You are currently on the new version of our website. Access the old version .

52 Results Found

  • Article
  • Open Access
15 Citations
3,434 Views
14 Pages

Wolfberry (Lycium barbarum) is a traditional cash crop in China and is well-known worldwide for its outstanding nutritional and medicinal value. Lycium ruthenicum is a close relative of Lycium barbarum but differs significantly in size, color, flavor...

  • Communication
  • Open Access
15 Citations
2,984 Views
6 Pages

23 November 2021

In this research, the effects of drying method, storage temperature, and color protector glucose on anthocyanin preservation in the Lycium ruthenicum Murr. fruit were studied. Compared with hot-air drying, vacuum freeze-drying preserved about 5.8-fol...

  • Article
  • Open Access
4 Citations
1,440 Views
13 Pages

Analysis of Phenotypic Trait Variation in Germplasm Resources of Lycium ruthenicum Murr.

  • Rong Yang,
  • Jinpu Li,
  • Haiguang Huang,
  • Xiuhua Wu,
  • Riheng Wu and
  • Yu’e Bai

28 August 2024

Exploring the phenotypic trait variation and diversity of Lycium ruthenicum germplasm resources can support selection, breeding, and genetic improvement, enhancing agricultural production. This study collected 213 wild Lycium ruthenicum seedlings fro...

  • Review
  • Open Access
17 Citations
3,329 Views
17 Pages

Research Progress on Active Ingredients and Product Development of Lycium ruthenicum Murray

  • Ming-Lu Xu,
  • Yun-Feng He,
  • Liang Xie,
  • Ling-Bo Qu,
  • Guang-Ri Xu and
  • Cheng-Xing Cui

Lycium ruthenicum Murray possesses significant applications in both food and medicine, including antioxidative, anti-tumor, anti-fatigue, anti-inflammatory, and various other effects. Consequently, there has been a surge in research endeavors dedicat...

  • Review
  • Open Access
16 Citations
2,499 Views
17 Pages

25 June 2024

Lycium ruthenicum Murr. is rich in polysaccharides, and the polysaccharides in Lycium ruthenicum Murr. (LRPS) have various bioactivities, such as antioxidant activity, anti-tumor activity, neuroprotective activity, and immunomodulatory activity. It h...

  • Article
  • Open Access
61 Citations
7,382 Views
16 Pages

Protective Effect of Lycium ruthenicum Murr. Against Radiation Injury in Mice

  • Yabin Duan,
  • Fan Chen,
  • Xingchen Yao,
  • Junbo Zhu,
  • Cai Wang,
  • Juanling Zhang and
  • Xiangyang Li

The protective effect of Lycium ruthenicum Murr. against radiation injury was examined in mice. Kunming mice were randomly divided into a control group, model group, positive drug group and L. ruthenicum high dose (8 g/kg), L. ruthenicum middle dose...

  • Article
  • Open Access
1,542 Views
19 Pages

Lycium ruthenicum Murray Anthocyanins Alleviate Aging Through SIRT1/P53 Signaling Pathway

  • Jialin Liang,
  • Zang Ga,
  • Jiaqin Wu,
  • Yingjie Wang,
  • Nanjia Dongzhu,
  • Rangzhong Qieyang,
  • Ping Li and
  • Sangduo Huaqian

Aging-related diseases have become a global health issue, with the escalating aging population leading to an increased disease incidence, placing immense pressure on individual health and society. Lycium ruthenicum Murray anthocyanins are hailed as t...

  • Article
  • Open Access
659 Views
17 Pages

Assessing the Impacts of Climate Change on the Potential Geographical Distribution of Lycium ruthenicum in China

  • Cheng Li,
  • Yuli Gu,
  • Bo Liu,
  • Kwok Pan Chun,
  • Thanti Octavianti,
  • Mou Leong Tan,
  • Yongping Wu and
  • Lei Zhong

9 October 2025

Understanding the climate change impacts on the geographical distribution of plant species is vital for biodiversity conservation. Lycium ruthenicum, a second-grade protected plant in China, holds considerable medicinal and ecological value; however,...

  • Review
  • Open Access
31 Citations
14,577 Views
18 Pages

27 September 2023

Lycium ruthenicum Murray (LRM; commonly known as black goji berry or black wolfberry), a plant in the Solanaceae family, grows in the deserts of China’s Qinghai–Tibet plateau. LRM is widely consumed in traditional Chinese medicine, and it...

