Search Results (550)

Urban coastal areas are increasingly vulnerable to compound flooding due to the convergence of extreme rainfall, storm surges, and infrastructure aging, especially in high-density settings. This study proposes and empirically validates a multi-scale strategy for enhancing urban flood resilience in the Macau Peninsula, a densely built coastal city with complex flood exposure patterns. Building on a previously developed network-based resilience assessment framework, the study integrates hydrodynamic simulation and complex network analysis to evaluate the effectiveness of targeted interventions, including segmented storm surge defense barriers, drainage infrastructure upgrades, and spatially optimized low-impact development (LID) measures. The Macau Peninsula was partitioned into multiple shoreline defense zones, each guided by context-specific design principles and functional zoning. Based on our previously developed flood simulation framework covering extreme rainfall, storm surge, and compound events in high-density coastal zones, this study validates resilience strategies that achieve significant reductions in inundation extent, water depth, and recession time. Additionally, the network-based resilience index showed marked improvement in system connectivity and recovery efficiency, particularly under compound hazard conditions. The findings highlight the value of integrating spatial planning, ecological infrastructure, and systemic modeling to inform adaptive flood resilience strategies in compact coastal cities. The framework developed offers transferable insights for other urban regions confronting escalating hydrometeorological risks under climate change. Full article

Adolescent girls and young women (AGYW) in South Africa remain disproportionately affected by HIV due to a complex interplay of structural, social, and gender-based vulnerabilities. This study explored the experiences of AGYW who participated in a group-based HIV prevention intervention in three low-socio-economic communities—Soweto, Alexandra, and Orange Farm—in Gauteng Province, South Africa. The intervention integrated economic strengthening with HIV prevention education, delivered through structured, mentor-led group sessions. Using qualitative methods, in-depth interviews were conducted with 18 AGYW aged 15–24 to examine how participation empowered them to reduce HIV-related risks. The findings reveal that the intervention significantly enhanced participants’ self-awareness, assertiveness, and knowledge of Sexual and Reproductive Health (SRH), while fostering personal independence, goal setting, and agency. The group-based format also facilitated peer connection and created a safe space for challenging harmful gender norms, improving health-seeking behaviours, and navigating access to SRH services. Mentorship emerged as a critical enabler of impact, providing emotional support and trusted guidance. The study underscores the value of community group-based HIV prevention models that empower AGYW through social, economic, and gender-responsive approaches, offering practical insights for policy and programme design in resource-constrained settings. Full article

Understanding the degradation behavior of lithium-ion batteries under realistic application conditions is critical for the design and operation of Battery Energy Storage Systems (BESS). This research presents a modular, cell-level simulation framework that integrates electrical, thermal, and aging models to evaluate system performance in representative utility and residential scenarios. The framework is implemented using Python and allows time-series simulations to be performed under different state of charge (SOC), depth of discharge (DOD), C-rate, and ambient temperature conditions. Simulation results reveal that high-SOC windows, deep cycling, and elevated temperatures significantly accelerate capacity fade, with distinct aging behavior observed between residential and utility profiles. In particular, frequency modulation and deep-cycle self-consumption use cases impose more severe aging stress compared to microgrid or medium-cycle conditions. The study provides interpretable degradation metrics and visualizations, enabling targeted aging analysis under different load conditions. The results highlight the importance of thermal effects and cell-level stress variability, offering insights for lifetime-aware BESS control strategies. This framework serves as a practical tool to support the aging-resilient design and operation of grid-connected storage systems. Full article

This paper reports a study conducting an in-depth analysis of the impacts of ethical training on the adoption of AI tools among computer science students in higher vocational colleges. These students will serve as the pivotal human factor for advancing the field of AI. Aiming to explore practical models for integrating AI ethics into computer science education, the research seeks to promote more responsible and effective AI application and therefore become a positive influence in the field. Employing a mixed-methods approach, the study included 105 students aged 20–24 from a vocational college in Guangdong Province, a developed region in China. Based on the Unified Theory of Acceptance and Use of Technology 2 (UTAUT2) model, a five-point Likert scale was used to evaluate the participants’ perceptions of AI tool usage based on ethical principles. The Structural Equation Modeling (SEM) results indicate that while participants are motivated to adopt AI technologies in certain aspects, performance expectancy negatively impacts their intention and actual usage. After systematically studying and understanding AI ethics, participants attribute a high proportion of responsibility (84.89%) to objective factors and prioritized safety (27.11%) among eight ethical principles. Statistical analysis shows that habit (β = 0.478, p < 0.001) and hedonic motivation (β = 0.239, p = 0.004) significantly influence behavioral intention. Additionally, social influence (β = 0.234, p = 0.008) affects use behavior. Findings regarding factors that influence AI usage can inform a strategic framework for the integration of ethical instruction in AI applications. These findings have significant implications for curriculum design, policy formulation, and the establishment of ethical guidelines for AI deployment in higher educational contexts. Full article

