myocardial fibrosis progression and imbalanced redox state are closely associated with increased extracellular matrix (ECM) stiffness. Candesartan (CAN), an angiotensin II (Ang II) receptor inhibitor, has shown promising anti-fibrosis and antioxidant...

  • Article
  • Open Access
37 Citations
5,100 Views
22 Pages

Novel Antioxidant Peptides from Pearl Shell Meat Hydrolysate and Their Antioxidant Activity Mechanism

  • Pantian Huang,
  • Jianyin Miao,
  • Jialing Li,
  • Yingkun Li,
  • Xianghua Wang,
  • Yan Yu and
  • Yong Cao

15 January 2023

Free radicals are associated with aging and many diseases. Antioxidant peptides with good antioxidant activity and absorbability are one of the hotspots in antioxidant researches. In our study, pearl shell (Pinctada martensii) meat hydrolysate was pu...

  • Article
  • Open Access
8 Citations
3,207 Views
19 Pages

22 February 2023

Ficus pandurata Hance (FPH) is a Chinese herbal medicine widely used for health care. This study was designed to investigate the alleviation efficacy of the low-polarity ingredients of FPH (FPHLP), prepared by supercritical CO2 fluid extraction techn...

  • Article
  • Open Access
374 Views
11 Pages

3 December 2025

The antioxidant properties of seamless knitted fabrics with antioxidant fibers determine their antioxidant effects. In this paper, we used five kinds of raw yarn materials, namely mint nylon filament, tea carbon nylon filament, coffee carbon nylon fi...

  • Article
  • Open Access
6 Citations
3,128 Views
16 Pages

Evaluation of Antioxidant Properties and Molecular Design of Lubricant Antioxidants Based on QSPR Model

  • Jianfang Liu,
  • Yaoyun Zhang,
  • Chenglingzi Yi,
  • Rongrong Zhang,
  • Sicheng Yang,
  • Ting Liu,
  • Dan Jia,
  • Qing Yang and
  • Shuai Peng

Two quantitative structure–property relationship (QSPR) models of hindered phenolic antioxidants in lubricating oils were established to help guide the molecular structure design of antioxidants. Firstly, stepwise regression (SWR) was used to f...

  • Perspective
  • Open Access
24 Citations
8,345 Views
13 Pages

Oxidative stress is closely linked to various diseases, and many studies have been conducted to determine how to reduce this stress. In particular, efforts are being made to find potential antioxidants from natural products. Studies have shown that r...

  • Article
  • Open Access
72 Citations
7,087 Views
10 Pages

Antiviral and Antioxidant Properties of Echinochrome A

  • Sergey A. Fedoreyev,
  • Natalia V. Krylova,
  • Natalia P. Mishchenko,
  • Elena A. Vasileva,
  • Evgeny A. Pislyagin,
  • Olga V. Iunikhina,
  • Vyacheslav F. Lavrov,
  • Oksana A. Svitich,
  • Linna K. Ebralidze and
  • Galina N. Leonova

15 December 2018

The aim of this study was to examine the in vitro antioxidant and antiviral activities of echinochrome A and echinochrome-based antioxidant composition against tick-borne encephalitis virus (TBEV) and herpes simplex virus type 1 (HSV-1). The antioxid...

  • Article
  • Open Access
41 Citations
6,244 Views
12 Pages

In this study, quantitative structure-activity relationship (QSAR) models were determined based on 91 antioxidant tripeptides. We firstly adopted the stepwise regression (SWR) method for selecting key variables without autocorrelation and then utiliz...

  • Review
  • Open Access
336 Citations
18,816 Views
24 Pages

Recent Developments in Effective Antioxidants: The Structure and Antioxidant Properties

  • Monika Parcheta,
  • Renata Świsłocka,
  • Sylwia Orzechowska,
  • Monika Akimowicz,
  • Renata Choińska and
  • Włodzimierz Lewandowski

15 April 2021

Since the last few years, the growing interest in the use of natural and synthetic antioxidants as functional food ingredients and dietary supplements, is observed. The imbalance between the number of antioxidants and free radicals is the cause of ox...

  • Article
  • Open Access
12 Citations
5,150 Views
17 Pages

Plasma Non-Enzymatic Antioxidant Capacity (NEAC) in Relation to Dietary NEAC, Nutrient Antioxidants and Inflammation-Related Biomarkers

  • Cayetano Javier Carrión-García,
  • Eduardo Jesús Guerra-Hernández,
  • Belén García-Villanova,
  • Mauro Serafini,
  • María-José Sánchez,
  • Pilar Amiano and
  • Esther Molina-Montes

(1) Background: Little is known about the interlinkages between dietary and plasma non-enzymatic antioxidant capacity (D-NEAC and P-NEAC, respectively) and the body’s antioxidant and inflammation response. Our aim was to explore these associati...

  • Article
  • Open Access
68 Citations
8,617 Views
18 Pages

20 July 2012

The objective of this work is to provide a theoretical basis for preparing peanut antioxidant hydrolysate in order to improve its antioxidant activities. Therefore, response surface methodology (RSM) based on the Box-Behnken design was used to optimi...

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