  • Article
  • Open Access
1,284 Views
18 Pages

Light plays a crucial role in anthocyanin biosynthesis and color development in plants. Anthocyanins found in Lycium ruthenicum Murray are crucial for the plant’s defense against UV light and environmental stress, as well as for their economic...

  • Article
  • Open Access
20 Citations
3,567 Views
15 Pages

Preparation and Application of pH-Sensitive Film Containing Anthocyanins Extracted from Lycium ruthenicum Murr.

  • Yucong Zhao,
  • Le Gao,
  • Jing Wang,
  • Ziyan Xue,
  • Mengyao Zhang,
  • Xueli Ma,
  • Guohua Wang and
  • Shenghua Lv

18 May 2023

A new pH-sensitive film was developed using Artemisia sphaerocephala Krasch. gum (ASKG), soybean protein isolate (SPI), and natural anthocyanin extracted from Lycium ruthenicum Murr. The film was prepared by adsorbing anthocyanins dissolved in an aci...

  • Article
  • Open Access
21 Citations
4,286 Views
14 Pages

9 August 2019

Salt stress is a major constraint for many crops and trees. A wild species of Goji named Lycium ruthenicum is an important economic halophyte in China and has an extremely high tolerance to salinity. L. ruthenicum grows in saline soil and is known as...

  • Article
  • Open Access
11 Citations
2,195 Views
19 Pages

Proline Metabolism Process and Antioxidant Potential of Lycium ruthenicum Murr. in Response to NaCl Treatments

  • Richard John Tiika,
  • Huirong Duan,
  • Hongshan Yang,
  • Guangxin Cui,
  • Fuping Tian,
  • Yongtao He,
  • Yanjun Ma and
  • Yi Li

7 September 2023

Salinity influences the level of antioxidants and proline content, which are both involved in the regulation of stress responses in plants. To examine the interplay between the antioxidant system and proline metabolism in plant stress acclimation, ex...

  • Article
  • Open Access
15 Citations
3,277 Views
21 Pages

18 September 2022

Natural blue food colourant is rare. The aim of this work was to screen compounds from the common copigments that could improve the blue tones of anthocyanins (ACNs) and to investigate the effect of different copigments on the colour stability of ant...

  • Article
  • Open Access
9 Citations
3,135 Views
13 Pages

21 September 2021

Soil properties affect plant growth and cause variation in leaf functional traits. Lycium ruthenicum Murray is one of the desert dominant shrubs and halophytes in the lower reaches of Heihe River, Northwest China. We analyzed the trade-off relationsh...

  • Article
  • Open Access
821 Views
13 Pages

25 October 2025

[Introduction] The study aimed to investigate the protective effect of Lycium ruthenicum polysaccharides (LRPs) against carbon tetrachloride (CCl4)-induced acute liver injury (ALI). [Method] After LRP was extracted and characterized, a CCl4-induced c...

  • Article
  • Open Access
20 Citations
3,073 Views
14 Pages

Protective Effect of Lycium ruthenicum Polyphenols on Oxidative Stress against Acrylamide Induced Liver Injury in Rats

  • Hua Gao,
  • Yanzhong Xue,
  • Lingyu Wu,
  • Jinghong Huo,
  • Yufei Pang,
  • Jingxin Chen and
  • Qinghan Gao

25 June 2022

Acrylamide (ACR) is formed during tobacco and carbohydrate-rich food heating and is widely applied in many industries, with a range of toxic effects. The antioxidant properties of Lycium ruthenicum polyphenols (LRP) have been established before. This...

  • Article
  • Open Access
585 Views
16 Pages

14 November 2025

Basic leucine zipper (bZIP) transcription factors play pivotal roles in plant secondary metabolism, influencing the production of bioactive compounds that determine the medicinal value of plants. Despite their significance, a comprehensive genomic ov...

  • Article
  • Open Access
9 Citations
2,201 Views
19 Pages

11 September 2023

Light quality and sucrose-induced osmotic stress are known to cause anthocyanin synthesis in detached Lycium ruthenicum leaves. To identify the mechanisms by which the kind of light quality and sucrose concentration are induced, here, we conducted tr...

  • Article
  • Open Access
45 Citations
4,121 Views
19 Pages

The Main Anthocyanin Monomer from Lycium ruthenicum Murray Fruit Mediates Obesity via Modulating the Gut Microbiota and Improving the Intestinal Barrier

  • Peiyun Liu,
  • Wangting Zhou,
  • Weiqi Xu,
  • Yujia Peng,
  • Yamei Yan,
  • Lu Lu,
  • Jia Mi,
  • Xiaoxiong Zeng and
  • Youlong Cao

30 December 2021

Anthocyanins have been shown to exert certain antiobesity properties, but the specific relationship between anthocyanin-induced beneficial effects and the gut microbiota remains unclear. Petunidin-3-O-[rhamnopyranosyl-(trans-p-coumaroyl)]-5-O-(β...