International postgraduate students enrich higher education institutions and host societies, contributing economically, socially, and culturally. However, much less is known about how to improve their academic outcomes compared with their undergraduate counterparts. This study explores the impact of a non-traditional form of learning, a six-week immersive block model underpinned by guided, active learning pedagogy, on the academic success, satisfaction, and experiences of international postgraduate students at an Australian university. A convergent mix-methods design was used. Chi square tests and generalised estimating equations were used to compare the students’ success rates (N = 14,340) and unit satisfaction (N = 4903) in traditional semester and immersive block learning over five years. Qualitative insights were gathered via student focus groups (N = 9). Significant positive changes in success were observed after controlling for gender, age, discipline, and home region, with particularly strong positive effects for male and information technology students. Despite some challenges with depth of learning and placement organisation, focus group participants valued the clear timelines and flexible delivery, reporting that this supported effective time management and study-work–life-balance. Immersive block learning appears to be an effective strategy for transforming the experiences and outcomes of international postgraduate students in higher education. Full article

Background and Objectives: Orthodontic auxiliaries create plaque-retentive niches that may amplify biofilm accumulation and inflame adjacent soft tissues. While cross-sectional comparisons suggest higher palatal burden beneath acrylic elements, less is known about real-world patterns accumulated across years of routine care. We retrospectively evaluated periodontal and palatal outcomes, and, in a microbiology sub-sample, site-specific colonization, across three device types: molar bands, Nance buttons, and removable acrylic plates. Methods: We reviewed 2022–2025 records from a university orthodontic service, including consecutive patients aged 18–30 years with documented pre-placement and 6-month follow-up indices. Groups were bands (n = 92), Nance (n = 78), acrylic (n = 76). Standardized charted measures were abstracted: Plaque Index (PI), Gingival Index (GI), bleeding on probing (BOP%), probing depth (PD), and palatal erythema grade (0–3). A laboratory sub-sample (n = 174 visits) had archived swabs cultured for total aerobic counts (log₁₀ CFU/cm²) at the device, adjacent enamel, and palatal mucosa; Streptococcus mutans burden was available from qPCR (log₁₀ copies/mL). Results: Baseline characteristics were similar, except for longer wear at follow-up in Nance (10.1 ± 4.0 months) vs. bands (8.7 ± 3.2) and acrylic (6.9 ± 3.0; p < 0.001). At 6 months, device type was associated with greater worsening of PI and GI (both p < 0.001) and with higher palatal erythema (bands 0.7 ± 0.5; Nance 1.6 ± 0.8; acrylic 1.9 ± 0.7; p < 0.001). Microbiologically, palatal mucosal colonization was lowest with bands (3.3 ± 0.5), higher with Nance (4.9 ± 0.6), and highest with acrylic (5.0 ± 0.7; p < 0.001); S. mutans mirrored this gradient (p < 0.001). Palatal CFU correlated with erythema (ρ = 0.6, p < 0.001) and ΔGI (ρ = 0.5, p < 0.001). In adjusted models, acrylic (OR 6.7, 95% CI 3.5–12.8) and Nance (OR 4.9, 2.5–9.3) independently predicted erythema ≥2; recent prophylaxis reduced odds (OR 0.6, 0.3–0.9). Conclusions: In this single-center cohort, palate-contacting designs were associated with higher palatal biomass and erythema than bands. These associations support device-tailored hygiene considerations and proactive palatal surveillance, particularly for acrylic components. Full article

