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  • Article
  • Open Access
284 Views
22 Pages

Genome-Wide Identification of NF-YA Transcription Factors in Strawberry and Their Responses to Salt Stress

  • Jiajie Yu,
  • Xiang Zhang,
  • Shuang Wang,
  • Dian Wang,
  • Yingzhu Gao and
  • Xiaohong Li

12 May 2026

Nuclear Factor Y (NF-Y) transcription factor family plays essential roles in plant growth, development, and abiotic stress responses. However, the NF-YA subfamily in cultivated strawberry (Fragaria × ananassa) has not been systematically charac...

  • Article
  • Open Access
4 Citations
1,433 Views
18 Pages

28 November 2024

Nuclear Factor Y A (NF-YA) transcription factors are widely involved in multiple plant biological processes, such as embryogenesis, abscisic acid signaling, and abiotic stress response. This study presents a comprehensive genome-wide identification a...

  • Article
  • Open Access
30 Citations
6,207 Views
18 Pages

NF-YA Overexpression in Lung Cancer: LUSC

  • Eugenia Bezzecchi,
  • Mirko Ronzio,
  • Diletta Dolfini and
  • Roberto Mantovani

17 November 2019

The CCAAT box is recognized by the trimeric transcription factor NF-Y, whose NF-YA subunit is present in two major splicing isoforms, NF-YAl (“long”) and NF-YAs (“short”). Little is known about the expression levels of NF-Y su...

  • Article
  • Open Access
33 Citations
4,984 Views
17 Pages

NF-YA Overexpression in Lung Cancer: LUAD

  • Eugenia Bezzecchi,
  • Mirko Ronzio,
  • Valentina Semeghini,
  • Valentina Andrioletti,
  • Roberto Mantovani and
  • Diletta Dolfini

14 February 2020

The trimeric transcription factor (TF) NF-Y regulates the CCAAT box, a DNA element enriched in promoters of genes overexpressed in many types of cancer. The regulatory NF-YA is present in two major isoforms, NF-YAl (“long”) and NF-YAs (&l...

  • Article
  • Open Access
24 Citations
4,065 Views
16 Pages

NF-Y Overexpression in Liver Hepatocellular Carcinoma (HCC)

  • Eugenia Bezzecchi,
  • Mirko Ronzio,
  • Roberto Mantovani and
  • Diletta Dolfini

1 December 2020

NF-Y is a pioneer trimeric transcription factor formed by the Histone Fold Domain (HFD) NF-YB/NF-YC subunits and NF-YA. Three subunits are required for DNA binding. CCAAT-specificity resides in NF-YA and transactivation resides in Q-rich domains of N...

  • Article
  • Open Access
3 Citations
1,897 Views
19 Pages

Genome-Wide Identification and Expression Analysis of NF-YA Gene Family in the Filling Stage of Wheat (Triticum aestivum L.)

  • Yang Zhang,
  • Yanmin Xu,
  • Yulu Mao,
  • Xiaodi Tan,
  • Yuan Tian,
  • Xiaofei Ma,
  • Hutai Ji and
  • Dingyi Zhang

27 December 2024

The NF-YA gene family is a highly conserved transcription factor that plays a crucial role in regulating plant growth, development, and responses to various stresses. Despite extensive studies in multiple plants, there has been a dearth of focused an...

  • Article
  • Open Access
11 Citations
4,991 Views
21 Pages

The Switch from NF-YAl to NF-YAs Isoform Impairs Myotubes Formation

  • Debora Libetti,
  • Andrea Bernardini,
  • Sarah Sertic,
  • Graziella Messina,
  • Diletta Dolfini and
  • Roberto Mantovani

24 March 2020

NF-YA, the regulatory subunit of the trimeric transcription factor (TF) NF-Y, is regulated by alternative splicing (AS) generating two major isoforms, “long” (NF-YAl) and “short” (NF-YAs). Muscle cells express NF-YAl. We ablat...

  • Article
  • Open Access
4 Citations
2,916 Views
16 Pages

23 September 2022

The NF-YA gene family is a class of conserved transcription factors that play important roles in plant growth and development and the response to abiotic stress. Poplar is a model organism for studying the rapid growth of woody plants that need to co...

  • Review
  • Open Access
14 Citations
4,207 Views
16 Pages

Gene expansion is a common phenomenon in plant transcription factor families; however, the underlying molecular mechanisms remain elusive. Examples of gene expansion in transcription factors are found in all eukaryotes. One example is plant nuclear f...