  • Article
  • Open Access
26 Citations
3,443 Views
23 Pages

Cadmium (Cd) is a hazardous heavy metal environmental pollutant that has carcinogenic, teratogenic, and mutagenic properties. Excessive exposure to Cd can induce oxidative stress, which greatly harms the male reproductive system. Anthocyanins have re...

  • Article
  • Open Access
2 Citations
1,074 Views
15 Pages

12 September 2025

Background/Objectives: Acute lung injury (ALI) represents a life-threatening respiratory syndrome characterized by dysregulated pulmonary inflammation, alveolar-capillary barrier dysfunction, and gut-lung axis impairment. Although Lycium ruthenicum p...

  • Article
  • Open Access
30 Citations
2,897 Views
14 Pages

26 October 2022

In recent years, the relationship between Lycium ruthenicum Murr. anthocyanins (LRA) and health has attracted increasing attention. The purpose of this study is to investigate the anti-aging effect and mechanism of LRA through a D-galactose (DG)-indu...

  • Article
  • Open Access
666 Views
22 Pages

27 October 2025

Lycium ruthenicum leaves (LRL), as an agricultural by-product rich in bioactive compounds, can be used as an unconventional feedstuff in animal diets and have the potential to improve animal health. This study investigates the effects of dietary supp...

  • Article
  • Open Access
3 Citations
1,725 Views
21 Pages

26 November 2024

The aqueous extract of Lycium ruthenicum Murray (LRE) could attenuate neuroinflammation in mice induced by a high-fat and high-fructose diet (HFFD). Moreover, LRE could adjust bile acid (BA) metabolism and the gut microbiota. Behavioral tests reveale...

  • Article
  • Open Access
13 Citations
3,181 Views
17 Pages

20 October 2024

Exosome-like nanovesicles (ELNs) derived from plants are nanoscale vesicles isolated from edible plant sources. Lycium ruthenicum Murray (LRM) has garnered growing attention for its dietary value and therapeutic benefits. In this study, a PEG6000-bas...

  • Article
  • Open Access
11 Citations
2,514 Views
15 Pages

Protective Effects of Lycium ruthenicum Murray against Acute Alcoholic Liver Disease in Mice via the Nrf2/HO-1/NF-κB Signaling Pathway

  • Niantong Xia,
  • Zimian Ding,
  • Mingran Dong,
  • Shuyang Li,
  • Jia Liu,
  • Hongwei Xue,
  • Zhigang Wang,
  • Juan Lu and
  • Xi Chen

13 April 2024

Acute alcoholic liver disease (ALD) resulting from short-term heavy alcohol consumption has become a global health concern. Moreover, anthocyanins have attracted much attention for their ability to prevent oxidation and inflammation. The present work...

  • Article
  • Open Access
671 Views
20 Pages

18 November 2025

Lycium ruthenicum Murr. is a highly nutritional cash crop due to its fruit-abundant anthocyanins. With the development of the fruit, the color changes from green to dark purple and the anthocyanin content gradually increases. But the molecular mechan...

  • Article
  • Open Access
7 Citations
1,836 Views
24 Pages

6 August 2024

To delve into the growth and physiological adaptations exhibited by the economically vital black wolfberry (Lycium ruthenicum) upon inoculation with arbuscular mycorrhizal fungi (AMF) under varying levels of saline–alkaline stress A series of p...

  • Article
  • Open Access
37 Citations
4,335 Views
15 Pages

5 May 2022

Functional fermented fruit drinks are known worldwide for their health-promoting potential. Black wolfberry (BW) has high nutritional value, and its relative product development can be enriched through fermentation technology, so that its market migh...

  • Article
  • Open Access
9 Citations
2,949 Views
17 Pages

15 November 2023

Aging and age-related diseases are important study topics due to their associations with progressive physiological damage to genes, cells, tissues, and the entire organism, which ultimately affects the functional efficiency of organs. Lycium ruthenic...

  • Article
  • Open Access
786 Views
18 Pages

Genome-Wide SNP Analysis Reveals Population Structure and Genetic Diversity in Lycium ruthenicum Murr

  • Rong Yang,
  • Xiuhua Wu,
  • Yu’e Bai,
  • Yujiao He,
  • Sujuan Chang and
  • Long Hai

4 November 2025

Lycium ruthenicum Murr. (Black goji), a medicinal and economically valuable crop rich in bioactive compounds, remains genomically understudied despite its expanding cultivation. To overcome limitations of traditional markers in genetic diversity anal...