The primary objective of this research is to simplify and make the industrial manufacturing process of coated maraging steels more economical by combining the advantages of additive manufacturing with simultaneous bulk (aging) and surface (nitriding) treatment in an effective manner. With this aim, preliminary experiments were performed that demonstrated the hardness (and related microstructure) of an as-built MS1 maraging steel, produced by selective laser melting (SLM), is comparable to that of the bulk maraging steel products treated by conventional solution annealing. The direct aging of the solution-annealed and as-built 3D printed maraging steel resulted in similar hardness, indicating that the kinetics of the precipitation hardening process are identical for the steel in both conditions. This assumption was strengthened by a thermodynamic analysis of the kinetics and determination of the activation energy for precipitation hardening using Differential Scanning Calorimetry (DSC) measurements. Industrial target experiments were performed on duplex-coated SLM-printed MS1 steel specimens, which were simultaneously aged and salt-bath nitrided, followed by PVD coating with three different ceramic layers: DLC, CrN, and TiN. For reference, similar duplex-coated samples were used, featuring a bulk Böhler W720 maraging steel substrate that was solution annealed, precipitation hardened, and salt-bath nitrided in separate steps, following conventional procedures. The technological parameters (temperature and time) of the simultaneous nitriding and aging process were optimized by modeling the phase transformations of the entire heat treatment procedure using DSC measurements. A comparison was made based on the in-depth hardness profile estimated by the so-called expanding cavity model (ECM), demonstrating that the hardness of the surface layer of the coated composite material systems is determined solely by the type of the coatings and does not influenced by the type of the applied substrate materials (bulk or 3D printed) or its heat treatment (whether it is a conventional, multi-step treatment or a simultaneous nitriding + aging process). Based on the research work, a proposal is suggested for modernizing and improving the cost-effectiveness of producing aged, duplex-treated, wear-resistant ceramic-coated maraging steel. Full article

Flooding events have increased in frequency and severity worldwide in recent years, a trend that has been made worse by human activity and climate change. Floods are one of the world’s most dangerous natural catastrophes because of the serious risks they represent to property, human life, and cultural heritage. The necessity for efficient flood management techniques to reduce the growing dangers is what motivated this study. It specifically examines the flood risk in the Garyllis River Basin in Cyprus, a region recognized for it high susceptibility to extreme weather conditions Adopting an integrates approach that combines modeling tools and techniques, such as remote sensing, Geographic Information Systems (GIS) and hydraulic modeling, along with multiple data types of data and in situ measures, this study evaluates flood risk and proposed shelters and escapes routes for the worst-case scenarios. The research utilizes the open-access software HEC-RAS to simulate the spatio-temporal progression of surface water depth and water velocity for different return periods. The vulnerability levels are enumerated through a weighted linear combination of relevant factors, in specific population density and age distribution, according to the last official government reports. Exposure levels were calculated in terms of land value. For each flood component, all factors are assigned equal weighting coefficients. Subsequently, flood risk levels are assessed for each location as the product of hazard, vulnerability, and exposure levels. The validity of the proposed methodology is assessed by comparing the critical points identified during in situ visits with the flood risk level estimates. As a result, escape routes and refuge areas were proposed for the worst-case scenario. Full article

Background/Objectives: Electroencephalography (EEG) is increasingly used in pediatric anesthesia to detect abnormal brain activity such as burst suppression (BS), a marker of profound cortical inactivation. The objective of this study was to assess anesthetic depth using bilateral spectral edge frequency (SEF) and to determine the incidence of frontal cortical BS in young children undergoing cardiac surgery with extracorporeal circulation (ECC) under sevoflurane anesthesia. Methods: Twelve children, divided into two age groups (<12 months and 12–36 months), were included. EEG sensors were placed on the forehead and continuously monitored with SedLine^®. BS and SEF were analyzed using linear mixed-effects models, accounting for age group and repeated measurements across the procedure. Results: BS did not differ significantly over time. Across the full surgical procedure, higher SEF was associated with lower BS. However, children <12 months exhibited a stronger SEF–BS relationship, suggesting greater susceptibility to BS compared to older children. Before and during ECC, SEF and age group were not significantly related to BS. Random effects indicated moderate to substantial between-subject variability. Scatterplots showed a negative SEF–BS relationship overall, but weak and inconsistent associations during specific perioperative phases, underscoring the phase-dependent nature of SEF–BS dynamics. Conclusions: SEF is an age-sensitive marker of anesthetic depth during sevoflurane anesthesia with ECC, with children <12 months showing greater susceptibility to BS. These findings highlight the importance of individualized, age-adjusted anesthesia monitoring strategies in pediatric cardiac surgery. Full article