  • Article
  • Open Access
2 Citations
1,583 Views
24 Pages

13 June 2025

Genome editing has revolutionized plant science, providing an unprecedented ability to precisely manipulate plant genomes. For this study, genome editing was utilized to target and modify the NF-YA8 transcription factor (TF) in tomato plants (Solanum...

  • Article
  • Open Access
9 Citations
3,711 Views
19 Pages

miR156-SPL and miR169-NF-YA Modules Regulate the Induction of Somatic Embryogenesis in Arabidopsis via LEC- and Auxin-Related Pathways

  • Katarzyna Nowak,
  • Anna M. Wójcik,
  • Katarzyna Konopka,
  • Alicja Jarosz,
  • Katarzyna Dombert and
  • Małgorzata D. Gaj

25 August 2024

The embryogenic transition of plant somatic cells to produce somatic embryos requires extensive reprogramming of the cell transcriptome. The prominent role of transcription factors (TFs) and miRNAs in controlling somatic embryogenesis (SE) induction...

  • Article
  • Open Access
15 Citations
4,007 Views
23 Pages

Genome-Wide Identification, Characterization and Expression Analysis of Plant Nuclear Factor (NF-Y) Gene Family Transcription Factors in Saccharum spp.

  • Peter Swathik Clarancia,
  • Murugan Naveenarani,
  • Jayanarayanan Ashwin Narayan,
  • Sakthivel Surya Krishna,
  • Prathima Perumal Thirugnanasambandam,
  • Ramanathan Valarmathi,
  • Giriyapur Shivalingamurthy Suresha,
  • Raju Gomathi,
  • Raja Arun Kumar and
  • Chinnaswamy Appunu
  • + 4 authors

25 May 2023

Plant nuclear factor (NF-Y) is a transcriptional activating factor composed of three subfamilies: NF-YA, NF-YB, and NF-YC. These transcriptional factors are reported to function as activators, suppressors, and regulators under different developmental...

  • Article
  • Open Access
1 Citations
1,106 Views
19 Pages

8 October 2025

Miscanthus, a perennial grass, is renowned for its remarkable tolerance to abiotic stress. Excessive levels of drought severely impair plant growth and yield. Plant nuclear factor Y (NF-Y) transcription factors (TFs) play pivotal roles in regulating...

  • Article
  • Open Access
5 Citations
2,451 Views
22 Pages

Zea mays (maize) is a staple food, feed, and industrial crop. Heat stress is one of the major stresses affecting maize production and is usually accompanied by other stresses, such as drought. Our previous study identified a heterotrimer complex, ZmN...

  • Article
  • Open Access
13 Citations
2,762 Views
19 Pages

Nuclear factor Y (NF-Y) transcription factors play an essential role in regulating plant growth, development, and stress responses. Despite extensive research on the NF-Y gene family across various species, the knowledge regarding the NF-Y family in...

  • Article
  • Open Access
3 Citations
2,336 Views
18 Pages

Genome and Transcriptome Analysis of NF-Y Transcription Factors in Sweet Potato under Salt Stress

  • Bei Liang,
  • Jiayun Wu,
  • Ye Chen,
  • Bei Wang,
  • Feiyan Gao,
  • Yongping Li and
  • Guopeng Zhu

Nuclear factor Y (NF-Y) is a heterotrimeric complex composed of three unique subunits: NF-YA, NF-YB, and NF-YC. This transcription factor complex binds to the CCAAT box of eukaryotic promoters, playing a crucial role in various biological processes i...

  • Article
  • Open Access
13 Citations
5,419 Views
21 Pages

Structural Basis of Inhibition of the Pioneer Transcription Factor NF-Y by Suramin

  • Valentina Nardone,
  • Antonio Chaves-Sanjuan,
  • Michela Lapi,
  • Cristina Airoldi,
  • Andrea Saponaro,
  • Sebastiano Pasqualato,
  • Diletta Dolfini,
  • Carlo Camilloni,
  • Andrea Bernardini and
  • Marco Nardini
  • + 2 authors

29 October 2020

NF-Y is a transcription factor (TF) comprising three subunits (NF-YA, NF-YB, NF-YC) that binds with high specificity to the CCAAT sequence, a widespread regulatory element in gene promoters of prosurvival, cell-cycle-promoting, and metabolic genes. T...