  • Article
  • Open Access
24 Citations
3,480 Views
10 Pages

16 May 2022

Lycium ruthenicum Murr. is one of the most important shrubs grown in northwest China. Healthy buds and leaves of L. ruthenicum Murr. were selected for the present study. Flower development was divided into six stages, namely, flower bud pre-different...

  • Article
  • Open Access
887 Views
20 Pages

Biphasic Salt Effects on Lycium ruthenicum Germination and Growth Linked to Carbon Fixation and Photosynthesis Gene Expression

  • Xinmeng Qiao,
  • Ruyuan Wang,
  • Lanying Liu,
  • Boya Cui,
  • Xinrui Zhao,
  • Min Yin,
  • Pirui Li,
  • Xu Feng and
  • Yu Shan

Since the onset of industrialization, the safety of arable land has become a pressing global concern, with soil salinization emerging as a critical threat to agricultural productivity and food security. To address this challenge, the cultivation of e...

  • Article
  • Open Access
12 Citations
4,288 Views
17 Pages

28 March 2021

With the intensification of desertification in northwest China, drought has become a serious environmental problem restricting plant growth and ecological restoration. Recently, dark septate endophytes (DSEs) have attracted more attention because of...

  • Article
  • Open Access
4 Citations
2,574 Views
11 Pages

The Protective Effect of Lycium Ruthenicum Murr Anthocyanins in Cr (VI)-Induced Mitophagy in DF-1 Cells

  • Shuhua Guo,
  • Mengzhu Qi,
  • Hongyan Li,
  • Yukun Cui,
  • Changxi Qi,
  • Guodong Cheng,
  • Meiyun Lv,
  • Pimiao Zheng and
  • Jianzhu Liu

25 July 2022

Cr (VI) is an extremely toxic environment and professional pollutant that seriously damages mitochondrial dysfunction when it enters a cell. Anthocyanins possess anti-oxidant, antiaging, and antifatigue properties. The regulatory effect of Lycium rut...

  • Article
  • Open Access
3 Citations
2,962 Views
24 Pages

Goat’s Milk Powder Enriched with Red (Lycium barbarum L.) and Black (Lycium ruthenicum Murray) Goji Berry Extracts: Chemical Characterization, Antioxidant Properties, and Prebiotic Activity

  • Danijel D. Milinčić,
  • Aleksandar Ž. Kostić,
  • Steva Lević,
  • Uroš M. Gašić,
  • Dragana D. Božić,
  • Relja Suručić,
  • Tijana D. Ilić,
  • Viktor A. Nedović,
  • Bojana B. Vidović and
  • Mirjana B. Pešić

29 December 2024

The current trend in food innovations includes developing products containing plant ingredients or extracts rich in bioactive compounds. This study aimed to prepare and characterize skimmed thermally treated goat’s milk powders enriched with ly...

  • Article
  • Open Access
19 Citations
3,312 Views
28 Pages

Lycium ruthenicum, a halophytic shrub, has been used to remediate saline soils in northwest China. However, little is known about its root-associated microbial community and how it may be affected by the plant’s growth cycle. In this study, we...

  • Review
  • Open Access
13 Citations
4,600 Views
23 Pages

Current Developments on Chemical Compositions, Biosynthesis, Color Properties and Health Benefits of Black Goji Anthocyanins: An Updated Review

  • Yuzhen Yan,
  • Tanzeela Nisar,
  • Zhongxiang Fang,
  • Lingling Wang,
  • Zichao Wang,
  • Haofeng Gu,
  • Huichun Wang and
  • Wenying Wang

Lycium ruthenicum is a therapeutic plant and its fruits (black goji) are commonly used as a traditional Chinese medicine. This review comprehensively discusses the recent research developments of black goji anthocyanins (BGAs), including chemical com...

  • Review
  • Open Access
1,012 Views
27 Pages

27 October 2025

The distinctive geographical environment of the Qinghai–Tibet Plateau has nurtured a variety of anthocyanin-rich berry plants. This review systematically summarizes the current state of research on anthocyanins obtained from Lycium ruthenicum M...

  • Article
  • Open Access
2 Citations
2,768 Views
17 Pages

This study examined the biological activity and genome of Bacillus cereus CDHWZ7 isolated from the root of Lycium ruthenicum in the Dachaidan saline area, Haixi Prefecture, Qinghai Province, China. The results revealed that B. cereus CDHWZ7 exhibited...