Phosphorus (P) is essential to life yet constrained by finite reserves, heterogeneous distribution, and strong chemical binding to soil minerals. Pedogenesis progressively alters the availability of P: in ‘young’ soils, P associated with Ca and Mg is relatively labile, while in ‘old’ soils, acidification and leaching deplete base cations, shifting P into organic matter and recalcitrant Al- and Fe-bound pools. Podzolized soils (Spodosols) provide a unique lens for studying this transition because podzolization vertically segregates these dynamics into distinct horizons. Organic cycling dominates the surface horizon, while downward translocation of Al, Fe, and humus creates a spodic horizon that immobilizes P through sorption and co-precipitation in amorphous organometal complexes. This spatial separation establishes two contrasting P pools—biologically dynamic surface P and mineral-stabilized deep P—that may be variably accessible to plants and microbes depending on depth, chemistry, and hydrology. We synthesize mechanisms of spodic P retention and liberation, including redox oscillations, ligand exchange, root exudation, and physical disturbance, and contrast these with strictly mineral-driven or biologically dominated systems. We further propose that podzols serve as natural experimental models for ecosystem aging, allowing researchers to explore how P cycling reorganizes as soils develop, how vertical stratification structures biotic strategies for nutrient acquisition, and how deep legacy P pools may be remobilized under environmental change. By framing podzols as a spatial analogue of long-term weathering, this paper identifies them as critical systems for advancing our understanding of nutrient limitation, biogeochemical cycling, and sustainable management of P in diverse ecosystems. Full article

Introduction: Ambiguous loss is a profound yet underexplored phenomenon in the lives of aging migrants. Older adults who have experienced migration often face disruptions to their sense of belonging, identity, and continuity across borders. These losses are compounded by aging, health challenges, and social isolation. Despite its significance, ambiguous loss among aging migrants has not been conceptually analyzed in depth, limiting the development of culturally responsive care practices. Aim: This concept analysis aimed to identify the defining attributes of ambiguous loss among aging migrants and to develop a conceptual definition that enhances our understanding of the phenomenon and informs future research and practice. Method: Walker and Avant’s eight-step concept analysis framework was applied to examine the concept of ambiguous loss in the context of aging migrants. A systematic keyword search was conducted across four databases (CINAHL, Medline, SCOPUS, PsycINFO), Google Scholar, and relevant gray literature, covering the years of 2010–2024. Covidence software supported the screening process. From 367 records identified, 146 underwent full-text review, and 74 met inclusion criteria. The analysis drew on literature synthesis, case exemplars, antecedents, consequences, and empirical referents. This review followed PRISMA (2020) reporting guidelines. Results: Four defining attributes of ambiguous loss among aging migrants were identified: (a) physical, social, and emotional loss; (b) displacement and loss of homeland; (c) erosion of social identity and agency; and (d) cultural and transnational bereavement. A conceptual definition emerged, describing ambiguous loss as a multifaceted experience of disconnection, intensified by aging, illness, economic hardship, and social isolation. The analysis also highlighted antecedents such as forced migration and health decline, as well as consequences including diminished well-being, resilience challenges, and barriers to integration. Conclusions: Ambiguous loss among aging migrants is a complex construct encompassing intertwined physical, social, and cultural dimensions of loss. This conceptual clarity provides a foundation for developing culturally responsive care models that promote adaptation, resilience, and social inclusion among older migrants. Full article

The Carpathian Basin holds exceptional significance for Quaternary research, particularly in loess studies. In this study, we attempted to create age-depth models based on age data from scientific journals to investigate accumulation rates. We examined eleven open profile sections for loess and paleosol, including seven in Hungary, two in Croatia, and two in Serbia. We demonstrated that radiocarbon age data are much more useful and reliable than OSL/IRSL data for this type of investigation. The results indicate that the Pécel, Dunaszekcső, Madaras and Katymár sections exhibit accumulation rates an order of magnitude higher than the other sections, exceeding one millimeter per year. These findings suggest that, owing to the basin’s geographic position, these areas were consistently exposed to dust deposition, irrespective of changes in climate or wind direction. A secondary accumulation maximum was also detected along the Katymár–Surduk axis, indicating an additional phase of intensified sediment deposition within this transect. The absence of a young sediment maximum in the Máza section is interpreted as resulting from a shift in prevailing wind direction, which caused the incoming dust to be intercepted by the Mecsek Mountains. Full article