  • Article
  • Open Access
13 Citations
4,316 Views
22 Pages

Transcriptional Regulation of Female and Male Flower Bud Initiation and Development in Pecan (Carya illinoensis)

  • Yifei Xie,
  • Zhiying Hou,
  • Miao Shi,
  • Qiaoyan Wang,
  • Zhengfu Yang,
  • Kean-Jin Lim and
  • Zhengjia Wang

20 March 2023

Pecan (Carya illinoensis) nuts are delicious and rich in unsaturated fatty acids, which are beneficial for human health. Their yield is closely related to several factors, such as the ratio of female and male flowers. We sampled and paraffin-sectione...

  • Article
  • Open Access
16 Citations
3,370 Views
18 Pages

Genome-Wide Identification and Chilling Stress Analysis of the NF-Y Gene Family in Melon

  • Meng Li,
  • Qingjie Du,
  • Juanqi Li,
  • Hu Wang,
  • Huaijuan Xiao and
  • Jiqing Wang

The nuclear factor Y (NF-Y) transcription factor contains three subfamilies: NF-YA, NF-YB, and NF-YC. The NF-Y family have been reported to be key regulators in plant growth and stress responses. However, little attention has been given to these gene...

  • Article
  • Open Access
7 Citations
2,328 Views
17 Pages

Nuclear factor Ys (NF-Ys) are heterotrimeric transcription factors that specifically bind to CCAAT boxes present in numerous eukaryotic promoters. In plants, NF-Y proteins consist of the following three subunits: NF-YA, NF-YB, and NF-YC, each encoded...

  • Article
  • Open Access
6 Citations
3,785 Views
13 Pages

Genome-Wide Identification and Analysis of the NF-Y Transcription Factor Family in Medicago sativa L.

  • Tingting Song,
  • Jiawei Li,
  • Yuying Yuan,
  • Jinqiu Yu,
  • Yuqi Cao,
  • Hua Cai and
  • Guowen Cui

23 May 2022

The nuclear factor Y (NF-Y) gene family is an important transcription factor family consisting of three subfamilies, NF-YA, NF-YB and NF-YC, which are widely involved in plant growth and development, stress responses and other processes. In this stud...

  • Article
  • Open Access
1,795 Views
17 Pages

28 August 2025

This study addresses the role of cytosine methylation in the fine-tuning of flowering time under water deficit in Arabidopsis thaliana. A drm1 drm2 cmt3 (ddc) triple methylation mutant was used together with the Col-0 wild type. The plants were grown...

  • Article
  • Open Access
22 Citations
3,645 Views
22 Pages

26 September 2021

Nuclear Factor-Y (NF-Y) transcription factors play vital roles in plant abiotic stress response. Here, the NF-Y family in Brassica napus, which is hyper-sensitive to nitrogen (N) deprivation, was comprehensively identified and systematically characte...

  • Article
  • Open Access
3 Citations
1,276 Views
17 Pages

17 February 2025

The nuclear factor Y (NF-Y) transcription factor family identified in plant organisms consists of NF-YA, NF-YB, and NF-YC subunits, known for their pivotal role in regulating plant growth, development, and responses to environmental stress. Despite e...

  • Article
  • Open Access
31 Citations
5,863 Views
20 Pages

23 October 2018

In plants, the Nuclear Factor-Y (NF-Y) transcription factors (TFs), which include three distinct types of NF-YA, NF-YB, and NF-YC TFs, have been identified to play key roles in the regulation of various plant growth and developmental processes under...

  • Review
  • Open Access
71 Citations
6,809 Views
13 Pages

Crucial Abiotic Stress Regulatory Network of NF-Y Transcription Factor in Plants

  • Han Zhang,
  • Shujing Liu,
  • Tianmeng Ren,
  • Mengxue Niu,
  • Xiao Liu,
  • Chao Liu,
  • Houling Wang,
  • Weilun Yin and
  • Xinli Xia

23 February 2023

Nuclear Factor-Y (NF-Y), composed of three subunits NF-YA, NF-YB and NF-YC, exists in most of the eukaryotes and is relatively conservative in evolution. As compared to animals and fungi, the number of NF-Y subunits has significantly expanded in high...

  • Article
  • Open Access
25 Citations
4,765 Views
12 Pages

GmNF-YC4-2 Increases Protein, Exhibits Broad Disease Resistance and Expedites Maturity in Soybean

  • Seth O’Conner,
  • Wenguang Zheng,
  • Mingsheng Qi,
  • Yuba Kandel,
  • Robert Fuller,
  • Steven A. Whitham and
  • Ling Li

The NF-Y gene family is a highly conserved set of transcription factors. The functional transcription factor complex is made up of a trimer between NF-YA, NF-YB, and NF-YC proteins. While mammals typically have one gene for each subunit, plants often...