  • Article
  • Open Access
343 Views
15 Pages

15 December 2025

Background: Anthocyanins and proanthocyanidins (PAs), as flavonoid compounds with potent antioxidant activity, exhibit significant health-promoting and medicinal properties. Black wolfberry (Lycium ruthenicum Murr.) is renowned for its exceptional an...

  • Article
  • Open Access
13 Citations
5,154 Views
20 Pages

Black Goji Berry (Lycium ruthenicum) Juice Fermented with Lactobacillus rhamnosus GG Enhances Inhibitory Activity against Dipeptidyl Peptidase-IV and Key Steps of Lipid Digestion and Absorption

  • Kritmongkhon Kamonsuwan,
  • Vernabelle Balmori,
  • Marisa Marnpae,
  • Charoonsri Chusak,
  • Thavaree Thilavech,
  • Suvimol Charoensiddhi,
  • Scott Smid and
  • Sirichai Adisakwattana

With the global increase in hyperglycemia and hyperlipidemia, there is an urgent need to explore dietary interventions targeting the inhibition of dipeptidyl peptidase-IV (DPP-IV) and lipid digestion and absorption. This study investigated how Lactob...

  • Review
  • Open Access
3 Citations
4,624 Views
23 Pages

Polyphenolic Spectrum of Goji Berries and Their Health-Promoting Activity

  • Tunde Jurikova,
  • Simona Morvay Tinakova,
  • Jana Ziarovska,
  • Ladislav Szekeres,
  • Jiri Mlcek,
  • Katarina Fatrcova-Sramkova,
  • Zuzana Knazicka and
  • Sona Skrovankova

17 April 2025

A significant increase in interest in new, naturally occurring sources of antioxidants is evident not only in the food industry but also in the pharmaceutical and cosmetic industries. Plant sources such as fruits, both traditional and less common, ar...

  • Article
  • Open Access
43 Citations
6,181 Views
15 Pages

9 October 2020

Anthocyanins with catechol (cyanidin) or pyrogallol (delphinidin) moieties on the B-ring are known to chelate metals, resulting in bluing effects, mainly at pH ≤ 6. Metal interaction with petunidin, an O-methylated anthocyanidin, has not been well...

  • Article
  • Open Access
33 Citations
7,751 Views
14 Pages

The color expression of anthocyanins can be affected by a variety of environmental factors and structural characteristics. Anthocyanin acylation (type and number of acids) is known to be key, but the influence of acyl isomers (with unique stereochemi...

  • Article
  • Open Access
1 Citations
1,017 Views
15 Pages

8 April 2025

The CYP78A gene family, a plant-specific subfamily of cytochrome P450 enzymes, plays pivotal roles in plant growth, development, and stress responses. Although the CYP78A genes in many plants have been widely studied, little is known about them in Ly...

  • Review
  • Open Access
18 Citations
5,063 Views
22 Pages

31 May 2024

Natural plants contain numerous chemical compounds that are beneficial to human health. The berries from the Lycium genus are widely consumed and are highly nutritious. Moreover, their chemical constituents have attracted attention for their health-p...

  • Article
  • Open Access
14 Citations
3,502 Views
10 Pages

Anti-Influenza Activity of Medicinal Material Extracts from Qinghai–Tibet Plateau

  • Olga Kurskaya,
  • Elena Prokopyeva,
  • Hongtao Bi,
  • Ivan Sobolev,
  • Tatyana Murashkina,
  • Alexander Shestopalov,
  • Lixin Wei and
  • Kirill Sharshov

10 February 2022

To discover sources for novel anti-influenza drugs, we evaluated the antiviral potential of nine extracts from eight medicinal plants and one mushroom (Avena sativa L., Hordeum vulgare Linn. var. nudum Hook. f., Hippophae rhamnoides Linn., Lycium rut...

  • Article
  • Open Access
83 Citations
10,710 Views
15 Pages

Chemical Characterization, Antioxidant and Antimicrobial Properties of Goji Berries Cultivated in Serbia

  • Tijana Ilić,
  • Margarita Dodevska,
  • Mirjana Marčetić,
  • Dragana Božić,
  • Igor Kodranov and
  • Bojana Vidović

6 November 2020

Since the fruits of Lycium L. species (Fructus lycii, goji berries) are promoted as a “superfood” with plenty of health benefits, there is extensive research interest in their nutritional and phytochemical composition. In the present stud...

of 2