Annuity insurance is a crucial financial tool for mitigating risks associated with aging, yet it has not gained significant traction in China’s insurance market, especially amid the challenges posed by an aging population. This study develops a discrete-time multi-period life-cycle model to analyze optimal annuity purchases for China’s middle-aged population under disability risk and explores in depth the impact and underlying mechanisms of disability risk on their annuity insurance purchase decisions. Disability is endogenized via two channels: financial-constraint effects (medical costs and pre-retirement income loss) and stochastic health state transitions with recovery and mortality. Using data from China Health and Retirement Longitudinal Study (2018–2020) to estimate age- and gender-specific transition matrices and data from China Household Finance Survey (2019) to link income with initial assets, we solve the model by the endogenous grid method and simulate actuarially fair annuities. The findings reveal substantial under-demand for annuities among China’s middle-aged population. Under inflation, the modest yield premium of annuities over inflation significantly depresses purchases by middle- and low-wealth households, while high-wealth individuals are jointly constrained by rapidly rising health expenditures and inadequate annuity returns. Notably, behavioral patterns could shift fundamentally under a hypothetical zero-inflation scenario. Full article

Background/Objectives: General anesthesia is occasionally required for cesarean delivery (CD). Propofol target-controlled infusion (TCI) enables dosing based on pharmacokinetic modeling. During the transition from induction to maintenance, infusion pauses. This simulation study assessed propofol from induction to delivery and the proportion of deliveries estimated during this pause. Methods: Surgical data from women undergoing CD were compiled, and the demographics were entered into a TCI pump using the Schnider model. Effect-site targets (6 and 8 mcg/mL) were simulated for induction, followed by 2.5 mcg/mL for maintenance. Outcomes were estimated propofol dose from induction to delivery and timing of delivery relative to infusion pause. Results: Among 50 women, the estimated mean propofol dose from induction to delivery was 19 ± 22 mg (0.2 ± 0.3 mg/kg) at 6 mcg/mL and 13 ± 17 mg (0.2 ± 0.2 mg/kg) at 8 mcg/mL. Delivery occurred during the infusion pause in 40% and 50% of cases, and it was more often in emergency than elective procedures. Emergency status, but not age or body mass index, predicted delivery during the pause. Conclusions: Standardized TCI with reduced effect-site targets for maintenance resulted in modest propofol administration between induction and delivery. These findings require confirmation in clinical studies, where dosing should be guided by depth-of-anesthesia monitoring. Full article

Background: currently, there is a growing trend toward multifunctional cosmetics, which combine several active ingredients in a single product to enhance efficacy and user convenience. As ingredients may influence one another, it is important to study the behavior of mixing multiple compounds in complex formulations, especially regarding their interaction with the skin. Piceatannol, for instance, is a naturally occurring stilbene recognized for its in vitro potent antioxidant, anti-inflammatory, and anti-aging activities, making it a promising candidate for dermocosmetic use in suncare. But despite its beneficial biological activities, its cutaneous permeation remains poorly understood, particularly when delivered from complex formulations containing multiple ingredients. Objectives: in this sense, this study aimed to evaluate the in vitro skin diffusion profile of piceatannol from a passion fruit seed extract (P_ext) incorporated into a topical base (B_em) or an organic sunscreen emulsion (O_em), with or without a spilanthol-rich Acmella oleracea extract (J_ext) used as a natural permeation enhancer. Methods: due to ethical and variability issues with human and animal skins, the Strat-M™ synthetic membrane was chosen as a standardized model for the in vitro skin permeation assays. Piceatannol localization within membrane layers was examined by confocal Raman microscopy (CRM), while compound identification in donor and receptor compartments was performed via UHPLC-DAD. Results: piceatannol from B_em was detected up to 140 µm from the Strat-M™ surface and exceeded 180 µm in depth when J_ext and organic sunscreens were included in the formulation. Notably, formulations containing J_ext and those based on O_em promoted enhanced accumulation in both the stratum corneum and deeper skin layers, suggesting an improved delivery potential in lipid-rich vehicles. Conclusions: even though some instability issues were observed, piceatannol penetration into Strat-M™ from the proposed formulations was confirmed, and the results provide a foundation for further research on its topical delivery, supporting the rational development of formulations capable of harnessing its demonstrated biological properties. Full article