  • Article
  • Open Access
25 Citations
3,960 Views
15 Pages

In Silico Identification and Expression Analysis of Nuclear Factor Y (Nf-Y) Transcription Factors in Cucumber

  • Lianghai Chen,
  • Yong Zhou,
  • Wei Lai,
  • Lifang Hu,
  • Lunwei Jiang and
  • Shiqiang Liu

5 February 2020

The nuclear factor Y (NF-Y) transcription factors (TFs) play vital regulatory roles in diverse developmental processes and responses to abiotic stresses in plants. However, the NF-Y genes remain largely unknown in cucumber. In this study, based on ph...

  • Article
  • Open Access
12 Citations
2,929 Views
22 Pages

Identification of Competing Endogenous RNAs (ceRNAs) Network Associated with Drought Tolerance in Medicago truncatula with Rhizobium Symbiosis

  • Jiaxian Jing,
  • Peizhi Yang,
  • Yue Wang,
  • Qihao Qu,
  • Jie An,
  • Bingzhe Fu,
  • Xiaoning Hu,
  • Yi Zhou,
  • Tianming Hu and
  • Yuman Cao

17 November 2022

Drought, bringing the risks of agricultural production losses, is becoming a globally environmental stress. Previous results suggested that legumes with nodules exhibited superior drought tolerance compared with the non-nodule group. To investigate t...

  • Article
  • Open Access
6 Citations
3,767 Views
18 Pages

Genome-Wide Identification and Analysis of NF-Y Gene Family Reveal Its Potential Roles in Stress-Resistance in Chrysanthemum

  • Rongqian Hu,
  • Mengru Yin,
  • Aiping Song,
  • Zhiyong Guan,
  • Weimin Fang,
  • Fadi Chen and
  • Jiafu Jiang

Nuclear factor Y (NF-Y) is a class of transcription factors (TFs) with various biological functions that exist in almost all eukaryotes. In plants, heterotrimers composed of different NF-Y subunits are numerous and have different functions that can p...

  • Article
  • Open Access
12 Citations
3,180 Views
21 Pages

Nuclear factor YB (NF-YB) are plant-specific transcription factors that play a critical regulatory role in plant growth and development as well as in plant resistance against various stresses. In this study, a total of 49 NF-YB genes were identified...

  • Article
  • Open Access
2 Citations
2,773 Views
17 Pages

Genome-Wide Analysis of Nuclear factor-YC Genes in the Tea Plant (Camellia sinensis) and Functional Identification of CsNF-YC6

  • Shengxiang Chen,
  • Xujiao Wei,
  • Xiaoli Hu,
  • Peng Zhang,
  • Kailin Chang,
  • Dongyang Zhang,
  • Wei Chen,
  • Dandan Tang,
  • Qian Tang and
  • Liqiang Tan
  • + 1 author

Nuclear factor Y (NF-Y) is a class of transcription factors consisting of NF-YA, NF-YB and NF-YC subunits, which are widely distributed in eukaryotes. The NF-YC subunit regulates plant growth and development and plays an important role in the respons...

  • Article
  • Open Access
2 Citations
2,404 Views
23 Pages

Novel Core Gene Signature Associated with Inflammation-to-Metaplasia Transition in Influenza A Virus-Infected Lungs

  • Innokenty A. Savin,
  • Aleksandra V. Sen’kova,
  • Elena P. Goncharova,
  • Marina A. Zenkova and
  • Andrey V. Markov

7 November 2024

Respiratory infections caused by RNA viruses are a major contributor to respiratory disease due to their ability to cause annual epidemics with profound public health implications. Influenza A virus (IAV) infection can affect a variety of host signal...

  • Article
  • Open Access
6 Citations
2,767 Views
26 Pages

12 December 2022

Nuclear factor Y (NF-Y) is a heterotrimeric transcription factor that binds to the CCAAT cis-element in the promoters of target genes and plays critical roles in plant growth, development, and stress responses. In the present study, we aimed to re-ch...

  • Article
  • Open Access
1 Citations
510 Views
17 Pages

Genome-Wide Characterization of Nuclear Factor Y (NF-Y) Transcription Factors Gene Family in Cabbage (Brassica oleracea var. capitata L.) Uncovers Their Critical Roles in Salt Stress Tolerance

  • Xinyu Zhao,
  • Yiliao Feng,
  • Yuankang Wu,
  • Wenjing Ren,
  • Xuehui Yao,
  • Limei Yang,
  • Mu Zhuang,
  • Honghao Lv,
  • Yong Wang and
  • Yangyong Zhang
  • + 2 authors

27 February 2026

Nuclear Factor Y (NF-Y) transcription factors play pivotal roles in plant adaptation to abiotic stress, yet their genomic landscape and functional mechanisms in cabbage (Brassica oleracea var. capitata L.) remain underexplored. Here, we performed a g...

  • Article
  • Open Access
2 Citations
3,921 Views
14 Pages

13 December 2017

Autopolyploid plants and their organs are larger than their corresponding diploid ancestors, and they attract considerable attention for plant breeding. Paulownia is a fast-growing tree. To identify genes related to the biological characteristics of...

  • Article
  • Open Access
2 Citations
1,731 Views
14 Pages

Genome-Wide Identification and Expression Analysis of the NF-Y Transcription Factor Family in Prunus armeniaca

  • Jiangting Wu,
  • Yanguang He,
  • Lin Wang,
  • Han Zhao,
  • Nan Jiang,
  • Tana Wuyun and
  • Huimin Liu

10 November 2024

The nuclear factor Y (NF-Y) gene family plays important roles in regulating many of the biological processes of plants, including oil accumulation. The apricot (Prunus armeniaca) is one of the most commercially traded plants, and apricot kernel oil h...

  • Article
  • Open Access
12 Citations
6,437 Views
26 Pages

Integrative Transcriptomic and Metabolomic Analysis at Organ Scale Reveals Gene Modules Involved in the Responses to Suboptimal Nitrogen Supply in Tomato

  • Begoña Renau-Morata,
  • Rosa-Victoria Molina,
  • Eugenio G. Minguet,
  • Jaime Cebolla-Cornejo,
  • Laura Carrillo,
  • Raúl Martí,
  • Víctor García-Carpintero,
  • Eva Jiménez-Benavente,
  • Lu Yang and
  • Sergio G. Nebauer
  • + 3 authors

29 June 2021

The development of high nitrogen use efficiency (NUE) cultivars under low N inputs is required for sustainable agriculture. To this end, in this study, we analyzed the impact of long-term suboptimal N conditions on the metabolome and transcriptome of...

  • Article
  • Open Access
4 Citations
2,467 Views
18 Pages

In Silico Analysis of miRNA-mRNA Binding Sites in Arabidopsis thaliana as a Model for Drought-Tolerant Plants

  • Yryszhan Zhakypbek,
  • Aizhan Rakhmetullina,
  • Zhigerbek Kamarkhan,
  • Serik Tursbekov,
  • Qingdong Shi,
  • Fei Xing,
  • Anna Pyrkova,
  • Anatoliy Ivashchenko,
  • Bekzhan D. Kossalbayev and
  • Ayaz M. Belkozhayev

12 June 2025

Drought stress limits plant survival and yield in arid regions. Uncovering the molecular mechanisms of drought tolerance is key to developing resilient crops. This study used Arabidopsis thaliana as a model to perform an in silico analysis of miRNA&n...

  • Review
  • Open Access
1 Citations
1,328 Views
29 Pages

Epigenomics and Non-Coding RNAs in Soybean Adaptation to Abiotic Stresses

  • Kinga Moskal,
  • Bartosz Tomaszewski and
  • Maja Boczkowska

27 November 2025

This review presents soybean responses to drought, heat, and salinity within a signal–transcript–chromatin framework. In this framework, calcium/reactive oxygen species and abscisic acid cues converge on abscisic acid-responsive element b...

  • Article
  • Open Access
18 Citations
3,897 Views
20 Pages

Nuclear factor Y (NF-Y) is a heterotrimeric transcription factor that plays an important role in various biological processes in plants, such as flowering regulation, drought resistance, and salt stress. However, few in-depth studies investigated the...

  • Article
  • Open Access
6 Citations
2,691 Views
17 Pages

PDGFRβ Activation Induced the Bovine Embryonic Genome Activation via Enhanced NFYA Nuclear Localization

  • Chalani Dilshani Perera,
  • Muhammad Idrees,
  • Abdul Majid Khan,
  • Zaheer Haider,
  • Safeer Ullah,
  • Ji-Su Kang,
  • Seo-Hyun Lee,
  • Seon-Min Kang and
  • Il-Keun Kong

1 December 2023

Embryonic genome activation (EGA) is a critical step during embryonic development. Several transcription factors have been identified that play major roles in initiating EGA; however, this gradual and complex mechanism still needs to be explored. In...

  • Article
  • Open Access
1 Citations
2,704 Views
17 Pages

Comprehensive Analysis of the NF-YB Gene Family and Expression under Abiotic Stress and Hormone Treatment in Larix kaempferi

  • Lu Li,
  • Xi Ren,
  • Liying Shao,
  • Xun Huang,
  • Chunyan Zhang,
  • Xuhui Wang,
  • Jingli Yang and
  • Chenghao Li

NF-YB, a subfamily of Nuclear Factor Y (NF-Y) transcription factor, play crucial role in many biological processes of plant growth and development and abiotic stress responses, and they can therefore be good candidate factors for breeding stress-resi...

  • Article
  • Open Access
10 Citations
2,607 Views
17 Pages

Genome-Wide Identification and Drought Stress Response Pattern of the NF-Y Gene Family in Cymbidium sinense

  • Linying Wang,
  • Xuewei Zhao,
  • Ruiyue Zheng,
  • Ye Huang,
  • Cuili Zhang,
  • Meng-Meng Zhang,
  • Siren Lan and
  • Zhong-Jian Liu

Cymbidium sinense, a type of orchid plant, is more drought-resistant and ornamental than other terrestrial orchids. Research has shown that many members of the NUCLEAR FACTOR Y (NF-Y) transcription factor family are responsive to plant growth, develo...

  • Article
  • Open Access
13 Citations
2,702 Views
16 Pages

Genome-Wide Identification of the NF-Y Gene Family and Their Involvement in Bolting and Flowering in Flowering Chinese Cabbage

  • Zhehao Jiang,
  • Yuting Wang,
  • Wenxiang Li,
  • Yudan Wang,
  • Xiaojuan Liu,
  • Xi Ou,
  • Wei Su,
  • Shiwei Song and
  • Riyuan Chen

Flowering Chinese cabbage (Brassica campestris L. ssp. Chinensis var. utilis Tsen et Lee) is a widely consumed vegetable in southern China with significant economic value. Developing product organs in the flowering Chinese cabbage involves two key pr...

  • Article
  • Open Access
24 Citations
3,389 Views
23 Pages

24 December 2020

The nuclear factor Y (NF-Y) as a transcription factor plays an important role in plants growth and development, and response to stress. However, few genome-wide analyzes and functional research of the NF-Y family has been undertaken in apple (Malus d...

  • Article
  • Open Access
1,121 Views
20 Pages

Genome-Wide Identification of the CtNF-Y Gene Family and Expression Analysis of Different Flower Colours and Different Flowering Stages in Carthamus tinctorius L.

  • Jianhang Zhang,
  • Shuwei Qin,
  • Lili Wang,
  • Mengyuan Ma,
  • Wanting Yang,
  • Wenjie Shen,
  • Yaqian Lu,
  • Mingqiang Bao,
  • Meng Zhao and
  • Aiping Cao
  • + 2 authors

9 July 2025

Safflower (Carthamus tinctorius L.) is a plant in the family of Asteraceae, and the dried tubular flowers are used as medicine, which contain active ingredients such as safflower yellow pigment and safflower glycosides. They play important roles in m...

  • Article
  • Open Access
24 Citations
5,047 Views
16 Pages

6 March 2020

Nuclear Factor Ys (NF-Ys) are a class of heterotrimeric transcription factors that play key roles in many biological processes, such as abiotic stress responses, flowering time, and root development. The petunia (Petunia hybrida) is a model ornamenta...

  • Article
  • Open Access
1,600 Views
16 Pages

Despite the emerging evidence of the role of transcriptional regulators in schizophrenia as key molecular effectors responsible for the dysregulation of multiple biological processes, limited information is available for brain areas that control high...

  • Article
  • Open Access
8 Citations
4,199 Views
15 Pages

SP1 and NFY Regulate the Expression of PNPT1, a Gene Encoding a Mitochondrial Protein Involved in Cancer

  • Ignacio Ventura,
  • Fernando Revert,
  • Francisco Revert-Ros,
  • Lucía Gómez-Tatay,
  • Jesús A. Prieto-Ruiz and
  • José Miguel Hernández-Andreu

27 September 2022

The Polyribonucleotide nucleotidyltransferase 1 gene (PNPT1) encodes polynucleotide phosphorylase (PNPase), a 3′-5′ exoribonuclease involved in mitochondrial RNA degradation and surveillance and RNA import into the mitochondrion. Here, we...

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